Clinical trials: Non-ischemic Cardiomyopathy
Acute Heart Failure, NSTEMI - Non-ST Segment Elevation MI
Metabolomics and Microbiomics in Cardiovascular Diseases
"MEtabolomics and MicrObiomics in caRdIovAscular diseases Mannheim (MEMORIAM) " is a single-center, prospective and observational study investigating to identify disease-specific metabolic, respectively microbiomic, patterns of…
- Conditions
- Acute Heart Failure, NSTEMI - Non-ST Segment Elevation MI, STEMI - ST Elevation Myocardial Infarction, Myocardial Infarction, Acute
- Trial name
- MEMORIA (NCT04146701)
- Testing
- Blood draw
- Where
- Germany
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Cardiovascular Diseases, Heart Failure
Longitudinal Validation of CIRC Technologies
Cardiovascular disease is the leading cause of death worldwide. Advanced cardiovascular imaging using Magnetic Resonance Imaging (MRI) has proven to be effective in providing gold standard myocardial tissue characterization.
- Conditions
- Cardiovascular Diseases, Heart Failure, Ischemic Heart Disease, Non-ischemic Cardiomyopathy
- Trial name
- NCT07081711
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Coronary Artery Disease, Heart Failure
Stress Echo 2020 - The International Stress Echo Study
Background: Stress echocardiography (SE) has an established role in evidence-based guidelines, but recently the breadth and variety of applications has extended well beyond coronary artery disease (CAD).
- Conditions
- Coronary Artery Disease, Heart Failure, Hypertrophic Cardiomyopathy, Aortic Valve Disease
- Trial name
- SE2020 (NCT03049995)
- Testing
- Left ventricular contractile reserve SE, B-lines SE, Left ventricular outflow tract gradient SE
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fatebenefratelli Hospital
Cardiovascular Diseases, Heart Failure
Development of CIRC Technologies
Cardiovascular disease is the leading cause of death worldwide. Advanced cardiovascular imaging using Magnetic Resonance Imaging (MRI) has proven to be effective in providing gold standard myocardial tissue characterization.
- Conditions
- Cardiovascular Diseases, Heart Failure, Ischemic Heart Disease, Non-ischemic Cardiomyopathy
- Trial name
- CIRC (NCT05654272)
- Testing
- MRI
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Cardiomyopathies, Insulin Resistance
Early MRI Detection of Myocardial Deterioration as a Preventive, Disease Staging, and Prognostic Biomarker in Insulin Resistance
The purpose of this study is to evaluate the relationship between insulin resistance (IR) and myocardial tissue abnormalities. The study will focus on a patient population, South Asians, with a high prevalence of IR.
- Conditions
- Cardiomyopathies, Insulin Resistance, Non-ischemic Cardiomyopathy, Cardiac Fibrosis
- Trial name
- NCT03509441
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Stanford University
Hypertrophic Cardiomyopathy, Acute Coronary Syndrome
Study to Develop a Non-invasive Marker for Monitoring Myocardial Fibrosis
The objective is to determine whether 99Technetium-NC100692 uptake in patients with ACS (MI) can serve as a marker for scar formation as detected by contrast-enhanced MRI during the process of myocardial remodelling after the…
- Trial name
- SCAR (NCT01230918)
- Testing
- 99mTc-NC100692
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Ventricular Tachycardia
Surpoint Algorithm for Improved Guidance of Ablation for Ventricular Tachycardia
Vistag SurPoint is a proprietary module that generates a numerical tag index which can be used as multiparametric lesion quality marker to guide ablation in the clinical setting for ablation of atrial arrhythmias.
- Trial name
- SURFIRE-VT (NCT05618717)
- Testing
- Radiofrequency Ablation
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Mitral Valve Insufficiency, Dilated Cardiomyopathy
Prospective Study Looking at Quality of Life Measures in Non-ischaemic Cardiomyopathy After Mitral Valve Repair
Chronic severe mitral regurgitation can lead to symptoms and left ventricular dysfunction. The purpose of this study is to prospectively follow patients with non-ischaemic cardiomyopathy who are eligible for mitral valve repair…
- Conditions
- Mitral Valve Insufficiency, Dilated Cardiomyopathy, Congestive Heart Failure
- Trial name
- NCT00483236
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre