Clinical trials: Non Insulin Dependent Diabetes Mellitus
Type 2 Diabetes, Inpatient
Effect of Glycemic Variability on Autonomic Tone in Hospitalized Patients With Type 2 Diabetes
Glycemic variability has been associated with mortality in hospitalized patients with hyperglycemia. However, it is unknown how modulation of glycemic variability would impact outcomes.
- Trial name
- NCT01409239
- Testing
- Intravenous insulin, Subcutaneous Insulin
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Kathleen Dungan
Diabetics Mellitus Type 1, Diabetes Mellitus Type 2
Testing the Effect of the InsuPad Device in Daily Life Conditions
This is the test protocol for the InsuPad device. The aim of the study is to show economical benefit when using the InsuPad device, by testing the effect of the InsuPad device on reducing injected insulin dose while keeping the…
- Trial name
- NCT01594801
- Testing
- InsuPad
- Where
- 9 sites in Germany
- Volunteers
- 145 people
- Sponsor
- Insuline Medical Ltd.
Diabetes Mellitus, Oxidative Stress
Low Dose β-carotene Supplementation Diminishes Oxidative Stress in Type 2 Diabetics and Healthy Individuals
Since diabetes has multiple etiologies and oxidative stress one of the proposed mechanisms, the objective is to determine the effect of supplementation with β-carotene to type 2 diabetics and healthy individuals, on iron…
- Conditions
- Diabetes Mellitus, Oxidative Stress, Iron Metabolism Disorders
- Trial name
- NCT01477112
- Testing
- Betacarotene, Controls. No treatment
- Where
- Venezuela
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Instituto Venezolano de Investigaciones Cientificas
Diabetes Mellitus, Type 2
Examining Genetic Influence on Response to Beta-Blocker Medications in People With Type 2 Diabetes
Beta-blockers are medications used to treat cardiovascular disease (CVD) symptoms, including high blood pressure and chest pain.
- Trial name
- NCT00925119
- Testing
- Atenolol
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Maryland, Baltimore
Type 2 Diabetes, Severe Mental Disorder
Psychosis and Type 2 Diabetes Study (PODS)
People with severe mental illness (SMI), defined as psychotic and bipolar disorders, die 17-20 years earlier than the general population, the most common cause of death being cardiovascular diseases (CVD).
- Trial name
- NCT05496907
- Testing
- Diabetes specialist nurse-led collaborative care intervention
- Where
- 9 sites in United Kingdom
- Volunteers
- 16 people
- Sponsor
- King's College London
Type 2 Diabetes, Circadian Rhythm
Determining Circadian Metabolic and Behavioural Rhythms in Patients with and Without Type 2 Diabetes
The goal of the present clinical descriptive study is to characterize and quantify the potential hormonal chronobiological differences between individuals with type 2 diabetes (T2D) and healthy age and weight-matched controls as…
- Trial name
- Cir-D-Brain (NCT06243172)
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
Maturity-onset Diabetes of the Young
Pathophysiological Implications of the Incretin Hormones in Maturity Onset of Diabetes of the Young (MODY)
The purpose of this study is to describe the incretin effect and postprandial incretin response in patients with MODY2 and MODY3 and a group of matched healthy subjects.
- Trial name
- NCT01342939
- Testing
- Oral Glucose Tolerance Test (OGTT), iso glycaemic intravenous (iv) glucose infusion (IIGI), Meal test
- Where
- Denmark
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Pressure Ulcer, Foot Ulcer, Diabetic
Use of Santyl Within an Accountable Care Organization
This study is designed to assess the comparative effectiveness of SANTYL® versus standard of care in the treatment of pressure ulcers and diabetic foot ulcers within the continuum of care of an ACO.
- Trial name
- NCT02716519
- Testing
- Santyl, Standard Care
- Where
- United States
- Sponsor
- Smith & Nephew, Inc.
Type 2 Diabetes, Obesity
Effects of Caloric Restriction in Obesity and Type 2 Diabetes
The study investigates whether a long-term 25% caloric restriction can prevent onset and/or progression of renal function deterioration, retinal involvement and cardiovascular complications in overweight/obese type 2 diabetic…
- Trial name
- CRESO2 (NCT01930136)
- Testing
- Calorie restriction (25%), Ad libitum health diet
- Where
- Italy
- Volunteers
- 103 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Diabetes Mellitus, Type 2
OASIS: Peer Support for T2DM in Appalachia (Peer Coaches)
The goal of this clinical trial is to compare the effects of peer coaching models in older adults with unmanaged type two diabetes.
- Trial name
- OASIS (NCT06003634)
- Testing
- Peer Coaching - Peer Participants A, Peer Coaching - Peer Participants B, Peer Coaching - Peer Participants C
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Type 2 Diabetes Melitus, Inflammation Biomarkers
Effect of Vitamin D on Inflammatory Markers in Type 2 Diabetes Mellitus in Mexico.
Type 2 Diabetes Mellitus (T2DM) is a very common disease in Mexico, and its long-term complications affect years of healthy life and a high cost in treatmenty. T2DM is a chronic disease associated to inflammation.
- Trial name
- NCT06993064
- Testing
- 4000 IU of Vitamin D3
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Universidad Autonoma del Estado de Mexico
Diabetes
Protein Hydrolyzation and Glycemic Control
The insulinotropic effects of protein hydrolysate/amino acid ingestion have been shown to regulate blood glucose homeostasis in both type 2 diabetes patients and normoglycemic controls.
- Trial name
- NCT01034618
- Testing
- Protein hydrolyzation
- Where
- Netherlands
- Sponsor
- Maastricht University Medical Center
Diabetes Mellitus, Type 2, Metabolic Associated Fatty Liver Disease
Correlation Between Serum Nociceptin and Sympathetic Nerve Activity in Diabetic Patients With MAFLD
This observational study aims to investigate the relationship between serum nociceptin levels and sympathetic nervous system activity in patients with both type 2 diabetes mellitus (T2DM) and metabolic associated fatty liver…
- Trial name
- NCT07663682
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Hospital of Shanxi Medical University
Diabetes Mellitus, Type 2
Feasibility Study on the Impact of Economic Incentives to Improve the Management of Type 2 Diabetes Mellitus
This feasibility study aims to compare the implementation process of three different interventions that use economic incentives to promote lifestyle behavioral changes in patients with type 2 diabetes mellitus, and to identify…
- Trial name
- REDEEM-Pilot (NCT02891382)
- Testing
- Diabetes education, Goal setting, Companion Support
- Where
- Peru
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidad Peruana Cayetano Heredia
Type 2 Diabetes Mellitus, Mild Cognitive Impairment
Effects of Henagliflozin on the Brain Function in T2DM Patients With Mild Cognitive Impairment: a Randomized, Parallel Controlled Clinical Trial
This is a prospective, randomized, open label, parallel, 16-week study to explore and evaluate the therapeutic effects of Henagliflozin on the cognitive function, olfactory function, and odor-induced brain activation in T2DM…
- Trial name
- NCT06085703
- Testing
- Henagliflozin, Gliclazide
- Where
- China
- Volunteers
- 24 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Diabetes Mellitus, Type 2, Heart Failure
Randomised Trial of Health Coaching in Secondary Prevention of Diabetes and Heart Disease
A randomised trial with individual patients as units of observation will be carried out. Health coaching is used to modify health behaviour and thus improve disease control and health status, as well as use of health care…
- Conditions
- Diabetes Mellitus, Type 2, Heart Failure, Coronary Disease
- Trial name
- TerVa (NCT00552903)
- Testing
- Health coaching
- Where
- Finland
- Volunteers
- 1,500 people
- Sponsor
- Paijat-Hame Hospital District
Diabetes Mellitus, Type 2, Prediabetic State
Finding the Patient's Voice Diabetes Prevention Programs
This study uses patient engagement to develop a diabetes prevention program focused on adolescents and families.
- Trial name
- NCT02700503
- Testing
- Encourage 2.0
- Where
- 3 sites in United States
- Volunteers
- 146 people
- Sponsor
- Indiana University
Type 2 Diabetes Mellitus
A Study to Test the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MK1006 (MK-1006-002)(COMPLETED)
This study will assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of single doses of MK1006
- Trial name
- NCT00757601
- Testing
- MK1006
- Volunteers
- 25 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus, Type 2
Effect of a Dietary Intervention on Intracellular Lipid Levels, Insulin Sensitivity, and Glycemic Control in Type 2 Diabetes
The purpose of this study is to compare the effects of a low-fat, plant-based dietary intervention and a portion-controlled dietary intervention (compliant with current American Diabetes Association (ADA) guidelines) on changes…
- Trial name
- NCT04088981
- Testing
- Dietary intervention
- Where
- United States
- Sponsor
- Physicians Committee for Responsible Medicine
Type2 Diabetes Mellitus
Investigate the Efficacy and Safety of Low-Glu in Patients Newly Diagnosed With Type II Diabetes Mellitus
Ficus deltoidea leaves, Cinnamomum cassia and Black seed powdered extract have long been used for the treatment of type 2 diabetes mellitus.
- Trial name
- NCT05343767
- Testing
- Natural Wellness Low-Glu low dose, Natural Wellness Low-Glu high dose, Metformin
- Where
- Egypt
- Volunteers
- 198 people
- Sponsor
- Natural Wellness Egypt
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