Clinical trials: Non Vital Teeth
Tooth Injuries, Endodontically Treated Teeth
Regenerative Endodontic Treatment of Traumatised Teeth
Aim: The aim of this prospective study was to evaluate the treatment outcomes of regenerative endodontic technique (RET) for the management of traumatised non-vital immature teeth in children.
- Trial name
- NCT03045185
- Testing
- RET using Ciprofloxacin 100mg, and Metronidazole 100mg.
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Pain, Postoperative
Comparison of Post-operative Pain Frequency
The objective of this study is: To compare the post-operative pain frequency after single visit root canal versus multiple visit root canal treatment in patients with non-vital teeth Post-operative pain is less frequent after…
- Trial name
- NCT04944589
- Testing
- ROOT CANAL TREATMENT
- Where
- Pakistan
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Fatima Memorial Hospital
Discolored Teeth
Effect on Periodontal Markers by Bleaching Intracoronal Technique
OBJECTIVES: The aim of this clinical randomized, double-blind clinical study was to assess the markers levels of RANKL IL-1B and OPGL, involved in the external cervical resorption as a primary outcome, and change color…
- Trial name
- BLEIC (NCT02718183)
- Testing
- Hydrogen Peroxide 35% (Opalescence Endo - Ultradent, USA), carbamide peroxide 37% (Whiteness Superendo, FGM, Brazil).
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chile
Resorption of Tooth or Root
Clinical & Radiographic Evaluation of LSTR in Non-vital Primary Molars Using Two Different Vehicles
LSTR will be done for primary teeth with significant root resorption needing non-vital pulp therapy to save such teeth for up to 12 months.
- Trial name
- LSTR (NCT05079802)
- Testing
- Double antibiotic paste mixed with chitosan nanoparticles, Double antibiotic paste mixed with propylene glycol
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Non-Vital Tooth
Turmeric Gel as Alternative Non-vital Pulpotomy Medicament in Primary Teeth
The purpose of this randomized controlled clinical trial is to use Turmeric gel as non-vital Pulpotomy medicament compared to Formocresol in primary teeth by evaluating its antibacterial effect against Streptococcus mutans and…
- Trial name
- NCT05801354
- Testing
- Turmeric Gel, Formocresol
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Lahore
Pain, Postoperative, Root Resorption
Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair
Management of non-vital primary molars is challenging due to the natural anatomy of primary teeth, patients' young age, and their behavior toward dental treatment.
- Conditions
- Pain, Postoperative, Root Resorption, Persistent Infection, Necrotic Pulp
- Trial name
- NCT06926322
- Testing
- Conventional double antibiotic paste of Metronidazole 500 mg plus Ciprofloxacin 500 mg mixed with propylene glycol, Double antibiotic paste of Metronidazole and Ciprofloxacin loaded chitosan-coated silver nanoparticles, chitosan-coated silver nanoparticles
- Where
- Egypt
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Non Vital Teeth, Persistent Symptomatic Apical Periodontitis
To Evaluate and Compare the Effect of Orthograde and Retrograde MTA Root End Filling After Periapical Surgery in Posteriors
To evaluate and compare the effect of orthograde and retrograde MTA root end filling on clinical, 2D and 3D radiographic success and quality of life after periapical surgery in posteriors- A Randomised Control Trial
- Trial name
- NCT07808424
- Testing
- Endodontic Micro-Surgery
- Where
- India
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontal Pocket, Tooth,Non Vital
Chlorhexidine Intracanal Medicament in Periodontal Healing in Concomitant Endo Perio Lesion With Communication
The aim of this prospective randomized controlled clinical trial is to evaluate the effectiveness of chlorhexidine intracanal medicament along with periodontal treatment in concomitant endodontic periodontal lesions with…
- Trial name
- NCT02627326
- Testing
- open flap debridement
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Immature Teeth
Apexification Treatment With MTA(Mineral Trioxide Aggregate) and Ca(OH)2
Ninety immature teeth with necrotic pulps and periapical lesions on patients (aged 16-40y) were treated with AT using MTA (45 teeth) or CH (45 teeth) between 2015 and 2018.
- Trial name
- MTA Ca(OH)2 (NCT03855501)
- Testing
- Mineral trioxide aggregate, Calcium hydroxide
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ege University
Pulpitis
Vital Pulp Therapy to Treat Irreversible Pulpitis
The purpose of this study is to demonstrate non-inferiority of pulpotomy treatment (with new endodontic bio-materials) as a new treatment with one-visit root canal therapy as reference treatment in pain relief and clinical and…
- Trial name
- VPT (NCT00748280)
- Testing
- One-visit root canal therapy, pulpotomy
- Where
- Iran
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Non-Vital Tooth
Allium Sativum Oil as Alternative Non-vital Pulpotomy Medicament in Primary Teeth
The purpose of this randomized controlled clinical trial is to use Allium sativum oil as non-vital Pulpotomy medicament compared to Formocresol in primary teeth by evaluating its antibacterial effect against Streptococcus mutans…
- Trial name
- NCT05801367
- Testing
- Formocresol, Allium Sativum Oil
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Lahore
Irreversible Pulpitis (toothache)
Garlic Oil As Root Filling Material in Primary Molars
The goal of this study is to test garlic oil mixed with zinc oxide as a potential root canal filling material of primary molars in children aged from four to eight years.
- Trial name
- NCT06755502
- Testing
- Garlic oil, Calcium Hydroxide, Iodoform, paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mineral Trioxide Aggregate
Clinical and Radio-graphic Evaluation of Non-staining Bio-active Bio-ceramic (Neo MTA 2) in Revascularization
The study will compare the clinical and radio-graphic performance of newly introduced non-staining bio-active bio-ceramic (Neo MTA 2) versus White MTA used as coronal plug material in revascularization of non-vital immature…
- Trial name
- NCT06637761
- Testing
- NeoMTA2, WMTA
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulp Necroses
Revascularization of Immature Anterior Necrotic Teeth
The object of this study is to compare the effect of Calcium Hydroxide and Di-antibiotic paste as intracanal disinfectants in the 1st visit of revascularization of necrotic immature permanent anterior teeth.
- Trial name
- NCT03504332
- Testing
- intracanal disinfection in revascularization
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulp Necrosis, Apexification
Evaluation the Effect of Using of Apical Matrix With Apexification Procedure on Apical Healing of Necrotic Immature Teeth
This study was conducted to evaluate the effect of the use of apical matrix, with Mineral Trioxide Aggregate (MTA) or calcium hydroxide Ca(OH)2 Apexification on apical healing and calcific barrier formation of immature teeth with…
- Trial name
- NCT03849222
- Testing
- Apexification, MTA, Ca(OH)2
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Regenerative Endodontic Procedures, Necrotic Pulp
Treated Dentine Matrix and Platelet Rich Fibrin in Induction of Root Formation of Non-Vital Immature Permanent Teeth
This study will be conducted to clinically evaluate the efficacy of human treated dentine matrix paste and Platelet rich fibrin (PRF) in induction of root formation of non-vital immature permanent teeth.
- Trial name
- NCT05775081
- Testing
- Regenerative endodontic procedues
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Necrotic Pulp
Incidence of Post-Operative Pain After Single Visit Root Canal Treatment in Necrotic Teeth Using Two Different Rotary Systems (Protaper Nex t& Neolix File)
this prospective in vivo randomized clinical is to evaluate the post operative pain (incidence ,degree and duration) with multiple full rotation file (protaper next ®) and single full rotation file (Neolix®) in treating maxillary…
- Trial name
- NCT03059290
- Testing
- neolix file
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Attachment Loss, Tooth,Non Vital
Immediate Verses Delayed Surgical Periodontal Therapy After Endodontic Treatment in Endo Perio Lesion With Communication
The aim of the study is to conduct a prospective randomized clinical trial to evaluate the effect of immediate and delayed surgical periodontal therapy after non-surgical endodontic treatment on periodontal healing of the…
- Trial name
- NCT02630745
- Testing
- Immediate periodontal surgery, Delayed periodontal surgery
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Tooth, Deciduous
3Mixstatin ,Tri-Antibiotic Mix & Simvastatin in the Treatment of Primary Molars
The aim of this study is to determine whether the success rate of pulp therapy undergone on primary molars with signs and symptoms of odontogenic infection that may render them indicated for extraction will improve with the use…
- Trial name
- NCT03585751
- Testing
- Pulpectomy for primary molars + triple antibiotic mix, Pulpectomy for primary molars + 3mixstatin, Pulpectomy for primary molars + simvastatin
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Discoloration
A Comparative Study Between the Efficacy of Diode Laser and Nano-chitosan Gel on Activation of Non-vital in- Office Bleaching Agent
The growing demand for white smile between patients has increased over recent years, the development of techniques and improvement of materials permits searching for beautiful natural smile.
- Trial name
- NCT06782087
- Testing
- nano chitosan
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology