Clinical trials: Normal Skin
Breast Cancer
Light Based Analysis of Developing Breast Tissue in Adolescent Girls: a Feasibility Study
The proposed pilot study attempts to investigate the feasibility of Optical Spectroscopy (OS) as a method to quantify breast tissue composition and density in adolescent females.
- Trial name
- NCT00188591
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Pressure Ulcer (PU)
The Effect of Pulse Oximeter Probe Replacement Interval on Pressure Injury Development in Intensive Care Patients
Patients admitted to intensive care units (ICUs) are at increased risk of medical device-related pressure injuries (MDRPIs) due to the prolonged use of monitoring devices.
- Trial name
- NCT07704710
- Testing
- Pulse Oximeter Probe Repositioning Every 2 Hours, Pulse Oximeter Probe Repositioning Every 4 Hours
- Where
- Turkey (Türkiye)
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- Emine Arici Parlak
Juvenile Idiopathic Arthritis
Pain in Juvenile Arthritis
Juvenile idiopathic arthritis (JIA) is the most common rheumatologic disease in children. The main symptoms of JIA, which are often the primary focus of treatment, include joint swelling, stiffness, and tenderness.
- Trial name
- NCT07217782
- Testing
- Pressure pain thresholds (measured in kilopascal), Cold pain tolerance (duration in seconds)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Labor Pain and to Reduce Pain, Childbirth
Breathing Exercises Guided by Student Midwives During Labor
This randomized controlled trial aimed to evaluate the effect of breathing exercises applied under the guidance of student midwives during labor on labor pain, labor duration, and birth satisfaction.
- Conditions
- Labor Pain and to Reduce Pain, Childbirth, Normal Labor
- Trial name
- BREATH (NCT07357246)
- Testing
- Guided Breathing Exercises During Labor, Routine Intrapartum Care
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Antalya Bilim University
Breast Cancer, Breast Cancer Screening
Instagram and Podcast Intervention for Breast Cancer Awareness and Screening
Breast cancer is the most common cancer among women worldwide. This randomized controlled trial aims to evaluate the effect of an Instagram- and podcast-based intervention on women's breast cancer awareness, health beliefs, and…
- Trial name
- NCT07673588
- Testing
- Instagram-Based Breast Cancer Awareness Intervention, Instagram-Podcast-Based Breast Cancer Awareness Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Ankara University
Systemic Sclerosis
Sirtuin 3 and Sirtuin 7 in Systemic Sclerosis
Systemic sclerosis (SSc) is a systemic autoimmune disease in which inflammation and fibrosis play a crucial role and lead to severe damage and failure of multiple organs such as the skin, joints, tendons, gastrointestinal tract…
- Trial name
- NCT04303208
- Testing
- Blood sample
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Atopic Dermatitis (AD)
A Study of NOR-101 in Healthy Adults and Adults With Moderate-to-Severe Atopic Dermatitis
This Phase 1 study will assess NOR-101, an investigational study drug, in two parts. Part 1 is a randomized, blinded study comparing single and multiple doses of NOR-101 with placebo in healthy adults.
- Trial name
- POLARIS-1 (NCT07904689)
- Testing
- NOR-101
- Where
- Australia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- North Immunology Inc.
Mechanical Ventilation Complication, Pediatric ALL
Measuring Thickness of the Normal Diaphragm in Children Via Ultrasound.
Critically ill children treated with invasive mechanical ventilation (iMV) in a paediatric intensive care unit (PICU) may suffer from complications leading to prolonged duration of ventilation and PICU stay.
- Conditions
- Mechanical Ventilation Complication, Pediatric ALL, Intensive Care Unit Acquired Weakness
- Trial name
- NCT04589910
- Testing
- diaphragm thickness and thickening fraction
- Where
- Netherlands
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
HIV
Bioequivalence Study of CRushed TriUMeq With or Without Drip Feed Compared to the Whole Tablet
Dolutegravir is an HIV-1 integrase inhibitor which is marketed as a single tablet (Tivicay®) and in a fixed dose combination tablet with abacavir and lamivudine (Triumeq®, referred to as TRI).
- Trial name
- SCRUM (NCT02569346)
- Testing
- Triumeq, Triumeq crushed + breakfast, Triumeq crushed + drip feed
- Where
- Netherlands
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Scar Tissue or Healthy Skin
Measurement and Comparison of the Occlusive and Hydrating Capacity of Three Silicone Gels and One Gel Cream
Study hypothesis: Is Alhydran gel-cream as efficient as silicone gel for skin occlusion and hydration? For this study 16 volunteers and ten patients with healed full thickness burns will be included.
- Trial name
- NCT01413789
- Testing
- Dermatix, Kelocote, BAP scar gel
- Where
- Belgium
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Acne Vulgaris
Dry Eye Disease With Isotretinoin ISOTRETINOIN
The study aims to explore the effects of isotretinoin therapy on the dry eye parameters in acne vulgaris patients \& determine if it is dose-dependent or not.
- Trial name
- NCT06725290
- Testing
- Ocular Surface Disease Index (OSDI) questionnaire
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy
A Study to Learn How Different Amounts of the Study Medicine Called PF-08049820 Are Tolerated and Act in the Body in Healthy Adults
The purpose of this study is to learn about the safety of the study medicine called PF-08049820 in healthy adults. The study will also see: how the body processes the study medicine and if food affects the amount of study…
- Trial name
- NCT06686797
- Testing
- PF-08049820
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Pfizer
Anxiety, Dental, Fear, Dental
Evaluation of Audio-Visual Distraction Technique on Child's Anxiety
Audio-Visual (AV) Distraction is a recent modality introduced to the entertaining market technology for adults and children. Some practitioners started using this modality of distraction in the dental practice to aid in…
- Trial name
- NCT03229720
- Testing
- Nibiru 3D Virtual Reality Headset
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Disease Activity
14.0- 3.0- 3.0- η Protein With Rheumatoid Arthritis
Aim of work: to explore the potential association between serum 14.0-3.0-3.0- η protein level with disease activity and bone mineral density (BMD) in Egyptian patients with rheumatoid arthritis (RA).
- Trial name
- NCT05366608
- Testing
- Serum level of 14.0- 3.0- 3.0- η protein and IL_.6
- Where
- Egypt
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Axial Spondyloarthritis, Psoriatic Arthritis
RAFTLIN-1 Levels in Axial Spondyloarthritis and Psoriatic Arthritis
Unlike other rheumatic diseases, acute phase reactants such as C-reactive protein and erythrocyte sedimentation rate are not diagnostic for patients with Spondyloarthropathies (SpA).
- Trial name
- NCT05771389
- Testing
- serum raftlin-1 protein levels
- Where
- Turkey (Türkiye)
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Wrinkle
BTL-785F Device for Improving the Structure of Facial Muscles
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive facial remodeling and investigate its effect on muscles and wrinkles.
- Trial name
- NCT05524740
- Testing
- BTL-785-7
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Neurocognitive Development
A Sub-study of PREDICT Neurodevelopment Protocol
To determine the neurodevelopment (ND) in normal children in Thailand and Cambodia and to use this group to compare the neurodevelopmental changes over time to the HIV-infected children with and without HAART (main study).
- Trial name
- NCT02406768
- Where
- 10 sites in Cambodia, Thailand
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The HIV Netherlands Australia Thailand Research Collaboration
Skin Laxity
Post-Market Lower Eyelid Treatment With Renuvion in Greece
This is a prospective, multi-center, non-randomized, single-arm study of up to 15 subjects treated with the Renuvion APR System.
- Trial name
- NCT05605691
- Testing
- Renuvion APR System
- Where
- Greece
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Apyx Medical
Breast Cancer
INVINCIBLE TRIAL: Intratumoral INT230-6 in Breast Cancer
This is a phase II, randomized, multi-center, parallel design, window of opportunity trial evaluating intratumoral INT230-6 in up to 90 patients with early stage breast cancer.
- Trial name
- NCT04781725
- Testing
- INT230-6, Saline injection
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Breast Cancer, Aromatase Inhibitors
Combined Training on Body Composition of Postmenopausal Women Undergoing Treatment for Breast Cancer
Breast cancer is a multifactorial disease affecting women, and one of the treatments for its healing and survival is hormone therapy.
- Conditions
- Breast Cancer, Aromatase Inhibitors, Postmenopausal
- Trial name
- NCT02804308
- Testing
- Combined Training
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
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