Clinical trials: Newborn Health
Pregnancy, Fetal and Neonatal Health
Outcome of Fetal Spina Bifida
Neural tube defects are one of the most prevalent congenital abnormalities, surpassed only by cardiac malformations. Spina bifida accounts for the majority of the neural tube defects and is comprised of a wide spectrum of…
- Trial name
- NCT01100697
- Where
- Germany
- Volunteers
- 103 people
- Sponsor
- University of Luebeck
Sepsis, Umbilical Cord
Perinatal Handwashing Intervention in Bangladesh
The purpose of this study is to determine if an intensive handwashing intervention administered to primiparous women during their pregnancy can increase maternal handwashing with soap at critical times.
- Conditions
- Sepsis, Umbilical Cord, Infection
- Trial name
- NCT01309321
- Testing
- Perinatal Handwashing Promotion, Neonatal Health Promotion
- Where
- Bangladesh
- Volunteers
- 400 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Congenital Heart Disease
Design and Application of a Home Care WeChat Mini-Program for Children After Congenital Heart Disease Surgery
This is a single-blind, randomized controlled trial aimed at evaluating the effectiveness of a family-centered, WeChat-based home care mini-program for children after congenital heart disease (CHD) surgery.
- Trial name
- CHD-HomeCare (NCT07385209)
- Testing
- Home Care WeChat Mini-Program, Routine Care with Telephone Follow-up
- Where
- China
- Volunteers
- 210 people
- Sponsor
- ruijie YangLan
Executive Dysfunction, Cognitive Deficits
Cognitive Rehabilitation in Patients With Spina Bifida
This study will examine the effects of a theoretically grounded and manualized cognitive rehabilitation program on patients with Spina Bifida (SB).
- Conditions
- Executive Dysfunction, Cognitive Deficits, Spina Bifida
- Trial name
- NCT01302314
- Testing
- Goal management training (GMT)
- Where
- Norway
- Volunteers
- 38 people
- Sponsor
- Jan Stubberud
Infant, Premature, Infant, Low Birth Weight
Global Survey on Newborns' HOspitalisation and Parental Experiences - the HOPE Study
This study aims to explore parents' experiences and emotional burdens related to their newborn's hospital stay using an online survey.
- Conditions
- Infant, Premature, Infant, Low Birth Weight, Parents, Life Change Events
- Trial name
- HOPE (NCT06827028)
- Testing
- N/A, no intervention, participation in survey
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Global Foundation for the Care of Newborn Infants
Ventilator Associated Pneumonia, Bronchopulmonary Dysplasia
Frequent Standardized Oral Care Using Human Milk in the Neonatal Intensive Care Unit
Premature infants are susceptible to complications related to infrequent and non-standardized oral care. Although the benefits of frequent standardized oral care are known to reduce oral dysbiosis (increased level of potentially…
- Conditions
- Ventilator Associated Pneumonia, Bronchopulmonary Dysplasia, Respiratory Disease
- Trial name
- NCT06000761
- Testing
- Standardized oral Care
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- University of Florida
Home Monitoring, Congenital Heart Disease
Cardiac Acute Transitioning Care to Home (CATCH) App Data Repository
This repository will consist of clinically derived data and images of patients with congenital heart disease from the time of birth until they have reached one of the following outcomes: transition to outpatient care that has not…
- Conditions
- Home Monitoring, Congenital Heart Disease, Mobile Health
- Trial name
- CATCH (NCT04498728)
- Testing
- Mobile Health Application for Remote Monitoring
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Children's Mercy Hospital Kansas City
COVID-19, Pregnancy Outcomes
Impact of COVID-19 on Pregnancy Outcomes: a Systematic Review
This systematic review aims to evaluate the impact of COVID-19 on pregnancy outcomes. It synthesizes data from various studies to provide insights into the effects of the virus on maternal and fetal health.
- Conditions
- COVID-19, Pregnancy Outcomes, Maternal Health, Neonatal Health
- Trial name
- COVID-PREG (NCT06677281)
- Testing
- Systematic Review of COVID-19's Impact on Pregnancy Outcomes
- Where
- Iran
- Volunteers
- 1 people
- Sponsor
- Zahedan University of Medical Sciences
Alopecia Areata, Depressive Episode
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
This study series consists of four related studies and aims to explore and describe many important elements of alopecia areata over three key areas: (1) the current epidemiology of alopecia areata, (2) the prevalence and…
- Conditions
- Alopecia Areata, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04239521
- Testing
- Exposure of interest (studies 2 & 3).
- Where
- United Kingdom
- Volunteers
- 51,955 people
- Sponsor
- Momentum Data
Metabolic Bone Disease, Osteopenia
A Study to Assess Metabolic Bone Disease of Prematurity Using an Acoustic Method
The goal of this project is to develop a new noninvasive ultrasound based technique, called vibro-acoustic analysis (VAA), for evaluation of infant bone health with particular application in assessment of bone health in premature…
- Conditions
- Metabolic Bone Disease, Osteopenia, Neonatal Rickets
- Trial name
- NCT04752098
- Testing
- Vibro-acoustic analysis (VAA), based on ultrasound radiation force
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Mayo Clinic
PCOS, Offspring, Adult
Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort Study
The Offspring Born to Mothers with Polycystic Ovary Syndrome in Guangzhou Cohort study (PCOS-BIG) was established to investigate the short- and long-term effects of intrauterine exposure to maternal PCOS on the health of…
- Conditions
- PCOS, Offspring, Adult, Hyperandrogenism, Epigenetics
- Trial name
- PCOS-BIG (NCT03742011)
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Haemophilia
Virtual Evaluations of Joint Health Using Wearable Sensors in Persons With Haemophilia (VESPA)
Recent technological innovations have enabled the creation of portable and easy-to-wear sensors with incredible potential to alter the clinical practice of rehabilitation.
- Trial name
- VESPA (NCT06046235)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Chronic Kidney Diseases, Diabetes
KidneYou - Innovative Digital Therapy
The aim of the study is to assess the improvement of health in patients affected by CKD when they are exposed to non-pharmacological treatment strategies as nutritional program (NP), physical activity program (PA) and mindfulness…
- Conditions
- Chronic Kidney Diseases, Diabetes, Arterial Hypertension, Chronic Glomerulonephritis
- Trial name
- NCT05286632
- Testing
- KidneYou APP
- Where
- Italy
- Volunteers
- 210 people
- Sponsor
- Advice Pharma Group srl
Down Syndrome, Trisomy 21
Down Syndrome Metabolic Health Study
The purpose of this research study is to determine which measures best capture cardiovascular disease (CVD) risk and type 2 diabetes (T2DM) risk in children and adolescents with Down syndrome (DS).
- Trial name
- NCT01821300
- Where
- 2 sites in United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Neonatal Death, Perinatal Death
Leveraging Interactive Text Messaging to Monitor and Support Maternal Health in Kenya
Mobile health (mHealth) interventions such as interactive short message service (SMS) text messaging with healthcare workers (HCWs) have been proposed as efficient, accessible additions to traditional health care in…
- Conditions
- Neonatal Death, Perinatal Death, Depression
- Trial name
- AI-NEO (NCT05369806)
- Testing
- Interactive two-way SMS dialogue
- Where
- 2 sites in Kenya
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Preterm Birth
Multiperfusion Neonatal System
Infusion and parenteral nutrition play an important role in the management of neonatal intensive care patients. Administration of drugs and parenteral nutrition solutions to the patient is performed via different systems…
- Trial name
- EDELWEISS (NCT05058534)
- Testing
- Multiline Neo®
- Where
- France
- Volunteers
- 640 people
- Sponsor
- Hospices Civils de Lyon
Gestational Diabetes Mellitus
Study of Pregnancy And Neonatal Health (SPAN)
This study will conduct a randomized trial among women with gestational diabetes (GDM). Study of Pregnancy And Neonatal health (SPAN), TIMing of dElivery (TIME) is a randomized trial that will recruit up to 3,450 pregnant women…
- Trial name
- SPAN (NCT05515744)
- Testing
- Childbirth
- Where
- 8 sites in United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hemophilia A
Joint Health, Balance and Quality of Life in Adults With Hemophilia A
Hemophilia is a hereditary bleeding disorder characterized by recurrent bleeding episodes, particularly into joints and muscles, leading to chronic musculoskeletal complications.
- Trial name
- NCT07523399
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Yuzuncu Yil University
Turner Syndrome, Turner Syndrome Mosaicism, 45, X/46, XX or XY
Health, Fitness, and Quality of Life in Adolescent Girls With Turner Syndrome
This study plans to learn more about how the energy system works in girls with Turner syndrome. This is important to know so that the investigators understand how Turner syndrome relates to diseases such as diabetes, extra weight…
- Conditions
- Turner Syndrome, Turner Syndrome Mosaicism, 45, X/46, XX or XY, Turner Syndrome Mosaicism 46,X,I(X)(Q10)/45,X, Turner Syndrome Karyotype 46,X With Abnormal Sex Chromosome , Except I(Xq)
- Trial name
- NCT03181230
- Testing
- No intervention
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Colorado, Denver
Anemia, Low Birth Weight
Treatment and Prevention of Severe Anemia in Pregnant Zanzibari Women
The purpose of this research is to compare the efficacy of two low-cost low intervention packages to prevent and treat severe anemia in pregnant women in Zanzibar, Tanzania.
- Conditions
- Anemia, Low Birth Weight, Neonatal Mortality
- Trial name
- NCT00148629
- Testing
- multivitamin, mebendazole
- Where
- Tanzania
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Cornell University
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