Clinical trials: Neutrophil-Lymphocyte Ratio
Idiopathic Parkinson's Disease
Comparison of Balance, Activity-specific Balance Confidence and Quality of Life in Parkinson's Patients
Parkinson's disease is characterized by cardinal motor signs and motor freezing, gait, posture and balance disorder. About 80% of the causes of falls in Parkinson's patients are due to postural instability and motor freezing, and…
- Trial name
- NCT05671341
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Nigde Omer Halisdemir University
Chronic Kidney Diseases, Dialysis; Complications
Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio to Predict Carotid Intima-Media Thickness in Chronic Kidney Disease Patients
This study aims to determine whether the neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) can be used as predictors of coronary heart disease (CHD) in CKD patients undergoing dialysis at Moewardi General…
- Conditions
- Chronic Kidney Diseases, Dialysis; Complications, Coronary Heart Disease
- Trial name
- NCT05472805
- Where
- Indonesia
- Volunteers
- 72 people
- Sponsor
- Universitas Sebelas Maret
Pancreatic Cancer, Adult, Perineural Invasion
Neutrophil-to-lymphocyte Ratio and CA 19.9 as Predictors of Perineural Invasion in Pancreatic Cancer
Pancreatic cancer has an incidence of 1,401,450 new cases diagnosed annually worldwide and is the third leading cause of cancer-related death in Spain.
- Conditions
- Pancreatic Cancer, Adult, Perineural Invasion, Neutrophil-to-Lymphocyte Ratio, CA 19.9
- Trial name
- NCT06747481
- Where
- Spain
- Volunteers
- 323 people
- Sponsor
- University of Las Palmas de Gran Canaria
Carcinoma, Squamous Cell of Head and Neck HNSCC
Safety and Efficacy of Ruxolitinib in Patients With HNSCC and High NLR Treated With Pembrolizumab - The Phase 2 InflammaSTOP Trial
The goal of this Phase 2 clinical trial is to learn if adding ruxolitinib to pembrolizumab may improve treatment outcomes in patients with head and neck squamous cell carcinoma (HNSCC) who have increased levels of systemic…
- Trial name
- InflammaSTOP (NCT07840456)
- Testing
- Ruxolitinib, Pembrolizumab
- Where
- 10 sites in Germany, Switzerland
- Volunteers
- 66 people
- Sponsor
- University Hospital, Basel, Switzerland
Burns, Physiotherapy
The Effect of Aerobic Exercise on Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio and Lymphocyte-Monocyte Ratio in Burn Patients: A Randomized Controlled Study
In the study, it was planned to investigate the Effect on Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio and Lymphocyte-Monocyte Ratio in burn patients by creating 2 different exercise groups.
- Conditions
- Burns, Physiotherapy, Aerobic Exercises
- Trial name
- NCT06013553
- Testing
- Control Group, Aerobic Exercises group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hasan Kalyoncu University
Hemodialysis Complication
Impact of Neutrophil Lymphocyte and Monocyte Lymphocyte Ratio on Chronic Kidney Disease Patients Outcome
The aim of this study is to establish NLR, MLR as a good predictors for outcome of CKD including hemodialysis and CKD stage (4-5) patients as regard inflammation, malnutrition and anemia on cardiovascular complication.
- Trial name
- NCT05887960
- Testing
- CBC and flow cytometry test for monocyte
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hypertension in Pregnancy
Effect of Hydroxytyrosol on NLR, MLR, and SOD in Hypertensive Pregnant Women
The goal of this clinical trial is to evaluate whether hydroxytyrosol supplementation (10 mg/day for 4 weeks) is effective in improving inflammatory and oxidative stress markers in pregnant women diagnosed with hypertensive…
- Trial name
- HyPreg (NCT07074548)
- Testing
- Hydroxytyrosol
- Where
- Indonesia
- Volunteers
- 42 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Effusion
Neutrophil-to Lymphocyte and Monocyte-to-Lymphocyte Ratios in Exudative Pleural Effusion
Exudative pleural effusion (EPE) presents a diagnostic challenge, requiring accurate biomarkers to predict outcomes and guide treatment.
- Trial name
- NCT07003204
- Testing
- medical thoracoscopy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Acute Pancreatitis, Pancreatitis
CBC-Derived Inflammatory Indices in Acute Pancreatitis
This prospective observational study aims to evaluate the prognostic value of complete blood count (CBC)-derived inflammatory indices, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and…
- Trial name
- NCT07793734
- Volunteers
- 109 people
- Sponsor
- Assiut University
ST Elevated Myocardial Infarction
Neutrophil/Lymphocyte (N/L) Ratio and Long Term Follow-up in ST-elevation Myocardial Infarction
Although the pre-procedural neutrophil to lymphocyte ratio (N/L) has been associated with adverse outcomes among patients with coronary artery disease, its role during the acute phase of ST-segment elevation myocardial infarction…
- Trial name
- NCT01663194
- Testing
- primary percutaneous coronary intervention, each groups
- Where
- Turkey (Türkiye)
- Volunteers
- 1,034 people
- Sponsor
- TC Erciyes University
Breast Cancer Female
Does Type of Anesthesia Influence Inflammation Change After Breast Surgery?
The Neutrophil to Lymphocyte Ratio (NLR) is a frequently used biomarker of the systemic inflammatory response and is considered one of the most sensitive markers of inflammation.
- Trial name
- NCT04172220
- Testing
- Midazolam, PECS, Opioid-free general anesthesia
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- Centro di Riferimento Oncologico - Aviano
Polypharmacy
Risk Factors for Polypharmacy in Older Adults
Patients who were 65 years old or older and applied to Melek Hatun family practice center were enrolled in the study. All patients were seen either in our center or in their homes, and informed consents were obtained.
- Trial name
- NCT03524560
- Testing
- Comprehensive geriatric assesment
- Volunteers
- 1,000 people
- Sponsor
- Karabuk University
Spontaneous Bacterial Peritonitis
MPV and NLR as Predictors of SBP Diagnosis
The aim of the study is to investigate the clinical utility of mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) as diagnostic markers for spontaneous bacterial peritonitis (SBP).
- Trial name
- NCT04775420
- Testing
- Measurement of mean platelet volume (MPV) and blood neutrophil to lymphocyte ratio (NLR)
- Where
- Egypt
- Volunteers
- 332 people
- Sponsor
- Sohag University
Burnout Syndrome, Neutrophil-Lymphocyte Ratio
Music Therapy on Neutrophyl Lymphocytes Ratio, Interleukin 6 and Interleukin 10 Levels of Burnout Syndrome
Burnout Syndrome (BOS) can be defined as a state of stress both physically and psychically due to the burden and stressor of high work. The prevalence of BOS in health workers varies between 25-75% globally.
- Conditions
- Burnout Syndrome, Neutrophil-Lymphocyte Ratio, Interleukin-6, Interleukin-10
- Trial name
- NCT05750160
- Testing
- music therapy
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
İntensive Care Unit
ICU Mortality Predictors of Trauma Patients
In this study, the data of the patients who were hospitalized due to trauma in intensive care unit (ICU) were examined in their first development.
- Trial name
- NCT03894111
- Testing
- decesased patients
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Balikesir University
Laparoscopic Hysterectomy, Abdominal Hysterectomy
Pentraxin-3 in Hysterectomy Patients
Comparison of the Tissue Trauma Markers Following Total Laparoscopic Hysterectomy vs Total Abdominal Hysterectomy
- Trial name
- NCT04366375
- Testing
- PTX-3
- Volunteers
- 40 people
- Sponsor
- Muğla Sıtkı Koçman University
Ventilator Associated Pneumonia
Prognostic Biomarkers in Predicting Mortality in Respiratory Patients With Ventilator-Associated Pneumonia
The aim of this study is to evaluate prognostic efficiency RDW and NLR for mortality prediction in respiratory patients with VAP.
- Trial name
- NCT04739748
- Testing
- complete blood picture
- Where
- Egypt
- Volunteers
- 136 people
- Sponsor
- Assiut University
Insulin Resistance, Cardiac Surgery Requiring Cardiopulmonary Bypass
Relation Between Insulinoresistance and Neutrophile to Lymphocyte Ratio in Cardiac Surgery.
The University Hospital of Besançon is conducting a public interest research project called CRYSTAL, who studies the relationship between the Neutrophil to Lymphocyte ratio (NLR) and insulin resistance in post-operative cardiac…
- Conditions
- Insulin Resistance, Cardiac Surgery Requiring Cardiopulmonary Bypass, Neutrophil Lymphocyte Ratio
- Trial name
- CRYSTAL (NCT06945536)
- Where
- France
- Volunteers
- 211 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Sepsis
N\L Ratio Versus L\A Ratio as a Predictor of Morbidity and Mortality in Sepsis and Septic Shock
The aim of the study is to compare between neutrophil lymphocyte ratio and lactate albumin ratio as a predictor of morbidity and mortality in sepsis and septic shock patients.
- Trial name
- NCT05825118
- Testing
- Neutrophil/Lymphocyte ratio and lactate/ albumin ratio will be measured in all patients.
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Ventilator-associated Pneumonia (VAP)
Use of Reticulocyte Ratio and Neutrophil / Lymphocyte Ratio in the Diagnosis of Ventilator-associated Pneumonia
In this study, the utility of changes in the ratio of Ret-He and NLR as an early inflammation marker for VAP will be evaluated.
- Trial name
- NCT04620941
- Testing
- reticulocyte/hemoglobin (Ret-He) ratio
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Muğla Sıtkı Koçman University