Clinical trials: Nocturnal Hypoxemia
Precapillary Pulmonary Hypertension, Pulmonary Arterial Hypertension
Evolution of Hypoxic Burden and Sympathetic/Parasympathetic Balance in Patients With Pulmonary Hypertension
Background and Rationale: Sleep-disordered breathing and nocturnal hypoxemia are highly prevalent in patients with precapillary pulmonary hypertension (PH), and current guidelines recommend systematic sleep assessment in this…
- Conditions
- Precapillary Pulmonary Hypertension, Pulmonary Arterial Hypertension, Sleep-disordered Breathing, Nocturnal Hypoxemia
- Trial name
- HRV&PH (NCT07464184)
- Testing
- Standard Clinical and Functional Assessment, Overnight Polysomnography
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Rouen
Obstructive Sleep Apnea
Impact Of Closure Of Patent Foramen Ovale On Apnoea-Hypopnoea-Index, Nocturnal Hypoxemia And Systemic Vascular Function In Patients With Obstructive Sleep Apnoea
The purpose of this study in patients with obstructive sleep apnoea (OSA) and concomitant patent foramen ovale (PFO) is to assess the impact of percutaneous PFO closure on nocturnal hypoxemia and apnea/hypopnea, pulmonary and…
- Trial name
- NCT01780207
- Testing
- PFO Closure
- Where
- Switzerland
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Sleep-Disordered Breathing, Glucose Intolerance
Impact of Nocturnal Hypoxemia on Glucose in High Altitude Sleep Disordered Breathing
Sleep disordered breathing is associated with impaired glucose tolerance and incident diabetes. Nocturnal hypoxemia is a potential stimulus of glucose intolerance.
- Trial name
- NCT05462834
- Testing
- Compressed Air, Supplemental Oxygen
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Benign Prostate Hypertrophy(BPH), Obstructive Sleep Apnea( OSA)
Nocturnal Hypoxemia and Benign Prostatic Hyperplasia in OSA Patients
Obstructive Sleep apnea (OSA) is a common sleep disorder characterized by frequent partial or complete obstructions of the upper airway during sleep leading to sleep fragmentation and sympathetic activation.
- Trial name
- NCT07058038
- Where
- Egypt
- Volunteers
- 91 people
- Sponsor
- Mansoura University
OSA - Obstructive Sleep Apnea, Coronary Microvascular Dysfunction (CMD)
The Correlation Between Obstructive Sleep Apnea-Related Nocturnal Hypoxemia Parameters and Coronary Microvascular Dysfunction: A Prospective Cohort Study (SLEEP-CMD)
In a cohort of patients with suspected myocardial ischemia undergoing sleep studies, the objectives of this study were: 1. To determine the association between various obstructive sleep apnea (OSA)-related nocturnal hypoxemia…
- Conditions
- OSA - Obstructive Sleep Apnea, Coronary Microvascular Dysfunction (CMD), Coronary Artery Disease (CAD)
- Trial name
- SLEEP-CMD (NCT07315399)
- Testing
- Polysomnography
- Where
- China
- Volunteers
- 560 people
- Sponsor
- Beijing Anzhen Hospital
Obstructive Sleep Apnea
The Association of CPAP Compliance Study
The purpose of this study is to evaluate the pre and postoperative CPAP compliance rate in OSA surgical patients with or without a CPAP prescription.
- Trial name
- NCT02796846
- Where
- Canada
- Volunteers
- 158 people
- Sponsor
- University Health Network, Toronto
Obstructive Sleep Apnea (OSA), Metabolic Dysfunction-Associated Steatotic Liver Disease
FIB-4 Index, Sleep Apnea Severity, and Nocturnal Hypoxemia
This retrospective study evaluates whether the Fibrosis-4 (FIB-4) index is associated with the severity of obstructive sleep apnea (OSA) and nighttime oxygen desaturation.
- Trial name
- FIB-4-OSA (NCT07798518)
- Where
- Turkey (Türkiye)
- Volunteers
- 373 people
- Sponsor
- Hisar Intercontinental Hospital
Chronic Obstructive Pulmonary Disease
Consequences of Nocturnal and Daytime Hypoxemia in COPD
We will determine whether oxygen therapy lowers the level of substances in the blood which cause inflammation, which is one of the adverse effects of COPD and whether oxygen improves overall well being and quality of life as well…
- Trial name
- NCT00547456
- Testing
- Oxygen
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Northwell Health
Obstructive Sleep Apnea, Hypoxemia
Mechanisms of Endothelial Cell Dysfunction in Sleep Apnea
Sleep apnea is a common sleep disorder characterized by temporary stops in breathing during sleep and has been associated with the development of cardiovascular disease.
- Trial name
- NCT00859950
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Pulmonary Arterial Hypertension (PAH), Sleep-disordered Breathing (SDB)
PAH-SDB: Sleep-Disordered Breathing and Outcomes in Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a progressive pulmonary vascular disease characterized by increased pulmonary vascular resistance, right ventricular dysfunction, and clinically important morbidity and mortality.
- Trial name
- PAH-SDB (NCT07852403)
- Testing
- Standardized Overnight Sleep and Cardiorespiratory Monitoring
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Chinese Pulmonary Vascular Disease Research Group
Obstructive Sleep Apnea
Is My Sleep Tracker Tracking my Sleep?
The purpose of this research study is to collect health and physiological data using commercially available wristband fitness tracker devices (FitBit and Garmin devices) to help determine their accuracy and reliability at…
- Trial name
- NCT06174558
- Testing
- Sleep Tracking Devices
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Respiratory Specialists
Idiopathic Pulmonary Fibrosis, Obstructive Sleep Apnea
FIBRotic Interstitial Lung Disease and Nocturnal OXygen
Home sleep studies - which allow the measurement of breathing while the person sleeps - will be performed on patients with fibrotic interstitial lung disease attending two of the UK's largest respiratory medicine services.The…
- Conditions
- Idiopathic Pulmonary Fibrosis, Obstructive Sleep Apnea, Sleep Disturbance, Sleep Hypoventilation
- Trial name
- FIBRINOX (NCT04586946)
- Where
- 2 sites in United Kingdom
- Volunteers
- 102 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Sleep Apnea, Alveolar Hypoventilation
How Differences in Oximeter Performance May Affect Clinical Decision
In clinical practice discrepancies between overnight SpO2 recordings performed by 2 devices used simultaneously are regularly observed. However, this has not been systematically studied or quantified.
- Conditions
- Sleep Apnea, Alveolar Hypoventilation, Nocturnal Hypoxemia
- Trial name
- NCT04474574
- Testing
- Simultaneous recording of nocturnal SpO2
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University Hospital, Geneva
Interstitial Lung Disease, Fibrosis Lung
FIBRotic Interstitial Lung Disease With Nocturnal hypOXaemia and EXercise Induced desaTuRAtion
This is an observational clinical research study investigating patients with fibrotic interstitial lung disease (fILD), also known as pulmonary fibrosis. It is not known why some patients with fILD clinically deteriorate.
- Conditions
- Interstitial Lung Disease, Fibrosis Lung, Pulmonary Hypertension
- Trial name
- FIBRINOX-EXTRA (NCT06416163)
- Testing
- Prospective
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Nocturnal Hypoxemia
Evaluation of POC Pulse-dose Demand Oxygen Delivery for Nocturnal Hypoxemia
The aim of this study is to describe the effect of the Inogen Rove 6 Portable Oxygen Concentrator on peripheral oxygen saturation in adults receiving supplemental oxygen at night and examine whether the device can adequately…
- Trial name
- NCT06000332
- Testing
- InogenOne Rove 6 Portable Oxygen Concentrator
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Inogen Inc.