Clinical trials: Normal Healthy
Healthy
A Study To Estimate The Amount Of CP-690,550 (Study Drug) That Is Absorbed Into The Blood Of Healthy Subjects Following Oral Administration Of CP-690,550 In Tablet Form
In this study, a 10 mg dose of CP-690,550 will be given to study subjects on two separate occasions by two different routes of administration: One time by mouth in tablet form and one time by vein (intravenous form).
- Trial name
- NCT01143805
- Testing
- Tasocitinib 10 mg oral tablet, Tasocitinib 10 mg IV Infusion
- Where
- Singapore
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Psoriasis
A Study of PRCL-02 in Healthy Volunteers and Plaque Psoriasis
This study consists of three parts: single oral dose escalation in healthy volunteers (Part A), and multiple oral dose escalations in healthy volunteers (Part B) and in participants with chronic plaque psoriasis (Part C)
- Trial name
- NCT03062618
- Testing
- PRCL-02
- Where
- 6 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- PRCL Research Inc.
Pharmacokinetics
Phase I Study PK Study With OXP005 and Naprosyn
The Sponsor is developing a new form of naproxen (the study drug, OXP005), for the potential treatment of rheumatic and painful conditions.
- Trial name
- NCT02351024
- Testing
- OXP005, Naprosyn®
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Oxford Pharmascience Ltd
Ataxia, Cerebrovascular Accident
PET Scan to Study Brain Control of Human Movement
Positron Emission Tomography (PET) is a technique used to investigate activity in areas of the brain. The PET technique allows researchers to study the normal processes in the brain (central nervous system) of normal individuals…
- Conditions
- Ataxia, Cerebrovascular Accident, Healthy, Movement Disorder
- Trial name
- NCT00001324
- Where
- United States
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy Participants, Rheumatoid Arthritis (RA) Prevention
Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis
The purpose of this study is to determine if hydroxychloroquine (HCQ) is safe and effective for the prevention of future onset of rheumatoid arthritis (RA) in individuals who have elevations of an autoantibody, anti-cyclic…
- Trial name
- StopRA (NCT02603146)
- Testing
- Hydroxychloroquine
- Where
- 14 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy
A Relative Bioavailability Study of Bupropion XL 150 mg Tablets Under Fasting Conditions
To compare the rate and extent of absorption of Abrika Bupropion 150 mg XL Tablet to that of Wellbutrin XL® 150 mg Tablet after a single, one-tablet dose in fasted subjects.
- Trial name
- NCT00863941
- Testing
- Abrika Bupropion 150 mg XL Tablet, single dose, Wellbutrin XL® 150 mg Tablet, single dose
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Actavis Inc.
Hepatic Impairment
Impact of Hepatic Impairment on the Pharmacokinetics of Deferasirox.
This study is to assess the pharmacokinetics of deferasirox in hepatically impaired patients compared to healthy volunteers.
- Trial name
- NCT00432627
- Testing
- Deferasirox
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Osteoporosis
A Dose Selection Study of Oral Recombinant Salmon Calcitonin (rsCT) in Normal, Healthy, Postmenopausal Women
This study compares the performance of different doses of oral recombinant salmon calcitonin (rsCT).
- Trial name
- NCT00620854
- Testing
- Recombinant Salmon Calcitonin (rsCT), Oral Tablet, Nasal Spray
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tarsa Therapeutics, Inc.
Major Depressive Disorder
Safety and Tolerability of Zelquistinel in Normal Human Volunteers
To evaluate the safety and tolerability of single ascending doses of zelquistinel in normal human volunteers
- Trial name
- NCT04981561
- Testing
- zelquistinel
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Syndeio Biosciences, Inc
Healthy
The Effect of Pressure Ulcer Education on the Knowledge Level of the Relatives of the Patients
The purpose of this randomized controlled trial, which included pretest and posttest, was to examine the effectiveness of pressure ulcer prevention and care education given to caregivers of patients treated in a palliative care…
- Trial name
- NCT05979402
- Testing
- Training group Face-to-face pressure ulcer training, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Glaucoma, Cataract
Eye Drop Dispensers: Safety, Efficacy and Comfort.
One aspect to eye drop adherence is successful instillation of the drops; however, it is well known that many patients struggle with this task.
- Conditions
- Glaucoma, Cataract, Healthy Subjects
- Trial name
- NCT03417453
- Testing
- Eye Drop Dispenser TYPE Opticare, Eye Drop Dispenser Autodrop
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Healthy
Acapella With Nebulization in Normal Subjects
Background: Devices used to facilitate mucus mobilization have been target of several controversies and mainly a few scientific studies that endorse the use of those equipments.
- Trial name
- NCT01102166
- Testing
- Acapella with nebulization
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Dry Eye Syndrome, Sjogren's Syndrome
Dry Eye Syndrome, Healthy Control, Sjögren's Syndrome and Other Inflammation Disease in Taiwan Biobank
The comprehensive analysis of health records, TCM constitution, biomarker, and whole-genome sequencing among dry eye syndrome, healthy control, Sjögren's syndrome and other inflammation disease in Taiwan: an integrated analysis…
- Conditions
- Dry Eye Syndrome, Sjogren's Syndrome, Healthy Control, Inflammation
- Trial name
- NCT03938207
- Testing
- Whole-genome genotyping, Whole-genome sequencing, TCM pattern
- Where
- Taiwan
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Normal Healthy
Topical Multiple Ascending Dose Study for PF-06423264
The current study is the first clinical trial proposed with PF-06423264. It is designed to evaluate the safety, tolerability, and pharmacokinetics (PK) following administration of multiple ascending doses of PF-06423264 to…
- Trial name
- NCT02778477
- Testing
- PF-06423264
- Where
- Belgium
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Pfizer
Mobile Applications, Healthy Volunteers
Standardized Home Spirometry Method in Normal Population
This study was designed to evaluate the feasibility of using a Standardized Home Spirometry (SHS) Method to develop normal range values, to detect a variance (i.e., a value outside of that normal range), to evaluate a variance…
- Conditions
- Mobile Applications, Healthy Volunteers, Feasibility Study
- Trial name
- NCT03945500
- Testing
- Investigational Mobile Medical Software Application & IT Dashboard Application, FDA approved Bluetooth spirometer, FDA approved pulse oximeter
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Healthy
A Study to Examine the Glycemic Response of Corn and Soy Tortillas in Healthy Individuals
Tortillas are a staple food in several cultures and are widely used to make tacos, burritos, and enchiladas. These foods are gaining a significant segment of the North American fast food and restaurant industry.
- Trial name
- SOYT-2013 (NCT01828671)
- Testing
- Oral Glucose Solution 296 mls, Corn Tortilla, Low Soy Flour Corn Tortilla
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hepatic Impairment
Pharmacokinetics and Safety of ALKS 5461 in Healthy Subjects and Subjects With Hepatic Impairment and Normal Hepatic Function
This study will evaluate the effect of various degrees of hepatic function on the pharmacokinetics and safety of ALKS 5461.
- Trial name
- NCT02452801
- Testing
- ALKS 5461
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alkermes, Inc.
Tourette's Syndrome, Chronic Motor Tic Disorder
Brain Activation in Vocal and Motor Tics
This study will investigate the brain areas that are activated by vocal and motor tics in patients with Tourette's syndrome and other tic disorders. Tics are involuntary repetitive movements similar to voluntary movements.
- Conditions
- Tourette's Syndrome, Chronic Motor Tic Disorder, Chronic Motor Vocal Disorder
- Trial name
- NCT00026000
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Tuberculosis
Escalating Single-dose Safety, Tolerability, and Pharmacokinetics of SQ109 in Healthy Volunteers
This is a phase 1, "first in man" study to evaluate single oral doses (5-300 mg) of SQ109, a new investigational drug being developed for treatment of tuberculosis.
- Trial name
- NCT01585636
- Testing
- SQ109
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sequella, Inc.
Dyslipidemia
Saturated Fatty Acids and HDL Metabolism
The purpose of this study is to determine whether palmitic acid (C16:0) and stearic acid (C18:0) have different effects on HDL metabolism during the fasted state.
- Trial name
- NCT02835651
- Testing
- Palmitic acid, Stearic acid
- Where
- Netherlands
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
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