Clinical trials: Non-invasive Intracranial Pressure
Intracranial Pathology, Intracranial Hypertension
Clinical Efficacy of a Non-Invasive Measure of Intracranial Pressure
This study is designed to evaluate the accuracy of a non-invasive method phase-contrast magnetic resonance imaging (MR-ICP) for assessing intracranial pressure (Phase 1).
- Trial name
- MR-ICP (NCT03212976)
- Testing
- Phase contrast magnetic resonance imaging
- Where
- 2 sites in United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Miami
Intracranial Hypertension
Non-invasive Intracranial Pressure (ICP) Monitoring in Pediatric Patients
The purpose of this study is to prospectively evaluate the accuracy and safety of non-invasive intracranial pressure (ICP) measurements using the HeadSense-1000 (HS-1000) device compared to the current invasive external…
- Trial name
- NCT02695264
- Testing
- HS-1000 recording
- Where
- United States
- Sponsor
- HeadSense Medical
Intracranial Pressure Increase, Traumatic Brain Injury
Validation of Non-invasive Absolute Intracranial Pressure Monitoring
Primary objective of this study is to assess the accuracy and precision of intracranial pressure (ICP) measurement in patients after traumatic brain injury and subarachnoid hemorrhage when using simultaneous, non-invasive…
- Trial name
- NCT03227354
- Testing
- Vittamed 205
- Volunteers
- 25 people
- Sponsor
- Kienzler Jenny
Brain Injuries
Non-invasive Near-infrared Spectroscopy (NIRS) Versus Invasive Licox Intracranial Pressure
Researchers are trying to assess how accurately and safely NIRS non-invasive monitoring can detect changes in intracranial pressure to determine if this noninvasive device can be used instead of invasive monitoring with Licox in…
- Trial name
- NCT04247321
- Testing
- Licox® Brain Tissue Oxygen Monitoring System, Near-infrared spectroscopy (NIRS)
- Where
- United States
- Sponsor
- Mayo Clinic
Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia
Noninvasive CA Monitoring Validation and Autonomic Modulation in Aneurysmal Subarachnoid Hemorrhage
This is a two-component prospective study of adult aneurysmal subarachnoid hemorrhage (aSAH) patients admitted to the Neurosciences Intensive Care Unit (NSICU) at UT Southwestern Medical Center.
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia, Cerebral Vasospasm, Autonomic Nervous System Diseases
- Trial name
- NCT07577739
- Testing
- Right-Sided Cervical Sympathetic Block at C6, Transcutaneous Auricular Vagal Nerve Stimulation (taVNS)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Texas Southwestern Medical Center
Brain Electrical Impedance;, Non-invasive Intracranial Pressure
Comparison of the Application in Traumatic Brain Edema Between EIT and Non-invasive ICP Monitoring
Brain edema is the main reason for the disability and lethality in traumatic brain injury, which is the most difficult part of emergency rescue. Recently, there is no medical equipment to monitor the early brain edema in clinic.
- Trial name
- EIT (NCT02027857)
- Testing
- EIT monitoring, non-invasive ICP monitoring
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Traumatic Brain Injury
Crainio Non-invasive ICP Monitor for TBI
The clinical investigation aims to advance the Crainio device, designed for non-invasive intracranial pressure (ICP) monitoring.
- Trial name
- NCT06453733
- Testing
- Crainio
- Where
- United Kingdom
- Volunteers
- 54 people
- Sponsor
- Crainio Ltda
Intracranial Pressure Changes
Impact of Low Dose Ketamine Infusion in Septic Patient on Non-invasive Estimators of ICP
Severe sepsis is a major healthcare problem with a reported incidence of 1-2% in all hospitalizations. It is a major cause of death in the intensive care units worldwide and is the second leading cause of death in noncoronary…
- Trial name
- NCT05149586
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
Traumatic Brain Injury (TBI), Subarachnoid Hemorrhage (SAH)
Non-invasive Brain Pressure Monitoring After Trauma or Hemorrhage
Introduction: Increased intracranial pressure (ICP) is considered to be the most important intracranial mechanism causing secondary injury in patients admitted after acute traumatic brain injury (TBI) and intracranial haemorrhage…
- Trial name
- NCT02172703
- Testing
- Non-invasive ICP measurement device
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- Javier Fandino, MD
Cerebral Aneurysms, Intracranial Aneurysms
NOn-inVAsive Blood Pressure Monitoring in Intracranial Aneurysm Embolization
The goal of this clinical trial is to evaluate whether non-invasive continuous blood pressure monitoring (NVBP) using the ClearSight system can safely serve as an alternative to radial arterial catheterization for invasive…
- Conditions
- Cerebral Aneurysms, Intracranial Aneurysms, Coil Embolization, Hemodynamic Instability
- Trial name
- NOVA (NCT07246148)
- Testing
- Non-invasive continuous blood pressure monitoring, Invasive arterial blood pressure monitoring
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Korea University Anam Hospital
Hydrocephalus, Idiopathic Intracranial Hypertension
Comparison of Continuous Non-Invasive and Invasive Intracranial Pressure Measurement
This research is being done to determine the accuracy of two noninvasive methods of measuring the pressure of the cerebrospinal fluid (CSF), also known as intracranial pressure or ICP.
- Conditions
- Hydrocephalus, Idiopathic Intracranial Hypertension, Pseudotumor Cerebri
- Trial name
- NCT01863381
- Testing
- Tympanic membrane displacement (TMD), DPOAE
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- LifeBridge Health
Increase in Intra-abdominal Pressure, Increase in Intracranial Pressure (ICP)
Changes in Cerebral Oxygenation Studies During Laparoscopy Procedure
The motivation results from the fact, that an intra-abdominal pressure is correlated with cerebral perfusion, in a mechanism of reducing venous outflow.
- Conditions
- Increase in Intra-abdominal Pressure, Increase in Intracranial Pressure (ICP), Laparoscopy, Cerebral Perfusion and Oxygenation
- Trial name
- NCT03640741
- Testing
- Laparoscopy
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences
Intracranial Hypertension
Non Invasive Measurement With Trans Cranial Doppler Versus Invasive Measurement in Pediatric Age
An increase of intracranial pressure (ICP) is an important cause of secondary brain damage. The gold standard for measuring ICP is represented by invasive positioning of intracranial ICP devices.
- Trial name
- nICPped (NCT05340062)
- Testing
- bedside sonography
- Where
- 6 sites in Italy
- Volunteers
- 46 people
- Sponsor
- Azienda Ospedaliera di Padova
Traumatic Brain Injury, Intracranial Hypertension
A Non-invasive Intracranial Pressure (nICP) Monitoring System
Researchers have developed a probe that contains infrared light sources that can illuminate the deep brain tissue of the frontal lobe.
- Trial name
- NCT05632302
- Testing
- nICP
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Crainio Ltda
Intracranial Hypertension
A Novel Non-invasive Technique of Cerebral Compliance and Auto-regulation Assessment
Introduction: Intracranial pressure (ICP) monitoring is essential in several medical situations, however, currently there is an invasive technique, costly, not widely available and sometimes contraindicated.
- Trial name
- NCT03144219
- Testing
- Transcranial Doppler (TCD) ultrasound monitoring, Non invasive intracranial compliance monitoring
- Where
- Brazil
- Volunteers
- 133 people
- Sponsor
- University of Sao Paulo
Glioma
Non Invasive Measurements of Intracranial Pressure in Patients With Malignant Glioma
In patients at risk of increased intracranial pressure (ICP), ICP measurements require invasive transducers, usually with insertion of a catheter into the cranium, or through a spinal tap.
- Trial name
- GMaPIC (NCT02520492)
- Testing
- noninvasive method of ICP measurements (Elios)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Jean Perrin
Intracranial Pressure Increase
Non-invasive Absolute Intracranial Pressure Measurement in Patients With Malignant Middle Cerebral Artery Infarction for Determination of Timing to Descompressive Craniectomy.
This is a single centre, observational study with a medical device which has Conformité Européenne (CE) marking. The aim of the study is to demonstrate that patients with malignant middle cerebral artery infarction (M-MCA) show…
- Trial name
- NCT03221959
- Testing
- Medical Device Vittamed 205
- Volunteers
- 48 people
- Sponsor
- Kienzler Jenny
Intracranial Pressure, Intracranial Pressure Changes
Non-invasive Intracranial Pressure Estimation by Measurement of the Occlusion Pressure of the Isolated Periorbital Vein
Elevated intracranial pressure is a common complication of brain injury which means that the pressure within the skull rises above normal levels.
- Trial name
- NCT07222826
- Testing
- CPMX3
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Compremium AG
Intracranial Hypertension, Elevated ICP (Intracranial Pressure)
A Continuous, Non-Invasive, Real-time Method for Estimating and Predicting Intracranial Hypertension
There is statistically significant correlation between invasive measures of intracranial pressure (ICP) and non-invasive, real-time, continuous physiologic waveform data algorithms to predict ICP.
- Trial name
- NCT01448681
- Testing
- No Interventions
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Colorado, Denver
ICP (Intracranial Pressure) Increase, Optic Nerve Sheath Diameter
Optic Nerve Sheath Diameter: A Non-Invasive Indicator of Intracranial Pressure in the Intensive Care Unit Monitoring
Determination of high intracranial pressure (ICP) is necessary for the treatment of patients with raised ICP to improve long-term neurological outcomes.
- Conditions
- ICP (Intracranial Pressure) Increase, Optic Nerve Sheath Diameter, Intracranial Hypertension
- Trial name
- NCT06367868
- Testing
- After 5 ml CSF Drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul University - Cerrahpasa