Clinical trials: Neurophysiology
Knowledge, Attitude
Pain Neurophysiology Education for Sport Therapy Students
The effect of a 70 minute Pain Neurophysiology Education session on Sport Therapy Students Knowledge, Attitudes and Clinical Behaviour Towards Athletes With Chronic Pain
- Conditions
- Knowledge, Attitude, Behavior
- Trial name
- NCT03002181
- Testing
- Education
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Teesside University
Healthy Subjects
The Impact of Pain Neuroscience Education on Physical Therapy Students' Knowledge, Attitudes, Beliefs, and Behaviors Towards Pain: A Randomized Controlled Trial
This study investigates the effect of pain neuroscience education (PNE) on pain knowledge, attitudes, beliefs and behaviors among undergraduate physiotherapy students in Jordan
- Trial name
- NCT06821022
- Testing
- Pain Neuroscience Education, Red Flags Education
- Where
- Jordan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hashemite University
Functional Neurological Disorder, Motor Symptoms
Investigating the Neurophysiology of the Motor System and the Feasibility of Vagus Nerve Stimulation in Functional Neurological Disorder (FND)
This clinical study will test if adding a non-invasive stimulation of the vagus nerve through the ear during physiotherapy brings an improvement to FND (Functional Neurological Disorder) patients with motor symptoms.
- Trial name
- TMS-VNS (NCT07710677)
- Testing
- Vagial Nerve Stimulation (VNS) active stimulation
- Where
- Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Fribourg
Neck Pain, Pain Knowledge
Reliability of the Neurophysiology of Pain Questionnaire in the Neck Pain the Cross-validation Study
The aim of this study is to study the validity and reliability of the Modified Pain Neurophysiology Questionnaire in patients with neck pain.
- Trial name
- NCT05606666
- Testing
- reliability of the NPQ
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Neck Pain, Chronic Pain
Brain, Brainstem, and Spinal Cord fMRI
New advances in medical imaging have allowed for the measurement of brain activity related to chronic pain. In addition to the brain, the investigators aim to use functional magnetic resonance imaging to investigate pain…
- Trial name
- NCT02356315
- Testing
- Functional Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Major Depressive Disorder, Depression
Investigating Biological Markers, Targets, and Intervention for Mood Disorders
This multi-modal methods study will investigate neurophysiological, endocrinological, cognitive, psycho-social-emotional markers of disease, and targets for integrative health treatments in mood disorders.
- Conditions
- Major Depressive Disorder, Depression, Stress
- Trial name
- NCT04632498
- Testing
- Mindfulness Based Intervention
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Healthy
Neurophysiological Effects of Mind-body Exercise in Healthy Adults
There is some clinical evidence showing that Baduanjin (BDJ) practice, a type of mind-body based physical exercise, can improve executive function (EF).
- Trial name
- NCT06337344
- Testing
- Baduanjin, Exercise, Video Viewing
- Where
- Hong Kong
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Adults With Variability in Their Mood
Restorative Neurophysiology: Backing up and Restoring the Brain (BandR)
Study to examine the extent to which neurophysiological states recorded for a specific person on one day can be induced on a subsequent day
- Trial name
- BandR (NCT07252011)
- Testing
- Transcranial alternating current stimulation (tACS), Neuro/biofeedback, Recall
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Neurophysiology, Physiology
Functional Implication of Corpus Callosum in Voluntary Strength in COPD Patients
Patients with COPD have lower capability of activating their muscles. At the cortical level, force production is not only controlled by contralateral primary motor cortex but also by ipsilateral motor cortex.
- Trial name
- NCT03807258
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- 2 sites in France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- 5 Santé
Aging
Development of Clinical Methods to Evaluate Neural Function in Aging
A primary focus of the University of Florida (UF) Claude D. Pepper Older Americans Independence Center (OAIC) is to build a comprehensive understanding of the causes and consequences of declining physical function and disability…
- Trial name
- MIND (NCT02073201)
- Testing
- High-functioning older adults, Lower-functioning older adults, Young adults
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Florida
Musculoskeletal Physiology
Training for Diagnosing Neurological Disorders
This training protocol has two objectives: 1) to train NINDS fellows in specialized techniques for diagnosing neurological disorders, and 2) to gather data from healthy volunteers and from patients with various disorders needed…
- Trial name
- NCT00132353
- Where
- United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Attention Deficit Hyperactivity Disorder (ADHD)
Train Your Brain and Exercise Your Heart? Advancing the Treatment for Attention Deficit Hyperactivity Disorder (ADHD)
Attention Deficit Hyperactivity Disorder (ADHD) is a developmental disorder that has a severe impact on a child's life and society. The core symptoms are attention problems, hyperactivity and impulsivity.
- Trial name
- NCT01363544
- Testing
- Neurofeedback, Exercise, methylphenidate
- Where
- 6 sites in Netherlands
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- R. van Mourik
Flatfoot, Flexible, Sports Physical Therapy
Neurophysiology-based Intervention of Foot Dysfunction in Sportive Children
The goal of the clinical trial study is to test the effect of the individual complex physiotherapy intervention program in the children actively playing soccer with flatfoot or valgus foot. The aims are: 1.
- Conditions
- Flatfoot, Flexible, Sports Physical Therapy, Child Development
- Trial name
- NCT05902091
- Testing
- Neurophysiology-based intervention
- Where
- Czechia
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
L-theanine
Theanine and Caffeine on Neurophysiology of Attention
L-theanine and caffeine are nutritional compounds that are naturally found in tea. Our recent findings using an EEG paradigm are consistent with the findings of others, indicating that intake of L-theanine and caffeine reduce the…
- Trial name
- THECNA (NCT02770105)
- Testing
- Theanine, Caffeine, Theanine-Caffeine Combination
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Spinal Cord Injury
Testosterone and Neural Function in Men With Spinal Cord Injury
Spinal cord injury (SCI) disrupts the nerves controlling movement, along with those that regulate functions like heart rate and blood pressure (known as the autonomic nervous system, or ANS).
- Trial name
- NCT06130449
- Testing
- Natesto testosterone intranasal gel, Ayr Saline Nasal Gel
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Neurodevelopmental Disorders
Individual Neurophysiological Sensory Profiles in People With and Without Neurodevelopmental Disorders
The goal of this observational study is to evaluate intra-individual neurophysiological variability in children and adults with and without NeuroDevelopmental Disorders (NDD), for several sensory modalities and types of…
- Trial name
- SensAUry (NCT07542977)
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Itching
A New Model to Induce Itch and Inflammation
This project aims to create a reliable, long-lasting itch model by synergistically combining thermal pre-conditioning with the application of histamine or cowhage.
- Trial name
- NCT07395882
- Testing
- Cowhage (Mucuna Pruriens), Histamine, Heat
- Where
- Denmark
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Alzheimer's Disease
Memory Imaging of Normal Aging
The purpose of this study is to develop imaging techniques that can distinguish functional brain changes in people at high risk for dementia years prior to onset of clinical memory problems from those with normal changes of aging.
- Trial name
- NCT00315575
- Testing
- BOLD and Perfusion brain MRI
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Chronic Pain, Pain, Chronic
Investigating Biological Targets, Markers, and Intervention for Chronic Pain
This multi-modal methods study will investigate neurophysiological, endocrinological, cognitive, psycho-social-emotional markers of chronic pain, and therapeutic targets using integrative health treatments.
- Conditions
- Chronic Pain, Pain, Chronic, Pain Syndrome, Pain, Neuropathic
- Trial name
- NCT04625504
- Testing
- Mindfulness Based Intervention
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Traumatic Brain Injury, Post-concussive Symptoms
MEG and DTI of Neural Function and Connectivity in Traumatic Brain Injury
The overall hypothesis is that the long-term cognitive and behavioral sequelae of traumatic brain injury (TBI) are due to selective disruption of the long association white matter tracts of the cerebral hemispheres, with…
- Trial name
- Dana-REAC (NCT01298557)
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco