Clinical trials: Non ST Elevation Myocardial Infarction (NSTEMI)
Myocardial Infarction
CMR for Prognosis Assessment in NSTEMI
The prognostic significance of cardiac magnetic resonance (CMR) derived parameters of myocardial and microvascular injury has not been fully elucidated yet in non-ST-Elevation myocardial infarction (NSTEMI) patients.
- Trial name
- NCT03516578
- Testing
- Cardiac magnetic resonance imaging
- Volunteers
- 314 people
- Sponsor
- Heart Center Leipzig - University Hospital
Peri-procedural Myocardial Infarction, Heart Failure Hospitalization
Clinical Evidence With Biomarker Confirmation for PPMI in PCI Clinical Trials Study
The goal of this prospective, multicenter, non-randomized observational study is to better identify and understand periprocedural myocardial injury among adults undergoing percutaneous coronary intervention (PCI) for stable…
- Conditions
- Peri-procedural Myocardial Infarction, Heart Failure Hospitalization, Mortality, Stable Angina Pectoris
- Trial name
- CEC-PPMI (NCT07848529)
- Testing
- Biomarker testing
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Baim Institute for Clinical Research
Coronary Heart Disease
After Eighty Study
The rationale of the present clinical trial is to study whether an invasive strategy in clinical stable patients over 80 years with NSTEMI/UAP may improve rates of death, reinfarction, stroke, need of urgent revascularisation…
- Trial name
- NCT01255540
- Where
- Norway
- Volunteers
- 492 people
- Sponsor
- Oslo University Hospital
Acute Coronary Syndromes
Does Optical Coherence Tomography Optimise Results of Stenting
Optical Coherence Tomography (OCT) is a recent imaging modality that yields cross-sectional images with a resolution 10 times greater than that of intravascular ultrasound (IVUS).
- Trial name
- DOCTORS (NCT01743274)
- Testing
- OCT
- Where
- 8 sites in France
- Volunteers
- 240 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Coronary Artery Disease
An Epidemiological Cohort Study of Acute Coronary Syndromes in The Greek Population. The PHAETHON Study
A nationwide registry of patients with acute coronary disease to evaluate epidemiological patient characteristics, medical management, implementation of invasive strategy, patient outcome and impact on quality of life in Greece.
- Trial name
- PHAETHON (NCT02420808)
- Where
- Greece
- Volunteers
- 800 people
- Sponsor
- Hellenic Cardiovascular Research Society
Acute Coronary Syndrome, Myocardial Infarction (MI)
Clinical Echocardiography and S' Wave for Early Recognition of Acute Coronary Syndrome in the Emergency Department, A Prospective Study
The goal of this prospective observational study is to assess the diagnostic accuracy of the tissue Doppler imaging (TDI) S' wave in detecting acute coronary syndrome (ACS) in adult patients presenting to the emergency department…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction (MI), Non-ST Elevation Myocardial Infarction, Unstable Angina
- Trial name
- CLEAR_ECHO (NCT06860997)
- Testing
- Tissue Doppler Imaging (TDI) S' Wave Echocardiography
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
ST Elevation Myocardial Infarction, Non-ST Elevation Myocardial Infarction
IVUS Versus FFR for Non-infarct Related Artery Lesions in Patients With Multivessel Disease and Acute MI
The aim of the study is to compare clinical outcomes between intravascular ultrasound (IVUS)-guided treatment decision versus fractional flow reserve (FFR)-guided treatment decision for non-infarct related artery stenosis in…
- Trial name
- FRAME-AMI2 (NCT05812963)
- Testing
- IVUS-guided PCI group, FFR-guided PCI group
- Where
- 2 sites in South Korea
- Volunteers
- 1,400 people
- Sponsor
- Samsung Medical Center
Myocardial Infarction, Acute
Korea Acute Myocardial Infarction Registry
This multicentre observational registry study, the Korea Acute Myocardial Infarction Registry (KAMIR-7), aims to improve long-term prognosis in Korean patients with acute myocardial infarction (AMI) by establishing and operating…
- Trial name
- KAMIR-7 (NCT07409441)
- Where
- 2 sites in South Korea
- Volunteers
- 20,000 people
- Sponsor
- Samsung Medical Center
Coronary Artery Disease, Coronary Syndrome
Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With (N)STEMI or Unstable Angina
The POLARSTAR study is an early safety and feasibility study to evaluate the performance and safety of the CryoTherapy System (CTS) for the treatment of coronary plaque lesions that are not obstructing blood flow but are at…
- Conditions
- Coronary Artery Disease, Coronary Syndrome, Cryotherapy Effect, Myocardial Infarction
- Trial name
- POLARSTAR (NCT05600088)
- Testing
- CryoTherapy System (CTS)
- Where
- 5 sites in Georgia, Lithuania
- Volunteers
- 24 people
- Sponsor
- Cryotherapeutics SA
Myocardial Infarction, STEMI
Breisgau PHENO-HEART MI
Coronary heart disease and its acute complication, myocardial infarction (MI), represent the leading causes of death in Europe and the United States.
- Conditions
- Myocardial Infarction, STEMI, NSTEMI
- Trial name
- NCT06166407
- Testing
- no intervention
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- University Hospital Freiburg
Coronary Artery Disease, Unstable Angina
Restore EF Observational Study
A multi-center, prospective, observational, non-interventional single arm, study of the intermediate-term clinical outcomes collected from electronic health records of high-risk patients which have previously undergone standard…
- Conditions
- Coronary Artery Disease, Unstable Angina, Angina, Stable, NSTEMI - Non-ST Segment Elevation MI
- Trial name
- NCT04648306
- Testing
- Prophylactic Impella support for a non-emergent PCI
- Where
- 21 sites in United States
- Volunteers
- 406 people
- Sponsor
- Abiomed Inc.
Coronary Artery Calcification, Ischemic Heart Disease
The Influence of Modifying Highly Calcified Coronary Lesions on Coronary Microcirculation
This is a prospective, single-center, three-arm study to evaluate the impact of severely calcified coronary lesions treatment on microvascular circulation.
- Conditions
- Coronary Artery Calcification, Ischemic Heart Disease, Non-ST-Segment Elevation Myocardial Infarction (NSTEMI), Coronary Artery Disease
- Trial name
- NCT06507449
- Testing
- Lithotripsy, Orbital atherectomy, High-pressure non-compliant balloon
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Silesia
Myocardial Infarction (MI), Heart Failure
Timing of Coronary Angiography in NSTEMI Complicated by Acute HF
Study objectives: To determine the optimal timing of coronary angiography (CAG) in patients with non-ST-segment elevation myocardial infarction (NSTEMI) complicated by acute decompensated heart failure (AHF).
- Trial name
- TIMING-AHF (NCT07002164)
- Testing
- Immediate coronary angiography, Delayed coronary angiography
- Where
- 20 sites in South Korea
- Volunteers
- 780 people
- Sponsor
- Chonnam National University Hospital
Cardiovascular Disease, Stable Angina
Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Stable Angina, NSTEMI and STEMI Undergoing PCI
Ticagrelor therapy has been shown to reduce the rates of cardiovascular events and all-cause mortality compared to clopidogrel therapy in patients with acute coronary syndromes (ACS).
- Conditions
- Cardiovascular Disease, Stable Angina, Myocardial Infarction, Coronary Artery Disease
- Trial name
- NCT02012140
- Testing
- ticagrelor
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- LifeBridge Health
Coronary Arteriosclerosis
Characteristics of Culprit Lesion and Changes in Plaque Composition. A Dual Energy Cardiac CT Study
Identifying patients who are at risk for a future myocardial infarction, is still one of the biggest challenges in cardiology. In this study the investigators will investigate culprit lesion in patients with NSTEMI and the…
- Trial name
- S-20130009 (NCT02639962)
- Testing
- Cardiac CT
- Where
- Denmark
- Volunteers
- 135 people
- Sponsor
- Odense University Hospital
Multivessel Coronary Artery Disease, Vessel Disease
Functional Testing Underlying Coronary Revascularisation
The objective of this trial is to compare the clinical outcomes and cost-effectiveness of 2 therapeutic strategies, one based on coronary angiography guidance and the other based on coronary angiography with fractional flow…
- Conditions
- Multivessel Coronary Artery Disease, Vessel Disease, Stable Angina, Unstable Angina or Stabilized Non-ST Elevated Myocardial Infarction
- Trial name
- FUTURE (NCT01881555)
- Testing
- invasive coronary angiography, Functional testing by fractional flow reserve measurement
- Where
- France
- Volunteers
- 941 people
- Sponsor
- Hospices Civils de Lyon
Coronary Artery Disease
BIOFLOW III Satellite-ELADIS Orsiro Stent System
This registry is a clinical evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT02029092
- Where
- 14 sites in Spain
- Volunteers
- 404 people
- Sponsor
- C.E.M. Biotronik, S.A.
Coronary Artery Disease, Myocardial Infarction
Compressive Elastic Dressing Versus TR Band
Radial approach is widely established in cardiac diagnostic and therapeutic treatments. It has been shown to decrease bleeding, vascular problems, and mortality rates when compared to the femoral approach.
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Angina, Unstable, Angina, Stable
- Trial name
- Band Vs Gauze (NCT05409716)
- Testing
- Compressive Elastic dressing for hemostasis in cardiac procedure using radial approach, Wristband TR band for hemostasis in cardiac procedure using radial approach
- Where
- 2 sites in Palestinian Territories
- Volunteers
- 400 people
- Sponsor
- An-Najah National University
Non-ST Elevation Myocardial Infarction
Initial CT Perfusion-Guided Strategy for Suspected NSTEMI
Non-ST elevation myocardial infarction (NSTEMI) is a relatively complex type of myocardial infarction, characterized by chest pain symptoms and elevated troponin levels.
- Trial name
- SMART (NCT06689267)
- Testing
- computed tomography myocardial perfusion, Invasive Coronary Angiography
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Shanghai Zhongshan Hospital
ACS - Acute Coronary Syndrome, NSTEMI - Non-ST Segment Elevation MI
MCG Discovery Study in Emergency Departments
This prospective discovery study is designed to demonstrate the feasibility of using an unshielded, mobile MCG device in an Emergency Department (ED) setting.
- Trial name
- NCT06095557
- Testing
- Sponsor MCG device
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- SB Technology, Inc.