Clinical trials: Non-invasive Ventilation
Healthy
Effects of Non-invasive Ventilation on Function Diaphragmatic and Caval Distension
Introduction: Understanding how the applicability of non-invasive ventilation can directly affect the anatomy and diaphragmatic function, as well as the opening diameter of the inferior vena cava in healthy individuals is…
- Trial name
- NCT06384027
- Testing
- Non-invasive ventilation
- Where
- Brazil
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Non-invasive Ventilation, High-frequency Ventilation
Evaluation of Prolonged Apnea Supported by High Frequency Non-invasive Ventilation.
The purpose of the study is to assess the efficacy of high-frequency non-invasive ventilation on apnea duration, carbon dioxide clearance and oxygen delivery in healthy subjets and patients with lung disease.
- Conditions
- Non-invasive Ventilation, High-frequency Ventilation, Healthy Volunteer, Lung Diseases
- Trial name
- ANIV (NCT02712190)
- Testing
- High-frequency non-invasive ventilation
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Chest Trauma
Sedation for Non-invasive Ventilation in Blunt Chest Trauma
Effectiveness of sedation using dexmedetomidine and ketamine to facilitate non-invasive ventilation sessions which improve overall outcome after blunt chest trauma
- Trial name
- NCT05175781
- Testing
- Dexmedetomidine Hydrochloride, Ketamine Hydrochloride
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Aswan University Hospital
Heart Failure
Non-invasive Ventilation in Patients With Cardiac Heart Failure
Patients with heart failure (HF) have a reduced exercise tolerance as the main result of the disease. This exercise intolerance is due to heart conditions, but also to dysfunction of the respiratory and peripheral muscles.
- Trial name
- NCT05433610
- Testing
- Non-invasive Ventilation
- Where
- Argentina
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Gran Rosario
Upper Airway Obstruction
Identification of Airway Structures Necessary for Airway Access Via the Skin
Literature shows that anaesthetists have a low success-rate when trying to access the airway percutaneously in case of failed ventilation and intubation.
- Trial name
- NCT02613429
- Testing
- identification of the airway by from the cranial end, identification of the airway from the distal end
- Where
- 2 sites in Denmark
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Healthy Volunteers
The Effect of Home and Hospital Mask Designs on Respiratory Variables in Healthy Volunteers
The goal of this randomized cross-over study is to investigate whether the design of non-invasive ventilation (NIV) mask impacts respiratory variables in healthy volunteers on NIV therapy.
- Trial name
- NCT07463716
- Testing
- Non-invasive ventilation (NIV)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fisher and Paykel Healthcare
Quality of Life
Consequences of Respiratory Devices on Caregivers (CAP2)
The promoter of the study will conduct a monocentric cohort study that aim to evaluate the consequences of home respiratory devices on patient caregivers' quality of life.
- Trial name
- CAP2 (NCT04632836)
- Testing
- quality of life questionnaires
- Where
- France
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Asten Sante
Respiration, Artificial, Critical Illness
Medical Gas Humidification During Noninvasive Mechanical Ventilation
In this study, the investigators aimed to study the role of medical gas humidification during noninvasive mechanical ventilation.
- Trial name
- NCT00124345
- Testing
- MR730
- Where
- Italy
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital
Cardiogenic Pulmonary Edema
Helmet CPAP Versus HFNC in Acute Cardiogenic Pulmonary Edema
This study objectively held to compare the physiological outcomes in the non-invasive (NIV) treatment of Acute Cardiogenic Pulmonary Oedema (ACPE) patients in the Emergency Department (ED) delivered by Helmet CPAP (hCPAP) and…
- Trial name
- HCPAPvsHFNC (NCT04005092)
- Testing
- hCPAP versus HFNC
- Where
- Malaysia
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Hospital Raja Permaisuri Bainun
Chronic Obstructive Pulmonary Disease, Pulmonary Rehabilitation
Effects of Nocturnal Non-invasive Ventilation on Energy Expenditure in Patients With Severe Chronic Obstructive Pulmonary Disease
It has been shown, that in patients with very severe chronic obstructive pulmonary disease (COPD) the additional use of non-invasive ventilation during pulmonary rehabilitation (PR) may enhance the benefits of PR.
- Conditions
- Chronic Obstructive Pulmonary Disease, Pulmonary Rehabilitation, Non-invasive Ventilation, Energy Expenditure
- Trial name
- NCT01961245
- Testing
- nocturnal non-invasive ventilation
- Where
- Germany
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Schön Klinik Berchtesgadener Land
Blood Oxygen Desaturations, Sleep-Disordered Breathing
Assessment of the Accuracy of the Non-invasive Wireless Armband Gabi Baby Band for Continuous Vital Parameters Monitoring in Infants and Young Children
During a polysomnography test (PSG) previously prescribed by a physician, the patient also wears the Gaby Baby Band (GBB) during an entire night of sleep.
- Trial name
- WAGSC1 (NCT04886583)
- Testing
- Gabi Baby Band
- Where
- 3 sites in Belgium
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Gabi SmartCare
Chronic Obstructive Pulmonary Disease Exacerbation
Evaluation of Oxygen Delivery Methods in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
To examine the effects of oxygen therapy methods applied as indicated in COPD acute exacerbations on blood gas results and spirometric measurements.
- Trial name
- NCT06561464
- Testing
- EzPAP®, Non-invasive mechanical ventilation (NIMV)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Pediatric Sleep Apnea, Obstructive Sleep Apnea
Photobiomodulation for Pediatric Hypertrophic Tonsils
Pediatric obstructive sleep apnea is a medical condition where a child has great difficulty with breathing, or stops breathing all together, while asleep.
- Conditions
- Pediatric Sleep Apnea, Obstructive Sleep Apnea, Tonsils Hypertrophy
- Trial name
- NCT05459935
- Testing
- PBM Tonsil Arm
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Elective Procedures Requiring Mechanical Ventilation
Evaluation of Novel Cardio-Pulmonary Physiological Monitor, the VQm PHM™, for Acute Care Medicine
This is a prospective, observational study to assess agreement of pulmonary health parameters measured by a new non-invasive physiologic monitor, the VQm pulmonary health monitor (PHM)™ with clinical gold standards.
- Trial name
- NCT04730063
- Testing
- VQm PHM™
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rostrum Medical Innovations Inc.
Kyphoplasty, Prone Position
TCI Versus Manual TIVA for Sedation During Prone Kyphoplasty: Effects on Respiration, Recovery, and EEG
This single-center, prospective, observational study compares target-controlled infusion (TCI) versus manually administered total intravenous anesthesia (TIVA) for sedation in patients undergoing kyphoplasty in the prone…
- Conditions
- Kyphoplasty, Prone Position, Target Controlled Infusion of Propofol, End Tidal Carbon Dioxide
- Trial name
- NCT07745348
- Testing
- Target controlled infusion of propofol, non invasive ETCO2 monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Preterm, Ventilator Lung; Newborn
Evaluation of Nasal Non Invasive Ventilation in Management of Neonates With Respiratory Distress Using Lung Ultrasound
This study aims to evaluate the effect of non-invasive ventilation (nIPPV) , (nCPAP), and nasal high flow cannula (NHFC) as a primary mode of ventilation in preterm neonates <37 gestational week with moderate to severe RD using…
- Trial name
- NCT06550219
- Testing
- Nasal humidified heated high flow cannula (NHHHC), Nasal intermittent positive pressure ventilation (NIPPV), Nasal continuous positive airway pressure NCPAP
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Noninvasive Ventilation, Patient Positioning
Distribution of Pulmonary Ventilation in Lateral Decubitus of Healthy Adults Under Non-Invasive Mechanical Ventilation
The aim was to investigate via impedance tomography apparatus the distribution of pulmonary ventilation at a lateral position at different Continuous Positive Airway Pressure levels (0, 5, 10 cm Η2Ο) in healthy subjects.
- Trial name
- NCT06489509
- Testing
- Positive End Expiratory Pressure 5 H2O, Positive End Expiratory Pressure 10 H2O
- Where
- 2 sites in Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Attikon Hospital
Fluid Responsiveness, Hemodynamics
Hemodynamic Evaluation and Fluid Response Observation Through Respiratory Maneuvers
This study evaluates whether respiratory maneuvers can induce measurable hemodynamic changes and whether these changes may be used to assess fluid responsiveness in healthy volunteers.
- Trial name
- HERO (NCT07840040)
- Testing
- Respiratory Maneuvers and Fluid Responsiveness Assessment Protocol
- Where
- Czechia
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University Hospital Pilsen
Neoplasms
Chest Imaging of Lung Nodule(s) Under High-frequency Non-invasive Ventilation (HF-NIV)
Imaging of chest disorders is mainly achieved by using computed tomography. This is especially the case for detection, morphologic assessment and followup of pulmonary nodules.
- Trial name
- NCT03553368
- Testing
- HF-NIV-MR, HF-NIV-PET, MR
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Obstructive Sleep Apnea (OSA)
Fractional Exhaled Nitric Oxide as Possible Non - Invasive Biomarker to Assess Obstructive Sleep Apnea Severity
Aim of work 1. Primary aim: Asses correlation between FeNO level, OSA severity 2. Secondary aim: Clarifying FeNO's role as a biomarker to assess airway inflammation, Cut off value prediction to moderate and severe OSA and its…
- Trial name
- NCT07606898
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tanta University