Clinical trials: Neurorehabilitation
Stroke, Neurological Rehabilitation
Cross-sectoral Rehabilitation After Stroke (CRES)
Prospective cohort study during post stroke rehabilitation in hospital and municipality. Participants will be measured with accelerometers, tests in relation to physical function and qualitative interviews.
- Conditions
- Stroke, Neurological Rehabilitation, Patient Involvement
- Trial name
- CRES (NCT05566782)
- Where
- Denmark
- Volunteers
- 117 people
- Sponsor
- Nordsjaellands Hospital
Spinal Cord Injury Cervical
Prediction of Muscle Responsiveness to FES Therapy
Reduced arm and hand function has a significant impact on independence and quality of life after spinal cord injury. Functional electrical stimulation therapy (FES-T) is a treatment that can produce improvements in reaching and…
- Trial name
- NCT05462925
- Testing
- Functional electrical stimulation therapy.
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University Health Network, Toronto
Stroke, Gait Disorders, Neurologic
ZEPU AI9 Exoskeleton Rehabilitation Robot
The goal of this clinical trial is to learn whether the ZEPU AI9 lower limb exoskeleton robot is feasible, safe, and effective for people with walking difficulty caused by stroke, incomplete spinal cord injury, or orthopedic…
- Conditions
- Stroke, Gait Disorders, Neurologic, Spinal Cord Injuries, Incomplete, Postoperative Complication
- Trial name
- NCT07750808
- Testing
- ZEPU-AI9 Lower Limb Exoskeleton Gait Training, Standard-of-Care Rehabilitation
- Where
- Bangladesh
- Volunteers
- 36 people
- Sponsor
- Bangladesh Medical University
Dementia, Stroke
Music Therapy on Cognition in Neurorehabilitation
Music therapy has received more attention with its surging application in neuro-rehabilitation overseas. Given the dearth of music therapy and cognitive rehabilitation research conducted in Malaysia, this pilot study intended to…
- Conditions
- Dementia, Stroke, Traumatic Brain Injury
- Trial name
- NCT06156735
- Testing
- Passive Music Therapy (P), Active Music Therapy (A), Standard Care Control Condition (C)
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- University of Malaya
Stroke
Therapeutic Exercise for Patients With Stroke
The aim of this prospective, single-centre, non-randomized, single-arm interventional study is to evaluate changes in muscle strength, lower-limb functional capacity, aerobic endurance, and patient satisfaction following…
- Trial name
- EINTER (NCT07736794)
- Testing
- EINTER Therapeutic Exercise Programme
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Traumatic Brain Injury, Posttraumatic Confusional State
Amantadine for Treatment of Symptoms of the Post-traumatic Confusional State
Patients with traumatic brain injury often experience a period of acute confusion that may include agitation as they recover from their injuries.
- Conditions
- Traumatic Brain Injury, Posttraumatic Confusional State, Delirium
- Trial name
- NCT00693121
- Testing
- Amantadine hydrochloride
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Methodist Rehabilitation Center
Apathy, Stroke
Transcranial Direct Current Stimulation (tDCS) in Chronic Post-Stroke Apathy
The purpose of this study is to test the efficacy and safety of tDCS (Transcranial Direct Current Stimulation) on apathy in stroke patients.
- Trial name
- TDCS-PSA (NCT02915484)
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stony Brook University
Cerebrovascular Accident
Hybrid Approach to Unilateral vs. Bilateral Upper Limb Rehabilitation in Subacute and Chronic Stroke
In the unilateral vs. bilateral hybrid rehabilitation trials, we will conduct two separate clinical trials: one to recruit subacute stroke patients and another to recruit chronic stroke patients.
- Trial name
- NCT01908361
- Testing
- Unilateral Hybrid (InMotion3 plus CIT) Intervention, Bilateral Hybrid (BMT plus BAT) Intervention, Conventional Rehabilitation
- Where
- Taiwan
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Parkinson Disease, Telemedicine
Telerehabilitation for Parkinson's Disease
Our primary objective in this 10-week pilot study is to demonstrate the feasibility of using videoconferencing technology to provide Parkinson's Disease (PD) patients, alongside their supervising care partners, specialized…
- Trial name
- TelerehabPD (NCT04600011)
- Testing
- Physical and occupational therapy (PT/OT), Home Safety Evaluation (HSE)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Rush University Medical Center
Interventional Study
Physiological Responses in Robotic Neurorehabilitation
Robotic rehabilitation is very useful for improving functional recovery in neurological patients, there is not much evidence on its role in improving physiological responses (i.e.
- Trial name
- Lokophysio (NCT04035122)
- Testing
- Robotic Treatment, Conventional Treatment
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Stroke, Incomplete Spinal Cord Injury
ZEPU-AI5 Strength Training Study (ZEPUAI5RCT)
The goal of this clinical trial is to learn if robot-assisted lower-limb strength and gait training can improve safety, feasibility, and functional recovery in adults aged 18-60 years with lower-limb motor dysfunction due to…
- Conditions
- Stroke, Incomplete Spinal Cord Injury, Gait Impairment Following Orthopedic Surgery
- Trial name
- NCT07735702
- Testing
- Robotic lower-limb gait training (ZEPU-AI5), Standard-of-care rehabilitation (conventional physiotherapy)
- Where
- Bangladesh
- Volunteers
- 51 people
- Sponsor
- Bangladesh Medical University
Attention Deficit Hyperactivity Disorder
Multi-Component Training Versus Motor Learning Techniques in Adults With ADHD
This randomized clinical trial aims to compare the effects of multi-component training and motor learning techniques on attention, cognitive performance, and motor coordination in adults with Attention Deficit Hyperactivity…
- Trial name
- MCT-MLT (NCT07845981)
- Testing
- Multi-Component Training, Motor Learning Techniques
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Mild Cognitive Impairment
Noninvasive Dual-mode Stimulation Therapy for Neurorehabilitation in Mild Cognitive Impairment
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of mild cognitive impairment (MCI) patients' cognitive function by altering the cortical…
- Trial name
- NCT03647345
- Testing
- High-frequency rTMS on left DLPFC+anodal tDCS on right DLPFC, High-frequency rTMS on left DLPFC+cathodal tDCS on right DLPFC
- Where
- South Korea
- Volunteers
- 21 people
- Sponsor
- Samsung Medical Center
Post-stroke Fatigue
Post-Stroke Fatigue Perception Study (ReFast)
The goal of this observational study is to better understand fatigue after stroke. Many people feel ongoing tiredness months or years after a stroke. This fatigue may affect daily activities, work, and social life.
- Trial name
- ReFast (NCT07444151)
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- School of Health Sciences Geneva
Stroke
Precision Sensorimotor Neurorehabilitation Through Personalized Stimulation Loops
Stroke is the most common neurological disease in the elderly population and accounts for substantial disability and health care costs. Disability is largely driven by mobility deficits caused by impaired gait.
- Trial name
- StimuLOOP-S (NCT06466772)
- Testing
- Hyper-personalized feedback (HPF intervention), Targeted auditory stimulation during sleep (TASS verum intervention)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Spasticity, Stroke
Early Botulinum Toxin for Muscle Stiffness Reduction in First-Time Stroke Patients: Improving Recovery and Independence
This study examines the early use of botulinum toxin in patients recovering from their first stroke to help reduce muscle stiffness and improve mobility.
- Conditions
- Spasticity, Stroke, Neurological Rehabilitation
- Trial name
- EARLY BOT-SPAS (NCT06811142)
- Testing
- Botulinum Toxin Type A (BoNT-A)
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- Instituto Mexicano del Seguro Social
Neurologic Disorder, Subarachnoid Hemorrhage, Aneurysmal
Hippocampal Volume and Memory Functions in Aneurysmal Subarachnoid Hemorrhage
Neuropsychological and functional long-term consequences of subarachnoid hemorrhages (SAH) represent a great challenge, since sometimes considerable cognitive deficits occur without evidence of substantial brain damage.
- Trial name
- NCT04449666
- Testing
- Neuropsychological assessment and structural MRI
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Traumatic Brain Injury, Posttraumatic Stress Disorder
LED Treatment to Improve Cognition and Promote Recovery in TBI
This study investigates the efficacy of a novel neuromodulation treatment, light emitting diodes (LED), on cognition, neuropsychiatric status and quality of life in individuals with traumatic brain injury (TBI).
- Trial name
- LED-TBI (NCT02404402)
- Testing
- LED
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- VA Office of Research and Development
Neurological Rehabilitation, Stroke
Effects of Repetitive Transcranial Magnetic Stimulation Therapy on Lower Extremity Motor Development in Stroke Patients
The aim of our study is to investigate the effects of rTMS applications at different current frequencies (low frequency / intermittent (intermittent) theta burst (iTBS)) in stroke patients on lower extremity motor development…
- Conditions
- Neurological Rehabilitation, Stroke, Lower Extremity Problem, Quality of Life
- Trial name
- NCT05554861
- Testing
- Low Frequency rTMS Protocol, Intermittent Theta Burst Stimulation (iTBS) Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Afyonkarahisar Health Sciences University
Stroke, Perceptual Disorders
Dynamic Auditory Cueing for Spatial Neglect in Stroke
Spatial neglect is a common condition after stroke and can make it difficult for people to pay attention to one side of space. This problem can negatively affect daily activities and functional independence.
- Conditions
- Stroke, Perceptual Disorders, Spatial Neglect, Spatial Neglect After Stroke
- Trial name
- DAC-SN (NCT07507383)
- Testing
- Dynamic Auditory Cueing, Conventional Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Gazi University