Clinical trials: Nitrates
Acute Vulvovaginal Candidiasis
Study Evaluating the Efficacy and Safety of Miconazole Nitrate + Domiphen Bromide Vaginal Cream in the Treatment of Subjects With Acute Vulvovaginal Candidiasis
This study is a multicentre, three-arm, double-blind, randomized controlled, parallel-group, comparative phase II clinical trial to evaluate miconazole nitrate 2% + domiphen bromide vaginal cream in subjects with acute…
- Trial name
- NCT04813822
- Testing
- Miconazole Nitrate 2% + Domiphen Bromide Low Dose, Miconazole Nitrate 2% + Domiphen Bromide High Dose, Miconazole Nitrate 2%
- Where
- 6 sites in Belgium
- Volunteers
- 90 people
- Sponsor
- Aesculape CRO Belgium BV
Gestational Hypertension
Role of the Oral Microbiome in Blood Pressure Regulation in Pregnancy
High blood pressure in pregnancy is associated with poor outcomes for both mum and baby, increasing the risk of pregnancy complications including pre-eclampsia, fetal growth restriction and preterm birth.
- Trial name
- NCT03930693
- Testing
- Beetroot juice
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Tinea
Clinical Assessment of Oxiconazole Nitrate Solid Lipid Nanoparticles Loaded Gel
Clinical study for the developed oxiconazole nitrate solid lipid nanoparticles (SLNs) gel system compared to the corresponding marketed product was conducted on 28 patients with different types of tinea fungal infection.
- Trial name
- NCT03823040
- Testing
- Oxiconazole Nitrate Cream 1%, Oxiconazole nitrate SLNs loaded gel.
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Minia University
Hypertension in Pregnancy, Pre-Eclampsia
The BEET-BP Trial - Investigating the Effect of Dietary Nitrates on Hypertension in Pregnancy
This is a randomised placebo controlled trial investigating the effects of dietary nitrate supplementation on hypertension in pregnancy
- Conditions
- Hypertension in Pregnancy, Pre-Eclampsia, Gestational Hypertension, Pregnancy Induced Hypertension
- Trial name
- NCT04604535
- Testing
- Concentrated beetroot juice
- Where
- United Kingdom
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Type 2 Diabetes
The Effect of Dietary Nitrate Supplementation on Ability of Individuals With Type 2 Diabetes to Perform Exercise
The investigators are conducting a research study to see if increasing the amount of nitrate (a substance found in large quantities in certain vegetables) in the diet can increase the ability of individuals with Type 2 diabetes…
- Trial name
- Ex nit as (NCT02206074)
- Testing
- Beetroot
- Where
- United Kingdom
- Volunteers
- 57 people
- Sponsor
- University of Exeter
Anal Fistula
Effectiveness of Silver Nitrate Solution in the Treatment of Anal Fistula
Effectiveness of silver nitrate solution in treatment of anal fistula is is aimed to be investigated.
- Trial name
- NCT01929525
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Marmara University
Type 2 Diabetes Mellitus
Nitrate and Exercise-induced Cardiac Troponin T in Type 2 Diabetes
Blood cardiac troponin T (cTnT) concentration is a widely used marker of acute cardiac injury. Previous research has shown that type 2 diabetic patients may experience large increments in cTnT levels over the subsequent hours…
- Trial name
- NO troponin (NCT01714674)
- Testing
- Dietary nitrate beverage, NaCl beverage
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Maastricht University Medical Center
Postmenopausal; Menorrhagia, Physical Inactivity
Effects of Dietary Nitrate Intake on Physical Performance of Middle-aged Women
Through a randomized, crossover, triple-blind, placebo-controlled clinical trial, 15 physically inactive hypertensive women will participate a 8-day trial, each with two intervention protocols: 1) placebo and 2) beetroot; in…
- Conditions
- Postmenopausal; Menorrhagia, Physical Inactivity, Motor Activity
- Trial name
- NCT05820321
- Testing
- Beetroot juice rich in nitrate, Beetroot juice NO3 depleted
- Where
- 2 sites in Brazil
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo
Hypertension
Pharmacokinetics of Berkeley Life Oral Nitrate Supplementation
The purpose of the study is to examine the way that a nitric oxide supplement moves through the body. Specifically, the relationship between saliva and blood concentration of the supplement and the elapsed time since taking the…
- Trial name
- NCT06777108
- Testing
- Inorganic Nitrate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Virginia
Resting Metabolic Rate
Modulation of Metabolic Rate by Inorganic Nitrate
The purpose of this study is to determine the effects of sodium nitrate on resting metabolic rate, glucose uptake and formation of reactive oxygen species in humans.
- Trial name
- NCT02022176
- Testing
- Glucose Uptake, Resting metabolic rate, Nitrite infusion
- Where
- Sweden
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Nitrate, Caffeine
The Effects of Nitrate, Caffeine, and Cold Exposure on Cardiovascular Function.
Dietary inorganic nitrate supplementation may have positive implications on cardiovascular function. The aim of this project is to determine if nitrate supplementation can attenuate the effects that caffeine and cold exposure…
- Conditions
- Nitrate, Caffeine, Cold Exposure
- Trial name
- NCT06602921
- Testing
- TruBeet inorganic beetroot juice, Caffeine, Cold pressor test
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Hypertension, Cardiovascular Disease
Effects of Nitrate in Vegetables on Blood Pressure in Subjects With Prehypertension
The purpose of this study is to examine the effect of different vegetables on cardiovascular function in subjects with moderately increased blood pressure.
- Trial name
- DINO (NCT02916615)
- Testing
- High nitrate vegetables, Low nitrate vegetables + nitrate, Low nitrate vegetables
- Where
- Sweden
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Air Pollution
The Effect of Juice Types on the Responses to Air Pollution
The study hypothesis is that drinking different juices will affect the body's responses to air pollution. Subjects will be exposed to air pollution during a 2-hour car ride on the NJ (New Jersey) Turnpike.
- Trial name
- NCT02027415
- Testing
- Beet juice, Orange juice
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Coronary Artery Disease
A Prospective Study to Evaluate the Effect of Chronic Nitrate Therapy on Vasodilation Function in Coronary Heart Disease
Basic studies has showed that sustained use of nitrates might associated with adverse effects on vascular function mediated by an increase in nitrate-induced oxidative stress.
- Trial name
- NCT01430780
- Testing
- nitrate group, control group
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Zhejiang University
Dentin Hypersensitivity
Efficacy of a Potassium Nitrate Containing Herbal Mouthwash to a Potassium Oxalate Mouthwash in Dentinal Hypersensitivity
The goal of this clinical trial is to compare the efficacy of potassium nitrate containing herbal mouthwash to potassium oxalate mouthwash in management of dentinal hypersensitivity.
- Trial name
- NCT06627790
- Testing
- Mouthwash preparation
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Airway Disease
Nitrate Supplementation During Final Examination Stress
The purpose of the present study is to explore the effects of a dietary nitrate supplement on immunity, mood, cardiovascular activity, and lung function during and following final exam stress in both healthy and asthmatic…
- Trial name
- NCT03159273
- Testing
- Beetroot Juice Group
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Southern Methodist University
Aging
Exercise Fatiguability in Older Adults: The Protective Effects of Dietary Nitrate Supplementation
Vascular and skeletal muscle function decline with age and are associated with decreased nitric oxide (NO) bioavailability. Dietary nitrate supplementation in the form of beet root juice increases NO bioavailability and improves…
- Trial name
- NCT05313490
- Testing
- Beetroot Juice
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marquette University
Nitric Oxide, Placebo
Impact of Beetroot Juice Ingestion on Female Rugby Performance
Rugby is a team sport characterized by high-intermittent efforts, due to the importance of realizing intermittent and explosive efforts in rugby the use of nutritional strategies such as beetroot ingestion should be explored with…
- Trial name
- BEETJUICERUGBY (NCT05209126)
- Testing
- Beetroot juice
- Where
- 2 sites in Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Chronic Paronychia
Safety and Efficacy of Intralesional 0.5% Triamcinolone Acetonide in 0.2% Fluconazole Solution vs 0.1% Topical Mometasone Furoate With 2% Miconazole Nitrate Cream in the Treatment of Chronic Paronychia: An Intraindividual Randomized Controlled Trial.
Our objective is to compare the efficacy and safety of intralesional corticosteroids + fluconazole solution to corticosteroid with an antifungal topical preparation, in the management of chronic paronychia.
- Trial name
- NCT07311759
- Testing
- Intralesional triamcinolone acetonide and fluconazole, Topical mometasone furoate and miconazole nitrate, Elica-M®
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentinal Hypersensitivity, Dental Pain
The Effects of Potassium Nitrate in Reducing Dentinal Hypersensitivity
A randomized, controlled, double blind exploratory study to explore the effects of two different potassium nitrate concentrations and water on exposed dentine in reducing dentinal hypersensitivity.
- Trial name
- NCT01587950
- Testing
- Potassium Nitrate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- GlaxoSmithKline