Clinical trials: Non-celiac Wheat Sensitivity
Not-celiac Gluten (Wheat) Sensitivity
Bioelectrical Impedance Analysis of Not-celiac Wheat Sensitivity Patients
Aim of the investigators' study is to evaluate one of the symptoms described by patients affected with the so-called "not-celiac wheat sensitivity" (NCWS).
- Trial name
- NCT01762566
- Testing
- wheat, xylose
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- University of Palermo
Non-celiac Wheat Sensitivity
Response to Different Wheat Genotypes in Not-celiac Wheat Sensitivity
Non-celiac gluten sensitivity (NCGS) is a condition where intestinal and extraintestinal symptoms are triggered by gluten ingestion in the absence of celiac disease and wheat allergy.
- Trial name
- NCT03024775
- Testing
- Wheat flour
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Palermo
Non Celiac Wheat Sensitivity
Nickel Allergy and Systemic Nickel Allergy Syndrome in Non Celiac Wheat Sensitivity
In the last few years, a new clinical entity has emerged which includes patients who consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have celiac disease (CD) or…
- Trial name
- NCT02750735
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- University of Palermo
Non-celiac Wheat Sensitivity
KIR Genes and Non-Celiac Wheat Sensitivity
Non-celiac gluten sensitivity (NCGS) is a condition characterized by gastrointestinal and extraintestinal symptoms which are triggered by gluten ingestion in the absence of celiac disease (CD) and wheat allergy.
- Trial name
- NCT05469971
- Testing
- KIR genotyping
- Where
- 4 sites in Italy
- Volunteers
- 170 people
- Sponsor
- University of Palermo
Non-celiac Wheat Sensitivity
Oral Lesions In Non-Celiac Wheat Sensitivity Patients
Non-celiac gluten sensitivity (NCGS) or 'wheat sensitivity' (NCWS) is included in the spectrum of gluten-related disorders. No data are available on the prevalence of oral lesions in NCWS.
- Trial name
- NCT02421809
- Where
- 2 sites in Italy
- Volunteers
- 270 people
- Sponsor
- University of Palermo
Not-celiac Gluten Sensitivity
Diagnostic Significance of Positive EmA Antibodies in the Duodenal Culture Medium of Not-Celiac Wheat Sensitivity (NCWS)
The most frequent diseases caused by wheat ingestion are T cell-mediated disorders, i.e. celiac disease and immunoglobulin E (IgE)-mediated allergic reactions.
- Trial name
- NCWS (NCT02203201)
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Palermo
Non-celiac Gluten Sensitivity, Non-celiac Wheat Sensitivity
Autoimmune Diseases and Serum Autoantibodies in NCWS and IBS Patients
In recent years, a new gluten- or wheat-related disease has emerged, a condition labelled "non-celiac gluten sensitivity" (NCGS) or "non-celiac wheat sensitivity" (NCWS).
- Trial name
- NCT04077840
- Where
- 2 sites in Italy
- Volunteers
- 58 people
- Sponsor
- University of Palermo
Non Celiac Wheat Sensitivity, IBS (Irritable Bowel Syndrome)
NCWS or IBS/FD in Relatives of CD Patients
Over 50% of non-celiac wheat sensitivity (NCWS) patients are HLA DQ2/DQ8 positive and often have a Celiac Disease (CD) family history.
- Conditions
- Non Celiac Wheat Sensitivity, IBS (Irritable Bowel Syndrome), Functional Dyspepsia, Celiac Disease
- Trial name
- NCT07584473
- Testing
- Wheat-Free Diet
- Where
- 2 sites in Italy
- Volunteers
- 600 people
- Sponsor
- University of Palermo
Metabolic Dysfunction-Associated Steatotic Liver Disease, Non Celiac Wheat Sensitivity
Liver Steatosis and Fibrosis in Non-Celiac Wheat Sensitivity Patients: a Prospective Study
Hypothesizing an intestinal barrier impairment as a common pathophysiological substrate of both Non Celiac Wheat Sensitivity (NCWS) and Metabolic Dysfunction-Associated Steatotic Liver Disease (MAFLD), in a retrospective cohort…
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Non Celiac Wheat Sensitivity, Irritable Bowel Syndrome, Functional Dyspepsia
- Trial name
- NCT07750535
- Testing
- Prevalence and severity of liver steatosis and fibrosis,
- Where
- 2 sites in Italy
- Volunteers
- 250 people
- Sponsor
- University of Palermo
Non-celiac Wheat Sensitivity
Fibromyalgia-like Joint/Muscle Pain and Synovitis in Non-celiac Wheat Sensitivity Patients
Recently it has been reported that a consistent percentage of the general population consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have CD or wheat allergy.
- Trial name
- NCT03022513
- Testing
- Gluten free diet
- Where
- 2 sites in Italy
- Volunteers
- 150 people
- Sponsor
- University of Palermo
Not-celiac Wheat Sensitivity
Bio-markers of Not-celiac Wheat Sensitivity
The aim of the investigators' study is to evaluate biochemical, immunological and histological characteristics of patients affected with the so-called "gluten (or wheat) sensitivity" who suffers from irritable bowel syndrome…
- Trial name
- NCT01762579
- Testing
- wheat flour, Xylose
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University of Palermo
Non-celiac Wheat Sensitivity
Abdominal Ultrasound Examination in Non-celiac Wheat Sensitivity
Recently it has been reported that a consistent percentage of the general population consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have CD or wheat allergy.
- Trial name
- NCT03017274
- Testing
- Abdominal ultrasound examination
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University of Palermo
Non-Celiac Wheat Sensitivity
Malnutrition In Non-Celiac Wheat Sensitivity Patients
Non-celiac gluten sensitivity (NCGS) or 'wheat sensitivity' (NCWS) is included in the spectrum of gluten-related disorders. No data are available on the prevalence of low bone mass density (BMD) in NCWS.
- Trial name
- NCT02421796
- Where
- 2 sites in Italy
- Volunteers
- 270 people
- Sponsor
- University of Palermo
Non-celiac Gluten Sensitivity
Extraintestinal Non Celiac Wheat Sensitivity
Non Celiac Gluten Sensitivity (NCGS), or, better, Non Celiac Wheat Sensitivity (NCWS), since it is not known the real pathogenetic component(s) of grain, is a syndrome characterized by a cohort of symptoms, both gastrointestinal…
- Trial name
- NCT04769180
- Testing
- Evaluation of extraintestinal manifestations
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- University of Palermo
Non-celiac Wheat Sensitivity
Gynaecological Disorders in Not-celiac Wheat Sensitivity
In the last few years, a new clinical entity has emerged which includes patients who consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have celiac disease (CD) or…
- Trial name
- NCT03027492
- Testing
- Gluten free diet, NCWS open challenge with wheat
- Where
- 3 sites in Italy
- Volunteers
- 500 people
- Sponsor
- University of Palermo
Gluten Sensitivity, Wheat Sensitivity
Effects of a Probiotic Supplementation on Symptoms and Microbiome Characteristics in Patients With Non-celiac Gluten/Wheat Sensitivity.
The aim of this randomized, double-blind, placebo-controlled clinical trial is to investigate the effects of probiotics on symptoms and gut microbiota composition following gluten reintroduction.
- Trial name
- NCT06884241
- Testing
- Probiotic supplementation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Turin, Italy
Non-celiac Gluten Sensitivity, Wheat Intolerance
Bread Study: Comparison of the Tolerance of Spelt and Wheat Bread
This project aims to verify the hypothesis that spelt products are more tolerable than bread wheat products in a target group of individuals with self-diagnosed wheat sensitivity.
- Trial name
- NCT04401956
- Testing
- bread
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Non-celiac Wheat Sensitivity
Self-reported Gluten Sensitivity in High-school Students
It has been reported that a consistent percentage of the general population consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have celiac disease or wheat allergy.
- Trial name
- NCT03021148
- Testing
- Questionnaire
- Where
- 2 sites in Italy
- Volunteers
- 500 people
- Sponsor
- University of Palermo
Not-celiac Wheat Sensitivity (NCWS), Familial Mediterranean Fever (FMF)
Gluten-related Disorders in Familial Mediterranean Fever Patients
It is known that the gluten-containing grains can be responsible for human diseases related to gluten exposure. These forms of gluten intolerance represent a heterogeneous set of conditions, including celiac disease (CD), wheat…
- Trial name
- NCT03563300
- Testing
- Wheat flour
- Where
- 2 sites in Italy
- Volunteers
- 8 people
- Sponsor
- University of Palermo
Non-celiac Wheat Sensitivity
Duodenal and Rectal Histology in Non-celiac Wheat Sensitivity and Irritable Bowel Syndrome Patients
Recently it has been reported that a consistent percentage of the general population consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have CD or wheat allergy.
- Trial name
- NCT03022994
- Testing
- Duodenum and rectum examination
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- University of Palermo