Clinical trials: Non Organic Psychosis
Psychotic Disorders
Group Training for Social Skills in Psychosis
The purpose of this study is to assess the feasibility of a social skills training group for people with psychosis.
- Trial name
- GRASP (NCT02181777)
- Testing
- GRASP, Standard care
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- King's College London
Major Depressive Disorder, Psychotic Disorders
An International Extension Study of Corlux for Recurrent Psychotic Symptoms in Psychotic Major Depression
Corlux (mifepristone) is a new medication that modulates the body's use of a hormone called cortisol. Under normal conditions, cortisol and other hormones are created by the body in response to physical and emotional stress…
- Trial name
- NCT00128505
- Testing
- Mifepristone
- Where
- 19 sites in Bulgaria, Croatia and 2 more
- Volunteers
- 104 people
- Sponsor
- Corcept Therapeutics
Psychosis, Schizophrenia
Effects of Aripiprazole and Haloperidol on Mesolimbic System Functioning
The main objective is to investigate if the brain activation signature of a typical antipsychotic agent is dissociable from a newer drug with a pharmacological profile that differs from both typical and atypical antipsychotics…
- Trial name
- Arip_200901 (NCT01161277)
- Testing
- Aripiprazole, Haloperidol
- Where
- Norway
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Psychosis
Source-monitoring & Psychosis
Source-monitoring is a cognitive process that refers to the ability to remember the source of an information. Some studies have showed source-monitoring deficits in patients with schizophrenia as well as in individuals at…
- Trial name
- SOURIPSY (NCT04236531)
- Testing
- Cognitive tests and neuroimaging
- Where
- 2 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Psychotic Disorders
A Study of Taurine in Patients With First-episode Psychosis Receiving Antipsychotic Treatment
The purpose of this study is to determine whether Taurine 4g is effective with antipsychotic medication in the treatment of First Episode Psychosis.Taurine may have an effect on cognition and symptoms.
- Trial name
- NCT00420823
- Testing
- Taurine 4g
- Where
- 2 sites in Australia
- Volunteers
- 121 people
- Sponsor
- Melbourne Health
Schizophrenia
A Trial of 10 and 30 mg Doses of CVL-231 (Emraclidine) in Participants With Schizophrenia
This is a Phase 2, multicenter, randomized, double-blind, placebo-controlled, parallel-group, 6-week trial to evaluate the efficacy, safety, and tolerability of 2 fixed doses of CVL-231 (Emraclidine) (10 mg QD and 30 mg QD) in…
- Trial name
- NCT05227690
- Testing
- Emraclidine 10 mg, Emraclidine 30 mg
- Where
- 25 sites in United States, Bulgaria
- Volunteers
- 385 people
- Sponsor
- AbbVie
Early Psychosis, Psychosis
State Representation in Early Psychosis 2
This observational study will examine behavioral and electroencephalography measures related to state representation in individuals with early psychosis and healthy control participants.
- Conditions
- Early Psychosis, Psychosis, Schizophrenia, Bipolar Disorder With Psychosis
- Trial name
- STEP2 (NCT07834203)
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Schizophrenia Disorders, Schizoaffective Disorder
Randomized Clinical Trial of iTEST: A Blended Intervention Targeting Introspective Accuracy
The purpose of this study is to evaluate the effectiveness of a psychosocial intervention called iTEST for people with psychotic disorders that targets introspective accuracy, or the ability to accurately gauge ones abilities.
- Conditions
- Schizophrenia Disorders, Schizoaffective Disorder, Psychotic Disorder
- Trial name
- iTEST R33 (NCT07098169)
- Testing
- iTEST, Active Control
- Where
- 3 sites in United States
- Volunteers
- 201 people
- Sponsor
- University of California, San Diego
Schizophrenia, Schizo Affective Disorder
Mobile Enhancement of Motivation in Schizophrenia
Motivation deficits are a strong determinant of poor functional outcomes in people with schizophrenia. Mobile interventions are a promising approach to improving these deficits, as they can provide frequent cues and…
- Conditions
- Schizophrenia, Schizo Affective Disorder, Psychosis
- Trial name
- NCT03059771
- Testing
- Mobile Enhancement of Motivation (MEMS), Control
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Indiana University
Serious Mental Illness
Efficacy of an Occupational Time Use Intervention for People With Serious Mental Illness
The purpose of this study is to test the efficacy of a new Occupational Time Use Intervention designed to increase activity participation and improve meaning in the lives of people with serious mental illness living in the…
- Trial name
- NCT00520728
- Testing
- Occupational Time Use Intervention
- Volunteers
- 18 people
- Sponsor
- Queen's University
Schizophrenia
Transcutaneous Non-invasive Vagus Nerve Stimulation (t-VNS) in the Treatment of Schizophrenia
Randomized, controlled, double-blind, two-armed clinical investigation to show the efficacy and safety of transcutaneous vagus nerve stimulation (t-VNS), applied at the left auricle, in schizophrenia.
- Trial name
- 02VNS2009 (NCT01176721)
- Testing
- t-VNS verum
- Where
- 2 sites in Germany
- Volunteers
- 20 people
- Sponsor
- cerbomed GmbH
Methamphetamine Induced Psychosis
Psychiatric Symptom Predictors in Methamphetamine-Induced Psychosis
This longitudinal observational study aimed to investigate environmental, familial, and individual factors associated with psychiatric symptom severity in participants diagnosed with methamphetamine-induced psychotic disorder…
- Trial name
- NCT07459257
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Elazığ Mental Health and Diseases Hospital
Schizophrenia, Caffeine
The Impact of Caffeine on Cognition in Schizophrenia
Caffeine is the most used psychoactive drug in Canada, with regular consumption by 88% of the adult population, While rates of caffeine consumption are considered to be high in the general population, there is some evidence that…
- Trial name
- NCT02832401
- Testing
- Caffeine
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Parkinson's Disease Psychosis
A Study of the Safety and Tolerability of Pimavanserin (ACP-103) in Patients With Parkinson's Disease Psychosis
To assess the long-term safety and tolerability of ACP-103 in subjects with Parkinson's disease psychosis.
- Trial name
- NCT00550238
- Testing
- Pimavanserin tartrate (ACP-103)
- Where
- 135 sites in United States, Austria and 12 more
- Volunteers
- 459 people
- Sponsor
- ACADIA Pharmaceuticals Inc.
Psychosis
A Follow up Safety Study of Patients Who Participated in Previous Studies of the Drug Org 24448 (Study P05719)(COMPLETED)
This is a safety study evaluating the subjects who participated in previous Organon trials of the drug Org 24448. Patients will undergo a Screening visit, 1 or 2 Evaluation visits, and a possible Follow-Up period.
- Trial name
- NCT00780585
- Testing
- SCH 900460
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Auditory Verbal Hallucinations, Schizophrenia
Theta-Burst Transcranial Magnetic Stimulation for Treatment-Resistant Auditory Hallucinations
The goal of this clinical trial is to learn whether theta-burst transcranial magnetic stimulation (TBS), a non-invasive brain stimulation technique, can help reduce persistent auditory verbal hallucinations (hearing voices) in…
- Conditions
- Auditory Verbal Hallucinations, Schizophrenia, Schizoaffective Disorder, Psychotic Disorders
- Trial name
- NCT07902518
- Testing
- Theta-Burst Transcranial Magnetic Stimulation (TBS)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Psychosis, Schizophrenia
STEP-ED: Reducing Duration of Untreated Psychosis and Its Impact in the U.S.
The guiding questions for this study are: can a U.S. adaptation of a successful Scandinavian approach (TIPS) to early detection substantially reduce the duration of untreated psychosis (DUP) and improve outcomes beyond an…
- Trial name
- NCT02069925
- Testing
- Early Detection (ED), Usual Detection
- Where
- 2 sites in United States
- Volunteers
- 285 people
- Sponsor
- Yale University
Psychosis
Multiomic Diagnostics in Youth With Psychosis
Rady Children's Institute for Genomic Medicine seeks to understand the genomes and immune systems in 15 children and adolescents who are admitted to Rady Children's Hospital Child and Adolescent Psychiatry Service with psychotic…
- Trial name
- NCT05457140
- Testing
- Genetic: Genomic sequencing and molecular diagnostic results, if any., Phage display ImmunoPrecipiation Sequencing (PhIP-Seq)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Rady Pediatric Genomics & Systems Medicine Institute
Schizophrenia, Schizoaffective Disorder
Neurophysiological Studies in Schizophrenia and Psychiatric Disorders
The overall goal of this project is to identify intermediate phenotypes for psychosis across the schizophrenia and bipolar disorders boundary with implications for future genetic studies.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
- Trial name
- BSNIP (NCT01384604)
- Where
- United States
- Volunteers
- 1,189 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Schizophrenia, Schizophrenic Disorders
Open-label Study of Flexible-dose Paliperidone ER (Extended Release) to Treat Adolescent Schizophrenia.
The purpose of this open-label study is to evaluate the long-term (6-month) safety and tolerability of extended-release paliperidone, an atypical antipsychotic, given in flexible dosages to adolescents with schizophrenia.
- Conditions
- Schizophrenia, Schizophrenic Disorders, Psychotic Disorders, Dementia Praecox
- Trial name
- NCT00488319
- Testing
- Paliperidone ER
- Where
- 53 sites in United States, Belgium and 9 more
- Volunteers
- 400 people
- Sponsor
- Janssen Research & Development, LLC
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