Clinical trials: Nonadherence, Patient
Medication Adherence, Medication Nonadherence
Identifying Reasons for Non-adherence in Patients With Multi-morbidity
The study will be carried out during pharmacist-conducted medication reconciliation. The pharmacist will ask how the patient has been taking the prescribed medicines and whether any over-the-counter medicines and food supplements…
- Conditions
- Medication Adherence, Medication Nonadherence, Chronic Disease
- Trial name
- NCT05167578
- Testing
- Medication reconciliation
- Where
- Finland
- Volunteers
- 250 people
- Sponsor
- Helsinki University Central Hospital
Patient Non-Compliance, Schizophrenia and Related Disorders
Study on Psychoeducation Enhancing Results of Adherence in Schizophrenia
Background: Psychosis in the spectrum of schizophrenia (PSS) are severe mental disorders, with a high impact on disability and participation. Poor adherence to pharmacotherapy negatively impacts on the course and outcome of PSS.
- Trial name
- SPERA-S (NCT01433094)
- Testing
- Falloon et al. Psychoeducation Program, Generic Treatment
- Where
- 8 sites in Italy
- Volunteers
- 112 people
- Sponsor
- University of Cagliari
CHF - Congestive Heart Failure
Digital Outreach for Heart Failure Adherence
The goal of the ADHERE-HF study is to evaluate whether care-embedded, operationally delivered digital outreach improves medication refill, adherence, and clinical outcomes among adults with heart failure who are overdue for a…
- Trial name
- ADHERE-HF (NCT07831538)
- Testing
- Digital Outreach
- Where
- United States
- Volunteers
- 13,714 people
- Sponsor
- Kaiser Permanente
Adherence, Medication, Nonadherence, Medication
Interventions to Improve Specialty Medication Adherence
Patients deemed nonadherent to their specialty medications will be randomized to receive 8 months of patient-tailored adherence interventions and follow up from a specialty pharmacist as needed or the standard of care.
- Trial name
- NCT03709277
- Testing
- Pharmacist-Driven Intervention
- Where
- United States
- Volunteers
- 438 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Type2 Diabetes, Medication Adherence
Improving Diabetes Medication Adherence for African Americans in Madison and Milwaukee Through Peer Support
The burden of diabetes is higher among African Americans (AAs) in Wisconsin as hospitalization rates for diabetes complications such as stroke and amputations are four times higher than whites and has worsened by 334% since 2011.
- Conditions
- Type2 Diabetes, Medication Adherence, Medication Nonadherence, Peer Support
- Trial name
- NCT04028076
- Testing
- Peers Supporting Health-Literacy, Self Efficacy, Advocacy and Adherence
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Diabetes Mellitus, Type 1, Noncompliance, Patient
Feasibility and Effectiveness of Real-time, Remote Continuous Glucose Monitoring in Adolescents With Poorly Controlled Type 1 Diabetes
Adolescents with Type 1 Diabetes (age 13-18 years, T1D duration >6 months managed on insulin) and poor glycemic control will wear a blinded CGM to obtain baseline data.
- Trial name
- NCT04540536
- Testing
- Continuous Glucose Monitoring, Secure texting
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center
Bipolar Disorder, Schizophrenia
Event Marker Ingested To Trigger Event Recorder 3.0 Psychiatry Study
Feasibility study of using a digital health feedback system (DHFS) to monitor medication-taking and physiologic and behavioral parameters in patients with bipolar disorder or schizophrenia.
- Trial name
- EMITTER3PSY (NCT01804257)
- Testing
- Digital Health Feedback System
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Proteus Digital Health, Inc.
Type 2 Diabetes Mellitus, Medication Adherence
STUDIIO-Diabetes Pilot: STUdy of Drug Insurance to Improve Outcomes of Diabetes
Canada is the only country with a universal health insurance system that does not provide coverage for prescription drugs to all residents. One-third of working-age Canadians have no insurance.
- Conditions
- Type 2 Diabetes Mellitus, Medication Adherence, Medication Compliance, Medication Nonadherence
- Trial name
- NCT03804905
- Testing
- No-cost Medications
- Volunteers
- 144 people
- Sponsor
- Sunnybrook Health Sciences Centre
Bipolar Disorder
Customized Medication Adherence Enhancement for Adults With Bipolar Disorder
This study is a modular intervention that is intended to improve treatment adherence among individuals with bipolar disorder on atypical antipsychotic therapy who have been identified as having treatment adherence problems.
- Trial name
- UH CAE (NCT00830310)
- Testing
- Psychoeducation module, Substance use module, Improved communication/rapport with provider module
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University Hospitals Cleveland Medical Center
Medication Adherence, Medication Nonadherence
Collaborative Nurse-pharmacist Counseling for Self-administered Biologics
The goal of this clinical trial is to learn if nurse-pharmacist counseling can improve patient knowledge and confidence and prevent side effects in patients who start a biologic medication in-office and later continue the…
- Conditions
- Medication Adherence, Medication Nonadherence, Adverse Drug Event
- Trial name
- COLLAB (NCT05798104)
- Testing
- Collaborative nurse-pharmacist counseling
- Where
- United States
- Sponsor
- Tonia Carr
Asthma in Children, Nonadherence, Medication
Symptom-driven ICS/LABA Therapy for Adolescent Patients With Asthma Non-adherent to Daily Maintenance Inhalers
Inhaler nonadherence is a common problem that has been estimated to account for approximately 60% of all asthma-related hospitalizations.
- Trial name
- NCT05689983
- Testing
- Maintenance ICS and Symptom Driven SABA, Symptom-driven budesonide/formoterol combination
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Washington University School of Medicine
Medication Adherence, Compliance
Compliance/Adherence After Kidney Transplant, With or With Out Med-O-Wheel™.
Background: Adherence to the immunosuppressive drug regimen is critical to the outcome after an organ transplant. Patients need to take their prescribed medications and attend their appointments with the doctor.
- Conditions
- Medication Adherence, Compliance, Medication Nonadherence, Communication
- Trial name
- C/A (NCT01709097)
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska University Hospital
HIV Infections, Depression
Task Shifting to Treat Depression and HIV Medication Nonadherence in Low Resource Settings
A hybrid effectiveness-efficacy trial to evaluate a stepped care task shifted intervention to treat depression and HIV medication nonadherence in low resource settings in rural Zimbabwe.
- Trial name
- NCT04018391
- Testing
- Stepped care for nonadherence and depression, Enhanced Usual Care
- Where
- Zimbabwe
- Volunteers
- 280 people
- Sponsor
- King's College London
Schizophrenia, Medication Nonadherence
Reducing the Burden of Chronic Psychotic Disorders in Tanzania (CAPACITY)
The proposed, three phase project will refine and test a first-ever care approach in SSA that combines LAI with a behavioral program specifically intended to promote medication adherence in chronic psychotic disorders (CPDs).
- Conditions
- Schizophrenia, Medication Nonadherence, Schizo Affective Disorder
- Trial name
- CAPACITY (NCT04327843)
- Testing
- Customized Adherence Enhancement, Haloperidol Decanoate
- Where
- Tanzania
- Volunteers
- 22 people
- Sponsor
- Case Western Reserve University
Hypertension
Pharmacy Implementation Trial: Adherence to Antihypertensive Therapy
The purpose of this study is to determine the effectiveness of maximal support of community pharmacies to implement a pharmaceutical care model for establishing and - if necessary - improving adherence to antihypertensive…
- Trial name
- NCT00460343
- Testing
- extensive implementation programme, control
- Volunteers
- 57 people
- Sponsor
- Radboud University Medical Center
Patient Noncompliance
Customized Adherence Enhancement Plus Long-acting Injectable Antipsychotic
Psychotropic medications are a cornerstone of treatment for individuals with schizophrenia and schizoaffective disorder, however rates of full or partial non-adherence can exceed 60%.
- Trial name
- CAE-L (NCT01152697)
- Testing
- haloperidol decanoate, haloperidol, Customized Adherence Enhancement
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University Hospitals Cleveland Medical Center
Noncompliance
Efficacy of Parent-Child Interaction Therapy With Autism Spectrum Disorder
The aim of the current proposal is to determine if the PCIT treatment manual can be successfully utilized for preschoolers with ASD and disruptive behavior (across a range of intellectual functioning levels) and to evaluate its…
- Trial name
- PCIT (NCT02088905)
- Testing
- Parent Child Interaction Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Pittsburgh
Opiate Addiction, Medication Non-adherence
Using Artificial Intelligence To Monitor Medication Adherence in Opioid Replacement Therapy
This study uses an artificial intelligence platform to automatically confirm medication ingestion. The Health Insurance Portability and Accountability Act (HIPAA)-compliant platform can be downloaded as an 'app' onto any…
- Conditions
- Opiate Addiction, Medication Non-adherence, Addiction, Opioid Dependence
- Trial name
- NCT02243670
- Testing
- AiCure monitoring and intervention
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- AiCure
Atrial Fibrillation
Specific Anti Factor Xa Activity Dosage to Enhance Detection of Nonadherence in Atrial Fibrillation Patients
Direct oral anticoagulants (DOAC), an inhibitor of factor IIa (dabigatran) or factor Xa inhibitors (rivaroxaban, apixaban) are an alternative to treatment with warfarin in patients with atrial fibrillation (AF) non-valvular .
- Trial name
- NCT02925247
- Testing
- Adherence to oral anticoagulant treatment
- Volunteers
- 150 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Ulcerative Colitis
Methods of Improvement Adherence With Therapy in Ulcerative Colitis.
Ulcerative Colitis is associated with a significantly increased risk of colorectal cancer. This risk can be reduced through regular medication with 5ASA compounds.
- Trial name
- NCT00398593
- Testing
- Range of electronic pill dispensers with alarms
- Volunteers
- 80 people
- Sponsor
- University Hospitals, Leicester