Clinical trials: Nodule Solitary Pulmonary
Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple
An Exploratory Clinical Study on the Safety and Efficacy of Autologous NK Cells in the Treatment of Pulmonary Nodules
A single-center, open-label dose-escalation design to evaluate the safety and efficacy of KN5001 in patients with pulmonary nodules.
- Trial name
- NCT07185035
- Testing
- KN5001
- Where
- China
- Volunteers
- 24 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Yield of Cryo Biopsy in Lung Cancer, Solitary Pulmonary Nodule
EBUS Guided Cryo Biopsy of Solitary Pulmonary Nodules
To proof the feasibility and safety of EBUS guided transbronchial cryo biopsies in peripheral lung lesions
- Trial name
- NCT01221493
- Testing
- Cryo biopsy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Heidelberg University
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
Multiparametric Lung MRI With Diffusion-Weighted Imaging in Lung-RADS 4 Lesion Characterization
This study evaluates whether multiparametric chest magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), performed without any contrast material, can distinguish malignant from benign lung lesions that were…
- Conditions
- Solitary Pulmonary Nodule, Multiple Pulmonary Nodules, Lung Neoplasms, Lung Cancer Screening
- Trial name
- NCT07768046
- Testing
- Multiparametric chest MRI with diffusion-weighted imaging
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Pulmonary Nodules, Lung Cancer (Diagnosis)
The Percutaneous Interventional Surgery Control System for Pulmonary Nodule Biopsy
This prospective, single-center, non-inferiority, randomized controlled clinical trial aims to evaluate the efficacy and safety of a percutaneous interventional surgical control system in performing percutaneous needle biopsy of…
- Conditions
- Pulmonary Nodules, Lung Cancer (Diagnosis), Percutaneous Needle Biopsy, Transthoracic Needle Biopsy
- Trial name
- NCT07277088
- Testing
- Percutaneous Needle Biopsy with Interventional Surgical Control System, Conventional Manual Percutaneous Needle Biopsy
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Jiayuan Sun
Lung Cancer
Safety and Efficacy Evaluation of Cryoablation in the Treatment of Ground-Glass Nodules
Lung cancer is the leading cause of cancer-related mortality worldwide, making early diagnosis and intervention critical. With the widespread adoption of low-dose computed tomography (LDCT) screening, the detection rate of…
- Trial name
- NCT07232433
- Testing
- Cryoablation
- Where
- 2 sites in China
- Volunteers
- 90 people
- Sponsor
- Ruijin Hospital
Nodule Solitary Pulmonary, Non-small Cell Carcinoma
Nodify XL2 Classifier Clinical Utility Study in Low to Moderate Risk Lung Nodules
This study evaluates the how addition of the Nodify XL2 test result impacts the clinical management of newly identified solid lung nodules assessed as low to moderate risk of cancer.
- Trial name
- ALTITUDE (NCT04171492)
- Where
- 25 sites in United States, Canada
- Volunteers
- 2,000 people
- Sponsor
- Biodesix, Inc.
Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
Fluorescence-navigated Thoracoscopy for Detection of Small Pulmonary Nodules
Fluorescence-navigated thoracoscopic imaging with indocyanine green (ICG) is a novel technique for detection of small pulmonary nodules other than traditional radiography or intraoperative palpation.
- Trial name
- NCT04165603
- Testing
- Preoperative Infusion of Indocyanine Green
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Peking University People's Hospital
Lung Nodules, Biopsy
Efficacy and Safety of Robotic-assisted Bronchoscopy Combined With the ICNVA Strategy in Biopsy of Peripheral Pulmonary Nodules
To assess the efficacy and safety of robotic-assisted bronchoscopy system (bronchial navigation and positioning device) combined with ICNVA strategy for peripheral pulmonary nodule biopsy through a prospective, single-center…
- Conditions
- Lung Nodules, Biopsy, Navigation, Spatial
- Trial name
- NCT07136961
- Testing
- Robot-Assisted Bronchoscopy (RAB)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Lung Nodules, Lung Cancer
The Impact of Thoracic Paravertebral Nerve Block At Different Positions on Pain Relief in Patients Undergoing Single-Port Thoracoscopic Partial Lung Resection
Thoracic surgery is widely recognized as one of the most painful surgical procedures. Compared to open thoracotomy, video-assisted thoracoscopic surgery (VATS) offers similar therapeutic outcomes with less invasiveness…
- Trial name
- NCT06789276
- Testing
- Supine position, lateral decubitus position
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital of Soochow University
SPN, Lung Cancer
Augmented Reality-assisted Localization of Solitary Pulmonary Nodules for Precise Sublobar Lung Resection
With the popularization of CT screening, the detection rate of small lung nodules has greatly increased. Therefore, the clinical thoracoscopic lung nodule biopsy and sub-lobectomy for radical resection of lung cancer are greatly…
- Trial name
- ARPL (NCT05162235)
- Testing
- Augmented Reality-assisted localization of solitary pulmonary nodule
- Volunteers
- 20 people
- Sponsor
- Shanghai Chest Hospital
Multiple Pulmonary Nodules
Single-Center CyTOF and Viral Imprinting Study in Postoperative Multiple Pulmonary Nodules
This multicenter prospective cohort study will enroll adults who have undergone resection of a primary pulmonary nodule and have residual multiple pulmonary nodules or require routine postoperative pulmonary nodule follow-up.
- Trial name
- NCT07647055
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Pneumothorax, Pulmonary Nodule, Solitary
Multi-Reader Retrospective Study Examining Carebot AI CXR 2.0.21-v2.01 Implementation in Everyday Radiology Clinical Practice
The primary objective is to evaluate the performance parameters of the proposed DLAD (Carebot AI CXR) in comparison to individual radiologists.
- Conditions
- Pneumothorax, Pulmonary Nodule, Solitary, Atelectasis, Subcutaneous Emphysema
- Trial name
- NCT05963945
- Testing
- Carebot AI CXR
- Where
- Czechia
- Volunteers
- 956 people
- Sponsor
- Carebot s.r.o.
Peripheral Pulmonary Lesion, Lung Nodule, Solitary
Robotic Versus Electromagnetic Bronchoscopy for Pulmonary LesIon AssessmeNT Using Integrated Intraprocedural Imaging
RELIANT 2 is a pragmatic randomized controlled trial. The goal of this study is to compare the diagnostic yield of robotic assisted bronchoscopy with integrated cone beam computed tomography to that of electromagnetic navigation…
- Trial name
- RELIANT 2 (NCT06654271)
- Testing
- Robotic assisted bronchoscopy (RAB), Electromagnetic navigation bronchoscopy (ENB)
- Where
- 4 sites in United States
- Volunteers
- 440 people
- Sponsor
- Vanderbilt University Medical Center
Solitary Lung Nodule, Multiple Pulmonary Nodules
A Prospective, Non-interventional Cohort Study of Subsolid Pulmonary Nodules
Some studies have shown that the model for judging and predicting the growth of sub-solid pulmonary nodules through big data and deep learning can detect nodule growth earlier.
- Trial name
- NCT06458673
- Where
- China
- Volunteers
- 1,184 people
- Sponsor
- Guangdong Provincial People's Hospital
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
A Multi-Center Trial of the ProLung Test™
The primary Study hypothesis is that the ProLung Test will demonstrate safety and efficacy in the risk stratification of patients with pulmonary lesions identified by CT that are suspicious for lung cancer.
- Trial name
- NCT01566682
- Where
- 15 sites in United States
- Volunteers
- 420 people
- Sponsor
- Fresh Medical Laboratories
Pulmonary Nodule, Solitary, Lung; Node
The Early Diagnosis of Pulmonary Nodule Based on Multi-dimension Messages
The researchers are aimed to investigate the early diagnosis of pulmonary nodule based on DNA, RNA, protein, metabolites through analyzing the serum, plasma, urine, faeces, peripheral blood mononuclear cell (PBMC), exhaled breath…
- Trial name
- NCT04005677
- Testing
- The serum, plasma, urine, faeces, peripheral blood mononuclear cell (PBMC), exhaled breath condensate and the clinical characteristics are collected.
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Peripheral Pulmonary Lesion
Evaluate the Diagnostic Value of BTPNA for PPL: a Real-world Study
The study is designed as a multicenter prospective trial of BTPNA for the diagnosis of peripheral pulmonary lesions in the real world.
- Trial name
- NCT04597346
- Testing
- Bronchoscopic Transparenchymal Nodule Access
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Chest Hospital
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
Evaluate the Utility of the ProLung Test as Adjunctive to CT Scan in the Diagnosis of Lung Cancer
A Study to evaluate the utility of the ProLung Test as an adjunct to CT scan in the diagnosis of lung cancer.
- Trial name
- NCT01958931
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Fresh Medical Laboratories
Lung Cancer
Non-Invasive Biomarkers For Early Detection Of Lung Cancers
Recent studies have shown that low-dose chest CT scans can detect lung cancers in high-risk populations (age >50yo, >30 pack-years of tobacco use), and can lower cancer mortality.
- Trial name
- ISRUSAL01 (NCT01580332)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Douglas W. Johnson MD, FACR
Lung Cancer
A Single-center Prospective Cohort Study for Pure Pulmonary Ground Glass Nodules in Women Preparing for Pregnancy
In this study, about 200 pure GGO in women preparing for pregnancy will be included for a 5-year follow-up. The aim of this study is to elucidate the biological nature of pulmonary GGO lesion in women preparing for pregnancy and…
- Trial name
- NCT04596371
- Testing
- pure pulmonary ground glass nodules in women preparing for pregnancy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Zhongshan Hospital