Clinical trials: No Condition
Respiratory Tract Infections, Cold Symptoms
Beetroot Juice NO Cold Study
Currently, there is a lack of evidence-based prevention strategies for respiratory infection and management of these conditions can be costly to the public.
- Conditions
- Respiratory Tract Infections, Cold Symptoms, Exhaled Nitric Oxide
- Trial name
- NCS (NCT06416228)
- Testing
- Beetroot juice
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Southern Methodist University
Macular Degeneration
Visudyne® in Occult (VIO)
The purpose of this study is to demonstrate that Visudyne therapy in patients who have occult with no classic subfoveal choroidal neovascularization (CNV) lesions will, with an acceptable safety profile, significantly reduce the…
- Trial name
- NCT00121407
- Testing
- Visudyne for injection
- Volunteers
- 364 people
- Sponsor
- QLT Inc.
Myopia
Assessment of the Efficacy and Safety of a DYnaMic Peripheral DegradatiON Myopia Disorder Control in Myopic Children ״DYMOND Study״
The DYMOND study evaluates the safety and effectiveness of TrackSight™, a digital medical application designed to slow myopia (nearsightedness) progression in children during everyday screen use.
- Trial name
- DYMOND (NCT07390500)
- Testing
- TrackSight
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- NovaSight
Type 2 Diabetes Mellitus
Comparison of the Safety and Efficacy of HOE901-U300 With Lantus in Older Patients With Type2 Diabetes Insufficiently Controlled on Their Current Antidiabetic Medications
Primary Objective: To demonstrate the non-inferiority of H0E901-U300 to Lantus, in change of glycated hemoglobin A1c (HbA1c). Secondary Objectives: To demonstrate the superiority of H0E901-U300 in comparison with Lantus in…
- Trial name
- SENIOR (NCT02320721)
- Testing
- Insulin Glargine (HOE901 - U300), Insulin Glargine (HOE901 - U100), Background therapy
- Where
- 162 sites in United States, Argentina and 16 more
- Volunteers
- 1,014 people
- Sponsor
- Sanofi
Healthy, no Evidence of Disease
Resveratrol in Healthy Adult Participants
Resveratrol may prevent cancer in healthy people. Studying samples of blood and urine in the laboratory from participants who are taking resveratrol may help doctors learn more about how this drug is used by the body.
- Trial name
- NCT00721877
- Testing
- resveratrol, pharmacological study, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer
Bevacizumab in Treating Patients Who Have Undergone First-Line Therapy for Metastatic Colorectal Cancer
RATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.
- Trial name
- NCT00544700
- Testing
- bevacizumab, no maintenance
- Where
- 29 sites in Switzerland
- Volunteers
- 265 people
- Sponsor
- Swiss Cancer Institute
Complicated Intra-abdominal Infection, Hosptial Acquired Pneumonia
A Study to Determine the Efficacy, Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) Versus Meropenem (MER) ± Colistin (COL) for the Treatment of Serious Infections Due to Gram Negative Bacteria.
A Phase 3 comparative study to determine the efficacy, safety and tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) versus Meropenem (MER) ± Colistin (COL) for the treatment of serious infections due to Gram…
- Conditions
- Complicated Intra-abdominal Infection, Hosptial Acquired Pneumonia, Ventilator Associated Pneumonia
- Trial name
- REVISIT (NCT03329092)
- Testing
- ATM-AVI, MTZ, MER
- Where
- 157 sites in United States, Argentina and 19 more
- Volunteers
- 422 people
- Sponsor
- Pfizer
Japanese Encephalitis
Safety of Vero Cell - Derived Inactivated Japanese Encephalitis Vaccine (JECEVAX) in Children From 9-24 Months of Age
A study of the study vaccine (JECEVAX- VABIOTECH-Vietnam) and a licensed vaccine (JEVAX-VABIOTECH-Vietnam) is conducted in Vietnamese children, aged 9 to 24 months to assess the safety of the study vaccine compares to licenced…
- Trial name
- JECEVAX-2B (NCT03204227)
- Testing
- JEVAX, JECEVAX
- Where
- 4 sites in Vietnam
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- National Institute of Hygiene and Epidemiology, Vietnam
Follicular Lymphoma
Primary Rituximab and Maintenance
Objectives Primary objective: To evaluate in patients with advanced follicular lymphoma the benefit of maintenance therapy with rituximab after induction of response with chemotherapy plus rituximab in comparison with no…
- Trial name
- NCT00140582
- Testing
- Rituximab
- Where
- 24 sites in Argentina, Australia and 10 more
- Volunteers
- 1,217 people
- Sponsor
- Lymphoma Study Association
Coronary Angiography, Coronary Artery Disease
Assessment Of Total Coronary Circulation Time Using TIMI Frame Count Method (TCCT-TIMI)
The aim of this study is to evaluate and describe the total coronary circulation time (TCCT) by using TIMI frame count method in patients performed coronary angiography.
- Conditions
- Coronary Angiography, Coronary Artery Disease, Coronary Artery Ectasia, Slow-Flow Phenomenon
- Trial name
- TCCT-TIMI (NCT02818127)
- Testing
- coronary angiography
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Vascular and Molecular Cardiology Society
Pancreatic Head Neoplasm, Delayed Gastric Emptying
Nasogastric Decompression Following Pancreaticoduodenectomy
Pancreaticoduodenectomy (PD) remains the gold-standard operation for peri-ampullary neoplasms. Traditionally, gastric decompression via nasogastric intubation has been employed postoperatively to prevent nausea, vomiting…
- Conditions
- Pancreatic Head Neoplasm, Delayed Gastric Emptying, Post Operative Ileus, Whipple Procedure
- Trial name
- whipple (NCT06413888)
- Testing
- pancreaticoduodenectomy
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Baylor College of Medicine
Infective Endocarditis (IE), Heart Valve Disease
The Study Tests if Preoperative Dental Screening is Superior to no Preoperative Dental Screening in Improving the Outcome of Patients Undergoing Surgical Cardiac Valve Replacement or Transcatheter Cardiac Valve Implantation.
This randomized, multicenter, open-label trial evaluates whether preoperative dental screening improves outcomes in patients undergoing surgical or transcatheter cardiac valve intervention.
- Trial name
- SMILE (NCT07511673)
- Testing
- Preoperative dental screening, No preoperative dental screening
- Where
- 5 sites in Sweden
- Volunteers
- 1,300 people
- Sponsor
- Region Skane
Head and Neck Cancer
Neck Surgery in Treating Patients With Early-Stage Oral Cancer
RATIONALE: Surgery may be an effective treatment for oral cancer. It is not yet known whether surgery to remove the tumor and lymph nodes in the neck is more effective than surgery to remove the tumor alone in treating patients…
- Trial name
- NCT00571883
- Testing
- questionnaire administration, psychosocial assessment and care, quality-of-life assessment
- Where
- 27 sites in United Kingdom
- Volunteers
- 652 people
- Sponsor
- The Facial Surgery Research Foundation
There Are no Specific Conditions Under Study, This Study Evaluates the Clinical Decision-Making Associated With Intensive Care Units Rationing
Impact of Bed Availability and Cognitive Load on Intensive Care Unit Bed Allocation: a Vignette-based Clinical Trial
Decisions about ICU beds allocations are made everyday, specially in countries with scarcity of ICU beds, such as Brazil. ICU triage, most of the time, is not structured, which may lead to faulty decision making, possibly leading…
- Trial name
- NCT02430454
- Testing
- Increased cognitive load
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Healthy
ClearView Predicate Comparison Testing
This study serves as a comparison study between the EPIC ClearView and a predicate device.
- Trial name
- NCT01573559
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Cluster Headache
Study of Hypothalamic Metabolism in Spontaneous Cluster Headache Attacks
Cluster headache is characterized by unilateral excruciating head pain and autonomic dysfunction. Hypothalamic overactivity was observed in nitrate-induced cluster-headache and in only one case of spontaneous cluster headache…
- Trial name
- NCT00458770
- Testing
- position emission transaxial tomography
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Spinal Cord Injury at T7-T10 Level, War Injuries Due to Bullets and Fragments
Effects of a Home-Based Rehabilitation on Anthropometric Measures, Sensory-Motor Functions and Independence After Spinal Cord Injury
Background: The scarcity of resources for spinal cord injury (SCI) rehabilitation constitutes a significant obstacle, particularly in war-torn regions experiencing a rise in such injuries.
- Conditions
- Spinal Cord Injury at T7-T10 Level, War Injuries Due to Bullets and Fragments, Spinal Cord Injury L1- L5, Spinal Cord Injury No Sensory/Motor in S4-S5
- Trial name
- HBRSCI (NCT06444672)
- Testing
- Home-based Rehabilitation program, Knee-Ankle-Foot-Orthosis
- Where
- Iraq
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Mosul
Aortic Diseases, Aorto-Iliac Atherosclerosis
Use of Shockwave M5+/L6 IVL Catheter (Intravascular Lithotripsy) in Hostile and Calcified Iliac Access
The study will evaluate, in a controlled setting, the efficacy and safety of the intravascular lithotripsy using Shockwave™ M5+/L6 Peripheral Intravascular Lithotripsy Catheter to facilitate delivery of aortic large-bore devices…
- Conditions
- Aortic Diseases, Aorto-Iliac Atherosclerosis, Peripheral Arterial Disease
- Trial name
- SHOCK-ACCESS (NCT05880641)
- Where
- 6 sites in Italy
- Volunteers
- 40 people
- Sponsor
- EndoCore Lab s.r.l.
Diarrhea
Safety, Efficacy and Cost-effectiveness of Racecadotril in Children With Acute Diarrhea in Mexico
Rationale: Acute diarrhea (AD) is still a significant morbidity-mortality problem worldwide. Although oral rehydration therapy is the cornerstone, its anti-diarrheal effect is a controversial subject.
- Trial name
- Raceca-Mex (NCT01153854)
- Testing
- Racecadotril
- Where
- Mexico
- Volunteers
- 454 people
- Sponsor
- National Institute of Pediatrics, Mexico
Clinical Stage IV Esophageal Adenocarcinoma AJCC v8, Clinical Stage IV Esophageal Squamous Cell Carcinoma AJCC v8
Enhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse Events
This clinical trial studies if enhanced outpatient symptom management with telemedicine and remote monitoring can help reduce acute care visit due to chemotherapy-related adverse events.
- Conditions
- Clinical Stage IV Esophageal Adenocarcinoma AJCC v8, Clinical Stage IV Esophageal Squamous Cell Carcinoma AJCC v8, Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8
- Trial name
- NCT05038254
- Testing
- Best Practice, Patient Monitoring, Questionnaire Administration
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- M.D. Anderson Cancer Center