Clinical trials: Non STEMI
Diabetes Mellitus, Type 2, NSTEMI - Non-ST Segment Elevation MI
Incidence of Major Cardiovascular Events in Diabetic Patients With ACS Undergoing Coronary Angioplasty and Treated With Clopidogrel 150 mg Versus 75 mg
Acute Coronary Syndrome (ACS) is triggered by the rupture of an atherosclerotic plaque that results in a platelet aggregation reaction in the coronary artery.
- Conditions
- Diabetes Mellitus, Type 2, NSTEMI - Non-ST Segment Elevation MI, Coronary Angioplasty
- Trial name
- IDASCOP 1 (NCT03329261)
- Testing
- Clopidogrel
- Where
- Tunisia
- Volunteers
- 167 people
- Sponsor
- Laboratoires Teriak
Non-ST-segment Elevation Myocardial Infarction
Study on High-sensitivity Troponin 0h/1h for Rapid Diagnosis of Non-ST-segment Elevation Myocardial Infarction in the Chinese Population
The purpose of the study is to establish a high-sensitivity troponin 0h/1h process for the diagnosis of patients suspected of NSTEMI for the Chinese population, obtain the inclusion and exclusion criteria for diagnosis of these…
- Trial name
- NCT03331549
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Beijing Anzhen Hospital
Acute Myocardial Infarction
Does Heme Oxygenase-1 Induction Ameliorate Cardiac Injury After Myocardial Infarction?
Rationale: A safety and dose defining study in which the investigators hypothesize that in patients with acute coronary syndrome without ST-elevation (NSTEMI) treatment with heme arginate results in better clinical outcome by…
- Trial name
- HAEM (NCT00483587)
- Testing
- Heme arginate
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- University Medical Center Groningen
ST Elevation Myocardial Infarction, Non ST Elevation Myocardial Infarction
Colchicine and Spironolactone in Patients with MI / SYNERGY Stent Registry
The CLEAR SYNERGY trial will study the long term effects of treatments following PCI to treat myocardial infarction. These treatments address both the culprit artery (PCI with SYNERGY stent) as well as the non-culprit arteries…
- Trial name
- CLEAR SYNERGY (NCT03048825)
- Testing
- Colchicine, Spironolactone, SYNERGY Bioabsorbable Polymer Drug-Eluting Stent
- Where
- 109 sites in United States, Australia and 12 more
- Volunteers
- 7,264 people
- Sponsor
- Population Health Research Institute
Acute Coronary Syndrome, NSTEMI - Non-ST Segment Elevation MI
Safety of Accelerated Rule-out Protocols in Patients Admitted With Chest Pain to a Crowded Chest Pain Unit (CPU)
The aim of this observational study registry is to assess the safety of a Non-ST-elevation myocardial infarction (STEMI) rapid rule-out strategy as proposed by European Guidelines in patients presenting with suspected acute…
- Trial name
- NCT03111862
- Testing
- NSTEMI Rule-Out according to hs-TnT
- Where
- Germany
- Volunteers
- 3,567 people
- Sponsor
- University Hospital Heidelberg
Coronary Artery Disease, Ischemic Heart Disease
Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial
This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions prior to implantation of drug-eluting stents (DES).
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Non ST Segment Elevation Myocardial Infarction
- Trial name
- ECLIPSE (NCT03108456)
- Testing
- Orbital Atherectomy, Balloon
- Where
- 104 sites in United States
- Volunteers
- 2,005 people
- Sponsor
- Abbott Medical Devices
Myocardial Reperfusion Injury
Role of Endothelin in Microvascular Dysfunction Following PCI for NSTEMI
Percutaneous coronary intervention (PCI) for acute coronary syndromes frequently fails to restore myocardial perfusion despite establishing epicardial vessel patency.
- Trial name
- BQ-123 (NCT00586820)
- Testing
- BQ-123
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Mayo Clinic
Acute Coronary Syndrome, Myocardial Infarction
OptimiZation Of Lipid Lowering Therapies Using a Decision Support System In Patients With Acute Coronary Syndrome.
The goal of this clinical trial is to compare implementation of a Decision Support System (DSS) - aligned to the 2019 ESC/EAS Guidelines - in addition to routine clinical care versus routine clinical care without availability of…
- Trial name
- ZODIAC (NCT05844566)
- Testing
- Decision Support System (DSS)
- Where
- 42 sites in Italy, Spain and 1 more
- Volunteers
- 1,139 people
- Sponsor
- Imperial College London
Peri-procedural Myocardial Infarction, Heart Failure Hospitalization
Clinical Evidence With Biomarker Confirmation for PPMI in PCI Clinical Trials Study
The goal of this prospective, multicenter, non-randomized observational study is to better identify and understand periprocedural myocardial injury among adults undergoing percutaneous coronary intervention (PCI) for stable…
- Conditions
- Peri-procedural Myocardial Infarction, Heart Failure Hospitalization, Mortality, Stable Angina Pectoris
- Trial name
- CEC-PPMI (NCT07848529)
- Testing
- Biomarker testing
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Baim Institute for Clinical Research
Myocardial Infarction
A Structuralised Sick-leave Program Compared to Usual Care Sick Leave Management in Patients After an Acute Myocardial Infarction
In this study the investigators aim at comparing the effect on quality of life and the cost-effectiveness of a structuralised sick-leave program compared to usual care sick leave management in patients after an acute non ST…
- Trial name
- NCT01108653
- Testing
- Usual care sick-leave management, Structuralised sick-leave program
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Acute Coronary Syndrome
MT1002 Phase II Study in ACS Patients With PCI
This is an open-label, sequential-dose escalation/de-escalation trial testing 3 dose levels of MT1002 in patients undergoing PCI due to ACS with NSTEMI.
- Trial name
- NCT04723186
- Testing
- MT1002 for Injection
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Shaanxi Micot Pharmaceutical Technology Co., Ltd.
Acute Myocardial Infarction, Non-ST Elevation Myocardial Infarction (nSTEMI)
Danish Trial of Beta Blocker Treatment After Myocardial Infarction Without Reduced Ejection Fraction
To determine whether long-term treatment with oral betablocker therapy after myocardial infarction in patient with no heart failure reduces the composite outcome of recurrent MI, all-cause mortality, revascularisation with…
- Conditions
- Acute Myocardial Infarction, Non-ST Elevation Myocardial Infarction (nSTEMI), ST Elevation Myocardial Infarction
- Trial name
- DANBLOCK (NCT03778554)
- Testing
- Metoprolol Succinate, Bisoprolol, Carvedilol
- Where
- Denmark
- Volunteers
- 2,760 people
- Sponsor
- Bispebjerg Hospital
Unstable Angina, NSTEMI
Dual Antiplatelet Therapy Tailored on the Extent of Platelet Inhibition
The purpose of this study is to evaluate the efficacy (reduction of major ischemic events at 6 and 12 months of follow-up) of a tailored clopidogrel therapy in patients with UA/NSTEMI undergoing PCI with stent implantation and…
- Trial name
- DANTE (NCT00774475)
- Testing
- comparison of different dosage of clopidogrel, doubled therapy
- Where
- Italy
- Volunteers
- 442 people
- Sponsor
- University of Florence
Acute Coronary Syndrome, Myocardial Infarction (MI)
Clinical Echocardiography and S' Wave for Early Recognition of Acute Coronary Syndrome in the Emergency Department, A Prospective Study
The goal of this prospective observational study is to assess the diagnostic accuracy of the tissue Doppler imaging (TDI) S' wave in detecting acute coronary syndrome (ACS) in adult patients presenting to the emergency department…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction (MI), Non-ST Elevation Myocardial Infarction, Unstable Angina
- Trial name
- CLEAR_ECHO (NCT06860997)
- Testing
- Tissue Doppler Imaging (TDI) S' Wave Echocardiography
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Vascular Access Complication, Coronary Artery Disease
Distal Radial Access for Coronary Procedures
Distal radial access (DRA) in the anatomical snuffbox (AS) is a relatively novel approach that can be considered an alternative to trans radial access (TRA) for coronary procedures.
- Conditions
- Vascular Access Complication, Coronary Artery Disease, STEMI, Non STEMI
- Trial name
- DISTAL (NCT06165406)
- Testing
- Distal radial access
- Where
- Spain
- Volunteers
- 2,000 people
- Sponsor
- Hospital Arnau de Vilanova
Myocardial Infarction, STEMI
Breisgau Pheno Heart Study
Coronary heart disease and its acute complication, myocardial infarction (MI), represent the leading causes of death in Europe and the United States.
- Conditions
- Myocardial Infarction, STEMI, NSTEMI
- Trial name
- NCT06166407
- Testing
- no intervention
- Volunteers
- 400 people
- Sponsor
- University Hospital Freiburg
Thromboembolism
Michelangelo - Oasis 5
Study Objectives PRIMARY OBJECTIVE: To evaluate whether fondaparinux is at least as effective as or superior to enoxaparin in preventing death, myocardial infarction or refactory ischemia up to Day 9 in the acute treatment of…
- Trial name
- NCT00139815
- Testing
- Fondaparinux, enoxaparin
- Volunteers
- 20,078 people
- Sponsor
- GlaxoSmithKline
Acute Myocardial Infarction, Non-ST Elevation Myocardial Infarction
Impact of Cardiac Rehabilitation Programs on Left Ventricular Remodeling After Acute Myocardial Infarction - the REHAB Trial
The aim of REHAB trial is to investigate the impact of early mobilization after AMI in reducing left ventricular remodeling, as assessed by cardiac magnetic resonance imaging.
- Conditions
- Acute Myocardial Infarction, Non-ST Elevation Myocardial Infarction, Systemic Inflammation, Ventricular Remodeling
- Trial name
- NCT04161378
- Testing
- Cardiac imaging, Laboratory analysis
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- Cardio Med Medical Center
Acute Myocardial Infarction
Study to Assess the Safety and Cardiovascular Effects of Autologous Adipose-Derived Stromal Cells Implantation In Patients During the Acute Recovery Phase of ST-Elevation Myocardial Infarction
The intent of this clinical study is to answer the questions: 1) Is the proposed treatment safe? and 2) Is treatment effective in improving cardiac function and clinical outcomes?
- Trial name
- Acute MI (NCT01974128)
- Testing
- ASC isolation and implantation
- Where
- United States
- Sponsor
- Ageless Regenerative Institute
Non-ST-elevation Myocardial Infarction, Multivessel Coronary Artery Disease
Complete Revascularization Versus Culprit Lesion Only PCI in NSTEMI
Prospective, randomized, controlled, multicenter, open-label trial to study whether multivessel percutaneous coronary intervention (PCI) is superior over culprit-lesion only PCI in patients with non-ST-segment elevation…
- Trial name
- CompleteNSTEMI (NCT05786131)
- Testing
- Culprit-lesion revascularization, Non-culprit-lesion revascularization
- Where
- 58 sites in Austria, Germany
- Volunteers
- 3,390 people
- Sponsor
- Leipzig Heart Science gGmbH