Clinical trials: Neurorecovery
Stroke
Exercise Intensity Matters in Stroke Rehabilitation
The main objective of this multi-site project is to compare the effects of 12 weeks of HIIT vs. MICT on brain plasticity. The effects of HIIT vs.
- Trial name
- NCT03614585
- Testing
- 12 weeks of High-intensity Interval Training, 12 weeks of Moderate-Intensity Continuous Training
- Where
- 2 sites in Canada
- Volunteers
- 80 people
- Sponsor
- McGill University
Spinal Cord Injuries, Spinal Cord Trauma
Health Outcomes After Locomotor Training in Spinal Cord Injury
People with spinal cord injury (SCI) suffer from secondary health conditions that can result in undue physical challenges and impact participation in activities in everyday life.
- Trial name
- NCT02201173
- Testing
- Locomotor Training
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Stony Brook University
Stroke Rehabilitation, Stroke
Substrates for Post-Stroke Arm Rehabilitation
Difficulty moving the arm is very common and a major cause of disability after stroke. Although rehabilitation therapies (i.e., occupational and physical therapy) are the most common treatments used to improve arm motor function…
- Conditions
- Stroke Rehabilitation, Stroke, Neurorecovery
- Trial name
- SPARk (NCT06998485)
- Testing
- Arm Basis Training
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Spinal Cord Injuries
Feasibility of Early Gabapentin as an Intervention for Neurorecovery
The objective of the proposed study is to conduct the first ever prospective, dose-exploration trial to test the feasibility of early administration of gabapentin as an intervention for neurorecovery.
- Trial name
- NCT05302999
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- MetroHealth Medical Center
Spinal Cord Injuries
Spinal Cord Injury Neurorecovery Collaboration
SCINC is an adaptive design Master protocol that seeks to determine if there is "sufficient promise" of beneficial effect of treatment combinations to enhance motor recovery in pre-specified strata of people with a spinal cord…
- Trial name
- SCINC (NCT06871254)
- Testing
- Therapeutic Intermittent Hypoxia (TIH) + Exercise Training (ET)
- Where
- Australia
- Volunteers
- 24 people
- Sponsor
- University of Melbourne
Acute Spinal Cord Injury
Early FES Cycling in Acute Spinal Cord Injury for Neuromuscular Preservation and Neurorecovery
Spinal cord injury (SCI) is a devastating condition that often leads to paralysis and multiple health problems such as muscle wasting, bone loss and spasticity.
- Trial name
- NCT05255679
- Testing
- Early FES, Delayed FES
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of Alberta
Traumatic Brain Injury
The CAPTAIN Trial: Cerebrolysin Asian Pacific Trial in Acute Brain Injury and Neurorecovery
The purpose of this trial is to investigate safety and efficacy of Cerebrolysin as add-on therapy to standard care in patients with acute traumatic brain injury (TBI). The study duration for each patient is 180 days.
- Trial name
- CAPTAIN (NCT01606111)
- Testing
- Cerebrolysin, 0.9% NaCl, saline
- Where
- Hong Kong
- Volunteers
- 46 people
- Sponsor
- Ever Neuro Pharma GmbH
Stroke
Reaching the Unreached: Home-Based Telerehabilitation for Stroke Survivors
After a stroke, many people have trouble using their arms and hands. This can make daily tasks-like eating, dressing, or writing-very hard.
- Trial name
- NCT07467785
- Testing
- Standard of Care (SOC), Telerehabilitation with Tenzr
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Alberta
Stroke, Ischemic
Stroke Motor Rehabilitation and Recovery Study
SMaHRT (Stroke Motor reHabiliation and Recovery sTudy) is a longitudinal study aimed at understanding the natural history of upper extremity motor recovery after ischemic and hemorrhagic stroke.
- Trial name
- SMaHRT (NCT03485040)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Massachusetts General Hospital
Brain Concussion
The Effect of Exercise on Neurorecovery Following Mild Traumatic Brain Injury
The study is a "proof-of-principle" project to examine the safety and feasibility of implementing a 1-week aerobic exercise program in the post-acute phase after mild traumatic brain injury (mTBI).
- Trial name
- NCT02276079
- Testing
- Aerobic Exercise, Non-Aerobic Exercise
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Florida
Spinal Cord Injuries (SCI), Spinal Cord Injury
Guttmann NeuroRecovery - Viability, Safety, and Efficacy of Intrathecal Wharton's Jelly Mesenchymal Stem Cells and Transcutaneous Spinal Cord Stimulation in Chronic Spinal Cord Injury Rehabilitation
This clinical trial primarily aims to evaluate the safety and feasibility of a combined therapeutic approach for chronic spinal cord injury (SCI).
- Conditions
- Spinal Cord Injuries (SCI), Spinal Cord Injury, Traumatic Spinal Cord Injuries, Spinal Cord Disease
- Trial name
- GNR-SCI-01 (NCT06981338)
- Testing
- Allogeneic Wharton's jelly mesenchymal stem cells (WJ-MSCs)
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Institut Guttmann