Clinical trials: Non-Adherence, Medication
Steatohepatitis, Nonalcoholic, Steatosis
Nutritional Intervention IN Nash NON-ALCOHOLIC (NAFLD).
The goal of this randomized clinical trial with adults is to discuss the effectiveness of the nutritionist's educational interventions in users diagnosed with NAFLD, compared to the usual medical follow-up of users treated at the…
- Conditions
- Steatohepatitis, Nonalcoholic, Steatosis, Liver Diseases, Steatohepatitis
- Trial name
- NUTRINAFLD (NCT05946330)
- Testing
- NUTRITIONAL EDUCATIONAL INTERVENTION IN FATTY LIVER DISEASE NON-ALCOHOLIC (NAFLD).
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Universidade Federal do Paraná
Hypertension, Primary Hypertension
Effectiveness of SMS Reminders of Blood Pressure-lowering Drugs Intake
By conducting the SPPA trial we try to find out, whether personalized Short Message Service (SMS) reminders of blood pressure-lowering medication can effectively increase patients' adherence to blood pressure-lowering medication.
- Conditions
- Hypertension, Primary Hypertension, Non-Adherence, Medication, Non-Adherence, Patient
- Trial name
- SPPA (NCT03105687)
- Testing
- SMS reminders of medicines intake
- Where
- 24 sites in Slovakia
- Volunteers
- 300 people
- Sponsor
- Comenius University
HIV-1-infection, Non-Adherence, Medication
Outcomes of the PLHIV With Suboptimal Viral Suppression to Injectable Long-acting Antiretrovirals
This study aims to determine whether people living with HIV (PLHIV) with suboptimal medical adherence can achieve better viral suppression with long-acting antiretrovirals (LA) compared to all-oral antiretrovirals.
- Trial name
- SUPLA (NCT06507059)
- Testing
- cabotegravir/rilpivirine (600mg/ 900mg), Antiretroviral Combinations
- Where
- 4 sites in Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Atrial Fibrillation, Medication Adherence
Adherence and Coagulation Assays in Dabigatran-treated Patients With Atrial Fibrillation
In patients with non-valvular atrial fibrillation treated with dabigatran etexilate, the level of adherence will be measured using a questionnaire, the Danish National Prescription Registry and pillcount and will be related to…
- Conditions
- Atrial Fibrillation, Medication Adherence, Blood Coagulation Tests, Anticoagulants; Circulating, Hemorrhagic Disorder
- Trial name
- ARCADE (NCT03280368)
- Testing
- Bloodtest, Questionnaires
- Where
- Denmark
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Hospitalsenheden Vest
Osteoporosis, Postmenopausal, Osteoporosis, Steroid Induced
Adherence to Osteoporosis Treatment and Physicians' Perception Regarding Osteoporosis Medication
This is a study aiming to investigate a possible correlation between the parameters affecting the physicians' therapeutic choice with the patients' overall adherence to osteoporosis treatment.
- Trial name
- IASIS (NCT02472782)
- Testing
- Teriparatide
- Where
- Greece
- Volunteers
- 851 people
- Sponsor
- 251 Hellenic Air Force & VA General Hospital
Gastrointestinal Hemorrhage, Ulcer
Gastroprotective Agent Compliance in Patients at Risk Suffering From a Gastrointestinal(GI) Ulcer
The purpose of this study is to assess gastroprotective agent compliance in patients at risk suffering from a gastrointestinal bleeding ulcer or a symptomatic ulcer with NSAID.
- Trial name
- NCT01215058
- Volunteers
- healthy volunteers welcome
- Sponsor
- AstraZeneca
Medication Adherence, End Stage Renal Failure on Dialysis
Prevalence of Non-adherence to Medication Among Patients on Chronic Hemodialysis
Background: Non-adherence to medication among patients on chronic hemodialysis compromises treatment effects and results in increased morbidity, mortality and extensive costs to the healthcare system.
- Trial name
- NCT03897231
- Testing
- questionnaire
- Where
- Denmark
- Volunteers
- 385 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Opiate Addiction, Medication Non-adherence
Using Artificial Intelligence To Monitor Medication Adherence in Opioid Replacement Therapy
This study uses an artificial intelligence platform to automatically confirm medication ingestion. The Health Insurance Portability and Accountability Act (HIPAA)-compliant platform can be downloaded as an 'app' onto any…
- Conditions
- Opiate Addiction, Medication Non-adherence, Addiction, Opioid Dependence
- Trial name
- NCT02243670
- Testing
- AiCure monitoring and intervention
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- AiCure
Bipolar Disorder, Medication Adherence
CAE Plus LAI in Individuals With Bipolar Disorder at Risk for Treatment Non-adherence (BD-CAEL)
This is a prospective study using customized adherence enhancement (CAE) and long-acting injectable (LAI) antipsychotic in 30 individuals with bipolar disorder (BD) at risk for treatment non-adherence.
- Conditions
- Bipolar Disorder, Medication Adherence, Medication Non Adherence
- Trial name
- NCT03408873
- Testing
- Abilify Maintena, Customized Adherence Enhancement (CAE)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Martha Sajatovic
Pain, Postoperative, Analgesics, Opioid
Evaluation of Abdominal Wall Block With Liposomal Bupivacaine for Post-Operative Analgesia in Donor Nephrectomy
A blinded randomized control trial in living kidney donors. The study group will receive a liposomal bupivacaine Trans Quadratus Lumborum (TQL) block after the induction of general anesthesia.
- Conditions
- Pain, Postoperative, Analgesics, Opioid, Analgesics, Non-Narcotic, Physiological Effects of Drugs
- Trial name
- NCT03294109
- Testing
- Abdominal wall block with liposomal bupivicaine
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Bipolar Disorder, Non-Adherence, Medication
Using mHealth to Improve Adherence and Reduce Blood Pressure in Individuals With Hypertension and Mood Disorders
This proposed 2-stage randomized controlled trial (RCT) will evaluate a personalized patient-centered adherence intervention iTAB-CV + Self-Monitoring (iTAB-CV + SM) vs.
- Conditions
- Bipolar Disorder, Non-Adherence, Medication, Hypertension, Major Depressive Disorder
- Trial name
- iTAB-CV RCT (NCT04675593)
- Testing
- iTAB-CV, Self-Monitoring
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Case Western Reserve University
Breast Neoplasms, Prostatic Neoplasms
Study to Investigate Adherence of Patients to Clodronate (Bonefos) Treatment
Adherence (or compliance with) a medication regimen is generally defined as the extent to which patients take medication as prescribed by their health care providers.
- Conditions
- Breast Neoplasms, Prostatic Neoplasms, Multiple Myeloma, Osteolysis
- Trial name
- BONA (NCT01198457)
- Testing
- Clodronate (Bonefos, BAY94-8393)
- Where
- Czechia
- Volunteers
- 147 people
- Sponsor
- Bayer
CHF - Congestive Heart Failure
Digital Outreach for Heart Failure Adherence
The goal of the ADHERE-HF study is to evaluate whether care-embedded, operationally delivered digital outreach improves medication refill, adherence, and clinical outcomes among adults with heart failure who are overdue for a…
- Trial name
- ADHERE-HF (NCT07831538)
- Testing
- Digital Outreach
- Where
- United States
- Volunteers
- 13,714 people
- Sponsor
- Kaiser Permanente
Arterial Hypertension, Medication Nonadherence
Feasibility of a Program on a Nurse-led Telephone 6-month-follow-up for Uncontrolled Hypertensive Women
This study evaluate the feasibility of a 6-month personalized support program for hypertensive and non-observant women, led by nurses by telephone follow-up.
- Trial name
- PreDynamiques (NCT03963934)
- Testing
- Program on a nurse-led telephone 6-month-follow-up for uncontrolled hypertensive women: a patient-tailored intervention
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Mme Edith DAUCHY
Polycystic Ovary Syndrome, Overweight
Stress Reduction for Overweight or Obese Women Either With Polycystic Ovary Syndrome (PCOS) or Without PCOS (Non-PCOS)
The purpose of this study is to determine the effects of stress reduction on glucose, blood pressure, quality of life and overall health and well-being in overweight or obese women, either with Polycystic Ovary Syndrome (PCOS) or…
- Conditions
- Polycystic Ovary Syndrome, Overweight, Obesity, Stress, Physiological
- Trial name
- NCT01464398
- Testing
- Stress reduction, Stress reduction with Health education
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Milton S. Hershey Medical Center
Metastatic Renal Cancer, Stage III Renal Cell Cancer
Safety and Compliance of Renal Cancer Patients Treated by Non-IV Drugs
Generally, in the trials, an observant patient is described as correctly taking 90 to 100% of the prescribed doses. Here, the 80% compliance rate will be the cut-off between observant and non-observant patients.
- Trial name
- TOPTACOS (NCT03630692)
- Testing
- observance of oral drug treatment
- Where
- 14 sites in France
- Volunteers
- 158 people
- Sponsor
- Institut Cancerologie de l'Ouest
Parkinson Disease
Study of Comprehension and Execution of Medication Prescriptions in Parkinsonian Patients and Healthy Volunteers
Many patients with Parkinson's disease (Pd) don't respect medication prescriptions. Non-adherence is caused by several factors among which three play an important role: treatment complexity, cognitive decline, and…
- Trial name
- TACTIPARK (NCT03976505)
- Testing
- reading a table format prescription on a touch screen, reading a textual format prescription on a touch screen, filling a virtual pillbox displayed on the screen as prescribed in the prescription
- Where
- France
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Transplant;Failure,Kidney, Transplant; Failure, Liver
Leveraging Technology to Improve Medication Adherence in Youth With Kidney or Liver Transplant
Can the investigators create an effective way to improve adherence to immunosuppressant medication and reduce rejection, graft loss, and death in adolescents and young adults who have undergone kidney or liver transplantation?…
- Conditions
- Transplant;Failure,Kidney, Transplant; Failure, Liver, Adherence, Medication, Adherence, Patient
- Trial name
- NCT05613010
- Testing
- mHealth Messaging Intervention Group
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Johns Hopkins University
Diabetes Mellitus, Type 2
mHealth Skill Enhancement Plus Phone CBT for Type 2 Diabetes Distress Medication Nonadherence: Pilot Study
This is a pilot study examining the clinical effects of a brief Cognitive Therapy phone approach augmented with a CBT smartphone app geared towards patients with type 2 diabetes patients in poor control.
- Trial name
- NCT02081586
- Testing
- CBT, Smartphone app, Standard Diabetes Care at PCP
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Pittsburgh
Type 2 Diabetes Mellitus, Medication Adherence
STUDIIO-Diabetes Pilot: STUdy of Drug Insurance to Improve Outcomes of Diabetes
Canada is the only country with a universal health insurance system that does not provide coverage for prescription drugs to all residents. One-third of working-age Canadians have no insurance.
- Conditions
- Type 2 Diabetes Mellitus, Medication Adherence, Medication Compliance, Medication Nonadherence
- Trial name
- NCT03804905
- Testing
- No-cost Medications
- Volunteers
- 144 people
- Sponsor
- Sunnybrook Health Sciences Centre