Clinical trials: Noninvasive Positive Pressure Ventilation;
COPD
Analyse the Correlation Between sEMG and EMGdi
The most significant pathophysiology change of COPD patients is persistent incompletely reversible airflow obstruction and increased lung volume. As a result, the work of breathing(WB) and neural respiratory drive (NRD)increased.
- Trial name
- NCT03268616
- Testing
- inspiratory threshold load device and NPPV
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Acute Respiratory Failure With Hypoxia
Positive Pressure During Bronchoscopy
It has been demonstrated the application of noninvasive positive pressure ventilation (NPPV) to assist spontaneous breathing through a face mask during fiberoptic bronchoscopy (FOB) with bronchoalveolar lavage (BAL) in severely…
- Trial name
- NCT02167542
- Testing
- Noninvasive Positive Pressure Ventilation, CPAP valve (Boussignac)
- Where
- Portugal
- Volunteers
- 24 people
- Sponsor
- Hospital Sao Joao
Respiratory Failure, Healthy
Evaluation of Different Interfaces for Noninvasive Positive Pressure Ventilation (NPPV)
In this study the investigators aimed to study the ventilatory performance of different interfaces during NPPV delivering.
- Trial name
- NCT00297986
- Testing
- Helmet
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital
Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea
Continuous Positive Airway Pressure Versus Noninvasive Ventilation in Patients With Overlap Syndrome
The purpose of this study is to determine if Bipap should assume a standard-of-care role in the management of overlap syndrome.
- Conditions
- Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea, Overlap Syndrome
- Trial name
- OS (NCT01427673)
- Testing
- Bipap procedure
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- United States Air Force
Acute Hypoxemic Respiratory Failure, High-Flow Nasal Oxygen Therapy
Effects of Face Mask Continuous Positive Airway Pressure Vs. Noninvasive Ventilation Vs. High-flow Nasal Oxygen on Intubation-free Survival in Acute Hypoxemic Respiratory Failure: the TRIPOD Randomized Clinical Trial
Acute hypoxemic respiratory failure (AHRF) is a common indication for admission to an intensive care unit (ICU), with mortality exceeding 50% in cases where invasive mechanical ventilation is needed.
- Conditions
- Acute Hypoxemic Respiratory Failure, High-Flow Nasal Oxygen Therapy, Noninvasive Ventilation, Continuous Positive Airway Pressure (CPAP)
- Trial name
- TRIPOD (NCT06795971)
- Testing
- Continuous Positive Airway Pressure, High-flow nasal oxygen, Non-invasive ventilation
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- Southeast University, China
Pneumonia, Human Immunodeficiency Virus (HIV)
CPAP Improving Mortality for Pneumonia in African Children Trial
Pneumonia mortality rates in African countries like Malawi are high and increased further in children -exposed or infected with human immunodeficiency virus (HIV) as well as those that are severely malnourished or severely…
- Conditions
- Pneumonia, Human Immunodeficiency Virus (HIV), Malnutrition, Hypoxemia
- Trial name
- IMPACT (NCT02484183)
- Testing
- bubble continuous positive airway pressure (CPAP)
- Where
- Malawi
- Volunteers
- 646 people
- Sponsor
- Johns Hopkins University
Acute Lung Injury
Early Use of Noninvasive Positive Pressure Ventilation for Intro-pulmonary Acute Lung Injury
To assess the safety and efficacy of noninvasive positive pressure ventilation for patients with intro-pulmonary pulmonary acute lung injury and compare this with high-concentration oxygen therapy.
- Trial name
- NCT01581229
- Testing
- noninvasive positive pressure ventilation, oxygen therapy
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Beijing Hospital
Premature Birth
Changes in Respiratory Effort in Preterm Infants
Continuous Positive Airway Pressure (CPAP) is used to treat preterm infants with an immature respiratory center and having respiratory distress. CPAP requires intensive care monitoring and special qualified staff.
- Trial name
- NCT02014493
- Testing
- High Flow Nasal Cannulae (HFNC), Continuous Positive Airway Pressure (CPAP)
- Where
- Norway
- Volunteers
- 21 people
- Sponsor
- St. Olavs Hospital
Pulmonary Disease, Chronic Obstructive (COPD), Chronic Respiratory Failure With Hypercapnia
RESET-COPD Cohort: Real-Time Monitoring and Early Warning in COPD Patients Receiving Home NPPV
This is a multicenter prospective cohort study designed to develop and validate a multisensor-based real-time monitoring and intelligent early warning model for acute exacerbations in patients with chronic obstructive pulmonary…
- Conditions
- Pulmonary Disease, Chronic Obstructive (COPD), Chronic Respiratory Failure With Hypercapnia, Noninvasive Ventilation
- Trial name
- RESET-COPD (NCT07701096)
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Beijing Chao Yang Hospital
Noninvasive Ventilation
NHFOV Vs NIPPV Post-extubation in Preterm Neonates
comparison between Noninvasive Intermittent Positive Pressure Ventilation (NIPPV) and Noninvasive High Frequency Oscillation Ventilation (NHFOV) post-extubation in preterm neonates as regards the efficacy and their possible…
- Trial name
- NCT06620107
- Testing
- noninvasive high frequency oscillation ventilation, noninvasive positive pressure ventilation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Kafrelsheikh University
Status Asthmaticus
Early Noninvasive Positive Pressure Ventilation in Children With Status Asthmaticus
Status asthmaticus is recognized as a common cause of morbidity in children in the United States. In recent years, hospitalization rates have reached an all time high.
- Trial name
- NCT01188473
- Testing
- NPPV plus standard of care
- Where
- United States
- Sponsor
- Southern Illinois University
Premature Birth, Respiratory Distress Syndrome, Newborn
High-Flow Nasal Cannula Versus Nasal CPAP as Primary Support in Preterm Respiratory Distress Syndrome
This single-center randomized controlled trial compared heated humidified high-flow nasal cannula (HHHFNC) with nasal continuous positive airway pressure (nCPAP) as primary noninvasive respiratory support in preterm infants…
- Trial name
- NCT07693530
- Testing
- Group 1 Heated humidified high-flow nasal cannula (HHHFNC), Group 2 Nasal continuous positive airway pressure (nCPAP)
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Kayseri City Hospital
Respiratory Distress, Lung Injury
Infant Pulmonary Mechanics: High Flow Nasal Cannula Versus Nasal CPAP
This study is designed to evaluate the effect of heated humidified high flow nasal cannula (HHHFNC) as compared to noninvasive nasal continuous positive airway pressure (NCPAP) on lung function as a measure of lung injury in…
- Trial name
- NCT01939067
- Testing
- Heated Humidified High Flow Nasal Cannula, Nasal Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Extubation Failure, Acute Respiratory Failure Post Extubation
Prevention of Reintubation by Using Noninvasive Positive Pressure Ventilation
Child extubation failure range from 4.1% to 19%. Studies in adults and children showed that extubation failure increases mortality mainly in those who need reintubation as this is a invasive procedure associated with many…
- Trial name
- NCT00977002
- Testing
- Positive Pressure Noninvasive ventilation, Inhalatory O2
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Acute Respiratory Distress Syndrome
Non-Invasive Positive Pressure Ventilation and Adult Respiratory Distress Syndrome (ARDS)
Background and objective: To determine the efficacy of non-invasive positive pressure ventilation (NPPV) and its effects upon intubation rate and mortality in ARDS.
- Trial name
- NPPV (NCT00644930)
- Testing
- the application of NPPV, invasive ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Eskisehir Osmangazi University
Metabolic Syndrome
NPPV on Inflammatory Markers and Sleep in Severe Obese Patients With Metabolic Syndrome Undergone to Bariatric Surgery
Obesity is currently one of the most serious public health problems. Its prevalence is increasing sharply in recent decades, even in developing countries, leading to global epidemiology condition.
- Trial name
- NCT02409173
- Testing
- Noninvasive positive airway pressure flow generator device, Bariatric Surgery
- Where
- 3 sites in Brazil
- Volunteers
- 17 people
- Sponsor
- Centro Universitário de Anapolis
Heart Failure
Cardiac Rehabilitation and Noninvasive Ventilation in Heart Failure
The study aims to demonstrate the efficacy of NIV continuously in cardiac rehabilitation programs, improvement of exercise tolerance, with consequent reflection in functional capacity and quality of life of this population.
- Trial name
- NCT02811146
- Testing
- Bilevel Positive Pressure Airway, Heart rehabilitation
- Where
- 2 sites in Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco
Continuous Positive Airway Pressure, Noninvasive Ventilation
Effects of a Therapeutic Education Program on Treatment Adherence Among Patients Prescribed At-home CPAP or At-home NIV
The primary objective of this study is to study the effect of therapeutic education on patient adherence for at-home continuous positive airway pressure (CPAP) or at-home non-invasive ventilation.
- Trial name
- APARDetp (NCT03151317)
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Montpellier
Respiratory Insufficiency, Chronic Obstructive Pulmonary Disease
Comparative Study of Non-Invasive Mask Ventilation vs Cuirass Ventilation in Patients With Acute Respiratory Failure.
Non-invasive ventilation has become increasingly important in the management of patients with acute respiratory failure. One of its major goals is to prevent the need for invasive ventilation, which is associated with numerous…
- Conditions
- Respiratory Insufficiency, Chronic Obstructive Pulmonary Disease, Pneumonia, Pulmonary Edema
- Trial name
- NCT00331656
- Testing
- Non-invasive positive pressure mask ventilators, Extrathoracic biphasic cuirass ventilator (RTX, Hayek)
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hadassah Medical Organization
Heart Failure
CPAP Versus Bi-level in Chronic Heart Failure
Introduction: Dyspnea and fatigue are the main clinical symptoms of heart failure and primarily responsible for exercise intolerance found in this syndrome.
- Trial name
- CHF (NCT03287141)
- Testing
- Shuttle walk test, Noninvasive ventilation (Bi-pap), Noninvasive ventilation (CPAP)
- Volunteers
- 18 people
- Sponsor
- Patri-cia Angelica de Miranda Silva Nogueira