Clinical trials: Non-erosive Reflux Disease, open to volunteers
Symptomatic Non-erosive Gastroesophageal Reflux Disease
A Study to Evaluate the Efficacy and Safety of Vonoprazan 10 mg Compared to Placebo for Relief of Episodic Heartburn in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease Through 24 Weeks
The main objective is to assess the efficacy of vonoprazan (10 mg as needed) compared to placebo (as needed) in relief of episodic heartburn at 2 hours that is sustained for 24 hours over 12 weeks of treatment in participants…
- Trial name
- NCT07752407
- Testing
- Vonoprazan
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Phathom Pharmaceuticals, Inc.
GERD (Gastroesophageal Reflux Disease), NERD
New Topical tReatment Options for Symptomatic patiEnts With Nonerosive gastroesophageaL Reflux dIsease (The RELIEF Trial)
The goal of this randomized, double-blind, single-center clinical trial RELEIF is to learn if medical devices work to decrease symptoms of gastroesophageal reflux disease (GERD) in adults' patients.
- Conditions
- GERD (Gastroesophageal Reflux Disease), NERD, Heartburn, Regurgitation, Gastric
- Trial name
- RELIEF (NCT07624383)
- Testing
- Esophageal barrier medical device
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Cellmedis
Gastroesophageal Reflux Disease, GERD
Real-life Study of Changes of Gastroesophageal Reflux Disease Manifestations Due to Behavioural and Diet Adherence
This study is aimed to investigate the role of long-term diet adherence on manifestations of gastroesophageal reflux disease
- Conditions
- Gastroesophageal Reflux Disease, GERD, Gastroesophageal Erosion, Erosive Esophagitis
- Trial name
- NCT04255693
- Testing
- diet adherence, No diet adherence, Change in physical activity
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- Federal State Budgetary Scientific Institution
Non-Erosive Gastroesophageal Reflux Disease (NERD)
Mirgeal® Gel as Add-on Therapy to Esomeprazole in Adults With Non-Erosive Gastroesophageal Reflux Disease
Gastroesophageal reflux disease (GERD) is a common condition that can cause symptoms including heartburn, acid regurgitation, sour taste and other upper gastrointestinal complaints.
- Trial name
- NCT07790549
- Testing
- Esomeprazole 20mg, Mirgeal® Gel (manufacturer: PharmExtracta S.p.A.)
- Where
- 2 sites in Italy
- Volunteers
- 140 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Nocturnal Symptoms of GERD, Sleep Disorders in GERD
QUality of Sleep Improvement With Evening Topical Therapy for Non-Erosive Gastroesophageal Reflux Disease (The QUIET Trial)
The goal of this randomized, double-blind, single-center clinical trial is to learn if medical devices work to decrease nocturnal symptoms of GERD gastroesophageal reflux disease in adults' patients and improve sleeping time…
- Conditions
- Nocturnal Symptoms of GERD, Sleep Disorders in GERD, GERD (Gastroesophageal Reflux Disease), Non-Erosive Gastro-Esophageal Reflux Disease
- Trial name
- QUIET (NCT07700342)
- Where
- 2 sites in Poland
- Volunteers
- 50 people
- Sponsor
- Cellmedis
Erosive Esophagitis, Heartburn
A Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring
The main objective of the study is to compare the maternal, fetal, and infant outcomes of pregnant women who are exposed to vonoprazan during pregnancy with outcomes of an internal comparison cohort of pregnant women who are…
- Conditions
- Erosive Esophagitis, Heartburn, Symptomatic Non-erosive Gastroesophageal Reflux Disease, Helicobacter Pylori Infection
- Trial name
- NCT06660342
- Testing
- Vonoprazan
- Where
- United States
- Volunteers
- 728 people
- Sponsor
- Phathom Pharmaceuticals, Inc.
Non-erosive Reflux Disease (NERD)
Transcutaneous Electrical Acustimulation (TEA) for the Treatment of Non-Erosive Gastroesophageal Reflux Disease (NERD)
This multicenter study aims to evaluate whether Transcutaneous Electrical Acustimulation (TEA) is effective in treating Non-Erosive Gastroesophageal Reflux Disease (NERD).
- Trial name
- NCT07572708
- Testing
- Transcutaneous Electrical Acustimulation
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Ningbo Medical Center Lihuili Hospital
Non-erosive Reflux Disease (NERD)
Effect of Inspiratory Muscle Training on Symptom Severity and Quality of Life in Non-Erosive Reflux Disease
The goal of this clinical trial is to learn if inspiratory muscle training (IMT) works to treat on clinical symptom severity and quality of life in patients with Non-erosive reflux disease (NERD).
- Trial name
- NCT07584096
- Testing
- Inspiratory Muscle Training (IMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Izmir University of Economics
Maintenance of Healed Erosive Gastroesophageal Reflux Disease (ERD)
Phase 3 Study of JP-1366: Efficacy and Safety of JP-1366 as Maintenance Therapy in Subjects With Healed Erosive Esophagitis
This study aims to evaluate the Efficacy and Safety of JP-1366 as Maintenance Therapy in Subjects with Healed Erosive Esophagitis
- Trial name
- NCT07732075
- Testing
- JP-1366 10 mg, Lansoprazole 15mg
- Volunteers
- 384 people
- Sponsor
- Onconic Therapeutics Inc.
Non-erosive Gastroesophageal Reflux Disease
Phase 3 Study of JP-1366: Efficacy and Safety of JP-1366 in Patients With Non-erosive Gastroesophageal Reflux Disease
This study aims to evaluate the efficacy and safety of JP-1366 in Patients with NERD
- Trial name
- NCT07160790
- Volunteers
- 321 people
- Sponsor
- Onconic Therapeutics Inc.
Non-erosive Reflux Disease (NERD)
Clinical Efficacy Evaluation of Chaizhi Hewei Decoction in the Treatment of Non-Erosive Reflux Disease With Liver-Stomach Disharmony Syndrome
This study focuses on patients with NERD (gastroesophageal reflux disease) and liver-gallbladder disharmony syndrome as its research subjects.
- Trial name
- NCT07518420
- Testing
- Chaizhi Hewei Decoction
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences