Clinical trials: Non-Suicidal Self-Injury
Nonsuicidal Self-Injury, Anxiety
Acceptance and Commitment Therapy for Nonsuicidal Self-injury
The goal of this study is to evaluate the effectiveness of Acceptance and Commitment Therapy (ACT) for individuals who engage in nonsuicidal self-injury(NSSI) and have comorbid anxiety.
- Trial name
- NCT03548402
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Southern Methodist University
Non-Suicidal Self-Injury, Emotional Dysregulation
Integrated Motivational Interviewing and Rational Emotive Behavior Therapy Intervention for Non-Suicidal Self-Injury Among Malaysian Primary School Students: A Feasibility Trial Protocol
This study aims to evaluate the feasibility and preliminary effects of the MIND-SET Intervention Module, an integrated Motivational Interviewing and Rational Emotive Behavior Therapy (MI-REBT) intervention, among Malaysian…
- Trial name
- MIND-SET (NCT07627061)
- Testing
- MIND-SET Intervention Module, PRISMA Mental Health Module
- Where
- Malaysia
- Volunteers
- 105 people
- Sponsor
- Universiti Utara Malaysia
Self-harm Behavior, Eating Disorders
Evaluation of National Highly Specialized Care for Adults With Treatment-Resistant Self-Harm and Eating Disorders: Substudy 1
This study aims to evaluate National Highly Specialized Care (NHV) for adults with severe and treatment-resistant self-harm or eating disorders in Sweden.
- Conditions
- Self-harm Behavior, Eating Disorders, Non-suicidal Self-injury (NSSI)
- Trial name
- NHV_ADULTS (NCT07878897)
- Testing
- National Highly Specialized Care (NHV)
- Where
- 2 sites in Sweden
- Volunteers
- 250 people
- Sponsor
- Karolinska Institutet
Self Injurious Behavior, Self Injurious Behavior Without Suicidal Intent
Examining the Effectiveness of a Brief Therapeutic Intervention for Reducing Self-Harm Among Adolescents
Non-suicidal self-injury (NSSI), defined as deliberate self-inflicted destruction of body tissue without intent to die, is particularly prevalent during mid-adolescence, with prevalence estimated around 16-22% in community…
- Trial name
- NCT07913425
- Testing
- Cutting Down Program - a three-month cognitive-behavioral psychotherapy focused on reducing self-injury urges and behaviors in adolescents
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- University of Haifa
Borderline Personality Disorder
DBT for Chronically Self-harming Individuals With BPD: Evaluating the Clinical & Cost Effectiveness of a 6 mo. Treatment
Standard one-year dialectical behaviour therapy (DBT), which has four components, is an effective treatment for people with borderline personality disorder.
- Trial name
- FASTER-DBT (NCT02387736)
- Testing
- Dialectical Behaviour Therapy-6 months, Dialectical Behaviour Therapy-12 months
- Where
- 2 sites in Canada
- Volunteers
- 240 people
- Sponsor
- Centre for Addiction and Mental Health
Nonsuicidal Self-Injury, Self-Injurious Behavior
Naltrexone for Nonsuicidal Self-Injury
This randomized, double-blinded, placebo-controlled clinical trial aims to evaluate the efficacy and safety of naltrexone in reducing nonsuicidal self-injurious behavior among individuals with nonsuicidal self-injury.
- Trial name
- NCT07641283
- Testing
- Naltrexone 50mg (Whanin Naltrexone Tab. 50mg)
- Where
- 3 sites in South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Major Depressive Episode (MDE), Major Depressive Disorder (MDD)
LHC-CIDI-5 in Hong Kong
The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12…
- Conditions
- Major Depressive Episode (MDE), Major Depressive Disorder (MDD), Persistent Depressive Disorder (PDD), Suicidal Ideation
- Trial name
- NCT06804525
- Testing
- CIDI-5, LHC-CIDI-5
- Where
- Hong Kong
- Volunteers
- 2,500 people
- Sponsor
- The University of Hong Kong
Non Suicidal Self Injury
The Development of Psychiatric Non-Suicidal Self-Injury Risk Assessment Scale
Non-suicidal self-injury (NSSI) is a growing global mental health challenge, distinct from suicidal behavior, with unique risk factors and mechanisms.
- Trial name
- NCT06603389
- Testing
- Psychiatric Non-Suicidal Self-Injury Risk Assessment Scale
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Shantou University Medical College
Aggressive Behavior in Fragile X Syndome
Inhibition of Aggressive Behavior in Participants With Fragile X Syndrome
The goal of this clinical trial is to learn if drug SRX246 works to treat irritability, agitation, aggression and self-injury (IAAS) behaviors in adult males with Fragile X Syndrome (FXS).
- Trial name
- NCT07328529
- Testing
- SRX246
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Azevan Pharmaceuticals
Non-suicidal Self-injury
Treatment for Non-Suicidal Self-Injury in Young Adults
The purpose of this study is to investigate an intervention specifically for non-suicidal self-injury (NSSI) in young adults. The goal of this 9-session outpatient intervention is to reduce the frequency and severity of NSSI.
- Trial name
- T-SIB (NCT01018433)
- Testing
- T-SIB, Treatment as usual
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fordham University
Self-Injurious Behavior
Zero Self-Harm - a Mobile Phone Application to Reduce Non-suicidal Self-injury
Non-suicidal self-injury (NSSI), the deliberate, self-inflicted destruction of body tissue without suicidal intent and for purposes not socially sanctioned, is an increasing health care problem in Denmark.
- Trial name
- NCT04463654
- Testing
- Zero Self-Harm app
- Where
- Denmark
- Volunteers
- 280 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Suicidal Ideation, Depression
Gamified VR Sports for Elderly Suicidal Ideation
Detailed Description: This quasi-experimental study investigates the effectiveness of a gamified sports exercise intervention delivered through virtual reality (VR) to improve mental health and life expectancy in elderly…
- Conditions
- Suicidal Ideation, Depression, Mental Health Issue
- Trial name
- VR-LIFE-SI (NCT06856083)
- Testing
- Gamified Virtual Reality Sports Exercise Program, Traditional Sports Exercise Program for Elderly Individuals with Suicidal Thoughts
- Where
- Iran
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Nonsuicidal Self Injury, Emotion Regulation
Emotion Regulation Dysfunctions in NSSI Adolescents in Naturalistic Contexts
Nonsuicidal self-injury (NSSI) is defined as direct, deliberate bodily harm without suicidal intention. Recent studies indicate that prevalence rates are increasing worldwide, in particular under adolescents, indicating a growing…
- Trial name
- NCT05907421
- Testing
- Acceptance mindset
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Depression in Adolescence, Suicidal Ideation
Stratified Care Intervention for Suicidal Ideation, Depression, and Non-Suicidal Self-Injury in Adolescents (Reframe-IT+ & CARIBOU)
The aim of this study is to evaluate the acceptability, feasibility, and fidelity of implementing a stratified care intervention for adolescents with suicidal ideation and depressive symptoms, and to preliminarily explore its…
- Conditions
- Depression in Adolescence, Suicidal Ideation, Non Suicidal Self Injury
- Trial name
- NCT07780084
- Testing
- Reframe-IT and CARIBOU
- Where
- Chile
- Volunteers
- 90 people
- Sponsor
- Universidad de los Andes, Chile
Nonsuicidal Self-Injury
Emotion Regulation Individual Therapy for Adolescents With NSSI - An Open Pilot Study
The primary aim is to investigate the effectiveness of Emotion Regulation Individual Therapy for Adolescents (ERITA) who self-harm.
- Trial name
- NCT02326012
- Testing
- Emotion Regulation Individual Therapy for Adolescents
- Where
- Sweden
- Volunteers
- 17 people
- Sponsor
- Karolinska Institutet
Self-harm, Personality Disorder, Borderline
Self-harm Behaviour Among the Most At-risk Adolescents
In the proposed study, three objectives will be pursued: 1. To develop a method to identify more effectively the acute and long-term risk of adolescents with the most threatening self-harm behaviours. 2.
- Conditions
- Self-harm, Personality Disorder, Borderline, Epigenetic Disorder, Non-Suicidal Self Injury
- Trial name
- SH-MARA (NCT05765864)
- Testing
- Enrollment questionnaire, General questionnaire1, General questionnaire2, General questionnaire3, Columbia Suicide Severity Rating Scale (CSSRS), The Brief Non-Suicidal Self-Injury Assessment Tool (B-NSSI-AT)
- Where
- 2 sites in Slovenia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana, Faculty of Medicine
Autism Spectrum Disorder, Regulation, Self
Development of Self-regulation by Dialectial Behavioural Therapy in Adults With Autism
Individuals with autism spectrum disorder (ASD) are at risk to develop more pervasive emotion-dysregulation. In this study experiences of adults with ASD and severe emotion dysregulation with Integrative Dialectical Behaviour…
- Trial name
- DASHBOARD (NCT05502484)
- Testing
- Integrative Dialectical Behavioural Therapy (DBT)
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Nonsuicidal Self-injury, ADHD
Formal Versus Informal Mindfulness Among University Students With Self-reported ADHD, Nonsuicidal Self-injury, or Stress
The present study will use a randomized controlled design to investigate group differences between university students with self-reported stress (comparison group), ADHD, or a history of nonsuicidal self-injury (NSSI) in response…
- Conditions
- Nonsuicidal Self-injury, ADHD, Mindfulness
- Trial name
- NCT06038942
- Testing
- Formal mindfulness instruction, Informal mindfulness instruction
- Where
- 2 sites in Canada
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- McGill University
Borderline Personality Disorder, Non-suicidal Self-injury (NSSI)
ERGT for Women Engaging in NSSI - an Effectiveness Study
The primary aim is to investigate the effectiveness of Emotion Regulation Group Therapy (ERGT) for women who self-harm in ordinary psychiatric outpatient health care.
- Trial name
- NCT01986257
- Testing
- Emotion Regulation Group Therapy (ERGT).
- Where
- Sweden
- Volunteers
- 97 people
- Sponsor
- Karolinska Institutet
Adolescent Mental Health, Psychosocial Adaptation
Trauma-Informed School Intervention for Adolescent Mental Health and Self-Injury Prevention in China
This study evaluated a school-based psychosocial adaptive capacity enhancement program for Chinese adolescents. The program was developed to support students who may have experienced childhood household dysfunction or other…
- Conditions
- Adolescent Mental Health, Psychosocial Adaptation, Childhood Household Dysfunction
- Trial name
- TISI-China (NCT07583524)
- Testing
- School-Based Psychosocial Adaptive Capacity Enhancement Program
- Where
- China
- Volunteers
- 5,787 people, healthy volunteers welcome
- Sponsor
- WU Han