Clinical trials: Non-Suicidal Self-Injury
Nonsuicidal Self-Injury
Effects of a School-Based Trauma-Informed Psychosocial Competence Intervention on Nonsuicidal Self-Injury in Adolescents
The purpose of this randomized controlled trial is to evaluate whether a school-based Trauma-Informed Psychosocial Competence (TIPC) intervention can reduce nonsuicidal self-injury among adolescents in China.
- Trial name
- TIPC-China (NCT07891754)
- Testing
- Trauma-Informed Psychosocial Competence (TIPC) Program
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Han Wu
Non-Suicidal Self Injury
A Case-Series Examination of a Brief CAT-Informed Intervention (CATCH-Y) for Young People That Have Self-Injured
Non-suicidal self-injury (NSSI), the term used for when somebody purposefully hurts themselves without intending to end their life. Often, it suggests that there are other difficulties going on in someone's life.
- Trial name
- CATCHY (NCT04708262)
- Testing
- Cognitive Analytic Therapy for Containing Self-Harm in Young People
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- University of Manchester
Psychological Distress, Suicidal Ideation
Flourish in Schools Pilot Study
This study will test Flourish, a digital suicide prevention intervention for cyberbullied youth, within schools. Specifically, the study aims to: 1.
- Trial name
- NCT07506525
- Testing
- Flourish
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Candice Biernesser
Problem Behavior, Aggression
Extensions of Resurgence as Choice
Although behavioral treatments for decreasing destructive behavior, such as differential reinforcement of alternative behavior (DRA), are effective in the clinic, problem behavior often returns when a caregiver does not give the…
- Conditions
- Problem Behavior, Aggression, Self-Injury
- Trial name
- NCT05537610
- Testing
- CDT, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Transcranial Magnetic Stimulation, Non-suicidal Self-injury
Stanford Neuromodulation Therapy (SNT) for Non-suicidal Self-injury (NSSI)
To investigate the treatment effect of Stanford Neuromodulation Therapy (SNT) on patients with Non-suicidal Self-injury (NSSI) and the underlying neural mechanism.
- Trial name
- NCT06139484
- Testing
- Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Non Suicidal Self Injury
The Effect of Intravenous Ketamine on Non Suicidal Self Injuries.
Non-suicidal self-injuries (NSSI) is a deliberate harm a person causes directly to their body, resulting in structural or functional damage, without suicidal ideation.
- Trial name
- NCT04242914
- Testing
- Ketamine, Midazolam
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Psychological Distress, Suicidal Ideation
MBI for Psychological Distress, SI and NSSI Among Young Adults
Designed to measure the impact of Mindfulness Based Intervention on depression, anxiety, stress, psychological distress, Suicidal Ideation, Non-Suicidal Self Injury urge and Mindfulness in young adults.
- Conditions
- Psychological Distress, Suicidal Ideation, Non-Suicidal Self Injury
- Trial name
- NCT06263335
- Testing
- Mindfulness Based Stress Reduction Intervention
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatima Jinnah Women University
Nonsuicidal Self-injury
Internet Delivered ERITA for Nonsuicidal Self-Injury
To evaluate if Internet delivered emotion regulation individual therapy for adolescents is an efficacious treatment when delivered as adjunctive to treatment as usual compared to a control group consisting of treatment as usual.
- Trial name
- ERITA (NCT03353961)
- Testing
- Emotion regulation individual therapy, Treatment as usual
- Where
- 2 sites in Sweden
- Volunteers
- 166 people
- Sponsor
- Karolinska Institutet
Suicidal Ideation
Observational Study to Compare Outcomes of Different Psychiatric Treatment of Suicidal Adolescents
To address the unmet need of optimizing the treatment and management for adolescent suicidality, the investigators propose to evaluate the effectiveness and safety of telehealth services compared to inpatient and OCIC for…
- Trial name
- Pre-START (NCT04625686)
- Testing
- Mental Health Treatment
- Where
- 4 sites in United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Nonsuicidal Self Injury, Alcohol Abuse
Technology Enhanced Adolescent Mental Health (TEAM)
Adolescent nonsuicidal self-injury (NSSI) and alcohol misuse, alone and especially in combination, portend significant functional impairment in adulthood (e.g., relationship dysfunction, depression, suicidality).
- Conditions
- Nonsuicidal Self Injury, Alcohol Abuse, Vagus Nerve Stimulation
- Trial name
- TEAM (NCT05343039)
- Testing
- Non-invasive Transcutaneous Nerve Stimulation (tVNS), No Intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Suicidal Ideation Active, Depression Disorders
Personalized TACS to Reduce Rumination in Patients with Active Suicidal Ideation
The goal of this clinical trial is to determine whether modulating default mode network (DMN) alpha connectivity using transcranial alternating current stimulation (tACS) can reduce rumination and, in turn, mitigate feelings of…
- Trial name
- Alpha-MOD (NCT06832124)
- Testing
- alpha-tACS
- Volunteers
- 50 people
- Sponsor
- Sebastian Olbrich
Self-Harm, Deliberate, Suicide, Attempted
Brief Admission for Adolescents Who Self-harm
There is still no consensus on how to manage suicidal behavior in youth with recurrent self-harm at times when the risk for suicide is imminent (1).
- Conditions
- Self-Harm, Deliberate, Suicide, Attempted, Suicidal, Non-Suicidal Self Injury
- Trial name
- NCT04962373
- Testing
- Semi-structured interviews
- Where
- Sweden
- Volunteers
- 59 people
- Sponsor
- Region Skane
Non-suicidal Self-injury (NSSI)
Acceptance and Commitment Therapy-Based Chatbot for Non-suicidal Self-Injury in Adolescents
The purpose of this study is to evaluate the feasibility and effectiveness of a self-guided digital Acceptance and Commitment Therapy (ACT) intervention for adolescents who engage in non-suicidal self-injury (NSSI).
- Trial name
- NCT07848620
- Testing
- ACT-Based Chatbot
- Volunteers
- 100 people
- Sponsor
- Central China Normal University
Self-Injurious Behavior
CALMA App as an Adjunct to Therapy for Reduction of Suicidal and Non-Suicidal Self-Injurious Behaviors in Adolescents
Suicide in the second cause of death in subjects between 15 and 24 years of age. Despite the efficacy of interventions for the management of suicidal crises observed in some clinical trials, a crucial aspect for their…
- Trial name
- NCT05453370
- Testing
- CALMA m-health app, Treatment As Usual (TAU)
- Where
- 4 sites in Argentina
- Volunteers
- 58 people
- Sponsor
- University of Buenos Aires
Autism Spectrum Disorder, Challenging Behaviour
Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism
The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression, self-injury, and severe disruptive behaviors.
- Conditions
- Autism Spectrum Disorder, Challenging Behaviour, Aggression, Severe Disruptive Behaviour Disorders
- Trial name
- NCT07091279
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Jeremy Veenstra-vanderweele
Depression, Self-injurious Behavior
Interpersonal Psychotherapy for Depressed Adolescents Engaging in Non-suicidal Self-injury
The purpose of this study is to examine the feasibility of using Interpersonal Psychotherapy for Depressed Adolescents (IPT-A) to treat adolescents who are experiencing symptoms of depression and are engaging in non-suicidal…
- Trial name
- IPT-ASI (NCT00401102)
- Testing
- Interpersonal Psychotherapy for Depressed Adolescents
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New York State Psychiatric Institute
Non-suicidal Self-injury
Research on the Intervention of VR-based Emotion Regulation Technology on Adolescent Non-suicide Self-injury Behavior
Non suicidal self injury (NSSI) has become a serious social and public health problem allover the world, and the incidence rate is increasing year by year.
- Trial name
- VR (NCT05734872)
- Testing
- Virtual Reality Technology, Routine mental health course training
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Nonsuicidal Self Injury, Nonsuicidal Self-Injury
Psychological Treatment for Adolescents With Self-injury Within Intensive Mental Health Outpatient Services: Randomized Controlled Pilot Trial
The overarching aim of this study is to develop and evaluate a new blended treatment format, which combines face-to-face and digital treatment components, for Emotion Regulation Individual Therapy for Adolescents (ERITA).
- Conditions
- Nonsuicidal Self Injury, Nonsuicidal Self-Injury, Self-Harm
- Trial name
- NCT07755774
- Testing
- Blended ERITA, Treatment as Usual (TAU), Concomitant care
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Adolescent - Emotional Problem, Adolescent Problem Behavior
Treating Self-criticism in Adolescents: a Study With Single-case Experimental Design
In this pilot study, the effect of a group intervention targeting self-criticism in adolescents in a clinical child- and adolescent psychiatric outpatient setting will be examined using a single-case experimental design (AB).
- Conditions
- Adolescent - Emotional Problem, Adolescent Problem Behavior, Nonsuicidal Self Injury, Depressive Symptoms
- Trial name
- NCT05247190
- Testing
- Treating self-criticism
- Where
- Sweden
- Volunteers
- 19 people
- Sponsor
- Region Östergötland
Non-suicidal Self-injury
Effects of taVNS Combined With tACS on Adolescents With Non-Suicidal Self-Injury
NSSI behavior is highly prevalent among adolescents, and its mechanisms are closely associated with attentional bias toward self-injury-related information and impulsivity, both of which may be related to reduced dlPFC activation…
- Trial name
- NCT07486804
- Testing
- 25Hz、300us transcutaneous auricular vagus nerve stimulation and10hz transcranial alternating current stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University