Clinical trials: Non Traumatic Spinal Cord Injury
Hemiplegia, Spasticity
Upper Limb Nerve Cryoneurolysis is Non Inferior to the Usual Care and Has Therapeutic Add Value in Dealing With Shoulder Pain and Functional Problems Caused by Spasticity and Motor Impairment
This trial is part of the spastiCRYO clinical research project. The primary objective of this clinical trial is to test the hypothesis: "Upper limb nerve cryoneurolysis is non inferior to the usual care and has therapeutic add…
- Conditions
- Hemiplegia, Spasticity, Shoulder Spasticity, Shoulder Stiffness
- Trial name
- spastiCRYO-UL (NCT06782464)
- Testing
- Treatment
- Where
- Luxembourg
- Volunteers
- 50 people
- Sponsor
- Centre National de Rééducation Fonctionnelle et de Réadaptation
Non Traumatic Spinal Cord Injury, Sub-Acute Rehabilitation
Functional Electrical Stimulation vs Transcutaneous Stimulation in Patients With Subacute Spinal Cord Injury
Cervical spinal cord injuries (SCI) are the most common form of spinal cord injuries within the veteran population. Losing arm function is a major concern with these injuries.
- Conditions
- Non Traumatic Spinal Cord Injury, Sub-Acute Rehabilitation, Spinal Cord Injury Cervical, Electric Stimulation Therapy
- Trial name
- NCT07911657
- Testing
- RTI Xcite, ExaStim
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Center for Veterans Research and Education
Spinal Cord Diseases, Spinal Cord Injuries
Long-term Paired Associative Stimulation as a Treatment for Incomplete Spinal Cord Injury of Non-traumatic Origin
The investigators have recently shown in incomplete SCI patients that long-term paired associative stimulation is capable of restoring voluntary control over some paralyzed muscles and enhancing motor output in the weak muscles…
- Trial name
- NCT03104803
- Testing
- long-term paired associative stimulation
- Where
- Finland
- Volunteers
- 5 people
- Sponsor
- Helsinki University Central Hospital
Spinal Cord Injuries
Reliability and Validity of the ISNCSCI in Patients With Non-traumatic Spinal Cord Lesions
Aim of the study is to assess the psychometric properties of the International Standards for Neurological Classification of Spinal Cord Injury in subjects with non traumatic lesions.
- Trial name
- NCT04949763
- Testing
- rehabilitation
- Volunteers
- 140 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Motor Disorders, Healthy
Non-invasive BCI-controlled Assistive Devices
Injuries affecting the central nervous system may disrupt the cortical pathways to muscles causing loss of motor control. Nevertheless, the brain still exhibits sensorimotor rhythms (SMRs) during movement intents or motor imagery…
- Conditions
- Motor Disorders, Healthy, Spinal Cord Injuries, Muscular Diseases
- Trial name
- NCT05183152
- Testing
- NMES Feedback, Visual Feedback, TESS
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Spinal Cord Stimulation, Electric Stimulation Therapy
Evaluating Safety and Feasibility of Transcutaneous Spinal Cord Stimulation Following Traumatic and Non-Traumatic Spinal Cord Injury: A Pilot Study
The study will be a non-randomized, non-blinded pilot study to analyze the safety and feasibility of a non-significant risk device, transcutaneous spinal cord stimulation.
- Conditions
- Spinal Cord Stimulation, Electric Stimulation Therapy, Traumatic Spinal Cord Injury, Cervical Myelopathy
- Trial name
- STIM (NCT06520020)
- Testing
- Transcutaneous Spinal Cord Stimulation (Tc-SCS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Francis Farhadi
Acute Spinal Cord Injury
Mean Arterial Blood Pressure Treatment for Acute Spinal Cord Injury
Current guidelines for the clinical management of acute spinal cord injury (SCI) recommend maintenance of mean arterial blood pressure (MAP) at 85 to 90 mmHg for the first seven days after SCI as a clinical option.
- Trial name
- MAPS (NCT02232165)
- Testing
- Hypotension avoidance, Induced hypertension
- Where
- 2 sites in United States, Canada
- Volunteers
- 17 people
- Sponsor
- University of Calgary
Spinal Cord Disease, Spinal Cord Injuries (Complete and Incomplete)
Spinal Cord Stimulation Combined With Motor Training in Non-Traumatic SCI: A Prospective Interventional Study
Interventional prospective longitudinal on the evaluation of spinal cord stimulation (SCS) assisted by motor rehabilitation training for restoring motor function in patients with non-traumatic spinal cord injury (SCI).
- Trial name
- Neuro-scs-002 (NCT07412808)
- Testing
- Spinal cord stimulation surgery (device implant) and motor rehabilitation
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Albano Luigi
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Spinal Cord Compression, Spinal Cord Injuries
Enhancing Recovery in Non-Traumatic Spinal Cord Injury
The investigators have spent the last decade uncovering unique metabolic and functional abnormalities in the brains of patients with spinal cord compression.
- Conditions
- Spinal Cord Compression, Spinal Cord Injuries, Cervical Spondylosis, Myelopathy Cervical
- Trial name
- NCT03320759
- Testing
- Occupational therapy rehabilitation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Western University, Canada