Clinical trials: Non Organic Psychosis
Schizophrenia, Psychotic Disorders
Bergen Psychosis Project 2 - The Best Intro Study
In the Bergen Psychosis Project 2 the antipsychotic drugs aripiprazole, amisulpride, and olanzapine will be compared head-to-head in patients with schizophrenia and related psychoses and followed for 12 months.
- Trial name
- BP2 (NCT01446328)
- Testing
- Amisulpride, Aripiprazole, Olanzapine
- Where
- 4 sites in Austria, Norway
- Volunteers
- 151 people
- Sponsor
- Haukeland University Hospital
Schizophrenia, Schizoaffective Disorder
CLOZAPINE Response in Biotype-1
The CLOZAPINE study is designed as a multisite study across 5 sites and is a clinical trial, involving human participants who are prospectively assigned to an intervention.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar 1 Disorder
- Trial name
- NCT04580134
- Testing
- clozapine, risperidone
- Where
- 5 sites in United States
- Volunteers
- 524 people
- Sponsor
- University of Texas Southwestern Medical Center
Schizophrenia, Psychosis
RCT Examining the Effectiveness of Digital Picture Frame Use in Inpatient Setting
This study will be a randomized controlled trial that investigates the effectiveness of digital picture frames (DPF) installed in inpatient rooms on long stay inpatient wards servicing schizophrenia clients at CAMH.
- Conditions
- Schizophrenia, Psychosis, Psychosis NOS
- Trial name
- NCT02950571
- Testing
- Digital Picture Frame, Standard Care
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Centre for Addiction and Mental Health
Psychosis, Bipolar Disorder
Young People and Illness Management and Recovery (IMR)
The study is a combined clinical patient outcome study and a health-services research sub-study. Illness management and recovery (IMR) constitutes an evidence-based practice with 11 modules focusing on personal recovery developed…
- Conditions
- Psychosis, Bipolar Disorder, Other Diagnoses and Conditions
- Trial name
- NCT04778085
- Testing
- Illness management and recovery, Semi-structured interviews
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- University Hospital, Akershus
Schizophrenia and Related Disorders, Psychosis
Ketosis Impact on Signs & Symptoms of Schizophrenia and Bipolar disorderS
The goal of this clinical trial is to learn if a ketone drink can improve signs and symptoms of patients with a schizophrenia-spectrum disorder (SSD), or a bipolar-spectrum disorder (BD).
- Conditions
- Schizophrenia and Related Disorders, Psychosis, Bipolar and Related Disorders, Manic Episode
- Trial name
- KISSeS (NCT06426134)
- Testing
- (R)-3-hydroxybutyl (R)-3-hydroxybutyrate), Maltodextrin, Fructose, Pectin, Sodium alginate, Sodium chloride
- Where
- Netherlands
- Volunteers
- 28 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Schizophrenia
Melatonin for Prevention of Metabolic Side Effects of Olanzapine
The purpose of this study is to determine whether melatonin can prevent metabolic side effects of olanzapine such as weight gain, elevated glucose concentrations and lipid abnormalities.
- Trial name
- NCT01593774
- Testing
- Melatonin
- Where
- Iran
- Volunteers
- 36 people
- Sponsor
- Guilan University of Medical Sciences
First-Episode Psychosis
Clinical Interviews With Detainees With Early Psychosis
The investigators are studying a jail-based intervention to reduce the duration of untreated psychosis (DUP) among young adults with previously undetected first-episode psychosis who are detained in jail.
- Trial name
- Interview (NCT03962348)
- Testing
- Specialized Early Engagement Support Service
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Columbia University
Schizophrenia
Improving Negative Symptoms of Psychosis In Real-world Environments
This study will compare Cognitive Behavioral Social Skills Training-Compensatory Cognitive Training (CBSST-CCT) to a goal-focused supportive contact group to see which intervention better improves symptoms and functioning in…
- Trial name
- INSPIRE (NCT02170051)
- Testing
- CBSST-CCT, Goal focused supportive contact
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of California, San Diego
Parkinson Disease, Parkinson Disease Psychosis
Characterization and Progression of Minor Phenomena in Parkinson's Disease (PD)
Parkinson's disease psychosis encompasses a range of symptoms, including minor phenomena, frank hallucinations, and delusions. Minor phenomena include passage hallucinations (fleeting sense of a person, animal or object passing…
- Conditions
- Parkinson Disease, Parkinson Disease Psychosis, Hallucinations, Delusion
- Trial name
- NCT05240339
- Testing
- Observation of minor phenomena
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Rochester
Psychosis
Cbt for Psychosis and Affect on Psychosis Symptoms
This study aims to examine the effectiveness of cognitive behavior therapy for psychosis in first episode patients and see the outcome of CBT on psychotic symptoms.
- Trial name
- cbtpaps (NCT02653729)
- Testing
- cognitive behaviour therapy, Espidone, Olepra
- Volunteers
- 50 people
- Sponsor
- Aisha Andleeb
Prodromal Schizophrenia, Psychosis
Feasibility Trial of a Lifestyle Intervention for CHR-P
The present study will assess the feasibility and social validity of an adjunctive health promotion group for youth and clinical high risk for psychosis (CHR-P).
- Conditions
- Prodromal Schizophrenia, Psychosis, Psychological Disorder, Psychological Stress
- Trial name
- NCT05532683
- Testing
- Health Behaviors Group
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of California, Los Angeles
Schizophrenia, Psychosis
Glutamate, Brain Connectivity and Duration of Untreated Psychosis
The early stages of schizophrenia are associated with significant decreases in social and intellectual abilities, with more declines in chronic disease.
- Conditions
- Schizophrenia, Psychosis, Schizoaffective Disorder
- Trial name
- DUP (NCT02034253)
- Testing
- Risperidone
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Psychosis
The Relationship Between Autobiographical Memory and Motivation
People with a diagnosis of psychosis often experience low motivation and pleasure when thinking about doing future activities. This leads, quite understandably, to doing fewer activities they used to enjoy and not taking up…
- Trial name
- NCT03677635
- Testing
- Guided Autobiographical Memory Recall
- Where
- 2 sites in United Kingdom
- Volunteers
- 31 people
- Sponsor
- King's College London
Psychotic Disorders, Alzheimer Disease
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease
This is a multicenter, randomized, double-blind, parallel-group, placebo-controlled, flexible-dose study evaluating the efficacy, safety, and tolerability of ITI-1284 compared with placebo in the treatment of psychosis in…
- Trial name
- NCT06540833
- Testing
- ITI-1284
- Where
- 69 sites in United States, Bulgaria and 8 more
- Volunteers
- 370 people
- Sponsor
- Intra-Cellular Therapies, Inc.
Schizophrenia, Substance Use
Effects of Physical Activity in Psychosis
Physical health problems are common in schizophrenia with a two- to three-fold increased morbidity and mortality rate, resulting in a 20 years reduction in life expectancy.
- Trial name
- EPHAPS (NCT02205684)
- Testing
- Computer game skills training, Physical activity
- Volunteers
- 126 people
- Sponsor
- Sykehuset i Vestfold HF
Chromosome 22q11.2 Deletion Syndrome
Genetics and Psychopathology in the 22q11 Deletion Syndrome
The purposes of this study are to: 1. study the nature and longitudinal course of psychiatric symptoms in children with the 22q11.2 deletion syndrome and 2. identify genes that contribute to the occurrence of these symptoms.
- Trial name
- NCT00161109
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Psychosis, Social Behavior
Virtual Reality Assisted CBT for Social Difficulties: a Feasibility Study in Early Intervention for Psychosis Services
People experiencing psychosis might find social interactions stressful and avoid them. This can result in isolation and can affect relationships, employment and quality of life.
- Conditions
- Psychosis, Social Behavior, Paranoia, Social Anxiety
- Trial name
- NCT04310475
- Testing
- Virtual reality assisted CBT
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- King's College London
HIV/AIDS, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Youth to Text or Telehealth for Engagement in HIV Care
Youth To Text or Telehealth for Engagement in HIV Care (Y2TEC) is a randomized control pilot to assess the feasibility and acceptability of delivering a targeted problem-solving intervention to youth ages 18-29 living with HIV…
- Conditions
- HIV/AIDS, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Depression, Substance Use
- Trial name
- Y2TEC (NCT03681145)
- Testing
- Counselor delivered telehealth intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Schizophrenia, Schizoaffective Disorder
SUCCEED Africa: Support, Comprehensive Care and Empowerment of People With Psychosocial Disabilities
Although psychotic disorders typically affect less than 1% of the population, they are a significant cause of disability worldwide.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizotypal Disorder, Acute and Transient Psychotic Disorder
- Trial name
- SUCCEED (NCT06007105)
- Testing
- SUCCEED Community-Based Intervention
- Where
- 4 sites in Malawi, Nigeria and 2 more
- Volunteers
- 425 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Psychosis
Predicting Psychotic Relapse Using Speech-Based Early Detection
Psychotic disorders, including schizophrenia and affective psychosis, are severe mental health conditions marked by recurrent episodes that contribute to long-term disability.
- Trial name
- MOTS+ (NCT06978894)
- Where
- 3 sites in Canada
- Volunteers
- 250 people
- Sponsor
- Douglas Mental Health University Institute
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