Clinical trials: Non-Adherence, Medication
Atrial Fibrillation, Medication Adherence
Use of Electronic Personal Health Records to Improve Medication Adherence
The purpose of this pilot study is to examine the use of a personal health record to improve medication adherence among patients with non-valvular atrial fibrillation taking dabigatran for primary prevention of embolic stroke.
- Trial name
- NCT03018197
- Testing
- Medication Education
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Parkview Health
HIV Infections, Depression
Task Shifting to Treat Depression and HIV Medication Nonadherence in Low Resource Settings
A hybrid effectiveness-efficacy trial to evaluate a stepped care task shifted intervention to treat depression and HIV medication nonadherence in low resource settings in rural Zimbabwe.
- Trial name
- NCT04018391
- Testing
- Stepped care for nonadherence and depression, Enhanced Usual Care
- Where
- Zimbabwe
- Volunteers
- 280 people
- Sponsor
- King's College London
Atrial Fibrillation, Medication Adherence
Determination of Rates and Reasons for Non-Adherence to Anti-Arrhythmic Therapy for Atrial Fibrillation
The purpose of this study is to determine if follow-up by a pharmacist over the telephone improves adherence and short term clinical outcomes in the patient with atrial fibrillation prescribed an oral anti-arrhythmic medication.
- Trial name
- NCT01513031
- Testing
- Education and telephone follow-up
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Creighton University
Health Education
Clinical Guidance for Proper Treatment of Unexplained Resistant Hyperprolactinemia.
Many women despite being well-treated in proper dose, with proper drug and for proper duration, may not respond to different forms of prolactin normalizing drugs.
- Trial name
- NCT04262024
- Testing
- cabergoline 1.5-2 mg/week).orally daily for 1 month plus health education, cabergoline 1.5-2 mg/week).orally daily for 1 month without health education
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Woman's Health University Hospital, Egypt
Schizophrenia; Psychosis, Remission
Effects of an Interpersonal Communication Skills Training Program on Medication Adherence of Schizophrenic Patients
This quasi-experimental two-group pretest-posttest study examined the effects of an interpersonal communication skills training program on medication adherence in patients with schizophrenia, measured at pre-intervention…
- Conditions
- Schizophrenia; Psychosis, Remission, Non-Adherence, Medication
- Trial name
- NCT07165821
- Testing
- Interpersonal Communication Skills Training Program, Usual care
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Suranaree University of Technology
Musculoskeletal Diseases, Rheumatoid Arthritis
Improving Beliefs About Medication in Patients With Rheumatoid Arthritis
The purpose of this study is to determine if a short motivational patient-centered intervention for non-adherent patients is more successful in improving beliefs about medication (and adherence) compared to a usual care control…
- Trial name
- NCT00968266
- Testing
- Patient-centered group intervention
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Sint Maartenskliniek
Medication Non Adherence, Polypharmacy
Tailored Medication Management Intervention
Successful medication management is an essential instrumental activity of daily living (IADL) for older adults with polypharmacy; however, between 40%-70% of older adults fail to take their medications as prescribed.
- Trial name
- NCT04717297
- Testing
- Medication Management Remote Intervention, Waitlist Control, Medication Management In-Person Intervention
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Washington University School of Medicine
Level of Digital Game Addiction, Level of Cyberbullying
Digital Game Addiction and Cyberbullying in Adolescents
With the widespread use of technology and internet, digital game addiction and cyberbullying behaviors have increased among adolescents. Effective interventions are needed to prevent these behaviors.
- Trial name
- NCT06241989
- Testing
- health education supported by motivational interviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Gazi University
Attention Deficit Disorder, Attention Deficit Disorder (ADD)
The Primary Objective of This Study is to Determine Whether Positively Framed Information (PFI) on Side Effects, Compared to Negatively Framed and Extensive Information (NFI) Can Reduce the Number and Severity of Reported Adverse Events Caused by ADHD Medication in Children Aged 7 to 17 Years.
The goal of this randomized controlled care evaluation is to determine whether positively framed and concise information (PFI), compared to negatively framed and extensive information (NFI) about adverse events can reduce the…
- Conditions
- Attention Deficit Disorder, Attention Deficit Disorder (ADD), Attention Deficit Disorder with Hyperactivity, ADHD
- Trial name
- NOVA (NCT06797570)
- Testing
- Communication Strategy for Side Effect Counseling in ADHD Treatment
- Volunteers
- 130 people
- Sponsor
- St. Antonius Hospital
Medication Non-adherence, Stent Thrombosis
Patterns of Non-Adherence to Dual Anti-Platelet Regimen In Stented Patients
The purpose of this observational research study is to determine when and why patients discontinue, interrupt, or disrupt the regimen of anti-platelet medications prescribed following stent implantation, and to examine the…
- Trial name
- PARIS (NCT00998127)
- Where
- 15 sites in United States, France and 3 more
- Volunteers
- 5,031 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hypertension, Uncontrolled Hypertension
Addressing Medication Non-adherence in Patients With Poorly Controlled Hypertension Using Urine Mass Spectrometry
Hypertension is the single largest contributor to cardiovascular disease and death. While adequate control of hypertension reduces risk of disease, many patients have uncontrolled hypertension.
- Conditions
- Hypertension, Uncontrolled Hypertension, Non-Adherence, Medication
- Trial name
- ADURINE (NCT06938633)
- Testing
- mass spectrometry analysis
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- Changi General Hospital
Osteoarthritis, Rheumatoid Arthritis
Observational Study on Non-steroid Anti-inflammatory Drugs (NSAIDs) Treated Patients With Arthritic Disorder
The aim of this study is to find out how patients with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis receiving NSAID-therapy are treated and managed by their doctor in usual clinical practice, how patients…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis
- Trial name
- EVIDENCE (NCT01176682)
- Where
- 244 sites in Belgium, France and 10 more
- Volunteers
- 1,149 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Type 2, Hypertension
An Analysis to Assess Non-adherence in People With Type 2 Diabetes
Non-adherence is defined as: "the extent to which a person's behaviour - taking medication, following a diet, and/or executing lifestyle changes, corresponds with agreed recommendations from a health care provider".
- Conditions
- Diabetes Mellitus, Type 2, Hypertension, Medication Adherence
- Trial name
- NCT05256875
- Testing
- chemical adherence test, medication adherence questionnaire, pharmacy refill rate
- Where
- 2 sites in United Kingdom
- Volunteers
- 90 people
- Sponsor
- University of Leicester
Psychotic Disorders, Schizophrenia
A Concierge Model of CAE Plus LAI in Individuals With Schizophrenia at Risk for Treatment Non-adherence and Homelessness
This is a prospective study using a concierge model of customized adherence enhancement and long-acting injectable antipsychotic (CAL-Concierge) in 30 individuals with schizophrenia or schizoaffective disorder at risk for…
- Conditions
- Psychotic Disorders, Schizophrenia, Schizoaffective Disorder, Medication Adherence
- Trial name
- CAL-C (NCT02085447)
- Testing
- CAE-L
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University Hospitals Cleveland Medical Center
HIV
A Pilot Study to Examine Efficacy of Peer Mentoring in Promoting Medication Adherence Among People Living With HIV/AIDS
This study aims to investigate the effectiveness of an in-person peer mentoring and health literacy intervention on improving medication adherence, HIV-1 viral load, CD4+ T lymphocyte counts, and HIV medical appointment…
- Trial name
- NCT02025322
- Testing
- Peer Mentoring
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Jury Candelario
Drug Resistance
Aspirin and Clopidogrel Resistance Study
Resistance to antiplatelet drugs (aspirin, clopidogrel) is a recognized phenomenon with a prevalence from 17% to 35%. Resistance as detected by in vitro tests such as Multiple Electrode Aggregometry (MEA) has been shown to…
- Trial name
- NCT01039480
- Where
- Switzerland
- Volunteers
- 82 people
- Sponsor
- University Hospital, Basel, Switzerland
Delivery of Health Care, Genetic Testing
Supporting Just-In-Time Consent for Prenatal Screening: The INFORM Study
This clinical trial is about prenatal genetic screening. It will test an intervention to help people make decisions about screening. The intervention is a short set of information cards about screening.
- Conditions
- Delivery of Health Care, Genetic Testing, Humans, Pregnancy
- Trial name
- NCT07557303
- Testing
- Mobile-based Educational Intervention
- Where
- 3 sites in United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Medication Adherence, Medication Nonadherence
Identifying Reasons for Non-adherence in Patients With Multi-morbidity
The study will be carried out during pharmacist-conducted medication reconciliation. The pharmacist will ask how the patient has been taking the prescribed medicines and whether any over-the-counter medicines and food supplements…
- Conditions
- Medication Adherence, Medication Nonadherence, Chronic Disease
- Trial name
- NCT05167578
- Testing
- Medication reconciliation
- Where
- Finland
- Volunteers
- 250 people
- Sponsor
- Helsinki University Central Hospital
Heart Failure
Study of Reminding to Improve Medication Adherence in Heart Failure
This study is being done to look at how people manage their heart failure. The investigators are testing two medication reminder systems and the investigators want to know which one people like better.
- Trial name
- Heart iRx (NCT01463267)
- Testing
- iPhone or pillbox, Non-reminding
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kent State University
HIV Infections
Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings
This study compared 3 different three-drug combinations in HIV infected individuals starting their first HIV treatment regimens.
- Trial name
- PEARLS (NCT00084136)
- Testing
- Atazanavir, Didanosine (enteric-coated), Efavirenz
- Where
- 42 sites in United States, Brazil and 7 more
- Volunteers
- 1,571 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections