Clinical trials: Niche Development
Uterine Scar From Previous Cesarean Delivery (Diagnosis)
Uterine Niche After Cesarean Section
In the past decade several articles have described a defect that can be seen on ultrasound at the site of cesarean delivery scar, known as a 'niche' .An incompletely healed scar is a long-term complication of cesarean delivery…
- Trial name
- AMSRM (NCT03787381)
- Testing
- Ultrasound
- Where
- Israel
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Niche
Niche In CEsarean Scar Trial (NICEST)
Rationale: Cesarean delivery (CD) rates are increasing rapidly worldwide. The consequences of cesarean section not only affect the next pregnancies such as uterine rupture or malplacentation but also cause many gynecological…
- Trial name
- NCT05312775
- Testing
- Double-layer uterine closure, Single-layer uterine closure
- Where
- Vietnam
- Volunteers
- 938 people, healthy volunteers welcome
- Sponsor
- Nguyen Thi Thu Ha
Single Layer, Unlocked Sutures
Single Layer With Unlocked Sutures Versus Double Layer Closure of Cesarean Incision and the Risk of Niche Development
This study aimed to compare the development of the uterine niche after single and double closure of cesarean incision.
- Conditions
- Single Layer, Unlocked Sutures, Double Layer Closure, Cesarean Incision
- Trial name
- NCT07554001
- Testing
- Single layer unlocked sutures, Double layer unlocked sutures
- Where
- Egypt
- Volunteers
- 366 people
- Sponsor
- Kafrelsheikh University
Cesarean Section; Dehiscence
Ultrasound Based Study For Niche Development In The Uterine Cesarean Section Scar
The aim of this study is to evaluate different factors affecting niche development in the uterine cesarean section scar in women enrolled 3 to 6 months after cesarean delivery using both TVS and SIS.
- Trial name
- NCT03859258
- Testing
- Transvaginal sonography
- Where
- Egypt
- Volunteers
- 221 people
- Sponsor
- Cairo University
Cesarean Section; Dehiscence
A Randomized Clinical Study Based on Comparison Between Closure of Uterine Incision With Vicryl 2/0 Versus Vicryl 1 in Development of Uterine Niche.
The first group patients underwent double layer closure with split thickness with vicryl 2/0, in continuous, non- locked, 1 cm apart sutures, study group, and the second group, women underwent double layer closure with split…
- Trial name
- NCT05770115
- Testing
- Vicryl 1, Vicryl 2/0
- Where
- Egypt
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cesarean Scar Defect
Impact of a Bladder Flap on Cesarean Scar Niche Development
The goal of this trial is to examine if the completion or omission of a bladder flap impacts the location and formation of cesarean scar niche in women undergoing primary cesarean section.
- Trial name
- B-FIND (NCT07634679)
- Testing
- Bladder flap formation
- Where
- 2 sites in United States
- Volunteers
- 338 people
- Sponsor
- Montefiore Medical Center
Scar Niche, Infertility, Post Menstrual Spotting
The Relationship Between the Number of Ceserean Sections and Scar Niche Development
Aim of the work This study aims to investigate the relationship between the number of previous cesarean sections (CS) and the incidence of a cesarean scar niche.
- Trial name
- NCT07114705
- Testing
- Transvaginal ultrasound
- Volunteers
- 82 people
- Sponsor
- Sohag University
Colon Cancer, Liver Tumors
A Study of Imaging, Blood, and Tissue Samples to Guide Treatment of Colon Cancer and Related Liver Tumors
The purpose of this study is to explore novel ways of diagnosing colon cancer and predicting its propensity to spread to other organs such as the liver.
- Trial name
- NCT03432806
- Testing
- blood draws, colectomy or hepatectomy, Fibroscan test
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cesarean Section; Dehiscence, Uterine Bleeding
Impact of Single- Versus Double-layer Hysterotomy Closure on Cesarean Niche Development: a Randomized Controlled Trial
The objective of this randomized monocentric study is to assess potential variations in the incidence and severity of isthmocele morbidity among women undergoing cesarean section with either single or double-layer closure of the…
- Conditions
- Cesarean Section; Dehiscence, Uterine Bleeding, Uterus; Scar, Uterus Abnormal
- Trial name
- NCT06308172
- Testing
- Hysterotomy closure
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Cesarean Scar Niche
NIche Development With Closure of Cesarean Uterotomy by Modified or Conventional Two-layer Technique
The aim of this trial was to compare two different uterotomy surgical techniques on the occurrence of a uterine niche and the risk of a number of short- and long-term gynecological complications associated with the presence and…
- Trial name
- NICUM (NCT02410395)
- Testing
- Conventional, Modified
- Where
- Denmark
- Volunteers
- 230 people
- Sponsor
- University of Aarhus