Clinical trials: Neurorehabilitation
COVID-19 Pandemic
Respiratory Physiotherapy and Neurorehabilitation in Patients With Post-covid19 Sequelae.
The objectives are to reduce dyspnoea, increase exertional capacity, increase vital capacity and respiratory muscle strength. vital capacity and respiratory muscle strength.
- Trial name
- NCT05195099
- Testing
- respiratory treatment
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Universidad Católica de Ávila
Hand Transplantation, Peripheral Nerve Injuries
Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair
This study adopts a strategy that has arisen from basic neuroscience research on facilitating adaptive brain plasticity and applies this to rehabilitation to improve functional recovery in peripheral nervous system injuries…
- Conditions
- Hand Transplantation, Peripheral Nerve Injuries, Neurologic Rehabilitation
- Trial name
- NCT03610763
- Testing
- Transcranial Direct Current Stimulation, Modified Constraint Induced Movement Therapy
- Where
- 3 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of Missouri-Columbia
Stroke
Protocol Design of Hand Robotics Assisted Therapy in Patients With Different Severity of Stroke
Some studies have shown that the end-effector type of hand robotic-assisted therapy (RT) can effectively improve upper extremity (UE) motor function in patients with stroke.
- Trial name
- NCT04436627
- Testing
- Amadeo-assisted training-1, Amadeo-assisted training-2, Amadeo-assisted training-3
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Chang Gung Memorial Hospital
Stroke
ROOD's Sensory Motor Training in Sub-acute Stroke
The aim of this randomized controlled trial is to determine the effects of ROOD's sensory motor training along with Constraint Induced Movement Therapy (CIMT) in sub-acute stroke.
- Trial name
- NCT04173481
- Testing
- Rood's Group, Conventional Physical Therapy Group
- Where
- Pakistan
- Volunteers
- 29 people
- Sponsor
- Riphah International University
Cerebral Palsy, Walking, Difficulty
A Motor Learning Intervention to Target Walking Performance in Ambulant Children With Cerebral Palsy
The goal of this clinical trial is to learn if a new therapy approach to improve walking ability in children with Cerebral Palsy is acceptable to the children and the families in a community setting.
- Conditions
- Cerebral Palsy, Walking, Difficulty, Spastic Diplegia, Hemiplegic Cerebral Palsy
- Trial name
- MOBILE (NCT06454656)
- Testing
- MOBILE
- Where
- Ireland
- Volunteers
- 14 people
- Sponsor
- Royal College of Surgeons, Ireland
Ischemic Stroke, Upper Extremity Hemiparesis
Stroke Wearable Operative Rehabilitation Device Impact Trial
The objective of this study is to determine the impact of vibratory feedback on the quality and intensity of a common motor rehabilitation task of the upper-arm (hand-to-mouth) in stroke patients.
- Trial name
- SWORD-IT (NCT01967290)
- Testing
- Vibratory feedback and 3D movement analysis, Only 3D movement analysis
- Where
- 3 sites in Portugal
- Volunteers
- 44 people
- Sponsor
- Centro Hospitalar de Entre o Douro e Vouga
Dysphagia
Effects of Free Water Protocol on Inpatients in a Neurological Rehabilitation Setting
Inpatients in the neurology rehabilitation units at Riverview Health Center- people who are brain-injured and or who have had a stroke - often have dysphagia as a result of their condition.
- Trial name
- NCT01209910
- Testing
- Water
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Parkinson Disease, Freezing of Gait
Neurorehabilitation of Sequence Effect in Parkinson's Disease
The sequence effect (SE), defined as a reduction in amplitude of repetitive movements, is a common clinical feature of Parkinson's disease (PD), being a major contributor to freezing of gait (FOG).
- Trial name
- NCT04921748
- Testing
- Neurorehabilitation
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Parkinson Disease
Learning Potential of Patients With Parkinson's Disease After Two Weeks of Targeted Touchscreen Training
Parkinson's disease (PD) is characterized by severe motor and non-motor symptoms, including upper limb dysfunction. Due to the degradation of dopaminergic neurons in the striatum, PD patients experience difficulties with motor…
- Trial name
- NCT05696197
- Testing
- Targeted touchscreen training
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- KU Leuven
Multiple Sclerosis, Functional Neurological Disorders
Bridging Gaps in the Multidimensional Assessment and Management of Overlapping Symptoms in Multiple Sclerosis and Functional Motor Disorders: Prevalence and Rehabilitation Effectiveness
Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system that may cause a broad range of motor and non-motor symptoms.
- Trial name
- NCT07856485
- Testing
- Functional Motor Disorder-Specific Multidisciplinary Rehabilitation, Conventional Multiple Sclerosis Rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 192 people
- Sponsor
- IRCCS San Raffaele
Sleep Apnea, Stroke
Non-contact Sleep Apnea Identification in Neurological Rehabilitation
To improve the quality of medical care in the group of poststroke patients, we are planning to examine neurological patients in a rehabilitation clinic simultaneously with a non-contact method (Sleepiz One) and a standard…
- Trial name
- NCT04803552
- Testing
- Overnight sleep study with Sleepiz One and a respiratory polygraphy
- Where
- Switzerland
- Volunteers
- 67 people
- Sponsor
- Sleepiz AG
Multiple Sclerosis
Standardized Ambulatory Neurorehabilitation Program for Patients With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) and the most common cause of non-traumatic disability in young adults in western countries.
- Trial name
- "MS-Fit" (NCT02440516)
- Testing
- Early treatment group, Late treatment group
- Where
- 2 sites in Switzerland
- Volunteers
- 65 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Activity Level
Day Time Activity Level in Inpatient Neurological Rehabilitation as Related to Functional Outcomes at Discharge, Length of Stay, Discharge Location, and Quality of Life: a Preliminary Study
This preliminary study is intended to collect activity level data in a preliminary longitudinal means in order to gain more knowledge into our patient's current activity status.
- Trial name
- NCT04065178
- Testing
- Level of activity
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Intermountain Health Care, Inc.
Stroke, Brain Infarction
Critical Periods After Stroke Study (CPASS)
To perform an exploratory single center randomized study that will form the basis for a larger scale, more definitive randomized clinical trial to determine the optimal time after stroke for intensive motor training.
- Conditions
- Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction
- Trial name
- CPASS (NCT02235974)
- Testing
- Early Intensive upper extremity motor training, Sub-acute intensive upper extremity motor training, Chronic intensive upper extremity motor training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- MedStar National Rehabilitation Network
Parkinson Disease
Predicting Motor Learning of an Upper Limb Task Based on Behavioral and Disease-specific Characteristics in Patients With Parkinson's Disease
Manual dexterity deficits and loss of motor automaticity are commonly seen in patients with Parkinson's disease (PD). Amongst these problems, using a touchscreen is becoming increasingly burdensome.
- Trial name
- NCT06738290
- Testing
- Targeted home-based touchscreen training
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- KU Leuven
Dementia, Mobile Applications
Pilot Study Person-centred Tablet Intervention
First evaluation of FindMyApps, a tablet intervention consisting of a selection tool for usable apps for self-management and meaningful activities and a training that supports informal carers to help people with dementia to learn…
- Conditions
- Dementia, Mobile Applications, Computers, Neurological Rehabilitation
- Trial name
- NCT04026061
- Testing
- FMA group, Control group
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Saxion University of Applied Sciences
Neurological Incidents, Stroke
Affective Responses in Neurological Rehabilitation
Using a single blind within-subject design, 16 patients with neurological disorders were randomly exposed to two different treatments: physical therapy and robotic assisted gait training.
- Conditions
- Neurological Incidents, Stroke, Traumatic Brain Injury
- Trial name
- NCT02767466
- Testing
- Physical therapy and robotic assisted gait training
- Volunteers
- 16 people
- Sponsor
- Universitaet Innsbruck
Stroke
Electrotactile Frequency, Amplitude, and Temporal Gap Discrimination in Young Adults, Older Adults, and Stroke Survivors
The purpose of this study is to evaluate and compare sensory discrimination ability for electrotactile stimulation among young adults, older adults, and patients with stroke.
- Trial name
- ESD-NR (NCT07656675)
- Testing
- Electrotactile Sensory Discrimination Tasks
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sungkyunkwan University
Memory Deficit Aquired Due to the Disease, e.g. Stroke, Neurodegeneration, Inflammatory Disease of CNS, Traumatic Brain Injury
Vestibular Stimulation in Sleep for Neurorehabilitation Patients
1. Why are we conducting this study? You are a patient of the neurorehabilitation clinic with one of the therapy focuses on memory and learning. Neuropsychological training is a standard therapeutic approach in this case.
- Trial name
- NCT07658027
- Testing
- Somnomat - rocking bed providing vestibular stimulation during sleep
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Cereneo AG
Exercise, Sleep
Effects of Exercise and Sleep on Motor Learning and Functional Abilities in Multiple Sclerosis
The ExSiMS study is a randomized, controlled crossover study including 20 individuals (18-70 years) diagnosed with relapsing remitting Multiple Sclerosis (MS) This project investigates, through behavioral and neurophysiological…
- Conditions
- Exercise, Sleep, Motor Learning, Memory
- Trial name
- ExSiMS (NCT07304375)
- Testing
- Aerobic Exercise, Daytime Sleep - Nap
- Where
- 2 sites in Denmark
- Volunteers
- 20 people
- Sponsor
- Zealand University Hospital