Clinical trials: Nitrogen Balance
Chronic Renal Failure, End-Stage Renal Disease
Dietary Protein Requirements in Hemodialysis Patients
The primary purpose of this study is to assess dietary protein requirements in clinically stable maintenance hemodialysis (MHD) patients.
- Trial name
- NCT02194114
- Testing
- Protein Diet
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Nitrogen Balance, Cancer
Per Kilogram Versus Nitrogen Balance Methods for Daily Protein Requirement in Cancer Patients
The goal of this study is to compare the effects of two dietary protein supplementation methods (per kg [PK] vs nitrogen balance equation [NBE]) on nutritional status, muscle strength, lean body mass, physical performance, and…
- Conditions
- Nitrogen Balance, Cancer, Protein Requirement
- Trial name
- NCT06824636
- Testing
- a personalized diet plan was prepared according to the calculated requirements of each patient by two expert dietitians
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Istanbul University
Men
Nutritional Evaluation of Canola Protein in Comparison With Soy Protein
The objective of the study is to evaluate the nutritional and physiological properties of two canola proteins focusing on the bioavailability in humans.
- Trial name
- NCT01481584
- Testing
- Protein drink - protein isolate, Protein drink - protein hydrolyzate
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Jena
Obesity, Overweight (BMI > 25)
Impact of Protein Supplementation and Resistance Training on Body Composition, Functional Parameters, Metabolic Adaptation, and Nitrogen Balance in Adults Aged 45 Years and Older With Overweight or Obesity Receiving Incretin-based Medications
This study aim to evaluate the effects of protein supplements and resistance training on body composition, functional parameters, metabolic adaptation, and nitrogen balance in adults (aged ≥45 years) with overweight/obesity…
- Conditions
- Obesity, Overweight (BMI > 25), Weight Loss
- Trial name
- PRIME (NCT06950684)
- Testing
- Whey Protein Supplement, Resistance Training Program
- Volunteers
- 180 people
- Sponsor
- Assuta Medical Center
Protein Deficiency
Optimizing Protein Intake and Nitrogen Balance in Adult Critically Ill Patients
The purposes of the study are: To strictly ensure the appropriate level of protein and caloric provision in critical illness, according to the latest literature recommendation; To determine if an association exists between…
- Trial name
- OPINiB (NCT02990065)
- Testing
- PROTEIN SUPPLEMENTATION
- Volunteers
- 40 people
- Sponsor
- University of Padova
Congenital Heart Disease
Nitrogen Balance in Infants After Post Cardiothoracic Surgery
The objective is to the amount of protein infants require after cardiopulmonary bypass surgery.
- Trial name
- NCT01368705
- Testing
- Standard protein delivery, Intervention 1 (2.2g/kg/day), Intervention 2 (3.0 g/kg/day)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- The Hospital for Sick Children
Critical Illness, Malnutrition
Comparative Effect of Protein Prescription Strategies on Nitrogen Balance and Upshots in Critically Ill Patients
This is Interventional clinical trail will be conducted in Internationale hospital ICU s patients with higher nutrition risk. two doses of protein 1 g/kg/day Vs 2 g/ kg day will be given and its outcome will be checked on…
- Conditions
- Critical Illness, Malnutrition, Protein
- Trial name
- NCT04468503
- Testing
- Two differnt protien prescription (ig per kg per day and 2g per kg /day )will be assigned to each group interventional
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Allama Iqbal Open University Islamabad
Obesity
Protein Nutrition During Weight Loss
The purpose of this study is to minimize the loss of lean body mass that occurs during a weight-loss program in obese people by changing the nature of ingested protein and the pattern of protein feeding
- Trial name
- SURPROL-CF-H (NCT00690781)
- Testing
- Pulse casein feeding during energy restriction, Spread casein feeding during energy restriction, Pulse milk soluble protein feeding during energy restriction
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Obesity, Bariatric Surgery
Protein Need and Interest of " Quick Proteins " to the Obese Subject Operated by Bariatric Surgery (BIBOP)
The main objective of the study is to evaluate the protein requirement associated with postoperative weight loss caused by by-pass (shunt which leads to a certain degree of malabsorption) or sleeve gastrectomy (more technically…
- Trial name
- BIBOP (NCT01249326)
- Testing
- bariatric surgery
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Clermont-Ferrand
Obesity
Metabolic Impact of Dietary Protein Supplementation in Surgical Weight Loss
The obesity epidemic has grown rapidly in the United States, and is associated with increased morbidity and mortality rates. Bariatric surgery (BS) has emerged as the most effective treatment for severe obesity.
- Trial name
- MIPS (NCT02269410)
- Testing
- GBP-SPS, GBP-HPS, VSG-SPS
- Volunteers
- 6 people
- Sponsor
- Columbia University
Nitrogen Balance
The Effect of Irregular Meal Pattern on Nitrogen Balance in Healthy Normal-weight Women
Nitrogen balance (NB) is defined as the net difference between the intake of nitrogen (input) and its excretion (output). NB was considered as an indicator of the catabolic stress level.
- Trial name
- NCT05226650
- Testing
- Regular meal pattern, Irregular meal pattern
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Congenital Heart Disease in Children
Impact on the Nitrogen Balance, Autonomy, Safety and Tolerance of Enteral Diets Made of With Nutrilon Without Lactose® Fortified by Concentration Versus by Maltodextrin and Oil Supplementation,After Surgery for Congenital Heart Disease, in Infants.
An adequate nutritional support after a cardiac surgery enhances the morbidity and mortality. After a cardiac surgery, the energy expenditure is estimated to be around 55 kcal/kg/d.
- Trial name
- DIETCHIRCARD (NCT03136900)
- Testing
- Nutrilon without lactose® fortified by concentration, Nutrilon without lactose® fortified by Maltodextrin and oil supplementation
- Where
- Belgium
- Volunteers
- 41 people
- Sponsor
- Queen Fabiola Children's University Hospital
Liver Cirrhoses
Indirect Calorimeter Based Study in Patients With Liver Cirrhosis
Part I- Observational study In the first part , investigator would investigate and compare the energy requirements and substrate utilization in healthy subjects and in patients with liver cirrhosis of various etiologies across…
- Trial name
- METALIC (NCT03871894)
- Testing
- Indirect calorimetry based nutritional intervention till patient in ICU(Intensive care unit), Standard and fixed nutritional intervention till patient in ICU
- Where
- India
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Institute of Liver and Biliary Sciences, India
Inflammatory Bowel Diseases
Effects of Prednisolone and Infliximab on the Regulation of Urea Synthesis in Active Inflammatory Bowel Disease
Loss of total mass of muscles (catabolism) is a serious clinical problem in patients with active inflammatory bowel disease (IBD).
- Trial name
- NCT00955123
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Critically Ill, Nutrition Disorders
Early Goal Nutrition Therapy Guided by Indirect Calorimetry and Nitrogen Balance Among Critically Ill Patients With Acute Kidney Injury (ENGINE Study)
The goal of this clinical trial is to investigate the effects of nutrition therapy guided by indirect calorimetry and nitrogen balance among critically ill patients with acute kidney injury.
- Conditions
- Critically Ill, Nutrition Disorders, Acute Kidney Injury
- Trial name
- ENGINE (NCT06238674)
- Testing
- indirect calorimetry and nitrogen balance, Indirect calorimetry (Standard care nutrition arm)
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Wankawee Jeerangsapasuk
Alcoholic Hepatitis
Effects of Prednisolone and Pentoxifylline on the Regulation of Urea Synthesis in Alcoholic Hepatitis
Loss of total mass of muscles (catabolism) is a serious clinical problem in patients with alcoholic hepatitis. The liver might play an important role in this stress-catabolism by increasing the production of urea during the…
- Trial name
- NCT01245257
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Critically Ill Patients
Influence of Tightly Glucose Control on Hyperglycemic Toxicity and Protein Catabolism in Critically Ill Patients
To compare the differences of urinary nitrogen excretion, nitrogen balance and clinical outcomes between tightly insulin therapy and conventional insulin therapy in the ICU.
- Trial name
- NCT01227148
- Testing
- Tightly glucose control, Conventional glucose control
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Stomach (Gastric) Cancer
PROGAIN Trial in Gastric Cancer Surgery
This randomized study will evaluate whether protein-enriched parenteral nutrition improves early postoperative recovery in patients undergoing gastrectomy for gastric cancer.
- Trial name
- PROGAIN (NCT07488611)
- Testing
- Protein-enriched peripheral parenteral nutrition (Winuf A+ injection), Standard peripheral parenteral nutrition (Winuf injection)
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Soonchunhyang University Hospital
Trauma
The Relation Between Quadriceps Muscle Layer Thickness and Nitrogen Balance for Nutrition Monitoring
Loss of muscle mass is a major cause of intensive care unit-acquired weakness (ICU-AW) and is associated with delayed weaning; prolonged ICU and hospital stay and is an independent predictor of one year mortality.
- Trial name
- NCT04303650
- Testing
- Ultrasound measurement of quadriceps muscle layer thickness
- Where
- Egypt
- Volunteers
- 186 people
- Sponsor
- Zagazig University
End-stage Renal Disease
Arterial pH and Total Body Nitrogen Balances in APD
This study will test the hypothesis that by slightly lowering the acidity of blood (or increasing the pH), dialysis patients utilize protein and amino acids more efficiently.
- Trial name
- NCT00586131
- Testing
- ammonium chloride or sodium citrate/citric acid, Sodium citrate/citratic acid
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center