Clinical trials: Newborn Resuscitation
Hypothermia, Newborn
Evaluate the Use of Plastic Bags in Preventing and Treating Hypothermia in Neonates
The overall hypothesis is that placing infants 1000-2500 grams in plastic bags when compared to routine care will reduce the risk of hypothermia (< 36.5 degrees C) without increasing hyperthermia (> 37.5 degrees C).
- Trial name
- NCT01403623
- Testing
- Resuscitation and post resuscitation care with plastic bag, Resuscitation- no plastic bag for temperature regulation
- Where
- Zambia
- Volunteers
- 106 people
- Sponsor
- University of Alabama at Birmingham
Prematurity
Electrocardiography Versus Pulse Oximetry for Newborn Heart Rate Determination
The goal of this study is to compare the time required for accurate heart rate measurement of the preterm newborn when using pulse oximetry versus electrocardiography leads.
- Trial name
- NCT01256346
- Testing
- Apparatuses
- Where
- United States
- Sponsor
- University of Oklahoma
Neonatal Resuscitation
Non-inflatable Supraglottic Airway (NI-SGA) vs. Face Mask (FM) as a Primary Interface Device for Neonatal Resuscitation
Prospective, randomized controlled trial to be performed at one center, of term and late preterm infants requiring resuscitation. Prenatal consent will be obtained.
- Trial name
- NCT02629887
- Testing
- Non-inflatable supraglottic airway, Face Mask, T-Piece Resuscitator
- Where
- United States
- Sponsor
- University of Oklahoma
Respiratory Distress
Efficacy and Safety of Gastric Suctioning During Neonatal Resuscitation
The stomach of the newborn baby is often emptied soon after birth to prevent breathing problems (respiratory distress). Babies born with meconium-stained amniotic fluid and those with increased secretions associated with birth by…
- Trial name
- NCT00729989
- Testing
- Gastric suctioning
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Benjamin T. Stevens
Infant Showing No Response to Resuscitation
MedNav: Improving Neonatal Life Support (NLS)
This study was designed to evaluate if MedNav impacts the ability of novice resuscitators to perform Neonatal Life Support (NLS) in the simulated environment, and if this ability is maintained after a 7 week period.
- Trial name
- NCT02932683
- Testing
- MedNav
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Congenital Diaphragmatic Hernia
Initiation of Resuscitation While Attached to the Cord With Congenital Diaphragmatic Hernia
This study aims to measure the cardio-respiratory physiological consequences of initiating resuscitation during placental transfusion (PT) with an intact umbilical cord in infants with congenital diaphragmatic hernia (CDH).
- Trial name
- INSPIRE-CDH (NCT03094039)
- Testing
- Ventilatory support while attached to the cord, Immediate cord clamping
- Where
- Canada
- Sponsor
- University of Alberta
Premature Birth
Prophylactic DR-CPAP on Late Preterm Infants Born by C-section: an RCT
A Pragmatic Randomized Controlled Pilot Trial to Evaluate the Impact of Early Prophylactic Continuous Positive Airway Pressure with or without Supplemental Oxygen in Spontaneously Breathing Late Preterm Newborn Infants Born by…
- Trial name
- PLANT (NCT05204719)
- Testing
- Prophylactic Delivery Room Continuous Positive Airway Pressure
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Preterm, General Movements
Fidgety Movements of Preterm Neonates Included in COSGOD III
The evidence on the effects of clinical care with cerebral NIRS (Near-infrared spectroscopy) monitoring on short term neurological outcome, displayed by fidgety movements between six to 20 weeks post term, are still uncertain.
- Conditions
- Preterm, General Movements, Fidgety Movements, Near Infrared Spectroscopy
- Trial name
- Figdety_Ms (NCT06105333)
- Testing
- standard care plus cerebral oxygen saturation monitoring with a dedicated treatment guideline
- Where
- 2 sites in Austria
- Volunteers
- 183 people
- Sponsor
- Medical University of Graz
Hypothermia, Immature Newborn
Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part I
The overall hypothesis is that plastic bags used in combination with WHO thermoregulation care will reduce the incidence of hypothermia in preterm/low birth weight and full term infants when compared to routine WHO…
- Trial name
- NCT01604317
- Testing
- Resuscitation-torso plastic bag, Resuscitation-partial-head plastic bag
- Where
- Zambia
- Volunteers
- 182 people
- Sponsor
- University of Alabama at Birmingham
Neonatal Resuscitation, Clinical Competence
POV Video and Mental Practice Training for Neonatal LMA Insertion
This prospective, randomized, single-blind simulation study aims to evaluate and compare the educational efficacy of a hybrid instructional modality-combining point-of-view (POV) video training and structured mental practice…
- Conditions
- Neonatal Resuscitation, Clinical Competence, Simulation Training, Airway Management
- Trial name
- NCT07678424
- Testing
- Standard Instructor Demonstration, POV Video and Mental Practice
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Pregnancy
The Effect of SCIM on Neonatal Resuscitation
In this randomized controlled trial 48 students were randomly allocated in three groups SCIM, Video training (VT) and control group(no training). They had a workshops based on NRP and lasted 6 hours for each group.
- Trial name
- NCT02082964
- Testing
- SCIM, video
- Where
- Iran
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Premature Birth
Order Effects of Prematurity Outcome Data
Women recruited from the internet were put in a hypothetical situation of being in labor at 22 weeks of pregnancy, and presented with information in the form of pictographs about survival and disability of babies born at this…
- Trial name
- NCT04269616
- Testing
- Order of pictographs provided to participants, Level of description in survival pictograph
- Where
- United States
- Volunteers
- 839 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Neonatal Resuscitation
Supreme-LMA for Neonatal Resuscitation: a Prospective, Randomized Single-center Study
Laryngeal mask airways (LMA) that fit over the laryngeal inlet have been shown to be effective for ventilating newborns at birth.
- Trial name
- NCT01963936
- Testing
- Supreme LMA, Facial mask
- Where
- Vietnam
- Volunteers
- 142 people
- Sponsor
- University of Padova
Neurologic Manifestations, Premature Birth
The Neu-Prem Trial: Neuromonitoring of Preterm Newborn Brain During Birth Resuscitation
The purpose of this study is to characterize the normal brain function of premature infants (23 to 31+6 weeks GA) during birth transition and through the first 72 hours of life.
- Conditions
- Neurologic Manifestations, Premature Birth, Hypoxia-Ischemia, Brain
- Trial name
- Neu-Prem (NCT02605733)
- Testing
- EEG, NIRS
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Sharp HealthCare
Preterm Birth, Extreme Prematurity
Sustained Aeration of Infant Lungs Trial
This study is a 2-arm randomized, controlled, multi-center clinical trial to determine which of two strategies at birth are best to optimally aerate the lung of preterm infants.
- Trial name
- SAIL (NCT02139800)
- Testing
- Sustained Inflation, Standard of Care
- Where
- 21 sites in United States, Australia and 7 more
- Volunteers
- 460 people
- Sponsor
- University of Pennsylvania
Pregnancy Preterm, Premature Birth
The Periviable GOALS Decision Support Tool
The Periviable GOALS (Getting Optimal Alignment around Life Support) decision support tool (DST) is meant to facilitate informed shared decision-making regarding neonatal resuscitation for families facing the threat of a…
- Conditions
- Pregnancy Preterm, Premature Birth, Pregnancy Complications, Obstetric Labor, Premature
- Trial name
- NCT05264779
- Testing
- Periviable GOALS DST
- Where
- 12 sites in United States
- Volunteers
- 300 people
- Sponsor
- Indiana University
Prematurity, Eye Fundus
Benefit of Singing in the Care of Premature Children Undergoing Screening for Retinopathy of Prematurity in the Neonatology and Neonatal Resuscitation Unit of the Dijon University Hospital
As part of the regular procedure for premature births, premature infants undergo several screening examinations, including an examination of the fundus.
- Trial name
- Voix Chantée (NCT03830580)
- Testing
- Positive stimulation (singing)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Vital Signs
The Effect of Postnatal Lying Position on Cerebral Oxygenation in Newborns
In the international delivery room guidelines, it is not specified which position is optimal for the baby stabilization. Here, the investigators want to evaluate the effects of the positions on postnatal adaptation and cerebral…
- Trial name
- NCT05868980
- Testing
- vital signs by postpartum position
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Behcet Uz Children's Hospital
Neonatal Resuscitation, Delivery Room Resuscitation
Supraglottic Airway for Resuscitation Trial
This is a hybrid type 3 effectiveness-implementation parallel cluster randomized superiority trial designed to compare two strategies to promote early supraglottic airway (SA) rescue during neonatal resuscitation, with a focus on…
- Conditions
- Neonatal Resuscitation, Delivery Room Resuscitation, Positive Pressure Ventilation, Infant, Newborn
- Trial name
- SUGAR (NCT07150923)
- Testing
- Enhanced Standard of Care ("Enhanced"), Enhanced Standard of Care ("Enhanced-Plus")
- Where
- 30 sites in United States
- Volunteers
- 36,503 people
- Sponsor
- Children's Hospital of Philadelphia
Septic Shock
Lung Ultrasound-guided Fluid Resuscitation in Neonatal Septic Shock
object name: Lung ultrasound-guided fluid resuscitation in neonatal septic shock. type of study: prospective observational study.
- Trial name
- LUGFRINSS (NCT06144463)
- Testing
- lung ultrasound-guided fluid resuscitation
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Guangdong Second Provincial General Hospital