Clinical trials: Neurorehabilitation
Stroke, Multiple Sclerosis
Exergames Balance Program in Neurorehabilitation
Exergames are games that require physical movements and are used with a therapeutic purpose, e.g. to improve strength, balance or flexibility.
- Conditions
- Stroke, Multiple Sclerosis, Balance Disorders
- Trial name
- NCT03993275
- Testing
- MindMotion GO
- Where
- Switzerland
- Volunteers
- 84 people
- Sponsor
- Klinik Valens
Parkinson Disease, Occupational Therapy Students
Effect of AI Chatbot-Assisted Versus Traditional Case-Based Learning on Clinical Reasoning in Occupational Therapy Students: A Study on Parkinson's Disease
This study aims to examine whether using an artificial intelligence (AI) chatbot can enhance occupational therapy students' learning during a case-based activity focused on Parkinson's disease.
- Conditions
- Parkinson Disease, Occupational Therapy Students, Clinical Reasoning, Neurologic Rehabilitation
- Trial name
- AI-PD-OT25 (NCT07045077)
- Testing
- AI Chatbot-Assisted Case-Based Learning, Traditional Case-Based Learning with Standard Materials
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ceyhun Türkmen
Parkinson Disease, Pisa Syndrome
TRANSCRANIAL DIRECT CURRENT STIMULATION (t-DCS) AS ADD-ON TO NEUROREHABILITATION OF PISA SYNDROME IN PARKINSON DISEASE
Pisa Syndrome (PS) is a lateral trunk flexion frequently associated to Parkinson's disease (PD). The management of PS is still a challenge for the clinician, because it poorly responds to anti-parkinsonian drugs, and the…
- Trial name
- NCT04620863
- Testing
- t-DCS group
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Spinal Cord Injury, Paraplegia
Effects of Functional Electrical Stimulation on Spasticity, Quadriceps Muscle Strength and Functional Mobility in Individuals With Paraplegia
Spinal cord injury (SCI)-related paraplegia is a complex neurological condition characterized by motor impairment, increased spasticity, and significant functional limitations in daily activities.
- Conditions
- Spinal Cord Injury, Paraplegia, Spasticity, Neurorehabilitation
- Trial name
- FES-PAR-RCT (NCT07583576)
- Testing
- Conventional Neurorehabilitation, Functional Electrical Stimulation (FES) of Quadriceps Muscle
- Sponsor
- Istanbul Medipol University Hospital
Sleep Apnea, Stroke
Non-contact Sleep Apnea Identification in Neurological Rehabilitation
To improve the quality of medical care in the group of poststroke patients, we are planning to examine neurological patients in a rehabilitation clinic simultaneously with a non-contact method (Sleepiz One) and a standard…
- Trial name
- NCT04803552
- Testing
- Overnight sleep study with Sleepiz One and a respiratory polygraphy
- Where
- Switzerland
- Volunteers
- 67 people
- Sponsor
- Sleepiz AG
Cerebrovascular Accident
Wireless Brain-computer-interface-controlled Neurorehabilitation System for Patients With Stroke
This study integrates the wireless EEG system with an ordinary rehabilitation device (an upper limb ergometer, "arm bike") used in the Department of Physical Medicine and Rehabilitation at our hospital for a…
- Trial name
- NCT01880268
- Testing
- BCI-controlled neurorehabilitation device, Standard rehabilitation therapy
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- China Medical University Hospital
Stroke, Neurological Disorder
The Mechatronic Remote Physiotherapy System (MRPS) in Remote Stroke Rehabilitation
The aim of this pilot trial is to examine and compare the safety and feasibility of enhanced Early Supported Discharge (ESD) through the Mechatronic Remote Physiotherapy System (MRPS) and traditional ESD after stroke.
- Trial name
- MRPS (NCT06964789)
- Testing
- Mechatronic Remote Physiotherapy System (MRPS), Early Supported Discharge
- Volunteers
- 14 people
- Sponsor
- Institute of Technology, Sligo
Hand Transplantation, Peripheral Nerve Injuries
Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair
This study adopts a strategy that has arisen from basic neuroscience research on facilitating adaptive brain plasticity and applies this to rehabilitation to improve functional recovery in peripheral nervous system injuries…
- Conditions
- Hand Transplantation, Peripheral Nerve Injuries, Neurologic Rehabilitation
- Trial name
- NCT03610763
- Testing
- Transcranial Direct Current Stimulation, Modified Constraint Induced Movement Therapy
- Where
- 3 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of Missouri-Columbia
Multiple Sclerosis, Stroke
Taxonomy of Neurorehabilitation Treatments and Outcome Measures: a Multicentre Italian Study
The main aims of the observational study are to taxonomize the contents of rehabilitation understanding goals and treatments provided to people with Parkinson Disease(PD) and Multiple Sclerosis(MS) and Stroke and their impact on…
- Conditions
- Multiple Sclerosis, Stroke, Parkinson Disease
- Trial name
- NCT04386863
- Where
- 7 sites in Italy
- Volunteers
- 204 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Multiple Sclerosis, Neurorehabilitation
Neurorehabilitation of Cognitive Deficits in Multiple Sclerosis Using an Adaptive Cognitive Exergame
Approximately 2.8 million people worldwide suffer from multiple sclerosis (MS). In 40 to 70% of cases, individuals with MS experience cognitive impairments that significantly interfere with their personal lives, careers, and…
- Trial name
- REALISE-MS (NCT07086950)
- Testing
- Body Brain Trainer software, RehaCom software
- Where
- Switzerland
- Volunteers
- 190 people
- Sponsor
- Prof. Arseny Sokolov, MD, PhD
Cerebral Palsy, Congenital
CIMT and BIMT Affect Functional Outcome in CP
The aim of this randomized controlled trial is to determine the effects of constraint induced movement therapy CIMT and BIM bimanual activities on functional outcome in hemiplegic CP.
- Trial name
- NCT04211623
- Testing
- Constraint induced movement therapy, Bimanual activities
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Stroke, Spinal Cord Injuries (SCI)
Long-Term Clinical, Health Economic, and Process Evaluation of Intensive Technology-Integrated Motor Rehabilitation in Chronic Neurological Conditions (INTeRAcT-bis)
Rehabilitation remains important in the chronic phase after stroke or spinal cord injury, as meaningful improvements may still be achieved through intensive, goal-directed, and personalized training.
- Conditions
- Stroke, Spinal Cord Injuries (SCI), Chronic Disease
- Trial name
- INTeRAcT-bis (NCT07912320)
- Testing
- Intensive rehabilitation programme
- Where
- 2 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- KU Leuven
Spinal Cord Injuries
Clinical Investigation on Feasibility and Usability of the ABLE Exoskeleton Device for Individuals With Spinal Cord Injury to Perform Skills for Home and Community Environments
The loss of the ability to walk and the associated restriction of mobility presents a major challenge to people with spinal cord injury in an everyday environment designed for pedestrians.
- Trial name
- NCT05643313
- Testing
- ABLE Exoskeleton
- Where
- 2 sites in Germany, Spain
- Volunteers
- 10 people
- Sponsor
- ABLE Human Motion S.L.
Chronic Stroke, Motor Disorders
Immersive Virtual Reality for Stroke Motor Rehabilitation
The present study aims at investigating (i) the feasibility in chronic stroke of using a dedicated virtual reality (VR) based system that embeds real-time 3D motion capture and embodied visual feedback to deliver functional…
- Trial name
- NCT03094650
- Testing
- MindMotion PRO
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Mindmaze SA
Stroke, Stroke Acute
Research on the Effectiveness of Neurorehabilitation After Stroke
This clinical trial aims to investigate the effectiveness of a novel neurorehabilitation technology for treating stroke in adults.
- Conditions
- Stroke, Stroke Acute, Stroke with Hemiparesis, Stroke, Acute
- Trial name
- NCT06753006
- Testing
- Neurorehabilitation simulator, Standard course
- Where
- Russia
- Volunteers
- 44 people
- Sponsor
- Neurotechnika
Movement Disorders, Neurorehabilitation
Towards Restoring Complex Movement After Paralysis: Algorithm Development With Healthy Participants
Participants will perform experiments with non-invasive activity recordings. The study will record from multiple non-invasive signal sources that reflect motor intent that may include: electroencephalography (EEG)…
- Conditions
- Movement Disorders, Neurorehabilitation, Non-invasive Activity Recording
- Trial name
- NCT07236892
- Testing
- Participants will perform experimental tasks while undergoing non-invasive activity recordings, which may include EEG, EMG, IMUs, fNIRS, eye gaze, or pupillometry.
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Stroke
Control of Degrees of Freedom Post-stroke for the Recovery of the Upper Limb
The study's methodology will be a single-blind, multicenter, parallel-group randomized controlled trial (RCT). The sample consists of stroke patients (supratentorial ischemic and hemorrhagic stroke of anterior territory) between…
- Trial name
- DoF_UL_S (NCT05371444)
- Testing
- Training with restriction of the DoF, Training without restriction of the DoF
- Where
- Chile
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Chile
Post-stroke Cognitive Impairment
Noninvasive Dual-mode Stimulation Therapy for Neurorehabilitation in Post-stroke Cognitive Impairment
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of post-stroke cognitive impairment patients' cognitive function by altering the cortical…
- Trial name
- NCT03647319
- Testing
- High-frequency rTMS on left DLPFC+anodal tDCS on right DLPFC, High-frequency rTMS on left DLPFC+cathodal tDCS on right DLPFC
- Where
- South Korea
- Volunteers
- 29 people
- Sponsor
- Samsung Medical Center
Stroke
Precision Sensorimotor Neurorehabilitation Through Personalized Stimulation Loops
Stroke is the most common neurological disease in the elderly population and accounts for substantial disability and health care costs. Disability is largely driven by mobility deficits caused by impaired gait.
- Trial name
- StimuLOOP-S (NCT06466772)
- Testing
- Hyper-personalized feedback (HPF intervention), Targeted auditory stimulation during sleep (TASS verum intervention)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Stroke, Ischemic, Stroke
Validation of a Brain-Computer Interface for Stroke Neurological Upper Limb Rehabilitation
The study's main goal is to determine if clinical and physiological effects of a brain-computer interface intervention for the neurorehabilitation of stroke patients' upper limb are greater than the effects of a sham robotic…
- Trial name
- NCT04724824
- Testing
- Brain-Computer Interface
- Where
- Mexico
- Volunteers
- 23 people
- Sponsor
- Instituto Nacional de Rehabilitacion