Clinical trials: Non-Insulin Dependent
Diabetes Mellitus, Non-Insulin-Dependent
Effectiveness and Cost-effectiveness of the Diabetes Integrated Care Breakthrough Collaborative
The study tests whether implementing professional evidence-based guidelines and best practices for diabetes care -through participation of multidisciplinary teams in a Breakthrough collaborative- results in an improvement of…
- Trial name
- NCT00160017
- Testing
- Breakthrough collaborative
- Where
- 52 sites in Netherlands
- Volunteers
- 1,861 people
- Sponsor
- Radboud University Medical Center
Diabetes Mellitus Non-insulin-dependent
The Effect of Sitagliptin in Type 2 Diabetes Mellitus With Inadequate Glycemic Control (MK0431-118)
to assess the effect of treatment with Sitagliptin (MK0431) on HbA1c (Hemoglobin A1c) and the safety and tolerability of Sitagliptin.
- Trial name
- NCT00832624
- Testing
- sitagliptin
- Volunteers
- 10 people
- Sponsor
- Merck Sharp & Dohme LLC
Atherosclerosis, Cardiovascular Diseases
Action to Control Cardiovascular Risk in Diabetes (ACCORD)
The purpose of this study is to prevent major cardiovascular events (heart attack, stroke, or cardiovascular death) in adults with type 2 diabetes mellitus using intensive glycemic control, intensive blood pressure control, and…
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Hypercholesterolemia, Hypertension
- Trial name
- ACCORD (NCT00000620)
- Testing
- Anti-hyperglycemic Agents, Anti-hypertensive Agents
- Where
- 7 sites in United States, Canada
- Volunteers
- 10,251 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Diabetes Mellitus, Non-Insulin-Dependent
A Pilot Study on Effect of SKY on Psychosocial Parameters of Type 2 Diabetic Patients After a 6 Days
The purpose of this study is to determine whether Sudarshan Kriya Yoga intervention has effect on the quality of life , anxiety and depression of Type 2 Diabetic Patients.
- Trial name
- NCT02661906
- Testing
- SKY
- Where
- Kuwait
- Volunteers
- 24 people
- Sponsor
- Dasman Diabetes Institute
Metabolic Syndrome, Diabetes Mellitus, Non-Insulin-Dependent
Effect of Lycopene and Isoflavones on Glucose Metabolism
Type 2 diabetes mellitus (DM2) is a growing social health problem world-wide, in particular with respect to its contribution to cardiovascular disease.
- Trial name
- NCT01377961
- Testing
- Screening, OGTT, Anthropometrics and Blood pressure
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Diabetes Mellitus, Non-Insulin-Dependent, Glucose Intolerance
Diabetes Prevention Program
The Diabetes Prevention Program is a nationwide clinical study to answer the question: Can Type 2 diabetes (also called noninsulin-dependent or adult-onset diabetes) be prevented or delayed? The study has recruited volunteers…
- Trial name
- NCT00004992
- Testing
- Intensive lifestyle, Metformin
- Where
- United States
- Volunteers
- 3,234 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Macrosomia, Induction of Labour
Induction of Labour for LGA fœtus in Women Without Insulin-treated Diabetes.
A french study published in 2015 (DAME) showed a decrease of shoulder dystocia and an increase of spontaneous vaginal delivery when the non insulin-treated diabetes patients with large-for-date fetus were induced.
- Conditions
- Macrosomia, Induction of Labour, Non-insulin-dependent Diabetes
- Trial name
- NCT03355040
- Testing
- induction of labour
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Diabetic Nephropathy
Drugs for High Blood Pressure and High Cholesterol in American Indians With Type 2 Diabetes
OBJECTIVES: I. Establish a long-term working relationship between clinical investigators and the Minnesota American Indian community. II.
- Trial name
- NCT00004266
- Testing
- Lisinopril, Nifedipine, Simvastatin
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NSCLC Stage II, NSCLC Stage III
Efficacy of Anti-CTLA-4 Antibody Combined With Sintilimab and Chemotherapy as Neoadjuvant Therapy for Resectable Stage II-III Non-Small Cell Lung Cancer
This study aims to evaluate the major pathologic response (MPR) rate of neoadjuvant therapy with sintilimab (PD-1 inhibitor) + IBI310 (anti-CTLA-4 antibody) + chemotherapy, and to assess the efficacy of this treatment strategy in…
- Trial name
- NCT07410975
- Testing
- sintilimab+IBI310+chemotherapy
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Diabetes Mellitus, Non-Insulin-Dependent, Erectile Dysfunction
Evaluation of Advanced Glycation End-products (AGE) and the Erectile Dysfunction (DE) in Diabetic Patients
In diabetics there is an abnormally increased production of AGEs due to hyperglycemia. An association was shown between AGE measured by biopsy (invasive) and DE patients with diabetes (increase of AGE level in the corpora…
- Trial name
- APGADEPD (NCT02770235)
- Testing
- DE assessment, AGE measurement
- Where
- France
- Volunteers
- 97 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Non-Insulin-Dependent Diabetes Mellitus
AVANDAMET Versus Metformin And Sulphonylurea In People With Poorly Controlled Type 2 Diabetes
This study compares the effects of Avandamet (rosiglitazone maleate/metformin) treatment and metformin plus sulphonylurea treatment in overweight people with type 2 diabetes.
- Trial name
- NCT00359112
- Testing
- metformin, sulphonylurea, Avandamet
- Where
- 142 sites in Belgium, France and 9 more
- Volunteers
- 544 people
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus, Non-Insulin-Dependent
Clinical Study on Sitagliptin for Assessment of Glucose-lowering Effects (0431-045)
A clinical study determines the safety and efficacy of sitagliptin (MK0431) in patients with Type 2 diabetes mellitus who have inadequate glycemic control on diet/exercise therapy
- Trial name
- NCT00758069
- Testing
- sitagliptin phosphate, Comparator: Sitagliptin
- Volunteers
- 80 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus, Type 2
Efficacy and Safety of Alogliptin Plus Metformin in Patients With Type 2 Diabetes
The purpose of this study is to evaluate the safety and effectiveness of alogliptin combined with metformin, once daily (QD) or twice daily (BID), in participants with Type 2 Diabetes.
- Trial name
- AM7D (NCT01023581)
- Testing
- Alogliptin, Metformin
- Where
- 201 sites in United States, Czechia and 11 more
- Volunteers
- 784 people
- Sponsor
- Takeda
Cardiovascular Diseases, Heart Diseases
Mechanisms of Pro-Thrombosis in Diabetes Mellitus -- Ancillary to BARI 2D
To determine the effect of the method of hyperglycemic management on pro- thrombotic potential in diabetic subjects.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Diabetes Mellitus, Non-insulin Dependent, Coronary Disease
- Trial name
- NCT00041405
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Atherosclerosis
MRI Derived Organ & Tissue Mass Changes With Weight Loss - Ancillary to Look AHEAD
To investigate the composition and nature of weight loss and weight maintenance during the Look AHEAD trial. Also, to model changes in resting energy expenditure and changes in cardiac structure and function associated with…
- Conditions
- Cardiovascular Diseases, Atherosclerosis, Obesity, Diabetes Mellitus, Non-insulin Dependent
- Trial name
- NCT00031200
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Coronary Disease
Lifestyle Management for Women With CHD and NIDDM
To develop and evaluate a comprehensive lifestyle self-management (CLSM) program (low-fat vegetarian diet, smoking cessation and stress management training) for postmenopausal women with coronary heart disease and Type II…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Diabetes Mellitus, Non-insulin Dependent
- Trial name
- NCT00005441
- Sponsor
- Oregon Research Institute
Diabetes Mellitus, Non-Insulin-Dependent
Education and Group Support for Diabetic Hispanics
The purpose of this ongoing work in Starr County, located on the Texas-Mexico border, is to conduct clinical studies to determine the effectiveness of diabetes self-management programs designed specifically for Mexican Americans.
- Trial name
- NCT00004983
- Testing
- diabetes self-management education
- Where
- United States
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Non Insulin Dependent Diabetes
Effects of Curcumin Supplementation on Lipid Profile and Inflammatory Markers of Patients With Type 2 Diabetes
Diabetes mellitus is the most common endocrine disorder, causes many complications such as micro- and macro-vascular diseases. Various kinds of antidiabetic drugs have been developed, but most of them have side effects.
- Trial name
- NCT02529969
- Testing
- curcumin
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- National Nutrition and Food Technology Institute
Cardiovascular Diseases, Coronary Disease
Genetic Markers of Coronary Heart Disease in Type 2 Diabetes
To investigate genetic markers of coronary heart disease in type 2 diabetes.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Diabetes Mellitus, Non-insulin Dependent, Diabetes Mellitus
- Trial name
- NCT00078052
- Volunteers
- 120,000 people
- Sponsor
- Harvard School of Public Health (HSPH)
Diabetes Mellitus, Non-Insulin-Dependent
Clinical Trial With Broccoli Sprout Extract to Patients With Type 2 Diabetes
Type 2 diabetes (T2D) results from a combination of insufficient insulin secretion from pancreatic islets and insulin resistance of target cells.
- Trial name
- NCT02801448
- Testing
- sulforaphane
- Volunteers
- 103 people
- Sponsor
- Anders Rosengren, MD PhD