Clinical trials: Non-invasive
Diabete Mellitus, Medical Device
Non-invasive Glucose Measurement With Raman Technology in Patients With Type 1 and Type 2 Diabetes
The study was established to collect data and reference measurements in order to establish calibration models for the Prototype 0.3
- Trial name
- NCT03781232
- Testing
- Prototype 0.3
- Where
- 2 sites in Germany
- Volunteers
- 47 people
- Sponsor
- RSP Systems A/S
Superficial Bladder Cancer
Study of Immediate Post-Operative Intravesical Instillation of Chemophase® in Patients With Superficial Bladder Cancer
The purpose of this research study is to test the safety and tolerability of an experimental drug, Chemophase, a combination of recombinant human hyaluronidase, (an investigational synthetic enzyme also known as rHuPH20), and…
- Trial name
- IPOP (NCT00782587)
- Testing
- Chemophase
- Where
- 5 sites in United States
- Volunteers
- 14 people
- Sponsor
- Halozyme Therapeutics
In-stent Restenosis, Stent Fracture
Pilot Study of the α Prototype NIMBLE System: Feasibility, Safety, and Initial Performance in Non-Invasive Detection of Coronary In-Stent Restenosis
The NIMBLE-I study is a prospective, unicentric, single arm, feasibility clinical trial designed to evaluate a novel medical device for the non-invasive monitoring of coronary stents.
- Conditions
- In-stent Restenosis, Stent Fracture, Stent Complication
- Trial name
- NIMBLE-I (NCT06968858)
- Testing
- NIMBLE test
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nimble Diagnostics S.L.
Knee Osteoarthritis
Veteran Affairs Osteoarthritis Knee Study
A clinical study at the Dallas Veterans Affairs, is being proposed to test the efficacy of a novel electrical stimulation platform named the Pro-Sport Ultra® device by AVAZZIA to reduce pain and increase activity level in…
- Trial name
- NCT04698733
- Testing
- BEST™ HVPC microcurrent electrical stimulation Pro-Sport Ultra® device
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Avazzia, Inc
Glaucoma Eye, Macular Degeneration
Retinal Oxygenation Estimation Trial With Mantis Photonics Hyperspectral Camera
An explorative study of the Mantis Photonics hyperspectral camera for retinal imaging and estimation of retinal oxygenation. Primary objective: To evaluate the performance of the hyperspectral camera for non-invasive retinal…
- Conditions
- Glaucoma Eye, Macular Degeneration, Macula Abnormality, Retinal Detachment
- Trial name
- NCT05566626
- Testing
- Hyperspectral retinal image, Mydriacyl Ophthalmic Product
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mantis Photonics AB
Wrinkle
Safety and Efficacy of the BTL-785F Device for Non-invasive Reduction of Wrinkles
This study will evaluate the clinical safety and the performance of the BTL-785F system for non-invasive treatment of facial wrinkles. The study is a multicenter single-arm, open-label, interventional study.
- Trial name
- NCT05476211
- Testing
- BTL-785F
- Where
- Bulgaria
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Cardiac Output, Low, Cardiac Output, High
Comparing Cardiac Output Measurements Using a Wearable, Wireless, Non-invasive PPG-Based Device to a Swan Ganz Catheter
Invasive pulmonary capillary wedge pressure measurements using a Swan-Ganz catheter (SGC) is considered the gold standard for cardiac output (CO) monitoring.
- Conditions
- Cardiac Output, Low, Cardiac Output, High, Congestive Heart Failure
- Trial name
- NCT04955184
- Testing
- non-invasive monitoring
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Biobeat Technologies Ltd.
Chronic Low Back Pain
The Enso Study for Chronic Low Back Pain
Enso is a portable device for the treatment of chronic and acute types of musculoskeletal pain. This study is being designed as a double-blinded, sham-controlled randomized clinical trial.
- Trial name
- EPS (NCT03320863)
- Testing
- Enso device
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Thimble Bioelectronics, Inc.
Osteoarthritis
A Study to Evaluate the DePuy Minimally Invasive Unicompartmental Knee
The primary purpose of this investigation is to evaluate the surgical performance of the DePuy Minimally Invasive (Preservation) Unicompartmental Knee and Instrumentation in a Multi-centre setting.
- Trial name
- NCT00734084
- Testing
- Preservation Unicompartmental Knee
- Where
- Australia
- Volunteers
- 247 people
- Sponsor
- DePuy International
Coronary Artery Disease
Non-invasive Point-of-care Diagnosis Using Machine Learning and Signal Analytics to Transform Early Detection of Heart Disease
This study is designed as a repository study to collect resting cardiac phase signals and subject meta data from eligible subjects using the Phase Signal Recorder (PSR) prior to coronary angiography.
- Trial name
- IDENTIFY (NCT03864081)
- Testing
- Phase Signal Recorder
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- Analytics For Life
Heart Failure
Correlation of Non-invasive Assessment, Using C.A 2.0 Device, Versus Invasive Assessment of LVEDP
The purpose of the study is to determine the accuracy of non-invasive assessment of LVEDP using the investigational device C.A 2.0.
- Trial name
- NCT02099448
- Where
- Israel
- Volunteers
- 41 people
- Sponsor
- CorAlert Ltd.
Migraine With Aura
Efficacy and Safety of TMS for the Preemptive Treatment of Migraine With Aura
Assess safety and efficacy of Transcranial Magnetic Stimulation (TMS) for the treatment of migraine with aura The hypothesis is that TMS treatments delivered to the occipital cortex of the brain can stop or interrupt the…
- Trial name
- NCT00449540
- Testing
- Active Transcranial Magnetic Stimulation (TMS) Device
- Where
- 14 sites in United States
- Volunteers
- 201 people
- Sponsor
- Neuralieve
Epilepsy
Tonicity Monitor For Epilepsy and Hypertonic Disorders
Epilepsy is an episodic disorder which can result in recurrent seizures often associated with hypertonia (muscle stiffening) and myoclonia (involuntary muscle jerking).
- Trial name
- NCT02110589
- Testing
- Epidetect
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Vikel Ltd
Non-Small Cell Lung Cancer
Noninvasive vs. Invasive Lung Evaluation
Tumor derived cell free DNA (cfDNA) is increasingly used in the clinic to obtain genotype information about lung cancer, but its concordance with concurrent tumor-derived sequenced data is not known.
- Trial name
- NILE (NCT03615443)
- Testing
- Guardant360
- Volunteers
- 306 people
- Sponsor
- Guardant Health, Inc.
Blood Pressure
B40 Non-Invasive Blood Pressure Equivalency Study
The purpose of this study is to demonstrate equivalency of the GE Healthcare B40 Patient Monitor noninvasive blood pressure (NIBP) parameter compared to the reference device.
- Trial name
- NCT01546285
- Testing
- Blood Pressure Readings on B40 Patient Monitor
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Chronic Low Back Pain (CLBP)
Non Invasive Brain Stimulation Treatment for CLBP
This trial is designed to preliminary evaluate the efficacy and safety of NIBS system for treatment of chronic low back pain (CLBP) (over 6 months).
- Trial name
- NIBSTCLBP (NCT02615418)
- Testing
- NIBS system for evaluation and treatment utilizing non invasive brain stimulation
- Volunteers
- 60 people
- Sponsor
- NIBS NeuroScience Technologies
Sepsis, Bacteremia
Safety and Efficacy of MBI 226 for the Prevention of Central Venous Catheter-Related Bloodstream Infections
Central venous catheters (CVCs) are used in patient care for such purposes as the administration of medication, fluids, blood products and for functions such as hemodialysis and plasmapheresis.
- Conditions
- Sepsis, Bacteremia, Fungemia
- Trial name
- NCT00027248
- Testing
- MBI 226
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- BioWest Therapeutics Inc
Alzheimer s Disease
Precuneus Mapping With Sinaptistim® (an Investigational TMS-EEG System) in Mild to Moderate AD Patients
Transcranial magnetic stimulation (TMS), electroencephalography (EEG), and combined TMS-EEG approaches have been used in human research to characterize cortical excitability and network-level neurophysiologic responses.
- Trial name
- NCT07841808
- Testing
- TMS-EEG
- Volunteers
- 30 people
- Sponsor
- Sinaptica Therapeutics, Inc.
Peri-Implantitis
Non-invasive Solution for Periodontal and Peri-implant Diseases (INPERIO)
DESCRIPTION: The Investigational Product "A-Ce toughened TZP nanocomposite implant" is a Medical Device (MD) intended for the dental rehabilitation of edentulous sites with fixed prosthesis.
- Trial name
- INPERIO (NCT03977714)
- Testing
- Zirconia implants with G3-coated abutments (test implants and abutments), Zirconia implants with control abutments (test implants, negative control abutments), Titanium implants with G3-coated abutments (control implants, test abutments)
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Nanoker Research S.L.
Migraine
A Randomized, Multicenter, Study for the prEvention and Acute Treatment of Migraine (REAL)
This is a randomized study for the prevention and acute treatment of migraine using open label nVNS and standard of care versus standard of care. .
- Trial name
- REAL (NCT03787238)
- Testing
- non-invasive vagus nerve stimulation
- Where
- 17 sites in Denmark, Germany and 3 more
- Sponsor
- ElectroCore INC