Clinical trials: Non-surgical Periodontal Therapy
Periodontitis
Effect of Probiotics as Supplement to Non-surgical Periodontal Treatment
The present study is a double-blinded randomized clinical trial with a duration of 12 weeks.
- Trial name
- NCT05518747
- Testing
- Probiotic
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Copenhagen
Endodontically Treated Teeth, Calcium Hydroxide
Multiple-Visit RCT in Teeth With SAP: Interappointment Dressing or Not?
The aim of the study is to evaluate the effectiveness of calcium hydroxide as an intracanal medicament in the clinical and radiographic healing of periapical tissues in teeth diagnosed with symptomatic apical periodontitis.
- Trial name
- RCTCa(OH)2 (NCT06447519)
- Testing
- Ca(OH)2 as intracanal medicament
- Where
- Greece
- Volunteers
- 110 people
- Sponsor
- Aristotle University Of Thessaloniki
Periodontitis
Low Laser Therapy and Hyaluronic Acid as an Adjunct to Non-surgical Periodontal Therapy
Periodontal disease is an oral disease characterized by microbially associated, host-mediated inflammation of the periodontium. In the treatment of periodontal disease, conventional periodontal therapy includes both surgical and…
- Trial name
- NCT05907161
- Testing
- SRP+LASER (Dentsply Sirona - SIROLaser Blue), SRP+HA, SRP
- Where
- Slovenia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Periodontitis (Stage 3)
Hydrolyzed Collagen As A Host Modulation Agent in Non-Surgical Periodontal Treatment
This study was planned on the basis of the hypothesis that 'food supplements containing collagen will support the clinical effectiveness of non-surgical periodontal therapy'.
- Trial name
- NCT07683741
- Testing
- Collagen hydrolyzed peptides
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hatice Yemenoglu
Stress, Psychological, Periodontal Diseases
Effect of Stress on Periodontal Therapy (NPT)
Aim of this study: is to evaluate the influence of stress level on the response of non surgical periodontal therapy in patients affected by severe periodontitis divided into "Medium/High stress level" or "Low stress level" based…
- Conditions
- Stress, Psychological, Periodontal Diseases, Periodontitis, Non Surgical Periodontal Therapy
- Trial name
- NCT04739475
- Testing
- Non Surgical Periodontal Therapy
- Where
- Italy
- Volunteers
- 89 people
- Sponsor
- University of Turin, Italy
Ozone-therapy (O3), Periodontitis
Ozone-therapy in Non-surgical Periodontal Therapy
Non-surgical periodontal therapy is a widely adopted procedure for the treatment of periodontitis, particularly in its moderate to severe stages.
- Conditions
- Ozone-therapy (O3), Periodontitis, Antimicrobial Ozone Therapy
- Trial name
- PD-OZONE (NCT07202312)
- Testing
- Ozone-therapy after non-surgical therapy
- Where
- Italy
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Periodontal Therapy, miRNA-223
The Effects of Smoking on miRNA-223 Before-After Non-Surgical Periodontal Therapy
Periodontal diseases are one of the most common inflammatory diseases. Periodontal disease results from a complex interplay between the subgingival biofilm and the host immune-inflammatory events that develop in the gingival and…
- Conditions
- Periodontal Therapy, miRNA-223, Periodontitis, Biomarker
- Trial name
- NCT05372965
- Testing
- experimental-periodontitis-mirna-223-gingival tissue-saliva samples, control-clinical healthy mirna-223-gingival tissue-saliva samples
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Biruni University
Periodontal Bone Loss, Periodontal Pocket
Treatment of Intraosseous Periodontal Defects With Amelogenins
The aim of the present investigation will be evaluate the healing of periodontal intraosseous defects following Minimally Invasive Non Surgical Debridement (MINSD) and application of amelogenins, compared to MINSD alone.
- Trial name
- NCT05315804
- Testing
- MINSD and amelogenins, MINSD
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Federico II University
Periodontal Diseases, Periodontitis
miRNAs in Periodontal Disease
It has been stated that microRNA (miRNA) play an important role in development, homeostasis and immune functions, and abnormal miRNA expression may cause faster disease progression.
- Conditions
- Periodontal Diseases, Periodontitis, Gingivitis
- Trial name
- NCT05046678
- Testing
- Control, Smokers with periodontally healthy, Non-smokers with gingivitis
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Peri-implant Mucositis
Chlorhexidine Gel and Peribioma Periogel Use in Peri-implant Mucositis Sites: a Split-mouth Randomized Clinical Trial.
The aim of this study is to evaluate the efficacy of non-surgical periodontal therapy with supportive home oral care for the treatment of peri-implant mucositis.
- Trial name
- NCT04899986
- Testing
- Chlorhexidine and Biorepair gel and toothpaste application, Standard oral hygiene
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Pavia