Clinical trials: Non-invasive
Colon Cancer, Rectal Cancer
The Safety and Feasibility of MONOFIX on Fascial Closure of Mid-line Wound After Minimally Invasive Colorectal Cancer Surgery
This clinical trial aims to evaluate the safety and feasibility of mid-line fascial suturing using MONOFIX sutures in patients undergoing minimally invasive surgery for colorectal cancer.
- Conditions
- Colon Cancer, Rectal Cancer, Colon Adenocarcinoma, Rectal Adenocarcinoma
- Trial name
- NCT05872334
- Testing
- Monofix
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Samsung Medical Center
Breast Cancer, Invasive Breast Cancer
Window of Opportunity Trial of Entinostat in Patients With Newly Diagnosed Stage I-IIIC,TNBC
This study is investigational and is not designed to treat cancer. In other words, the study drug, entinostat, is not being given to treat cancer.
- Conditions
- Breast Cancer, Invasive Breast Cancer, ER-Negative PR-Negative HER2-Negative Breast Cancer
- Trial name
- NCT03361800
- Testing
- Entinostat
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Blood Pressure, Heart Failure
Wrist Worn Blood Pressure Measurement
In this study, the investigators are testing the accuracy of a wrist-worn measurement device by comparing its blood pressure measurement to arterial line (A-line) blood pressure monitors.
- Conditions
- Blood Pressure, Heart Failure, Advanced Heart Failure, Heart Failure，Congestive
- Trial name
- NCT03919136
- Testing
- Wrist-worn measurement device (LiveMetric)
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- LiveMetric S.A.
Extubation in Intensive Care Unit
EXtubation With SUctioning or With Positive End-Expiratory Pressure in Intensive Care Unit
Extubation in intensive care unit is a risky situation. Its failure is associated with an increase in the duration of mechanical ventilation and high morbidity and mortality.
- Trial name
- EXSUPEEP (NCT05147636)
- Testing
- Extubation with PEEP, Endotracheal Aspiration
- Where
- 11 sites in France
- Volunteers
- 425 people
- Sponsor
- Centre Hospitalier de Bourg en Bresse
Suspected CSF Shunt Obstruction
ShuntCheck-Micro-Pumper Pediatric Clinical Outcomes Study
Primary objective is to demonstrate that data collected from ShuntCheck-Micro-Pumper (SCMP) testing results can be used in conjunction with imaging to diagnose shunt patency or obstruction in pediatric/adolescent subjects…
- Trial name
- NCT01881711
- Testing
- ShuntCheck-Micro-Pumper (SCMP), Imaging
- Where
- 11 sites in United States
- Volunteers
- 400 people
- Sponsor
- NeuroDx Development
Metabolic Syndrome
Vagal Nerve Stimulation as Therapeutic Approach on Metabolic Syndrome
Participants were randomly assigned to two groups prior to their second visit: the Vagus nerve stimulation group (VNS) and the circuit training program.
- Trial name
- NCT05785117
- Testing
- Vagal Stimulation, Circuit training program
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Rana Elbanna
Angina Pectoris, Arteriosclerosis
Dan-NICAD - Danish Study of Non-Invasive Diagnostic Testing in Coronary Artery Disease
1. The primary purpose of this study is to determine the diagnostic accuracy of the CADscore System, a new danish technology that records sounds from turbulence of bloodflow in the coronary vessels. And secondary: 1.
- Conditions
- Angina Pectoris, Arteriosclerosis, Coronary Artery Disease, Myocardial Ischemia
- Trial name
- NCT02264717
- Testing
- SPECT, Cardiac MRI
- Where
- 3 sites in Denmark
- Volunteers
- 1,676 people
- Sponsor
- University of Aarhus
Respiratory Insufficiency
Brain Natriuretic Peptide (BNP) Levels in Patients in Non Invasive Mechanical Ventilation
The purpose of the study is to evaluate variation of BNP in non invasive mechanical ventilated patients with severe acute respiratory failure.
- Trial name
- NCT00453726
- Testing
- Non invasive mechanical ventilation
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Ospedale S. Giovanni Bosco
Respiratory Insufficiency
Physiological Response to Heliox21 and Air O2
This is a non-commercial study to explore the use of Heliox21 in a new patient cohort. The fundamental aim is to assess the therapeutic benefits of Heliox21 and practicalities of gas delivery in patients who require non-invasive…
- Trial name
- NCT01498432
- Testing
- Heliox21, Air O2
- Where
- United Kingdom
- Volunteers
- 38 people
- Sponsor
- University College, London
Blood Pressure
ArteVu Blood Pressure Accuracy Study
A continuous noninvasive blood pressure monitoring digital fingertip clip device, the ArteVu, will be compared against the reference arterial catheter during operation.
- Trial name
- ARTEVU (NCT05105204)
- Testing
- ArteVu
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Cardio Ring Technologies, Inc. Taiwan Branch
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Comparison of Non-invasive Oxygenation Strategies in Patients Admitted for Covid-19 Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome (ARDS) is the main clinical presentation of SARS-CoV-2 (Covid-19) infected patients admitted in Intensive Care Unit (ICU).
- Trial name
- SONIC-19 (NCT04725084)
- Testing
- Use of High Flow Nasal Cannula alone, Use of Non-invasive Ventilation, Use of Continuous Positive Airway Pressure
- Where
- 4 sites in France
- Volunteers
- 355 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Cerebrovascular Disorders, Healthy
Non-Invasive Electrical Stimulation of the Human Brain
This study is designed to allow researchers to use transelectrical stimulation to explore the function of the human nervous system and improve diagnosis of neurological disorders.
- Conditions
- Cerebrovascular Disorders, Healthy, Nervous System Diseases, Spinal Cord Injuries
- Trial name
- NCT00001216
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy Volunteers
Noninvasive Study of Brain Connectivity With EEG and NIRS
Background: Different regions of the brain are activated when a person performs a task. Electroencephalograms (EEGs) and near-infrared spectroscopy (NIRS) are tests that detect changes in the brain.
- Trial name
- NCT01493804
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Diabetes Mellitus
Device Accuracy of Non-invasive Glucose Measurements in Ethnic Skin
This clinical study has been launched to collect spectral raman data paired with validated glucose reference values in private homes of subjects.
- Trial name
- NCT04060693
- Testing
- P0.5
- Where
- United Kingdom
- Sponsor
- RSP Systems A/S
Burns, Shock
An Upgrading of the Resuscitative Patterns by Utilization of the Balanced Crystalloids and Synthetic Colloids and the Non-Invasive Hemodynamic Monitoring During Burn Shock
Fluid Therapy Lithium Dilution Cardiac Output (LIDCO) controlled trial in BURNS (FACT in BURNS) is a prospective randomized multicentric study.
- Trial name
- FACT in BURNS (NCT00914563)
- Testing
- LIDCO Lithium Dilution Cardiac Output, Standard Care
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Urinary Bladder Neoplasms, Carcinoma, Transitional Cell
Toripalimab ± Sequential Intravesical Gemcitabine-Mitomycin C for BCG-Unresponsive/-Intolerant High-Risk NMIBC: Open-Label Randomized Phase 2 Study
This open-label, randomised, multicentre, phase 2 study (OHAI-NMIBC-01) compares toripalimab plus sequential intravesical gemcitabine followed by mitomycin C (GEM→MMC) with toripalimab alone in adults with BCG-unresponsive or…
- Conditions
- Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Carcinoma in Situ of Bladder, Non-Muscle-Invasive Bladder Cancer
- Trial name
- OHAI-NMIBC-01 (NCT07189793)
- Testing
- Toripalimab, Gemcitabine (GEM), Mitomycin C (MMC)
- Where
- China
- Volunteers
- 106 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Non-muscle-invasive Bladder Cancer
Blue Laser -5ala Photodynamic Therapy (PDT) in High-Risk Non-muscle Invasive Bladder Cancer (NMIBC) Patients
This project will conduct a large-sample, multi-center prospective clinical trial to further establish the safety and efficacy of BL-5ALA-PDT in preventing Non-Muscle Invasive Bladder Cancer (NMIBC) recurrence when compared to…
- Trial name
- BL-PDT-RCT (NCT05547516)
- Testing
- Standard infusion chemotherapy, BL - 5 ala PDT
- Where
- China
- Volunteers
- 140 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
High-Risk, Non-Muscle Invasive Bladder Urothelial Carcinoma
Tilelizumab Combined With Nab-Paclitaxel for High-Risk Non-Muscle-Invasive Urothelial Bladder Carcinoma Which is Not Completely Resectable
This is a phase II study to determine the safety and efficacy of tislelizumab when given in combination with nab-paclitaxel as treatment for patients with high-risk non-muscle-invasive bladder cancer (HR NMIBC) which is not…
- Trial name
- NCT04730232
- Testing
- Tislelizumab, Nab-paclitaxel
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Tianjin Medical University Second Hospital
Lung Cancer
Non-Invasive Biomarkers For Early Detection Of Lung Cancers
Recent studies have shown that low-dose chest CT scans can detect lung cancers in high-risk populations (age >50yo, >30 pack-years of tobacco use), and can lower cancer mortality.
- Trial name
- ISRUSAL01 (NCT01580332)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Douglas W. Johnson MD, FACR
Bladder Cancer, Urothelial Carcinoma
Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle Invasive Bladder Cancer (NMIBC)
This study aims to demonstrate that home instillation of UGN-102 is a feasible alternative to instillation in a clinical setting, which might mitigate patient challenges (logistical, expense, and comfort) when receiving treatment…
- Conditions
- Bladder Cancer, Urothelial Carcinoma, Urothelial Carcinoma Bladder
- Trial name
- NCT05136898
- Testing
- UGN-102
- Where
- 5 sites in United States
- Volunteers
- 8 people
- Sponsor
- UroGen Pharma Ltd.
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