Clinical trials: Non-invasive
Diabetic Foot Ulcer
Non-Invasive Testing to Evaluate Wound Healing in Diabetes
Normal group: We will collect normative data from healthy individuals to include baseline data, screening, and images. Up to 500 people will be enrolled and can include normal healthy volunteers, staff and students/trainees.
- Trial name
- NCT04232631
- Testing
- SnapshotNIR, Kent Imaging
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Early Gastric Cancer
Detection of Methylated Reprimo in Plasma for Asymptomatic Gastric Cancer
In this proposal the investigators aim to develop a commercial kit to be used in primary screening and non-invasive triage for early detection of gastric cancer.
- Trial name
- DEMRAC (NCT01774266)
- Where
- Chile
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Brain Concussion
Mild Traumatic Brain Injury Discrimination
Evaluation of the utility of a multi-modal assessment tool in distinguishing between individuals with and without a history of mild traumatic brain injury.
- Trial name
- MTBID (NCT02453958)
- Testing
- Multi-modal assessment system
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Empirical Technologies Corporation
Neuromuscular Diseases, Neurologic Disorder
Multisystem and Autonomic Complications of NMD on Long-term NIV
This exploratory observational study evaluates autonomic function using measures including heart rate variability in adults with childhood-onset neuromuscular and neurological disorders (NMD) who use non-invasive ventilation…
- Trial name
- NCT04100993
- Testing
- No intervention used
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Cardiac Diseases
Non-Invasive Determination of Cardiac Output by Electrical Velocimetry
The cardiac output (CO) is an important parameter in the diagnosis and therapy of cardiac diseases. The current standard methods for the determination of the CO, however, are either invasive (e.g.
- Trial name
- NCT00945048
- Testing
- electrical velocimetry, inert gas rebreathing, spirometry
- Where
- Germany
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Crohn Disease
Non-invasive Approaches to Identify the Cause of Fatigue in Inflammatory Bowel Disease Patients.
Crohn's disease (CD) presents with severe symptoms, but fatigue is a very predominant symptom that negatively impacts upon quality of life.
- Trial name
- IBD Fatigue (NCT03670693)
- Testing
- Muscle strength and fatigue assessment, Dual-energy X-ray absorptiometry (DEXA scan), Supine cardiorespiratory fitness assessment
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Motor Skill Acquisition in Healthy Older Adults
Training in Combination With Non-invasive Brain Stimulation
The goal of this study is to investigate the impact of non-invasive brain stimulation on motor skill acquisition in healthy individuals.
- Trial name
- TrainStim (NCT07059533)
- Testing
- Verum
- Where
- Switzerland
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Friedhelm Hummel
Secondary Infertility
Non-invasive Preimplantation Genetic Testing for Aneuploidies Using Cell-free DNA in Spent Culture Media
Analysis of embryonic cell-free DNA (cfDNA) present in the spent culture media (SCM) is a non-invasive alternative for preimplantation genetic testing for aneuploidies (PGT-A) that avoids the technical challenges and limitations…
- Trial name
- niPGT-A (NCT04711239)
- Testing
- PGT-A / niPGT-A
- Volunteers
- healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Cachexia
Development of a Non-invasive Assessment of Skeletal Muscle Loss in Cancer Patients
The long-term objective of this research is to develop a non-invasive approach for early assessment of which patients are at high risk for future development of skeletal muscle atrophy.
- Trial name
- NCT00994669
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Non-invasive Hepatocellular Carcinoma
Exploring the Knowledge, Attitudes, Behaviors and Perceived Barriers of Hepatologists Towards Non-invasive Hepatocellular Carcinoma Prediction Models in Hepatitis C Patients Who Achieved Sustained Virological Response Following Direct Acting Antivirals Therapy
This study aims to assess the knowledge, attitudes, and behaviors (KAB) of hepatologists regarding different models used to predict hepatocellular carcinoma (HCC) in patients with chronic hepatitis C (HCV) who achieved sustained…
- Trial name
- NCT06872047
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
Fat Reduction, Muscle Tone Increased
Electrical Muscle Stimulation with 1064 Nm Diode Laser and RF/PEMF for Non-invasive Body Contouring and Fat Reduction.
Multi-center, three-arm, randomized, evaluator-blinded study of electrical muscle stimulation (EMS) and/or 1064 nm diode laser, pulsed electromagnetic field (PEMF) and vacuum assisted radio frequency (RF) using the Venus Bliss…
- Trial name
- NCT05256771
- Testing
- EMS, 1064 nm diode laser, RF/PEMF
- Where
- 3 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Aneuploidy, Infertility
Nuclear Magnetic Resonance for Embryo Ploidy Selection
This study aims to validate the embryo culture medium analysis by nuclear magnetic resonance spectroscopy, as a faster and less-costly alternative to preimplantation genetic test for aneuploidy which could significantly enhance…
- Trial name
- NCT05488236
- Testing
- Nuclear magnetic resonance analysis of embryo culture medium
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Atherosclerosis, Cardiovascular Disease
A Prospective Study on Predictive Value of Non-Invasive Atherosclerotic Measurements in Elderly Chinese
The purpose of this study is to determine whether non-invasive atherosclerotic measurements (baPWV, IMT, FMD, CACS, ABI) are valuable predictors for cardiovascular events in elderly.
- Trial name
- NCT01208116
- Testing
- Cardiovascular events
- Where
- China
- Volunteers
- 1,290 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University General Hospital
Stroke
Impact of Non-invasive Brain Stimulation on Motor Recuperation
tDCS (transcranial direct current stimulation) will be used in chronic stroke patients to improve a variety of functions with superior or inferior limb.
- Trial name
- NCT01544699
- Testing
- tDCS (ELDITH)
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Diabetes
Raman Spectroscopy-Based Non-Invasive Blood Glucose Detection
Diabetes is a chronic metabolic disease that is widely prevalent globally, with its incidence rate continuously increasing, posing significant challenges to patient health and public health systems.
- Trial name
- Raman Glucose (NCT07311421)
- Testing
- Raman spectroscopy for blood glucose measurement
- Where
- 2 sites in China
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University
Healthy
Development of Novel Non-invasive Inflammometry Following Lipopolysaccharide, Endotoxin (LPS) Challenge in Healthy Volunteers
The aim of this study is to further profile and develop the Lipopolysaccharide, endotoxin (LPS) challenge models (both by instillation and inhalation) by investigating the utility of various non-invasive monitoring methods.
- Trial name
- NCT03044327
- Testing
- LPS challenge
- Where
- Germany
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Bronchial Asthma, Pulmonary Cystic Fibrosis
Pulmonary Condensate: Non-invasive Evaluation of Pulmonary Involvement in Asthma and Cystic Fibrosis.
Exhaled breath condensate (EBC) represents a rich source for countless biomarkers that can provide valuable information about respiratory as well as systemic diseases.
- Trial name
- NCT04157361
- Testing
- Collection of breath condensate
- Where
- Czechia
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- The Institute of Molecular and Translational Medicine, Czech Republic
Improvement of Abdomen Appearance
Effect of the BTL-899 Therapy for Non-invasive Lipolysis and Circumference Reduction of Abdomen
The study is a prospective open-label single-arm study that includes three treatment procedures and four follow-up visits.
- Trial name
- NCT03270150
- Testing
- BTL-899
- Where
- Bulgaria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Cardiac Arrest, Cognitive Impairment
Modifying Working Memory With Brain Stimulation
The investigators want to investigate the effect of rTMS on working memory measured by the N-back task. This is a single case experimental design, ABAB.
- Trial name
- BROCA-NIBS (NCT06119620)
- Testing
- intermitted theta burst stimulation
- Where
- Netherlands
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Anemia
Wearable Device-Based Screening for Anemia Risk
Anemia is a common condition, but it often goes undiagnosed because confirming it requires a venous blood test. This study looks at whether a commercially available wrist-worn smartwatch can help identify people who may have…
- Trial name
- WEAR-ANEMIA (NCT07796542)
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
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