Clinical trials: Non-smoker
Lung Cancer, Tobacco Use Disorder
Standard Medical Care or Urgent Chest X-ray in Diagnosing Lung Cancer in Smokers With Chest Symptoms Who Are Older Than 60 Years
RATIONALE: Diagnostic procedures, such as an urgent chest x-ray, may help in planning cancer treatment. It is not yet known whether standard medical care is more effective than an urgent x-ray in diagnosing lung cancer in smokers…
- Trial name
- NCT01344005
- Testing
- caregiver-related intervention or procedure, questionnaire administration, quality-of-life assessment
- Volunteers
- 386 people
- Sponsor
- Wales Cancer Trials Unit
Lung Adenocarcinoma, Lung Adenosquamous Carcinoma
Erlotinib Hydrochloride With or Without Carboplatin and Paclitaxel in Treating Patients With Stage III-IV Non-small Cell Lung Cancer
This randomized phase II trial studies how well erlotinib hydrochloride with or without carboplatin and paclitaxel works in treating patients with stage III-IV non-small cell lung cancer.
- Conditions
- Lung Adenocarcinoma, Lung Adenosquamous Carcinoma, Malignant Pericardial Effusion, Malignant Pleural Effusion
- Trial name
- NCT00126581
- Testing
- Carboplatin, Erlotinib, Erlotinib Hydrochloride
- Where
- 96 sites in United States
- Volunteers
- 188 people
- Sponsor
- National Cancer Institute (NCI)
Nicotine Dependence
Imaging Extrastriatal Dopamine Release in Tobacco Smokers and Nonsmokers
The goal is to examine sex differences in amphetamine-induced dopamine release in tobacco smokers and nonsmokers.
- Trial name
- NCT02348385
- Testing
- Amphetamine
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Yale University
Smokers, Vaping
Persistence of Oral DNA Adducts in Smokers and Vapers
This study aims to better understand what damage caused to oral cells from smoking and vaping might be important in the formation of oral cancers.
- Conditions
- Smokers, Vaping, Healthy Volunteers
- Trial name
- NCT06983392
- Testing
- Abstain from smoking/vaping
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy, Smokers
Effect of Whole Body Periodic Acceleration on Airway Endothelial Function
In the present proposal the investigators wish to assess the effect of a single session with the device known as Exer-Rest® which applies Whole Body Periodic Acceleration (WBPA) on baseline airway blood flow (Qaw) and in Qaw…
- Conditions
- Healthy, Smokers, Asthma
- Trial name
- NCT01213706
- Testing
- Whole Body Periodic Acceleration (WBPA)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Miami
Periodontitis, Adult
Non-surgical Periodontal Treatment in Smokers on SIRT-1, NLRP3 Inflammasome and LncRNAs
The goal of this observational is to analyze the relationship between levels of interleukin-18 (IL-18), interleukin (IL-1β), Tumor Necrosis Factor-alpha (TNF-α), interleukin-10 (IL-10), transforming growth factor beta (TGF-β)…
- Trial name
- NCT06351722
- Testing
- Before non-surgical periodontal treatment, non-surgical periodontal treatment, 3rd month after non-surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
PASSIVE SMOKING ,, RESPIRATORY SYSTEM MECHANICS,
Effects Of Passive Smoking On The Respiratory System Mechanics Of Healthy Non-Smokers In Different Body Positions
The study will examine changes in the respiratory system mechanics and in respiratory physiology after exposure of subjects to passive smoking.
- Trial name
- NCT02171871
- Testing
- exposed to a smoking environment
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hellenic Anticancer Society
Cigarette Smoker, Current Every Day Smoker
Tailored Smoking Cessation Intervention in Promoting Sexual and Gender Minority Smokers to Quit Smoking
This trial studies how well tailored smoking cessation intervention works in promoting sexual and gender minority smokers to quit smoking.
- Trial name
- NCT03669120
- Testing
- Informational Intervention, Telephone-Based Intervention
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Health Risk Behaviors, Non Communicable Diseases
Compare Smokers' Appraisal of Proposed Plain Packs and Existing Cigarette Packs
2 Objectives 1. To explore the noticeability of pictorial health warnings and perceptions of attractiveness and harmfulness towards plain cigarette packets and existing cigarette packets with 85% pictorial warnings in current…
- Trial name
- NCT05907226
- Where
- Hong Kong
- Volunteers
- 1,283 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Cholecystectomy, Laparoscopic
Arterial Blood Gas Analysis in Laparoscopic Cholecystectomy
The investigator found out that as such the base line carbon dioxide (CO2) level is higher in smokers as compared to non-smokers even before creation of pneumoperitoneum, which is due to the compromised lung function following…
- Trial name
- ABG (NCT03133494)
- Testing
- ABG analysis
- Volunteers
- 60 people
- Sponsor
- Banaras Hindu University
Household Air Polution, Cardiovascular Diseases
GEOHealth Hub: Household Air Pollution and Cardio-pulmonary and Immune Function Outcomes
Background: The increasing effect of environmental, occupational and climate change poses serious global threat for public health.
- Conditions
- Household Air Polution, Cardiovascular Diseases, Lung Diseases, Immune Dysfunction
- Trial name
- NCT02824237
- Testing
- Improved cook stove
- Where
- Bangladesh
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Asthma, COPD
Leukocyte Function in Asthma and COPD
The aim of this study is to examine the inflammatory mechanisms involved in the pathogenesis of inflammatory lung disease, in particular to compare the inflammatory profile seen in asthma and COPD.
- Conditions
- Asthma, COPD, Emphysema, Chronic Bronchitis
- Trial name
- NCT00147069
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Periodontitis, Adult
GCF miRNA-223 , -214 Levels in Smokers and Nonsmokers Periodontitis Patients
Objective: Periodontitis is a multifactorial disease that affects a wide range of populations. However, its pathogenesis remains unclear. miRNAs are now considered potential diagnostic markers for many inflammatory diseases.
- Trial name
- NCT06064799
- Testing
- miRNA-223 & -214 detection
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Lung Disease, Chronic Obstructive Pulmonary Disease (COPD)
Lung Disease Collection (Qatar): Evaluation of the Lungs of Individuals With Lung Disease
The purpose of this protocol is to obtain biologic samples from the blood and lungs from patients with lung diseases in order to study the causes and indications of these disorders, learn how these lung disease manifest and…
- Conditions
- Lung Disease, Chronic Obstructive Pulmonary Disease (COPD), Asthma
- Trial name
- Q-LD (NCT00504738)
- Where
- Qatar
- Volunteers
- 75 people
- Sponsor
- Weill Medical College of Cornell University
Periodontal Diseases, Tooth Loss
Effect of Periodontal Maintenance Therapy on Tooth Loss in Regular and Irregular Compliant Smokers and Non-Smokers: A Cohort Retrospective Analysis With a Follow-up Up to 40 Years
Periodontal diseases are infections cause by dental plaque (Socransky, 1970). Risk factors are present which modify the course of disease progression.
- Conditions
- Periodontal Diseases, Tooth Loss, Compliance, Smoking
- Trial name
- NCT04938089
- Testing
- Maintenance
- Where
- Lebanon
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Bladder Cancer, Cervical Cancer
Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking
RATIONALE: A stop-smoking plan that includes health education counseling and bupropion may help African-American smokers stop smoking.
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00666978
- Testing
- smoking cessation intervention, bupropion hydrochloride, gene expression analysis
- Where
- 2 sites in United States
- Volunteers
- 540 people
- Sponsor
- Lisa Sanderson Cox, PhD
Lung Cancer, Precancerous Condition
ACAPHA in Preventing Lung Cancer in Former Smokers With Bronchial Intraepithelial Neoplasia
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. The use of ACAPHA, a combination of six herbs, may prevent lung cancer from forming in former smokers with bronchial intraepithelial neoplasia.
- Trial name
- NCT00522197
- Testing
- multi-herbal agent ACAPHA, Sugar Pill
- Volunteers
- 90 people
- Sponsor
- British Columbia Cancer Agency
Cigarette Smoking, Addiction Nicotine
Investigation of Cigarette Cravings in Smokers
Interventions to disrupt memory reconsolidation have held promise for the treatment of stress- and anxiety-related disorders. In the present study, the investigators will examine whether an intervention based on these principles…
- Conditions
- Cigarette Smoking, Addiction Nicotine, Tobacco Use
- Trial name
- NCT04843969
- Testing
- Stress induction, Control stress exposure, Cue induction
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- Marco Leyton
Heavy Smoker or Non-smoker
Antioxidant Effect of Aged Garlic Extract
This is a randomized, double-blind, placebo controlled, crossover study to determine the antioxidant effect of aged garlic extract. This study will also compare the oxidative status in heavy smokers with that in non-smokers.
- Trial name
- NCT02019368
- Testing
- Aged garlic extract
- Where
- Japan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
Tobacco Use
Oral Nicotine Pouch Marketing Features Influence on Perceptions
This study tests the effects of three oral nicotine marketing features on product perceptions.
- Trial name
- NCT06605924
- Testing
- Tobacco-free, Discrete, Convenient
- Where
- United States
- Volunteers
- 5,133 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health