Clinical trials: Neurorehabilitation
Rehabilitation, Balance
Peripheral Neuropathy Rehabilitation With Stabilometric Platforms (NEUROSTAB)
The goal of this clinical trial is to learn if the GeaMaster stabilometric platform can support rehabilitation and improve balance and walking ability in adults diagnosed with peripheral neuropathy.
- Trial name
- NEUROSTAB (NCT07029620)
- Testing
- Balance and postural rehabilitation using sensor-based stabilometric platform (GEAMASTER) under static and dynamic conditions, Conventional balance and gait rehabilitation program, Stabilometric assessment in healthy volunteers
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ospedale Policlinico San Martino
Parkinson's Disease
At-home taVNS for Neurorehabilitation in Parkinson's Disease
The goal of this clinical trial is to learn if taVNS works to treat symptoms of Parkinson's Disease in adults. It will also learn about the feasibility and preliminary efficacy of taVNS administered at home by the participant.
- Trial name
- NCT07536022
- Testing
- transcutaneous auricular nerve stimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Medical University of South Carolina
Stroke, Hemiparesis
RGS@Home: Personalized 24/7 Home Care Post-stroke
Stroke represents one of the main causes of adult disability and will be one of the main contributors to the burden of disease in 2030.
- Conditions
- Stroke, Hemiparesis, Subacute Stroke, Chronic Stroke
- Trial name
- NCT04620707
- Testing
- RGS based training and monitoring, Therapy as usual
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Institute for Bioengineering of Catalonia
Stroke
Generalizability of Unsupervised Therapy After Stroke in the Home Setting With a Hand Rehabilitation Device (ReHandyBot)
The ReHandyBot (RHB) is a robot for hand rehabilitation after stroke. The aims of this study are to investigate (i) the generalizability of unsupervised therapy with the ReHandyBot within patients' home after discharge from a…
- Trial name
- RHB Home SNR (NCT07674238)
- Testing
- Supervised and minimally supervised therapy with ReHandyBot, Unsupervised therapy
- Where
- 4 sites in Switzerland
- Volunteers
- 40 people
- Sponsor
- Swiss Federal Institute of Technology
Cerebrovascular Accident
Neural Mechanisms and Efficacy of Dual Neurotechnology-aided Mirror Therapy in Chronic Stroke: Neural and Motor Plasticity, Movement Performance, Daily Function, and Quality of Life
Mirror therapy (MT) has been demonstrated, in terms of neuroplasticity, to improve sensorimotor function of paretic upper extremity (UE) in chronic stroke patients.
- Trial name
- NCT04326205
- Testing
- transcranial direct current stimulation, tDCS, functional electrical stimulation, FES, no stimulation
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- Chang Gung Memorial Hospital
Cerebral Palsy
Effects of Lokomat-Robot Assisted Gait Training on Gross Motor Function in Children and Young Adults With Cerebral Palsy
This single-center, controlled, delayed-intervention, quasi-experimental study evaluates the effectiveness of Lokomat®-assisted robotic gait training on gross motor function and health-related quality of life in children and…
- Trial name
- NCT07732205
- Testing
- Sessions with Lokomat robot-assisted system, Control arm
- Where
- Hungary
- Volunteers
- 96 people
- Sponsor
- Semmelweis University
Neurological Diseases or Conditions, Cardiovascular Diseases
New Technological Pathway for Gait Rehabilitation
Brief Summary The study aims to explore how the integration of visual and motor systems can be trained and enhanced to improve gait rehabilitation in patients with various neurological and cardiovascular conditions.
- Conditions
- Neurological Diseases or Conditions, Cardiovascular Diseases, Neuromuscular Disease
- Trial name
- LABODIMOTO (NCT06859229)
- Testing
- Innovative technology pathway for gait neurorehabilitation, Conventional gait rehabilitation strategy
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Stroke, Neurorehabilitation
Theta-Burst-Stimulation in Recurrent Stroke Recovery
The present study aims at investigating the effects of intermittent theta-burst stimulation (iTBS) for motor recovery in recurrent stroke patients.
- Trial name
- NCT03337867
- Testing
- Magstim Super Rapid2 System
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital of Cologne
Stroke
Noninvasive Dual-mode Stimulation Therapy for Neurorehabilitation in Stroke
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of stroke patients' motor function by altering the cortical excitability.
- Trial name
- NCT03390192
- Testing
- Dual-mode stimulation
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Samsung Medical Center
Neuro-Degenerative Diseases, Care Givers
Informational Needs of Caregivers of Patients With Neuromotor Disease in Rehabilitation Hospitalization: Validation Study of the QBI-R/V
Background and rationale. Although the literature suggests that caregivers have different needs at various stages of the patient's illness, to date, most studies have focused only on the needs of caregivers of patients with…
- Conditions
- Neuro-Degenerative Diseases, Care Givers, Ictus, Brain Injury
- Trial name
- NCT07903298
- Testing
- QBI questionnaires
- Where
- 13 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Neuralgia, Spinal Cord Injuries
Immersive Virtual Reality for Chronic Neuropathic Pain After Spinal Cord Injury: A Feasibility Trial
The aim of this study is to provide critical information about the efficacy of Immersive Virtual Reality (IVR) to decrease the experience of neuropathic pain in the upper and lower extremities of people with a spinal cord injury.
- Conditions
- Neuralgia, Spinal Cord Injuries, Chronic Pain
- Trial name
- NCT04700033
- Testing
- Somatic IVR (sIVR), Distractive IVR (dIVR), Control IVR (cIVR)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Stroke
Neurorehabilitation With Mindlenses in Stroke Patients
This study aims to describe the use of MindLenses, a rehabilitation device that integrates prism adaptation with serious game-based cognitive exercises, in individuals undergoing cognitive rehabilitation after stroke.
- Trial name
- NCT07322614
- Testing
- MindLenses Cognitive Training
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Ataxia - Other
Robotic Neurorehabilitation in Patients With Ataxia
This interventional study evaluates the effectiveness of robot-assisted neurorehabilitation in patients with ataxia. Participants will receive a structured robotic neurorehabilitation treatment program, and changes in motor…
- Trial name
- NCT07733687
- Testing
- Robot-Assisted Neurorehabilitation, Conventional Neurorehabilitation
- Where
- Hungary
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Somogy Megyei Kaposi Mór Teaching Hospital
Stroke
taVNS for Upper Limb Rehabilitation
This study explores the use of a new form of neuromodulation known as transcutaneous auricular vagus nerve stimulation (taVNS) which stimulates the ear.
- Trial name
- NCT04129242
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) + Task Specifc Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Stroke, Cerebrovascular Accident
Cardiac Rehabilitation of Stroke Survivors (SRP-CROSS)
This study examines the effectiveness of the cardiac rehabilitation program for stroke patients. The study will examine if patients with stroke, who receive cardiac rehabilitation in addition to their standard of care treatments…
- Trial name
- SRP-CROSS (NCT05651945)
- Testing
- Cardiac rehabilitation program
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Hackensack Meridian Health
Multiple Sclerosis
Comprehensive Rehabilitation Programme in People With Multiple Sclerosis: The RECONNECT-MS Study
The goal of this clinical trial is to learn if a comprehensive rehabilitation programme can improve physical function, reduce fatigue, and raise quality of life in adults aged 18-65 with multiple sclerosis (MS).
- Trial name
- RECONNECT-MS (NCT07666958)
- Testing
- Individual Physiotherapy, Group Movement Awareness, Group Psychotherapy
- Where
- Czechia
- Volunteers
- 45 people
- Sponsor
- Charles University, Czech Republic
Glioma, Glioma, Malignant
Personalized Rendering of Motor System Functional Plasticity Potential to Improve Glioma Resection and Quality of Life
Background Lower-grade-gliomas affect young patients, thus the longest progression-free-survival (PFS) with a high level quality of life is crucial.
- Trial name
- NCT06381726
- Testing
- Resting State Functional Magnetic Resonance Imaging (rs-fMRI), Up-front Motor Rehabilitation, Up-front Chemotherapy
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- University of Milan
Mild Cognitive Impairment (MCI), AMCI - Amnestic Mild Cognitive Impairment
Effects of Combined Aerobic and Cognitive Training in a Simultaneous or Sequential Paradigm on Cognition and Brain Functional Activity in Patients with AMCI
Mild Cognitive Impairment (MCI) is a condition in which patients show an objective evidence of impairment in one or more cognitive domains but a spared independence in daily functional abilities.
- Conditions
- Mild Cognitive Impairment (MCI), AMCI - Amnestic Mild Cognitive Impairment, Neurodegenerative Dementia, Neurodegenerative Disease
- Trial name
- NCT06755164
- Testing
- Simultaneous aerobic and cognitive training (SIM), Sequential aerobic and cognitive training (SEQ)
- Where
- Italy
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Stroke, Paresis
Evidence-Based Robot-Assistant in Neurorehabilitation
The purpose of this study is to investigate the efficacy, acceptability, and safety of the therapeutic system E-BRAiN for the treatment of stroke-related impairments.
- Conditions
- Stroke, Paresis, Neglect, Hemispatial
- Trial name
- E-BRAiN (NCT05152433)
- Testing
- E-BRAiN therapy, Conventional therapy
- Where
- 2 sites in Germany
- Volunteers
- 40 people
- Sponsor
- University Medicine Greifswald
Chronic Stroke
Brain Stimulation and Robotics in Chronic Stroke Motor Recovery
Motor skill training and transcranial direct current stimulation (tDCS) have separately been shown to alter cortical excitability and enhance motor function in humans.
- Trial name
- NCT03562663
- Testing
- Transcranial direct current stimulation, Upper extremity robotics
- Volunteers
- 82 people
- Sponsor
- Burke Medical Research Institute