Clinical trials: Non-visual Effects of Light
Non-visual Photoreception
Investigating the Effects of Evening Light Exposure on Melatonin Suppression, Alertness and Nocturnal Sleep
The timing and quality of sleep is governed by environmental and physiologic factors. Environmental factors, especially ambient lighting can impact the circadian system and alter the timing and structure of sleep.
- Trial name
- NCT01586039
- Testing
- Visible light
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Sleep Disorders, Neurological Pathologies
Photomotor Reflex to Evaluate the Role of the Non-visual Effects of Light in Neurological, Psychiatric and Ophthalmological Pathologies
The light has visual and non-visual effects on organism and can act on the behavior, the mood, the cognition and the sleep. These effects are mediated by "classical" retina photoreceptors which allow vision (rods, cones) but also…
- Conditions
- Sleep Disorders, Neurological Pathologies, Psychiatric Pathologies, Ophthalmological Pathologies
- Trial name
- NCT03811964
- Testing
- Specific light exposures
- Where
- France
- Volunteers
- 726 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Non-visual Effects of Light, Chronic Variable Sleep Deficiency
Sleep, Light, Circadian, Central Oxidative Stress
Irregular sleep timing and sleep deficiency are pervasive in society despite evidence that sleep deficiency impairs cognition and is linked to neurodegenerative disease.
- Trial name
- NCT07471126
- Testing
- Chronic Variable Sleep Deficiency, Sleep- and Circadian-Informed Lighting, Dim Light
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Healthy, Bipolar
Examining Lithium's Mechanism in Bipolar Disorder
The primary objective of the current study is to examine the acute effect of lithium on the visual and non-visual responses to light in a sample of healthy participants.
- Trial name
- HELIOS-BD 2 (NCT07750925)
- Testing
- Lithium carbonate (Priadel), Controlled light exposure
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Non-visual Effects of Light
Effect of Lighting Supplementation on Daytime Cognition
The aim of the study is to examine the efficacy of supplementing sub-optimal ambient room lighting with a task lamp on working memory and procedural learning.
- Trial name
- NCT04745312
- Testing
- Visible light
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Myopia
Effects of Blue of Glasses VS Standard Lenses on Contrast Sensitivity & Visual Fatigue in Myopic & Non-Myopic Adults
This study investigates the effects of blue light-blocking glasses compared to standard lenses on contrast sensitivity and visual fatigue in myopic and non-myopic adults.
- Trial name
- NCT06739525
- Testing
- Blue Light-Blocking Glasses (Intervention Group), Standard Lenses (Control Group)
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Superior University