Clinical trials: Non-ST-Segment Elevation Myocardial Infarction (NSTEMI)
Myocardial Infarction, Acute
Korea Acute Myocardial Infarction Registry
This multicentre observational registry study, the Korea Acute Myocardial Infarction Registry (KAMIR-7), aims to improve long-term prognosis in Korean patients with acute myocardial infarction (AMI) by establishing and operating…
- Trial name
- KAMIR-7 (NCT07409441)
- Where
- 2 sites in South Korea
- Volunteers
- 20,000 people
- Sponsor
- Samsung Medical Center
Coronary Artery Disease, Coronary Syndrome
Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With (N)STEMI or Unstable Angina
The POLARSTAR study is an early safety and feasibility study to evaluate the performance and safety of the CryoTherapy System (CTS) for the treatment of coronary plaque lesions that are not obstructing blood flow but are at…
- Conditions
- Coronary Artery Disease, Coronary Syndrome, Cryotherapy Effect, Myocardial Infarction
- Trial name
- POLARSTAR (NCT05600088)
- Testing
- CryoTherapy System (CTS)
- Where
- 5 sites in Georgia, Lithuania
- Volunteers
- 24 people
- Sponsor
- Cryotherapeutics SA
Myocardial Infarction, STEMI
Breisgau PHENO-HEART MI
Coronary heart disease and its acute complication, myocardial infarction (MI), represent the leading causes of death in Europe and the United States.
- Conditions
- Myocardial Infarction, STEMI, NSTEMI
- Trial name
- NCT06166407
- Testing
- no intervention
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- University Hospital Freiburg
Coronary Artery Disease, Unstable Angina
Restore EF Observational Study
A multi-center, prospective, observational, non-interventional single arm, study of the intermediate-term clinical outcomes collected from electronic health records of high-risk patients which have previously undergone standard…
- Conditions
- Coronary Artery Disease, Unstable Angina, Angina, Stable, NSTEMI - Non-ST Segment Elevation MI
- Trial name
- NCT04648306
- Testing
- Prophylactic Impella support for a non-emergent PCI
- Where
- 21 sites in United States
- Volunteers
- 406 people
- Sponsor
- Abiomed Inc.
Coronary Artery Calcification, Ischemic Heart Disease
The Influence of Modifying Highly Calcified Coronary Lesions on Coronary Microcirculation
This is a prospective, single-center, three-arm study to evaluate the impact of severely calcified coronary lesions treatment on microvascular circulation.
- Conditions
- Coronary Artery Calcification, Ischemic Heart Disease, Non-ST-Segment Elevation Myocardial Infarction (NSTEMI), Coronary Artery Disease
- Trial name
- NCT06507449
- Testing
- Lithotripsy, Orbital atherectomy, High-pressure non-compliant balloon
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Silesia
Myocardial Infarction (MI), Heart Failure
Timing of Coronary Angiography in NSTEMI Complicated by Acute HF
Study objectives: To determine the optimal timing of coronary angiography (CAG) in patients with non-ST-segment elevation myocardial infarction (NSTEMI) complicated by acute decompensated heart failure (AHF).
- Trial name
- TIMING-AHF (NCT07002164)
- Testing
- Immediate coronary angiography, Delayed coronary angiography
- Where
- 20 sites in South Korea
- Volunteers
- 780 people
- Sponsor
- Chonnam National University Hospital
Multivessel Coronary Artery Disease, Vessel Disease
Functional Testing Underlying Coronary Revascularisation
The objective of this trial is to compare the clinical outcomes and cost-effectiveness of 2 therapeutic strategies, one based on coronary angiography guidance and the other based on coronary angiography with fractional flow…
- Conditions
- Multivessel Coronary Artery Disease, Vessel Disease, Stable Angina, Unstable Angina or Stabilized Non-ST Elevated Myocardial Infarction
- Trial name
- FUTURE (NCT01881555)
- Testing
- invasive coronary angiography, Functional testing by fractional flow reserve measurement
- Where
- France
- Volunteers
- 941 people
- Sponsor
- Hospices Civils de Lyon
Coronary Artery Disease
BIOFLOW III Satellite-ELADIS Orsiro Stent System
This registry is a clinical evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT02029092
- Where
- 14 sites in Spain
- Volunteers
- 404 people
- Sponsor
- C.E.M. Biotronik, S.A.
Coronary Artery Disease, Myocardial Infarction
Compressive Elastic Dressing Versus TR Band
Radial approach is widely established in cardiac diagnostic and therapeutic treatments. It has been shown to decrease bleeding, vascular problems, and mortality rates when compared to the femoral approach.
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Angina, Unstable, Angina, Stable
- Trial name
- Band Vs Gauze (NCT05409716)
- Testing
- Compressive Elastic dressing for hemostasis in cardiac procedure using radial approach, Wristband TR band for hemostasis in cardiac procedure using radial approach
- Where
- 2 sites in Palestinian Territories
- Volunteers
- 400 people
- Sponsor
- An-Najah National University
Non-ST Elevation Myocardial Infarction
Initial CT Perfusion-Guided Strategy for Suspected NSTEMI
Non-ST elevation myocardial infarction (NSTEMI) is a relatively complex type of myocardial infarction, characterized by chest pain symptoms and elevated troponin levels.
- Trial name
- SMART (NCT06689267)
- Testing
- computed tomography myocardial perfusion, Invasive Coronary Angiography
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Shanghai Zhongshan Hospital
ACS - Acute Coronary Syndrome, NSTEMI - Non-ST Segment Elevation MI
MCG Discovery Study in Emergency Departments
This prospective discovery study is designed to demonstrate the feasibility of using an unshielded, mobile MCG device in an Emergency Department (ED) setting.
- Trial name
- NCT06095557
- Testing
- Sponsor MCG device
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- SB Technology, Inc.
Cardiogenic Shock, Acute Myocardial Infarction
National Cardiogenic Shock Initiative
This study evaluates the use of early mechanical circulatory support in patients presenting with acute myocardial infarction and cardiogenic shock.
- Conditions
- Cardiogenic Shock, Acute Myocardial Infarction, STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation MI
- Trial name
- NCSI (NCT03677180)
- Where
- 75 sites in United States
- Volunteers
- 406 people
- Sponsor
- Henry Ford Health System
NSTEMI
Providing Rapid Out of Hospital Acute Cardiovascular Treatment (PROACT)
The purpose of this study is to determine if early diagnosis and risk stratification acquired through pre-hospital clinical assessment, 12-lead electrocardiogram and point of care biomarkers will facilitate enhanced triage and…
- Trial name
- PROACT (NCT01634425)
- Testing
- Alere Triage Meter Pro
- Where
- 5 sites in Canada
- Volunteers
- 601 people
- Sponsor
- University of Alberta
Coronary Artery Disease, Stable Angina
Validation of the MedHub AutocathFFR Software Device for Non-Invasive Fractional Flow Reserve (FFR)
This observational study evaluated how well the AutocathFFR software measures fractional flow reserve (FFR) from coronary angiogram images.
- Conditions
- Coronary Artery Disease, Stable Angina, Unstable Angina, Non-ST-Elevation Myocardial Infarction
- Trial name
- NCT07763769
- Testing
- MedHub AutocathFFR
- Where
- 4 sites in United States
- Volunteers
- 277 people
- Sponsor
- Medhub Ltd.
Non-ST-Segment Elevation Myocardial Infarction (NSTEMI)
EARLY-MYO-CMR-II Registry
The purpose of this registry is to depict the myocardial tissue characteristics in NSTEMI patients by CMR and other cardiac imaging modalities and to assess the prognostic value of imaging-derived indices.
- Trial name
- NCT03995433
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- RenJi Hospital
Non ST Elevation Myocardial Infarction (NSTEMI), Frailty
Frailty as an INstrument for Evaluation of Elderly Patients With Non ST Elevation Myocardial Infarction (NSTEMI)
The purpose of this study is to describe patients, 75 years old or older, with Non ST Elevation Myocardial Infarction (NSTEMI) especially regarding the following variables: cardiovascular risk, co-morbidity and frailty.
- Trial name
- FINE75+ (NCT01049997)
- Where
- Sweden
- Volunteers
- 307 people
- Sponsor
- Linkoeping University
Chronic Coronary Insufficiency, Non ST Elevation Myocardial Infarction
Pullback Pressure Gradient (PPG) Global Registry
The purpose of this study is to determine the predictive capacity of the Pullback Pressure Gradient (PPG) index for post-PCI FFR and to determine the impact of the PPG index on clinical decision making about revascularization and…
- Trial name
- PPG Global (NCT04789317)
- Where
- 23 sites in United States, Australia and 10 more
- Volunteers
- 982 people
- Sponsor
- VZW Cardiovascular Research Center Aalst
Non-ST-Elevation Myocardial Infarction
Thrombus Aspiration During Percutaneous Coronary Intervention in Acute Non-ST-elevation Myocardial Infarction Study
In this trial, the investigators will evaluate the effect of thrombus aspiration followed by stent implantation in improving myocardial blush grade in patients with acute non-ST-elevation myocardial infarction compared to…
- Trial name
- TAPAS II (NCT01013038)
- Testing
- Thrombus aspiration followed by stent implantation, conventional PCI
- Where
- Netherlands
- Volunteers
- 540 people
- Sponsor
- University Medical Center Groningen
Myocardial Infarction, Myocardial Ischemia
Vulnerable Plaque Imaging in NSTEMI
Myocardial infarction (MI) frequently recurs after non-ST elevation MI (NSTEMI) that may be related to insufficient vulnerable plaque identification using invasive coronary angiography.
- Trial name
- CULPRIT (NCT02563964)
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Maastricht University Medical Center
NonST Elevation Myocardial Infarction, Myocardial Infarction
Fractional Flow Reserve Versus Angiographically Guided Management to Optimise Outcomes in Unstable Coronary Syndromes
Background: In patients with acute non-ST elevation myocardial infarction (NSTEMI) coronary arteriography is usually recommended however visual interpretation of the coronary angiogram is subjective.
- Trial name
- FAMOUS NSTEMI (NCT01764334)
- Testing
- Fractional flow reserve
- Where
- 6 sites in United Kingdom
- Volunteers
- 350 people
- Sponsor
- NHS National Waiting Times Centre Board