Clinical trials: No Evidence of Disease
Healthy, no Evidence of Disease, Stage II Breast Cancer
Light-Scattering Spectroscopy for Detection of Breast Cancer
This pilot clinical trial studies light-scattering spectroscopy in finding disease in patients with stage II-III breast cancer. Diagnostic procedures, such as light-scattering spectroscopy, may help find and diagnose breast cancer
- Conditions
- Healthy, no Evidence of Disease, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer
- Trial name
- NCT01755208
- Testing
- light-scattering spectroscopy
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Healthy, no Evidence of Disease
Blood Samples From Healthy Volunteers for Genetic Studies in the East Anglia Region of the United Kingdom
RATIONALE: Studying samples of blood from healthy volunteers in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00757991
- Testing
- polymorphism analysis, laboratory biomarker analysis, questionnaire administration
- Where
- United Kingdom
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Cancer Research UK
Healthy, no Evidence of Disease
Resveratrol in Postmenopausal Women With High Body Mass Index
This pilot phase I trial studies resveratrol in postmenopausal women with high body mass index. Chemoprevention is the use of certain drugs to keep cancer from forming. The use of resveratrol may keep cancer from forming.
- Trial name
- NCT01370889
- Testing
- resveratrol, laboratory biomarker analysis
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer Stage IV, No Evidence of Disease State
Adjuvant Durvalumab Plus Regorafenib vs Untreated Control in Stage IV Colorectal Cancer Patients With no Evidence of Disease (NED): VIVA Trial
The purpose of this study is to evaluate the efficacy of Durvalumab plus Regorafenib versus observation for patients with stage IV colorectal cancer achieving the no evidence of disease state.
- Trial name
- VIVA (NCT05382741)
- Testing
- Durvalumab Injection for intravenous use 500 mg vial solution for infusion, Regorafenib 30 mg capsules
- Where
- Italy
- Volunteers
- 182 people
- Sponsor
- Ospedale Policlinico San Martino
Healthy, no Evidence of Disease
Studying Different Formulations of SR13668 in Healthy Volunteers
This randomized early phase I trial is studying different formulations of SR13668 in healthy volunteers. Giving SR13668 may help doctors learn more about how SR13668 is used by the body.
- Trial name
- NCT00896207
- Testing
- Akt inhibitor SR13668
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Healthy, no Evidence of Disease
Resveratrol in Healthy Adult Participants
Resveratrol may prevent cancer in healthy people. Studying samples of blood and urine in the laboratory from participants who are taking resveratrol may help doctors learn more about how this drug is used by the body.
- Trial name
- NCT00721877
- Testing
- resveratrol, pharmacological study, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Venous Thromboembolism, Bleeding
Avoiding Risks of Thrombosis and Bleeding in Surgery (ARTS) Trial
Avoiding Risks of Thrombosis and bleeding in Surgery (ARTS) trial is a pragmatic, international, multicenter, randomized controlled open label trial comparing a direct oral anticoagulant (DOAC) - oral factor Xa inhibitor apixaban…
- Trial name
- ARTS (NCT06523959)
- Testing
- Apixaban 2.5 MG
- Where
- Finland
- Volunteers
- 5,436 people
- Sponsor
- Clinical Urology and Epidemiology Working Group
Healthy, No Evidence of Disease
Effects of Garlic Supplements on Opioids in Healthy Volunteers
RATIONALE: Garlic supplements may alter the pharmacokinetics of oxycodone, thereby affecting its effectiveness as an opioid analgesic for the relief of moderate or severe pain.
- Trial name
- NCT00499460
- Testing
- garlic powder tablets, oxycodone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Healthy, Obesity
Communication & Peer Support Effects on Physical Activity in Overweight Postmenopausal Women
This randomized clinical trial studies the feasibility of tailored physical activity intervention that is administered using Interactive Voice Response technology and cell phones.
- Conditions
- Healthy, Obesity, Postmenopausal
- Trial name
- BePHIT (NCT01940016)
- Testing
- communication intervention, exercise intervention
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Healthy
Lorazepam, Diphenhydramine Hydrochloride, and Haloperidol Gel in Healthy Volunteers
RATIONALE: Lorazepam, diphenhydramine hydrochloride, and haloperidol gel, when absorbed into the skin, may be an effective treatment for nausea and vomiting.PURPOSE: This clinical trial studies lorazepam, diphenhydramine…
- Trial name
- NCT01204255
- Testing
- lorazepam, diphenhydramine hydrochloride, haloperidol
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Conditions Influencing Health Status, Healthy
Comparing the Reliability of Expressed Prostatic Secretion (EPS) and Post Massage Urine (PMU) for the Prediction of Prostate Cancer Biopsy Outcome
This randomized pilot phase I trial studies the best way, either expressed prostatic secretion (EPS) or post massage urine (PMU) biomarkers, of predicting biopsy results in patients undergoing prostate biopsy.
- Conditions
- Conditions Influencing Health Status, Healthy, Prostate Cancer
- Trial name
- NCT01441687
- Testing
- laboratory biomarker analysis, transrectal prostate biopsy
- Where
- 5 sites in United States
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Healthy, no Evidence of Disease
Bowman-Birk Inhibitor Concentrate in Healthy Men
This randomized phase I trial is studying the side effects and best dose of Bowman-Birk inhibitor concentrate in healthy men. Chemoprevention is the use of certain drugs to keep cancer from forming.
- Trial name
- NCT00679094
- Testing
- Bowman-Birk inhibitor concentrate, pharmacological study, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Healthy, no Evidence of Disease
Diindolylmethane in Preventing Cancer in Healthy Volunteers
This phase I clinical trial studies the side effects and best dose of diindolylmethane in preventing cancer in healthy volunteers.
- Trial name
- NCT00784394
- Testing
- diindolylmethane, pharmacological study, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer
Vaccine Therapy Plus QS21 in Treating Women With Breast Cancer Who Have No Evidence of Disease
RATIONALE: Vaccines made from GM2-KLH and given with QS21 may make the body build an immune response to and kill tumor cells. PURPOSE: Phase I trial to study the effectiveness of GM2-KLH vaccine plus QS21 in treating patients…
- Trial name
- NCT00003357
- Testing
- GM2-KLH vaccine, QS21
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Healthy, no Evidence of Disease, Prostate Cancer
Lycopene in Healthy Male Participants
This randomized phase I trial is studying the side effects and best dose of lycopene in healthy male participants. Chemoprevention is the use of certain drugs to keep cancer from forming.
- Trial name
- NCT00450957
- Testing
- lycopene, pharmacological study
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Lung Cancer
A Phase 3 Study of 99mTC-EC-DG SPECT/CT Versus PET/CT in Lung Cancer
The purpose of this study is to determine if the images of the primary lesions of lung cancer and any metastatic lesions seen from the investigational SPECT/CT 99mTC-EC-DG scans are the same as the PET/CT 18F-FDG scans.
- Trial name
- NCT01394679
- Testing
- (99m Tc) ECDG (Ethylenedicysteine-Deoxyglucose), 18 F FDG followed by PET/CT imaging
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Cell>Point LLC
Metastatic Colorectal Cancer，NED
Maintenance Tislelizumab + Capecitabine to Treat Metastatic Colorectal Cancer
Surgery with integrated treatment for metastatic colorectal cancer (mCRC) has created a new clinical setting known as mCRC with no evidence of disease (NED).
- Trial name
- CAMCO2 (NCT05360277)
- Testing
- Tislelizumab + Capecitabine, Best supportive care
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Yanhong Deng
Stroke, Rehabilitation
Development of a National Protocol for Stroke Rehabilitation in a Multicenter Italian Institution
Due to the importance to use standardized shared protocols in the rehabilitative setting of cerebrovascular diseases, an harmonization and redefinition of the Don Carlo Gnocchi Foundation rehabilitative model was carried out.
- Trial name
- NCT03968627
- Testing
- Rehabilitative intervention
- Where
- Italy
- Volunteers
- 443 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Cardiovascular Diseases
Impact of Rapeseed and Sunflower Oils on Proteomic Biomarkers of Diseases.
This study will test the impact of vegetable oils with contrasting fatty acids composition on biomarkers of health (cardiovascular, kidney diseases and diabetes) after twelve weeks supplementation.
- Trial name
- DOC (NCT04867629)
- Testing
- Rapeseed oil, Sunflower oil
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Anxiety, Depression
Stress and Coping in Caregivers of Younger Patients With Cancer
This research trial studies stress and coping in caregivers of younger patients with cancer. Learning how caregivers of children with cancer experience and cope with chronic stress may help to develop effective programs for…
- Trial name
- NCT02725385
- Testing
- Laboratory Biomarker Analysis, Physiologic Testing, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences