Clinical trials: Non-intubated Anesthesia
Comparison of Hemodynamics and Respiratory Function Between Ciprofol and Propofol in Elderly Patients Undergoing Non-intubated General Anesthesia
Comparison of Hemodynamics and Respiratory Function Between Ciprofol and Propofol in Elderly Patients Undergoing Non-intubated General Anesthesia
At the initiation of induction for non-intubated general anesthesia, ciprofol or propofol will be administered intravenously at a rate of 10 mL/min.
- Trial name
- NCT07670923
- Testing
- Propofol Injection, Ciprofol Injection
- Where
- China
- Volunteers
- 108 people
- Sponsor
- General Hospital of Ningxia Medical University
Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice
Feasibility and Safety of Supraglottic Oxygen Delivery Via an Endotracheal Tube for Non-intubated ERCP Anesthesia: A Two-Stage Phase II Clinical Study
Endoscopic retrograde cholangiopancreatography (ERCP) is a technique for evaluating the bile duct, pancreatic duct, and ampulla.
- Conditions
- Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice, Pancreatitis, Cholelithiasis
- Trial name
- NCT07051980
- Testing
- Supraglottic Oxygen Delivery via an Endotracheal Tube
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Zhejiang University
Pericardial Effusion, Inflammatory Response After Surgery
Anesthesia Management, Inflammatory Response and Recovery After Non-intubated VATS Pericardial Window
Non-intubated video-assisted thoracoscopic surgery (NIVATS) is performed under spontaneous ventilation and avoids tracheal intubation and one-lung mechanical ventilation.
- Conditions
- Pericardial Effusion, Inflammatory Response After Surgery, Postoperative Complications, Procedural Sedation and Analgesia
- Trial name
- RNIVATS (NCT07800767)
- Testing
- Systemic opioid-based analgesia during NIVATS, Thoracic regional analgesia during NIVATS
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Breast Neoplasms, Pain
Regional Anesthesia in Breast Surgery
There is a trend that breast surgery can be done with peripheral nerve blockade and intravenous sedation, which reduces the side effects of general anesthesia such as nausea and vomiting, intubation discomfort and postoperative…
- Conditions
- Breast Neoplasms, Pain, Analgesia, Regional Anesthesia
- Trial name
- NCT04629612
- Testing
- Regional anesthesia
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Non Small Cell Lung Cancer
Clinical Trial of Thoracoscopic Lobecotmy Under Spontaneous Ventilating Anesthesia
With the development of video-assisted thoracoscopic surgery (VATS) techniques and technology for anesthesia control, non-intubated anesthesia with spontaneous ventilation has been widely applied in VATS.
- Trial name
- NCT03432637
- Testing
- spontaneous ventilation, intubated anesthesia with single-lung mechanical ventilation
- Where
- 2 sites in China
- Volunteers
- 450 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Esophageal Cancer (EsC)
Non-intubated Versus Intubated Anesthesia in Thoracoscopic Esophagectomy for Esophageal Cancer
This is a prospective, single-center, non-inferiority randomized controlled trial designed to evaluate the perioperative safety and feasibility of non-intubated spontaneous ventilation anesthesia (NIV) compared to conventional…
- Trial name
- NCT07104838
- Testing
- Non-intubated spontaneous ventilation anesthesia
- Volunteers
- 500 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Pleural Effusion, Malignant, Pleural Mesothelioma
A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia
Video-assisted thoracic surgery (VATS) is usually performed with general anesthesia and single lung ventilation. However, performing thoracic surgery under awake regional anesthesia has several potential advantages including…
- Conditions
- Pleural Effusion, Malignant, Pleural Mesothelioma, Pleural Empyema, Pulmonary Diseases or Conditions
- Trial name
- VATS (NCT05077111)
- Testing
- Thoracic Epidural Anesthesia, General Anesthesia with One Lung Ventilation
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mohamed Reda Ashour
This Study Evaluates the Effects of Different Fascial Plane Blocks on Intraoperative Anesthesia and Analgesic Consumption in Non-intubated VATS Procedures
Comparison of SPSIP Block and SAP Block in Non-Intubated Uniportal VATS.
Comparison of Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block in Uniportal Video-Assisted Thoracoscopic Surgery Without Intubation Single-port video-assisted thoracoscopic surgery without…
- Trial name
- NCT07440199
- Testing
- Serratus Anterior Plane Block (SAPB) group, Serratus posterior superior intercostal plane block group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Firat University
Pulmonary Nodules, Early Stage Lung Cancer (I and II)
Tubeless Strategy for Enhanced Recovery After Sublobar Resection
This is a prospective, randomized controlled clinical trial conducted at a single center. The study aims to evaluate whether a "tubeless" strategy can enhance recovery for patients undergoing minimally invasive thoracoscopic…
- Conditions
- Pulmonary Nodules, Early Stage Lung Cancer (I and II), Thoracoscopic Surgery, Sublobar Resection
- Trial name
- NCT07409129
- Testing
- Laryngeal Mask Airway, Thoracic Paravertebral Block with Local Anesthetic, Non-intubated Anesthesia
- Where
- China
- Volunteers
- 138 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Thoracic Surgery, Anesthesia
A Randomized, Controlled Clinical Trial Comparing Remimazolam Besylate Combined With Alfentanil Versus Propofol Combined With Alfentanil for Anesthesia in Thoracic Surgery
Title: A Clinical Study Comparing Two Anesthesia Methods for Chest Surgery Why is this study being done? Chest surgeries (like lung surgery) require safe and stable anesthesia.
- Conditions
- Thoracic Surgery, Anesthesia, Non-intubated Anesthesia
- Trial name
- RAA-TS (NCT07347496)
- Testing
- Remimazolam Besylate for Injection, Propofol, Alfentanil Hydrochloride Injection
- Volunteers
- 50 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Mediastinal Neoplasm, VATS
Tubeless VATS for Mediastinal Neoplasm
In recent year, non-intubated anesthesia had emerged as an available and promising alternative for thoracic procedure. However, its safety and feasibility in video-assisted thoracoscopic surgery (VATS) for mediastinal neoplasm…
- Conditions
- Mediastinal Neoplasm, VATS, Tubeless, Non-intubated Anesthesia
- Trial name
- NOVA-02 (NCT07065604)
- Testing
- Non-intubated VATS for mediastinal neoplasm, Intubated VATS for mediastinal neoplasm
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Shuben Li
Pulmonary Nodules, Lung Neoplasms
Non-intubated Versus Intubated Anesthesia for Thoracoscopic Sublobar Resection
This is a large clinical study that compares two different types of anesthesia for patients undergoing a specific kind of minimally invasive lung surgery (thoracoscopic sublobar resection) to remove small, early-stage lung…
- Conditions
- Pulmonary Nodules, Lung Neoplasms, Thoracic Surgery
- Trial name
- NIVA-TSLR (NCT07395375)
- Testing
- Non-intubated Anesthesia, Conventional Intubated General Anesthesia, Laryngeal Mask Airway (LMA)
- Where
- China
- Volunteers
- 1,600 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Phrenic Nerve Paralysis
the Clinicaltrail of the Effection Which of Phrenic Block Using in Non-intubated Video-assisted Thoracoscopic Surgery
Putting 80 patients divided into group S（non-intubated general anesthesia combine with Paravertebral blocks、surface spray anesthesia and Vagus block） and group D（non-intubated general anesthesia combine with Paravertebral…
- Trial name
- NCT03653494
- Testing
- phrenic block, no phrenic block
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shenzhen People's Hospital
Obesity, Obstructive Sleep Apnea
Micro-stream Capnography in Non-intubated Lean and Obese Patients With and Without Obstructive Sleep Apnea
The purpose of this study is to compare the accuracy of EtPCO2 measurements taken with a nasal cannula using the Microcap (Oridion Capnography Inc., Needham, MA) micro-stream device and the TG-920 main-stream device (Nihon…
- Trial name
- NCT00653471
- Testing
- Microcapmicro-stream device with Smart CapnoLine Plus, Microcap micro-stream device with CapnoLine, TG-920 main-stream device (Nihon Kohden, Tokyo, Japan).
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Cleveland Clinic
Heart Transplant
Non-Intubated Anesthesia for Adult Heart Transplantation
This prospective, multicenter, randomized controlled trial aims to evaluate whether non-intubated spontaneous ventilation anesthesia (NISVA) supported by a supraglottic airway can reduce cardiopulmonary complications and promote…
- Trial name
- NISVA-HTx (NCT07758894)
- Testing
- Non-Intubated Spontaneous Ventilation Anesthesia, Conventional Anesthesia, Standardized Perioperative Anesthetic and Analgesic Medication Regimen
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Ventilatory Depression
Correlation of ETCO2 to PaCO2 Measured by Sentri Nasal Cannula
Sampling end tidal gas via nasal prong has been shown to be a noninvasive and reliable method of monitoring end-tidal CO2 in spontaneously breathing patients.
- Trial name
- NCT03374644
- Testing
- SentriTM ETCO2 adult nasal cannula
- Volunteers
- 40 people
- Sponsor
- University of Malaya
Tracheal Disease, Airway Disease
Tubeless Tracheal and Carinal Reconstruction
In recent year, non-intubated anesthesia had emerged as an available alternative for thoracic procedure. Whether non-intubated tracheal/carinal reconstruction confers distinct perioperative advantages over the conventional…
- Trial name
- NOVA-01 (NCT07065565)
- Testing
- non-intubated tracheal and carinal reconstruction, intubated tracheal and carinal reconstruction
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Shuben Li
Lung Diseases, Total Intravenous Anesthesia
Effects of Adding Different Drugs for Preventing Cough Induced by Bronchoscopic Spraying of Local Anesthetics
Cough is the most unwanted response during bronchoscopic interventions for hemodynamic instability, hypoxemia, and interruption of interventions.
- Conditions
- Lung Diseases, Total Intravenous Anesthesia, Bronchoscopic Interventions
- Trial name
- NCT05072236
- Testing
- bronchoscopic insertion
- Where
- Taiwan
- Volunteers
- 108 people
- Sponsor
- National Taiwan University Hospital
Lung Diseases, Interstitial
NIVATS Versus IGAVATS: a Pilot Trial Addressing Biopsy Quality in Undetermined Interstitial Lung Diseases
The main objective of this study is to compare two independent groups of patients requiring lung biopsy for undetermined interstitial lung disease (ILD) in terms of diagnostic confidence as determined by histologists.
- Trial name
- NIVATS-2 (NCT05722340)
- Testing
- Non-intubated video-assisted thoracic surgery (NIVATS) for lung biopsy, Intubated general anaesthesia video-assisted thoracic surgery (IGAVATS) for lung biopsy
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Montpellier