Clinical trials: Non-smokers
Periodontitis, Cigarette Smoking
The Impact of Cigarette Smoking on Periodontal Therapy
Periodontitis patients, 40 cigarette smokers and 40 non-smokers (defined by cotinine measures in serum), were recruited to this double arm prospective cohort study.
- Trial name
- NCT05120206
- Testing
- Non-surgical periodontal therapy: motivation and instruction in oral hygiene, debridement using handinstrumentation (Hu-Firedy,Chicago, IL, USA;and American Eagle Instruments,Missoula, MT,USA).
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Respiratory Disorders
A Study to Assess Immunity to Specific Microbial Antigens in Healthy Smokers and Non-smokers and in Subjects With Stable COPD
The present study aims to assess the natural immunity to specific microbial antigens in healthy subjects and in subjects with stable COPD aged between 45-75 years.
- Trial name
- NCT01516437
- Testing
- Blood collection, Swab collection, Sputum collection
- Where
- 3 sites in Belgium
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pollution; Exposure, Smoke Inhalation
Controlled Exposure of Healthy Nonsmokers to Secondhand and Thirdhand Cigarette Smoke
This study compares the health effects of dermal and inhalational exposure to thirdhand cigarette smoke to those of inhalational exposure to secondhand cigarette smoke in healthy, adult nonsmokers.
- Conditions
- Pollution; Exposure, Smoke Inhalation, Exposure to Pollution
- Trial name
- THS04 (NCT04013256)
- Testing
- Cigarette Smoke
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking Cessation
Safety and Pharmacodynamics of SEL-068 Vaccine in Smokers and Non-Smokers
The purpose of this study is to evaluate the safety and pharmacodynamics of SEL-068. Increasing subcutaneous doses of SEL-068 will be administered to healthy non-smoker and smoker volunteers.
- Trial name
- NCT01478893
- Testing
- SEL-068, Saline
- Where
- Belgium
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Selecta Biosciences, Inc.
Tobacco Use Disorder
Varenicline-Aided Cigarette Reduction in Smokers Not Ready to Quit
The investigators will randomize smokers to receive 1) Varenicline + smoking cessation/reduction counseling or 2) Placebo pill + smoking cessation/reduction counseling.
- Trial name
- NCT01308736
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Lung Cancer
Lung Cancer Biomarkers and Screening
RATIONALE: Screening tests that use biomarkers may help doctors find tumor cells early and plan effective treatment for lung cancer. PURPOSE: This clinical trial is studying biomarkers in screening participants for lung cancer.
- Trial name
- NYULCBC (NCT00301119)
- Where
- United States
- Volunteers
- 3,606 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Periodontal Diseases
Comparison of Salivary Biormarkers Levels With Periodontal Clinical Parameters in Smokers and Non-Smokers With Different Periodontal Diseases
To better understand the pathogenesis of chronic inflammatory diseases, the levels of various cytokines are commonly analyzed in tissues and biological fluids collected from the body.
- Trial name
- NCT06459037
- Testing
- Saliva obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Healthy Subjects
A Study To Investigate The Metabolism Of GW876008 In Smokers Compared To Non-Smokers.
This study will investigate the effect of smoking on the metabolism of a single oral dose of GW876008.
- Trial name
- NCT00429728
- Testing
- GW876008
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Smoking
The Effects of Smoking Withdrawal On Resting State Functional Connectivity
The purpose of this study is to see how the brain differs between smoking regularly and after not smoking for 24 hours. The investigators will be using an MRI machine to get the information from adult smokers and non-smokers…
- Trial name
- SmokeAtt04 (NCT01632384)
- Testing
- Abstain from smoking for 24 hours
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Smoking ( Cigarette), Cardiovascular Disease
SMOKING AND PRESENCE OF FRANK'S SIGN
In this study, the effect of cigarette smoking-one of the major risk factors for cardiovascular diseases-on the development of Frank's sign (DELC) was investigated.
- Trial name
- NCT07427745
- Testing
- To obtain bilateral ear photographs, To take a medical history
- Where
- Turkey (Türkiye)
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Samsun University
Lung Cancer
LDCT Screening in Non-smokers in Taiwan
This study utilizes the low dose computed tomography(LDCT) to detect the occurrence of early lung cancer among non-smokers in Taiwan.
- Trial name
- NCT02611570
- Testing
- LDCT
- Where
- 17 sites in Taiwan
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Academia Sinica, Taiwan
Dentin Sensitivity
Longevity and Effectiveness of Bleaching in Healthy and Smokers Patients
The main objective of this study is to evaluate the effectiveness and longevity of color and Tooth sensitivity of patients undergoing home whitening peroxide 10% carbamide ( Whiteness Perfect , FGM , Joinville , Santa Catarina …
- Trial name
- BLESMOK (NCT02017873)
- Testing
- Peroxide Carbamide 10% - Dental bleaching treatment
- Where
- 2 sites in Brazil, Chile
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Chile
Smoking, Non-smoking
Smoking Research Study
The purpose of this study is to develop a fit-for-purpose biochemical verification tool that can be used to detect concomitant use of a few (less than 5) conventional cigarettes.
- Trial name
- NCT01465880
- Testing
- Part A
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Smoking Cessation
Strategies to Promote Cessation in Smokers Who Are Not Ready To Quit
To our knowledge, no study has evaluated the independent effects of motivational interviewing and rate reduction, individually versus in combination, for motivating smokers who are not ready to quit (SNRTQ) to increase both quit…
- Trial name
- PACE (NCT02905656)
- Testing
- Brief Advice, Motivational Interviewing, Rate Reduction
- Where
- United States
- Volunteers
- 903 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Healthy
A Phase 1 Study To Investigate The Pharmacokinetics, Safety And Tolerability Of CP-601,927 In Healthy Japanese Subjects
This Phase 1 study is the first clinical trial to be conducted in Japanese subjects. The pharmacokinetics, safety and tolerability of single and multiple doses of CP-601,927 will be evaluated in Japanese, healthy, non-smoking…
- Trial name
- NCT01396135
- Testing
- CP-601,927
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pfizer