Clinical trials: Normal Individuals
Atopic Dermatitis, Alopecia Areata
Treatment of Atopic Dermatitis and Alopecia Areata With Abrocitinib in Individuals With Down Syndrome
This is a single-center, open-label, basket phase 2b trial that will enroll Down Syndrome (DS) participants with at least one inflammatory skin condition (Atopic Dermatitis (AD) and/or Alopecia Areata (AA)).
- Trial name
- NCT07242638
- Testing
- Abrocitinib
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Spinal Cord Injuries, Paraplegia
Interactive Telehealth for Wheelchair Users
During typical daily activity, people with established spinal cord injury perform significantly fewer pressure-relief maneuvers than the recommended frequency while overestimating their adherence on recall surveys of pressure…
- Conditions
- Spinal Cord Injuries, Paraplegia, Pressure Ulcer, Buttock
- Trial name
- NCT04266808
- Testing
- An interactive telehealth monitoring and biofeedback system, Education Control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Rancho Research Institute, Inc.
Stroke
Effects of Device-assisted Practice of ADL on Arm/Hand Recovery in Individuals With Moderate to Severe Stroke
A large number of post-stroke survivors cannot functionally use their paretic upper extremity (UE). This study therefore investigates effects of device-assisted practice of activities of daily living (ADL) in a close-to-normal…
- Trial name
- NCT04077073
- Testing
- ReIn-Hand, Robot
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Northwestern University
Acne
Safety and Efficacy of Skincare Products for Managing Mild to Moderate Acne in Individuals With Sensitive Skin
To investigate the safety and efficacy of a skincare regimen in individuals with mild to moderate acne and sensitive skin. The study duration is 4 weeks and the skin assessment will be carried out at baseline and week 4.
- Trial name
- NCT07749469
- Testing
- Cleanser, Toner, Serum
- Where
- Malaysia
- Volunteers
- 34 people
- Sponsor
- USMARI Research & Innovation Centre
Idiopathic Pulmonary Arterial Hypertension, Heritable Pulmonary Arterial Hypertension
Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals
Pulmonary arterial hypertension (PAH) is a severe disease with a delayed diagnosis and markedly elevated mortality. High-risk populations, such as those with known genetic defects, provide a unique opportunity to determine the…
- Conditions
- Idiopathic Pulmonary Arterial Hypertension, Heritable Pulmonary Arterial Hypertension, Unaffected Mutation Carriers: Healthy Participants With a Known BMPR2 Gene Mutation and Normal Pulmonary Pressure and RV Function on Echo, Healthy Individuals With no Cardiopulmonary Disease
- Trial name
- RARE-PAH (NCT05584722)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Vanderbilt University Medical Center
Rheumatoid Arthritis, Health Literacy
Health Literacy, Rational Drug Use, and Cyberchondria in Rheumatic Diseases
Purpose: This study aimed to evaluate rational drug use (RDU), health literacy (HL), and cyberchondria levels among individuals diagnosed with inflammatory rheumatic diseases, and to investigate the factors associated with these…
- Conditions
- Rheumatoid Arthritis, Health Literacy, Rational Drug Use, Cyberchondria
- Trial name
- NCT06993935
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Gulseren Demir Karakilic
Thin Hair, Hair Loss
Study to Evaluate Xtresse Serum in Individuals With Thinning Hair
The goal of this study is to determine how safe and effective it is to improve hair growth by applying a serum daily on the scalp of men and women with thinning hair. The main aims of this trial are: 1.
- Conditions
- Thin Hair, Hair Loss, Alopecia, Thinning Hair
- Trial name
- NCT07228156
- Testing
- Xtresse Serum
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Restore Biologics Holdings, Inc. dba Xtressé
Hamstring Muscle Tightness, Muscle Strength
The Effects of Instrument-Assisted Soft Tissue Mobilization in Sedentary Individuals With Hamstring Tightness
The aim of this study will be to investigate and compare the effects of static stretching exercise, Instrument Assisted Soft Tissue Mobilization (IASTM), and functional IASTM techniques on hamstring muscle shortness, pain…
- Conditions
- Hamstring Muscle Tightness, Muscle Strength, Pain Threshold
- Trial name
- NCT07091383
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Cyprus International University
Rectal Cancer, Breast Cancer
Computer-Based Comprehensive Geriatric Assessment in Oncology for Individuals 70 or Older With Gastrointestinal Malignancies
Older individuals account for one-third of new cancer cases and cancer-related deaths in the United States. Older individuals are more susceptible to having a decrease in physical and mental function following chemotherapy…
- Conditions
- Rectal Cancer, Breast Cancer, Lung Cancer
- Trial name
- NCT00973440
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Dana-Farber Cancer Institute
Onchocerciasis
Safety and Efficacy of IDA for Onchocerciasis
This DOLF study will investigate the safety and effectiveness of IDA treatment in persons with onchocerciasis when it is administered after pre-treatment with ivermectin to clear or greatly reduce microfilariae from the skin and…
- Trial name
- DOLF IDA/Oncho (NCT04188301)
- Testing
- IVM w/ ALB, Single dose of IDA, Three daily doses of IDA
- Where
- Ghana
- Volunteers
- 154 people
- Sponsor
- Washington University School of Medicine
BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome, Breast Ductal Carcinoma In Situ
Identifying and Caring for Individuals With Inherited Cancer Syndrome
This trial examines approaches to identify and care for individuals with inherited cancer syndrome. The purpose of this study is to offer no cost genetic testing to the general public.
- Conditions
- BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome, Breast Ductal Carcinoma In Situ, Hematopoietic and Lymphoid System Neoplasm, Hereditary Neoplastic Syndrome
- Trial name
- NCT04494945
- Testing
- Biospecimen Collection, Genetic Counseling, Genetic Testing
- Where
- 2 sites in United States
- Volunteers
- 27,500 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Atopic Dermatitis Eczema, Aging
Impact of Regular Consumption of Eggs and Nutrients Fortified Eggs on Eczema Condition in Singapore Individuals
The study aims to assess the effects of daily consumption of nutrients-fortified eggs on eczema condition in Singapore individuals with eczema.
- Conditions
- Atopic Dermatitis Eczema, Aging, Diet Modification
- Trial name
- NCT06454942
- Testing
- Nutrient-fortified egg, Regular egg with habitual diet
- Where
- Singapore
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Granulomatosis With Polyangiitis, Microscopic Polyangiitis
Longitudinal Protocol for Granulomatosis With Polyangiitis (Wegener's) and Microscopic Polyangiitis
Granulomatosis with polyangiitis (Wegener's) (GPA) and microscopic polyangiitis (MPA) are two rare immune system disorders that cause the inflammation of blood vessels, or vasculitis.
- Conditions
- Granulomatosis With Polyangiitis, Microscopic Polyangiitis, Wegener's
- Trial name
- NCT00315393
- Where
- 8 sites in United States, Canada
- Volunteers
- 1,046 people
- Sponsor
- University of Pennsylvania
Raynaud Phenomenon
Beet the Cold: The Effect of Inorganic Nitrate Supplementation in Individuals With Raynaud's Phenomenon
Individuals with Raynaud's phenomenon often experience episodes of reduced blood flow to their fingers and toes during times of stress or cold exposure, causing significant discomfort and pain.
- Trial name
- NCT03129178
- Testing
- Concentrated beetroot juice
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- University of Portsmouth
Ovarian Cancer, Breast Cancer
Identifying Underserved Individuals inTexas With Hereditary Cancer Risk Using Mobile Mammography Units and Telegenetics.
Identifying women at risk for hereditary cancer potentiates prevention, early detection or personalised treatment against cancer.
- Conditions
- Ovarian Cancer, Breast Cancer, Colorectal Cancer
- Trial name
- NCT05649072
- Testing
- Genetic Testing and Counseling, Screening Form
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- M.D. Anderson Cancer Center
Instrument-assisted Soft Tissue Mobilization, Flexibility
Investigation of the Effect of Instrument Assisted Soft Tissue Mobilization Technique and Foam Roller Application in Individuals With Chronic Non-Specific Neck Pain.
Neck pain is in fourth place among the pathologies that result in the state of disability. Acute neck pain improves greatly within 2 months, while neck pain that persists for more than 3 months takes the form of chronic neck…
- Conditions
- Instrument-assisted Soft Tissue Mobilization, Flexibility, Foam Roller, Strength
- Trial name
- NCT05503602
- Testing
- Classical Physiotherapy, IASTM Technique Application, Foam Roller Technique Application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Inonu University
Breast Cancer, Breast Neoplasms
Multi-Institutional Transgender & Gender-Diverse Breast Cancer Study
There is no granular retrospective data on breast cancer in transgender and gender-diverse (TGD) persons from a contemporary and diverse American cohort.
- Conditions
- Breast Cancer, Breast Neoplasms, Breast Adenocarcinoma, Breast Cancer Stage
- Trial name
- NCT06234488
- Where
- 22 sites in United States
- Volunteers
- 125 people
- Sponsor
- Medical College of Wisconsin
Mild Cognitive Impairment
The Influence of Oral Vibrational Stimulation on Cognitive Function of Elderly Individuals
The purpose of this study is to investigate the effect of oral vibratory stimulus on the brain activity and cognitive function of elderly people with non-dementia subjects (cognitive normal, mild cognitive impairment)
- Trial name
- OVSCF (NCT02332525)
- Testing
- Oral Vibrational Stimulation
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Cervical Pain
Instrument-assisted Soft Tissue Mobilization and Kinesiotape Application in Individuals With Chronic Neck Pain.
Chronic neck pain causes errors in joint position sense. There are studies in the literature suggesting that instrument-assisted soft tissue mobilization and Kinesiotape applications improve the joint position sense.
- Trial name
- NCT04765670
- Testing
- Instrument Assisted Soft Tissue Mobilization, Kinesiotape Application
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Primary Dysmenorrhea, Dysmenorrhea
Spinal Manipulation For Menstrual Symptoms and Sleep in Individuals With Primary Dysmenorrhea
The goal of this observational study is to evaluate if spinal manipulation (SM) combined with connective tissue massage (CTM) improves pain, menstrual symptoms, depression levels, and sleep quality in women with primary…
- Trial name
- NCT06673537
- Testing
- Connective Tissue Massage (CTM), Spinal Manipulation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul University - Cerrahpasa