Clinical trials: Normal Healthy
Rheumatoid Arthritis
Effect of a High-fat Meal on the Pharmacokinetics of SHR0302 and Mass Balance Study in Healthy Subjects
The purpose of this open-label, randomized, two-period, two-treatment (single doses of 10 mg SHR0302 fasted or fed), crossover study was to evaluate the effect of a high-fat meal on the pharmacokinetics of SHR0302 and mass…
- Trial name
- NCT02892370
- Testing
- SHR0302
- Where
- China
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Cancer, Healthy
Collection and Distribution of Biospecimens for Novel Research Uses
iSpecimen aims to create a clinical partner network of hospitals, laboratories, academic institutions, and other healthcare organizations ("institutions") capable of providing researchers and educators ("researchers") with…
- Conditions
- Cancer, Healthy, Gastrointestinal Complication, Autoimmune Diseases
- Trial name
- NCT03848962
- Where
- 2 sites in United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- iSpecimen Inc
Healthy, Liver Disease
Magnetic Resonance Imaging of Blood Flow in the Liver and Abdomen
This study will use magnetic resonance imaging (MRI) to examine blood flow patterns in the arteries and veins of the liver and abdomen.
- Trial name
- NCT00001719
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Skin Diseases
Pilot Investigation of a Multinutrient Supplement on Skin Aging and Aging Metabolites in Healthy Women
We are seeking healthy female volunteers to determine if multinutrient supplementation affects visible signs of skin aging as well as blood measurements of aging. We are seeking smokers and non-smokers.
- Trial name
- NCT00541931
- Testing
- Dietary Supplement: LifePak Nano
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Stanford University
Behaviour
Evaluation of Behaviour in Parkinson's Disease. Normal Values in Healthy Subjects
Non-motor symptoms like mood fluctuations and behavioral disorders are frequent in Parkinson's disease. They may be induced by both the pathology and the dopaminergic treatment and must be considered in treatment policies.
- Trial name
- ECMP (NCT02820428)
- Testing
- Healthy participants
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Prostate Cancer
Update and Biodistribution of [F-18]FMDHT pET/CT in Normal Healthy Volunteers and Patients With Metastatic Prostate Cancer - A First in Human Subject Study With [F-18] FMDHT
Prostate cancer represents a significant health problem in the United States. This year 179,000 men in the United States will be diagnosed with prostate carcinoma and approximately 25% of them will die of the disease.
- Trial name
- NCT01724619
- Testing
- [F-18] fluorinated dihydrotestosterone (FDHT)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Parkinson's Disease
Effect of Stimulus Rate on Cognitive and Motor Activity in Young Subjects, Elderly Subjects, and Patients With Parkinson's Disease
The purpose of this study is to investigate how changes in the brain associated with Parkinson's disease influence the control of motor and thinking speed.
- Trial name
- NCT00026598
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cytomegalovirus Infection
Safety and PK of MBX-400 (Cyclopropavir) in Normal Volunteers
This is a phase I safety, PK and food effect study of the CMV drug. In part 1 of the study, subjects will receive one of four dosage strengths of MBX-400 (100 mg once daily, 350 mg once daily; 750 mg once daily; and 1000 once…
- Trial name
- NCT02454699
- Testing
- MBX400
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Breast Cancer, Kinesiophobia
Breast Cancer and Kinesiophobia and Physical Activity
Breast cancer is the most common type of cancer in women worldwide. A significant number of breast cancer survivors develop many complications.
- Trial name
- NCT05090098
- Testing
- None intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Systemic Sclerosis
IgG-4 Levels in Systemic Sclerosis
This is an observational - non interventional study. The investigators will compare IgG4 levels of 80 healthy donors (from Israel blood bank - MDA) and 80 Systemic Sclerosis patients from Meir Medical Center.
- Trial name
- SSc-IgG4 (NCT04219592)
- Testing
- IgG4 measurement (non-interventional, just obtaining data from medical records)
- Where
- Israel
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Healthy
Drug-Drug Interaction Study: ASP2151 and Ciclosporin
ASP2151 is an experimental treatment for herpes. Patients undergoing organ and tissue transplantation may be prescribed ciclosporin to suppress their immune system to give the transplant an increased chance of not being rejected.
- Trial name
- NCT02280421
- Testing
- ASP2151 400mg + 100mg ciclosporin, ASP2151 1200mg + 100mg ciclosporin
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Maruho Europe Limited
Healthy Volunteers, Patients
Magnetic Resonance Imaging (MRI) Ofl Volunteers
Magnetic resonance is an imaging technique that uses magnetic fields and radio waves to create images of the body. The technology used in magnetic resonance imaging continues to improve.
- Trial name
- NCT00001711
- Testing
- MRI
- Where
- United States
- Volunteers
- 1,229 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy
ACY-7 Oral Administration of Acyline
We propose oral dosing of gastrointestinal permeation enhancement technology [GIPET] enhanced oral acyline at 20 mg everyday for one week to determine the steady-state (multiple-dose) pharmacokinetics of oral acyline in four…
- Trial name
- ACY-7 (NCT00603187)
- Testing
- Acyline
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Washington
Healthy
PK, Safety & Tolerability of CyCol® Versus Sandimmune® in Healthy Subjects
The aim of this Phase I, single centre, multi stage study is to evaluate the safety, tolerability, pharmacokinetics and relative colonic mucosal concentrations of cyclosporine capsules (CyCol®) compared to intravenous…
- Trial name
- CYC102 (NCT02130414)
- Testing
- Sandimmun® IV, CyCol® capsules
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Sigmoid Pharma
Mechanical Ventilation Complication
Determination of Normal Values of Regional Pulmonary Strain Using a New Ultrasonographic Tool in Healthy Volunteers
Mechanical ventilation is frequently used in the operating room and the intensive care settings. Although essential in many cases, mechanical ventilation can be responsible for ventilator-induced lung injury (VILI).
- Trial name
- Strain (NCT04194346)
- Testing
- Lung ultrasound
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Renal Impairment, Healthy Volunteers
A Study of ASP0367 in People With Kidneys That do Not Work Well and in Healthy People
This study is for adults whose kidneys do not work well (renal impairment) and adults whose kidneys work normally. This study will provide more information on a potential new treatment, called ASP0367.
- Trial name
- NCT05117294
- Testing
- Bocidelpar
- Where
- 4 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Global Development, Inc.
Healthy Volunteers
Skin Barrier Function in Women Using UV Nail Lamps
The goal of this observational study is to compare objective parameters of skin barrier function between healthy adult women who regularly use UV lamps during nail treatments and women who do not use UV lamps.
- Trial name
- NCT07700186
- Where
- Croatia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Rheumatoid Arthritis
Anterior Shoulder US - a New Access
1. Investigate Gleno-Humeral Joint (GHJ) by anterior approach: A - Measurement of GHJ thickness at 3 points and average value calculation on body supine position and with arm supinated, maximal externally rotated with elbow angle…
- Trial name
- NCT01746966
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Pain, Normal Physiology
Neural and Psychological Mechanisms of Pain Perception
Background: Painful stimuli cause changes in a network of brain regions called the "Pain Matrix." But most of these regions respond to many other stimuli, not just pain.
- Conditions
- Pain, Normal Physiology, Healthy Volunteers
- Trial name
- NCT02446262
- Testing
- Instructions, Attention, Thermal Pain
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Erythema
Study to Evaluate the Sensitizing Potential of MOB015B in Healthy Subjects Using a Repeat Insult Patch Test Design
A Randomized, Controlled Study to Evaluate the Sensitizing Potential of MOB015B in Healthy Subjects Using a Repeat Insult Patch Test Design To evaluate the sensitization potential
- Trial name
- RIPT (NCT06369727)
- Testing
- MOB015B, MOB015B vehicle, Negative irritant solution of 0.9% saline
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Moberg Pharma AB
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