Clinical trials: Non-communicable Diseases (NCD)
Noncommunicable Diseases, Hypertension
Integrated NCD Intervention in Rural Nepal
We will test an NCD intervention bundle incorporating the World Health Organisation (WHO)'s Package for Essential Non-Communicable Disease Interventions (PEN) within an approximate population of 300,000 people in rural Nepal.
- Conditions
- Noncommunicable Diseases, Hypertension, Chronic Obstructive Pulmonary Disease, Diabetes Mellitus, Type 2
- Trial name
- NCT04087369
- Testing
- Bundled NCD WHO PEN Intervention
- Where
- 2 sites in Nepal
- Sponsor
- Possible
HIV/AIDS, Noncommunicable Diseases
Harambee: Integrated Community-based HIV/NCD Care & Microfinance Groups in Kenya
The objective of this project is to demonstrate the effectiveness and longer-term sustainability of a differentiated care delivery model for improving HIV treatment outcomes.
- Conditions
- HIV/AIDS, Noncommunicable Diseases, Hypertension, Diabetes
- Trial name
- NCT04417127
- Testing
- Integrated Community-Based (ICB) Care, Group-level Microfinance
- Where
- Kenya
- Volunteers
- 1,200 people
- Sponsor
- Brown University
Mental Health Disorder, Non Communicable Diseases
BECOME COmbined Intervention for MH & NCD Delivered by Community Health Workers in Nepal
Common mental health disorders (CMDs) and noncommunicable diseases (NCDs) pose significant public health challenges, especially in resource-limited settings like Nepal.
- Trial name
- BECOME (NCT06449521)
- Testing
- BECOME intervention
- Where
- Nepal
- Volunteers
- 700 people
- Sponsor
- Possible
Hypertension, Diabetes
Using Healthcare Financing and Digital Technology to Improve Hypertension Prevention and Control in Tanzania
The aim of our proposed program is to develop and implement a multilevel, multicomponent and health-financing intervention that will facilitate the scale up of evidence-based strategies to improve non-communicable diseases…
- Trial name
- NCT06379750
- Testing
- Nurse-delivered care using WelTel check-ins and BCC SMS, Community-based peer-support model
- Volunteers
- 1,320 people
- Sponsor
- Dr. Karen Yeates
Non-communicable Diseases (NCD), Addiction to Opioids
Systematic Examination of Health Inequalities: Documentation, Patterns, and Determinants
The existence of social inequalities is a major global issue and a salient challenge for the European Union. During COVID-19 pandemic, health disparities became more evident.
- Conditions
- Non-communicable Diseases (NCD), Addiction to Opioids, Incarceration, Opioid-use Disorders
- Trial name
- CHANCE (NCT07558187)
- Where
- 5 sites in Greece
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Diabete Mellitus, Cardiovascular Disease Risk Factor
The Mauritius and Rodrigues Non-Communicable Disease (NCD) Study
Mauritius is located in the southern Indian Ocean with a population of 1.3 million in 2023. Mauritius is a multiethnic nation with 68% South Asian, 27% African (Creole), 3% Chinese and 2% Franco Mauritians.
- Conditions
- Diabete Mellitus, Cardiovascular Disease Risk Factor, Ischemic Cardiovascular Disease, Hypertension
- Trial name
- NCT07048717
- Where
- Mauritius
- Volunteers
- 39,082 people, healthy volunteers welcome
- Sponsor
- Umeå University
Non-communicable Diseases (NCD), Neoplams
Health for Hungary (H4H) - Longitudinal Collection of Blood Samples and Corresponding Data
The Health for Hungary (H4H) study collects blood samples and corresponding health data to investigate healthy aging and health-to-disease transitions in middle-aged and elderly participants.
- Conditions
- Non-communicable Diseases (NCD), Neoplams, Cancer, Lung Cancer (NSCLC)
- Trial name
- H4H (NCT07743021)
- Where
- 33 sites in Hungary
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Center for Molecular Fingerprinting Research Nonprofit LLC
Cardiovascular Disease, Diabetes Type II
Evaluation of Novartis Access; a Non-communicable Disease (NCD) Access Initiative
Countries throughout the world are facing a growing non-communicable disease (NCD) burden. In developing countries, medicines to treat NCDs are often difficult to access or too expensive for many households.
- Conditions
- Cardiovascular Disease, Diabetes Type II, Breast Cancer, Asthma
- Trial name
- NCT02773095
- Testing
- Novartis Access
- Volunteers
- 966 people
- Sponsor
- Boston University
Diabetes Mellitus, Type 2, Hypertension
Scaling Up NCD Interventions in South East Asia
The SUNI-SEA study is an intervention study that measures effectiveness and cost-effectiveness of prevention and early diagnosis of diabetes and cardiovascular diseases in communities and primary healthcare (PHC) facilities in…
- Conditions
- Diabetes Mellitus, Type 2, Hypertension, Cardiovascular Diseases
- Trial name
- SUNI-SEA (NCT05239572)
- Testing
- screening, prevention and counselling
- Where
- Vietnam
- Volunteers
- 16,850 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Obesity
Development of a Group Prenatal Care Intervention to Address Maternal and Child Non-Communicable Disease (NCD) Risk in American Samoa
To test the efficacy of a group prenatal care intervention to reduce the risk of obesity related health conditions during and after pregnancy in obese mothers and their infants.
- Trial name
- NCT04025268
- Testing
- Group Prenatal Care (GPNC), Standard of Care
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yale University
Noncommunicable Diseases, Health Knowledge, Attitudes, Practice
School-based e-Health Non-Communicable Disease (NCD) Prevention Program
The goal of this sequential mixed method study is to assess the feasibility and effectiveness of a school-based eHealth-NCD prevention program intervention to improve adolescents' knowledge, attitude, and practices regarding NCDs…
- Conditions
- Noncommunicable Diseases, Health Knowledge, Attitudes, Practice, Non-communicable Disease Risk Factors
- Trial name
- NCT06674798
- Testing
- School-based eHealth NCD Prevention Program
- Where
- 7 sites in Pakistan
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Lifestyle Intervention, Non Communicable Diseases
Internet Technology Based Life-style and Care Intervention for Risk Factors of Non Communicable Diseases（NCD）
This study aims to control risk factors of non communicable diseases by life style and care intervention based on internet technology, looking forward to improve cardiovascular and cerebrovascular complications, diabetes and…
- Trial name
- NCT04567121
- Testing
- Intensive intervention group, standard intervention group
- Where
- China
- Volunteers
- 60,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Non-communicable Disease Risk Factors
Reducing Behavioral Risk Factors of NCDs: Protocol for a School-based Health Education Program in Bangladesh
This is a before-after designed intervention study conducted in two randomly selected secondary schools- one was selected randomly as intervention school and the another as control school.
- Trial name
- NCT03975335
- Testing
- Health education, Carrier Guidance
- Where
- Bangladesh
- Volunteers
- 823 people, healthy volunteers welcome
- Sponsor
- Chi Research & Infotec Ltd.
Exposome, Non-communicable Diseases (NCD)
Analysis of the Influence of the Exposome in Patients With Non-communicable Diseases
It is well documented that factors such as obesity, a sedentary lifestyle, and comorbidities-including hypertension, diabetes, and dyslipidemia-increase the risk of developing non-communicable diseases (NCDs).
- Conditions
- Exposome, Non-communicable Diseases (NCD), Non-communicable Disease Risk Factors
- Trial name
- EXPOSOME (NCT07879378)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 2,500 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Type 2 Diabetes (T2DM)
Implementing WHO HEARTS-D Guidelines in Bangladesh for Diabetes Control and Prevention
Type-2 diabetes (T2D) is rising at an alarming rate in the low- and middle-income countries (LMIC). This rapid increase in the T2D burden has a particular impact on cities, where more than half the LMIC populations currently live…
- Trial name
- T2D IR (NCT07155902)
- Testing
- The community-to-facility integrated strategy
- Volunteers
- 5,000 people
- Sponsor
- Florida International University
HIV (Human Immunodeficiency Virus), AIDS (Acquired Immune Deficiency Syndrome)
Antiretroviral Therapy and Inflammatory and Coagulation Biomarkers: iMACS Study
The aim of this study is to develop and follow a cohort of human immunodeficiency virus (HIV)-infected adults who are starting HIV drugs at health facilities in Kenya.
- Conditions
- HIV (Human Immunodeficiency Virus), AIDS (Acquired Immune Deficiency Syndrome), Tuberculosis, Non-communicable Diseases (NCD)
- Trial name
- iMACS (NCT02027480)
- Where
- 9 sites in Kenya
- Volunteers
- 685 people
- Sponsor
- Columbia University
Non-Communicable Chronic Diseases
Prevalence of NCD Risk Factors in Kazakhstan
This is a cross-sectional study that aims to study the prevalence of risk factors of noncommunicable diseases in people aged 18 to 69 years using the standardized and adopted STEPS questionnaire in the Republic of Kazakhstan.
- Trial name
- NCT05122832
- Testing
- Blood test, STEPwise Approach to NCD Risk Factor Surveillance (STEPS), Spirometry
- Where
- Kazakhstan
- Volunteers
- 20,400 people
- Sponsor
- Asfendiyarov Kazakh National Medical University
Non-communicable Diseases (NCD)
Enabling Environments for Non-communicable Disease Risk Reduction in Ethiopia
The ENABLE study focuses on pregnant women attending routine antenatal care (ANC) in urban primary health care facilities in four Ethiopian cities.
- Trial name
- ENABLE (NCT07442318)
- Testing
- Structured lifestyle counseling integrated into ANC, Standard routine ANC
- Where
- 4 sites in Ethiopia
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Tobacco Cessation, Health Warning Label
Health Warnings and Counseling for Smoking Cessation
Tobacco use remains persistently high across South Asia, despite numerous public health efforts, and continues to significantly contribute to the burden of non-communicable diseases (NCDs) such as cardiovascular disease…
- Conditions
- Tobacco Cessation, Health Warning Label, Hypertension, Non Communicable Chronic Diseases
- Trial name
- NCT07098065
- Testing
- Graphical health warnings, Graphical health warnings plus pharmacist-led counselling, Routine pharmacy services (no intervention)
- Where
- Bangladesh
- Volunteers
- 3,400 people
- Sponsor
- Hitotsubashi University
Cardiovascular Diseases (CVD), Type 2 Diabetes
Epigenetics and NCD Prevention in Kazakhstan: Personalized Approaches and Biological Age Prediction
This study aims to enhance personalized and preventive care for non-communicable diseases (NCDs) in Kazakhstan by examining epigenetic factors, predicting biological age and reproductive function using machine learning, and…
- Conditions
- Cardiovascular Diseases (CVD), Type 2 Diabetes, Chronic Respiratory Diseases, Obesity (Disorder)
- Trial name
- NCT06953180
- Testing
- Genetic: DNA analysis
- Where
- Kazakhstan
- Volunteers
- 6,720 people, healthy volunteers welcome
- Sponsor
- Asfendiyarov Kazakh National Medical University