Clinical trials: Normal Pregnancy
Cervical Cancer, Vulvar Cancer
A Study to Evaluate Tolerability and Immunogenicity of V504 Administered Concomitantly With GARDASIL (V504-001)(COMPLETED)
The purpose of this study is to evaluate vaccine immunogenicity and how well the body tolerates V504 when given with Gardasil.
- Conditions
- Cervical Cancer, Vulvar Cancer, Vaginal Cancer, Genital Warts
- Trial name
- NCT00551187
- Testing
- V504, Comparator: Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Pre-eclampsia, Intra-uterine Growth Retardation
EG-VEGF : Potential Marker of Pre-eclampsia and / or Intrauterine Growth Restriction
The purpose of this study is to assess the potential prognostic value of seric concentrations of EG-VEGF for Pre-eclampsia and/or intrauterine growth restriction and will allow checking whether plasma levels of EG-VEGF at 14-18…
- Trial name
- EGEVE (NCT01490489)
- Testing
- blood sample and doppler Ultrasound of uterine arteries
- Where
- France
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Hyperandrogenemia, Polycystic Ovary Syndrome
Evaluation of Adrenal Androgens in Normal and Obese Girls After Suppression and Stimulation
Women with polycystic ovary syndrome (PCOS) often have irregular menstrual periods, too much facial and body hair, and weight gain. Women with PCOS also have a hard time becoming pregnant.
- Conditions
- Hyperandrogenemia, Polycystic Ovary Syndrome, Obesity
- Trial name
- NCT01421797
- Testing
- Dexamethasone, Cortrosyn
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Infertility
Influence of a Prematuration Culture With a Phosphodiesterase-3 Inhibitor (PDE3-I) on Embryonic Aneuploidy Rate and Developmental Potential
A single centre randomised controlled trial investigating the influence of a novel prematuration system (PMS) using a phosphodiesterase-3 inhibitor for in-vitro maturation of oocytes - pilot study.
- Trial name
- NCT00822874
- Testing
- prematuration culture
- Where
- Belgium
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Pregnancy Complicated by Pre-eclampsia., Normal Pregnancy
Circulating Oxidative Stress and Gestational Hypertension. Study of the Evolution of Free-radical Markers of Oxidative Stress From Before to After Childbirth in Two Groups of Women: Normal Pregnancy and Pre-eclampsia.
The aim of this study is to explore a mechanism that could potentially explain why women with a pregnancy complicated by pre-eclampsia are described as having an increased risk of cardiovascular disease later in life.
- Trial name
- NCT01907620
- Testing
- blood sample
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Melanoma, Breast Cancer
Quantifying Systemic Immunosuppression to Personalize Cancer Therapy
The Serpentine (Stratify cancER PatiENTs by ImmuNosupprEssion) project, represents the most consistent effort so far attempted to translate MDSC into clinical practise by producing an off-the-shelf compliant assay for quantifying…
- Conditions
- Melanoma, Breast Cancer, Renal Cell Carcinoma, Urinary Bladder Cancer
- Trial name
- Serpentine (NCT05621837)
- Testing
- MDSC quantification
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Breast Cancer, Cervical Cancer
Muslim Americans Reaching for Health and Building Alliances (MARHABA): Patient Navigation Intervention to Increase Breast and Cervical Cancer Screening Among Muslim Women in New York City
Studies have reported Muslims in the US and NYC face numerous language and healthcare access barriers. This is a randomized randomized controlled design will be used to test the efficacy of a Patient Navigation (PN) intervention…
- Trial name
- MARHABA (NCT03081507)
- Testing
- SM-LHW, PN-LHW
- Where
- United States
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Normal Fetal Brain Morphology
Evaluation of Brain Volume and Dimensions in Healthy Fetuses Using Obstetrics Ultrasound Examination at 14-34 Weeks of Pregnancy.
The aim of this study is to evaluate the "normal" development of cerebral cortex with quantitative measurement in low risk pregnant women
- Trial name
- NCT03186807
- Testing
- ultrasonographic scan of fetal brain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Chronic Kidney Diseases, Dialysis; Complications
Cardiac Tissue Sodium Assessment in CKD Patients Using Sodium MRI
Chronic kidney disease (CKD) is prevalent worldwide and affects around 10% of people living in developed health economies. As the kidney loses its function in patients with CKD, the kidneys are unable to filter toxins out of the…
- Conditions
- Chronic Kidney Diseases, Dialysis; Complications, Sodium Retention
- Trial name
- NCT04848636
- Testing
- Cardiac Sodium and Proton MRI
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Fibroid, Miscarriage in First Trimester
Fibroids and the Risk of Miscarriage: a Prospective Observational Study in an Early Pregnancy Population
The aim of this observational study is to whether fibroids increase the risk of miscarriage in women in our early pregnancy population.
- Conditions
- Fibroid, Miscarriage in First Trimester, Miscarriage in Second Trimester
- Trial name
- FiRM (NCT06986616)
- Where
- United Kingdom
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Nipple Infection, Nipple Discharge
Breastfeeding Education Through Clinical Demonstration for Primiparous Women to Prevent Sore Nipples and Engorgement
Several studies show that breastfeeding problems in the first days of birth pose a significant obstacle to successful breastfeeding.
- Conditions
- Nipple Infection, Nipple Discharge, Engorgement
- Trial name
- NCT06770595
- Testing
- breastfeeding positions and attachment practice.
- Where
- 6 sites in Indonesia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Adenomyosis, Leiomyoma
New Inflammation Markers for Distinguishing Uterine Adenomyosis and Leiomyoma
Both pelvic masses and preoperative diagnosis of them have still continued as an important investigation subject. It is important to discriminate the diagnoses of leiomyoma and adenomyosis before operation especially among…
- Conditions
- Adenomyosis, Leiomyoma, Inflammation
- Trial name
- NCT02997787
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Renal Impairment
A Study to Evaluate the Pharmacokinetics of VI-0521 Subjects With Renal Impairment
VI-0521, a fixed dose combination of immediate-release (IR) phentermine and controlled-release (CR) topiramate, is in Phase III clinical development as a potential therapy for obesity.
- Trial name
- NCT00768404
- Testing
- Topirmate and Phentermine
- Where
- 4 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Pregnancy, Pregnancy Complications
GROSS-HIST : Quantification of the Main Circulating Histones During Normal Pregnancy and Pregnancies With Placenta-mediated Complications
Pregnancy generates an increased thrombotic risk, and placental-mediated diseases are a risk factor for cardiovascular diseases, in particular: pre-eclampsia (PE), intrauterine growth retardation (IUGR), retroplacental hematomas…
- Conditions
- Pregnancy, Pregnancy Complications, Healthy Volunteers
- Trial name
- GROSS-HIST (NCT04205383)
- Testing
- biological analyses
- Where
- France
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Preference, Patient, Pharmacist-Patient Relations
Preferences of Patients Treated With Oral Cancer Drugs and Informal Caregivers for Pharmaceutical Consultation in Hospital
To ensure the safe use of oral anticancer drugs, oncology pharmacy consultations (OPCs) have been established in France. Their goal is to provide the patient with the means to identify, prevent and limit adverse effects and to…
- Conditions
- Preference, Patient, Pharmacist-Patient Relations, Caregiver, Cancer
- Trial name
- IMPLICATION (NCT05970471)
- Where
- France
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Insufficient Lactation
Improving Lactation Success in Black Mothers of Critically Ill Infants
Racial disparities result in Black infants in the neonatal intensive care unit (NICU) receiving less breast milk (BM) than White and Hispanic infants.1 BM improves infant health yet mothers of critically ill infants produce…
- Trial name
- NCT05147987
- Testing
- Hands free wearable breast pump
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Florida
Postpartum Complication
IMPACT: Improving Maternal Postpartum Access to Care Through Telemedicine
The purpose of this study is to compare two complex, multi-component evidence-based postpartum interventions in underserved populations of lower socioeconomic status in an effort to reduce maternal morbidity and mortality.
- Trial name
- IMPACT (NCT06218355)
- Testing
- Intensive Education, Enhanced Virtual Care
- Where
- 2 sites in United States
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Polycystic Ovary Syndrome
Obesity and Clinical Presentation of Hyperandrogenism
Polycystic Ovarian Syndrome (PCOS) is the most common endocrine disorder in reproductive women. It is estimated that 5 to 10% of women of reproductive age have PCOS.
- Trial name
- NCT01114633
- Where
- Taiwan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Endometrial Cancer, Endometrial Diseases
Virtual Reality's Role in See&Treat Hysteroscopy
The aim of the study is to evaluate the feasibility and effectiveness of virtual reality technology in outpatient hysteroscopy to improve pain and anxiety management and spread the diffusion of see \& treat philosophy.
- Conditions
- Endometrial Cancer, Endometrial Diseases, Myoma;Uterus, Endometrial Hyperplasia
- Trial name
- NCT06524934
- Testing
- Use of virtual reality during the hysteroscopic procedure
- Where
- Italy
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Federico II University
Healthy Volunteer, Renal Impairment
Renal Impairment Study of PF-06700841
The purpose of this study is to characterize the effect of kidney impairment on the blood concentrations of PF-06700841 and its major metabolite.
- Trial name
- NCT04260464
- Testing
- PF-06700841
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pfizer